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mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Frankia alni (strain ACN14a)
Length
206 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
22.17 kDa
Sequence
MTYLTTWTADARPRLLEETTDPARIAAVLAAIAVRFERWPLAPGLPAGAEAEDILAAYRSRIDALSAAEGFVLVDVAALHPSAAADWREVAAAARARFLAEHTHDDDEIRFFAAGSGVFYLHVDERVQAVRCEAGDLISVPKGTTHWFDMGVEPDFAAVRFFRAEDGWVGAFTGSDIATRIPDFDALARRSSSAAQPQAEAPAAAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain CC9311)
Length
202 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
22.643 kDa
Sequence
MTELRIYATRGAGVEADRDSAVAAAPEALLSTSNAEQISAQLKTRGIKFQRWPSKPKLEQGAMQEQILEAYASLIASVQKNEGYQTVDVMRVERDQISGSTLRQTFRQEHQHAEDEVRFFVEGCGLFALHIKDEVLQVICEANDWIAIPAGTRHWFDMGVDPNYCVIRFFKNSGGWAASFTHDPIADHYPGLDQARKQTTQG
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus elongatus (strain PCC 7942)
Length
198 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
22.35 kDa
Sequence
MTVLTIYREDLPEQPLTQTTDAAEIAALLAQQGLRFERWPAQVELADDATPEQILAAYATEVDRVKTEGGYITVDAVSLRPDHPDRAALRQKFLAEHIHSEDEVRFFVAGQGLFSLHLGDHVYALLCTQNDWISVPAGTRHWFDMGSQPYFTALRFFNNPRRLGRSVYRQRHRQSVPAPALNSGSERDNFILSLALAC
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Length
197 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.61 kDa
Sequence
MTLLTTWPESGPETVVRRTSDPAEIAAALAPLGVRYEQWPVRADVPADADSDTVFAAYGPEIDRLNAEEGFTTVDVLGLHPSDDPEYPVKAKAARAKFLQEHTHDDDDEVRFFVSGSGIFYLHVNGEVHAVYCEKGDLLGVPRGTTHWFDMGTRPAFTAIRFFHEEDGWIGSFTGSTIASRFPDYDTIHAGHVGSAA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Length
190 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.655 kDa
Sequence
MSLLTVWPDTDAGTVELRTEDPQEITDVLKQFGVSFSRWELRELPERPSSEEVLEAYRAEVDEVIEREGYIKVDAAVMAPSQDPQWPAQAKAAREKFLSEHTHDDDEDRFFARGAGVFYLHIGDRVYAMLCEAGDLLSVPANTTHWFDMGTEPDFVAIRFFHDDDGWVGAFLNTDTAEKFPTFDELMASR
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Gluconobacter oxydans (strain 621H)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.613 kDa
Sequence
MSRLTVYRDDAPDTILLDVTTPGEIAETLRPHNIRFDRWSAPITPAPDAPAEEVLDAYRPYLDTLMGETGAGSADVVRINASTPNLPELRKKFLSEHTHSEDEVRFFVHGQGAFVLHIRGRVYSVLCTQGDLISVPAGIPHWFDAGPSPDVVALRVFTDTTGWIAQYTGDDIANRFPAEVPVEASGNS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.23 kDa
Sequence
MSRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPKKPHKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.259 kDa
Sequence
MSRLRIFADTNPATPEFDSRDGDAIAAQLQKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPHKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.402 kDa
Sequence
MSRLRIFADSNPTTPHFDSRDGEQIATELRKIGVTFERWHASQPVEPGASPEQVMAAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAQVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPPKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas campestris pv. campestris (strain B100)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.402 kDa
Sequence
MSRLRIFADSNPTTPHFDSRDGEQIATELRKIGVTFERWHASQPVEPGASPEQVMAAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAQVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPPKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.402 kDa
Sequence
MSRLRIFADSNPTTPHFDSRDGEQIATELRKIGVTFERWHASQPVEPGASPEQVMAAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAQVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPPKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.306 kDa
Sequence
MSRLRIFADTNPATPEFDSRDGDAIASELKKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPHKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.306 kDa
Sequence
MSRLRIFADTNPATPEFDSRDGDAIASELKKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPHKAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xylella fastidiosa (strain M23)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.393 kDa
Sequence
MSRLRIFDDHTPDTPFFVSKEQAQITAELHKIGITFERWEATQAIEPGATAEQVMAAYRTDIDRLIATHGFKTVDVISIAPDNAKREEMRAKFLEEHFHKEDEVRFFVAGSGLFTVHSGNKVYEIECVKNDLIAIPDGTLHWFDMGAAPYFVAIRFFTEPDGWVGHFTGTDIAQRFPRYIPEGCQSAH
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xylella fastidiosa (strain 9a5c)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.446 kDa
Sequence
MSRLRIFDDHTPDTPFFVSKEQTQITAELHKIGITFERWEATQAIEPGATPEQVMAAYRADIDRLIATHGFKTVDVVSIAPDNPKREEMRAKFLEEHFHKEDEVRFFVAGSGLFTVHSGNKVYEIECVKNDLIAIPDGTQHWFDMGAAPYFVAIRFFTEPDGWVGHFTGTDIAQRFPRYIPEGCQSAH
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xylella fastidiosa (strain M12)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.362 kDa
Sequence
MSRLRIFDDHTPNTPFFVSKEQAQITAELHKIGITFERWEATQAIEPGATAEQVMAAYRADIDRLIATHGFKTVDVISIAPDNAKREEMRAKFLEEHFHKEDEVRFFVAGSGLFTVHSGNKVYEIECVKNDLIAIPDGTLHWFDMGAAPYFVAIRFFTEPDGWVGHFTGTDIAQRFPRYIPEGCQSAH
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
188 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.393 kDa
Sequence
MSRLRIFDDHTPDTPFFVSKEQAQITAELHKIGITFERWEATQAIEPGATAEQVMAAYRTDIDRLIATHGFKTVDVISIAPDNAKREEMRAKFLEEHFHKEDEVRFFVAGSGLFTVHSGNKVYEIECVKNDLIAIPDGTLHWFDMGAAPYFVAIRFFTEPDGWVGHFTGTDIAQRFPRYIPEGCQSAH
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Length
186 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.077 kDa
Sequence
MSLLTIHPESGTSAPEIIREGDAIAARLAEIGVLFERWQAGRAFEPDAEQQTILAAYADSVERLKAKYGFESADVISVGPDHPQKDELRARFLREHTHSDFEVRFFVEGRGLFYLHPGDRVYAILCERGDLLSVPSNTRHWFDMGAEPCLKCIRLFTTAEGWVADFTGSDIGDRFPRLEDYLKHYA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain CC9902)
Length
186 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.761 kDa
Sequence
MSRLSIFPDGSTSMDQSSPTPLLVTETPAEIQAELARRGIGFEQWPALQELPLAADQSWILKAYANEIDRVKRDGGYATVDAIRMTPDHPERVALRSKFLAEHTHAEDEVRFFVEGRGLFCLHLGAEVLLTLCERGDLIRVPAGTKHWFDMGGQPAFCAVRWFNNAVGWVATFTGNTISERFPTLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain CC9605)
Length
186 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.925 kDa
Sequence
MSRLSIFPDETAANAPDGLVPQLESNDPAVIQASLSRRGIGFEQWPAEHGLPEGADQATILQAYADAIAWVQRDGGYFTVDAIRMTPNHPDREPLRRKFLEEHTHAEDEVRFFVEGCGLFVLHIGSEVLSVLCERGDLMRVPAGTRHWFDMGSQPRFCAVRWFNNPEGWVAQYTGSSISQRFPRLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain WH8102)
Length
186 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.628 kDa
Sequence
MSRLSIFPDHGDGGDGALPLPKLVCNDPASIQAELADRCVGFEQWPAAHALPPDADQSTILTTYASEVARVQRDGGYQTVDAIRMTPDHPEREALRNKFLSEHTHAEDEVRFFVEGQGLFSLHIDKEVLVTLCERGDLISVPAGTRHWFDMGPTPSFCALRFFNNSEGWVATFTGDSIAERFPRLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.087 kDa
Sequence
MTTLSIFHQNQPEQAQTVVTDPDTIRNKLSAHGVHFDRWATRDLPADATQEEILEAYADEVARLKQDWGFQTADVVSLTADHPQKDAFRQKFLDEHTHSEDEVRFFVRGQGLFYLHFGDQVYALLCEKNDLISVPDGTRHWFDMGPEPEFTCIRLFSNPEGWVASFTGEDIASRLPRYESLAGGA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Prochlorococcus marinus (strain MIT 9303)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.717 kDa
Sequence
MSRLSIHPEGNTNATSPAEPLLESDDPAVIKAELAKRGIEFQHWPAKVKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEVLQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Prochlorococcus marinus (strain MIT 9313)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.649 kDa
Sequence
MSRLSIHPEGSTNATSPAEPLLESDDPAVIKVELAKRGIAFQRWPAKVKLDQNSSESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLDEHTHAEDEVRFFVEGCGLFCLHIGAEVLQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIANFTGDAIAERFAKLP
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Hahella chejuensis (strain KCTC 2396)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.363 kDa
Sequence
MSSLRIYNDNDFSQPLVFTEDGAEISRQLNEAGIRFERWSTRELDEGATPDSILAAYQEEVEKLKAENGFTTADVVSLTPAHPQKDEFRKKFLDEHRHSEDEVRFFVRGQGLFYLHLEDKVYVVLCRKNDLISVPNGTKHWFDMGPEPEFTCVRLFTNPEGWVAQFTGDEIASKAPRFEQLIEEA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Stenotrophomonas maltophilia (strain R551-3)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.807 kDa
Sequence
MSRLRIYDDTRPESPLLDTQDGAIIAAELQKIGVTFERWQATAPVAPGASQEEVFAAYRADIDRLVAERGFKSVDVASIAPDNPNRAELRRKFLDEHFHKEDEVRFFVAGSGLFTLHVGDKVYEIECVKDDLIAVPDGTTHWFDMGDEPSFVAIRFFTEPDGWVGHFTGTDIAQKFPRYVPTQAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Stenotrophomonas maltophilia (strain K279a)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.765 kDa
Sequence
MSRLRIYDDTRPESPLLDTQDGAVIAAELQKIGVTFERWQATAPVAPGASQEEVFAAYRADIDRLVAERGFKSVDVASIAPDNPNRAELRKKFLDEHFHKEDEVRFFVAGSGLFTLHVGDKVYEIECVKDDLIAVPDGTTHWFDMGDEPSFVAIRFFTEPDGWVGHFTGTDIAQKFPRYVPTQAS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain RCC307)
Length
185 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.63 kDa
Sequence
MSQLTIYNAVSEGNDPPLPSLHTTDAAIVAAELSQRGIRFQQWPTHDELDAASSQEEILAAYSAEIAEVQAAGGYQTVDAISLGPDHPQRAELRQKFLSEHTHSEDEVRFFVDGRGLFCLHIGDEVLQVLCERNDWLSVPAGTRHWFDMGERPCFSAIRFFNNQDGWVAQFTGDPIAKRYPLLGS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Length
184 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.487 kDa
Sequence
MTHLTVYPDTDPATVLLDTRDGAEIAASLSGIGVVFERWDAPHALGEDADQTAVLAAYEADVKRLMDEGGYKSVDVVRVKPDNPNRAEMRQKFLAEHTHDDDEVRFFVEGAGAFYLRKDGRVYRVVCERNDLISVPAGTTHWFDTGAAPHFCAIRIFTSPEGWVGHFTGDDIATRFPKFESEPQ
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Aquifex aeolicus (strain VF5)
Length
183 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.478 kDa
Sequence
MSRLRIYTESGELIKDITDPKEIAEELQKINVLFERWRANAPLKENASDEEIINAYKHEIDRLINKYGFQSYDVIAMTPEHPKKDELRQKFLKEHTHSDFEVRYFVYGDGVFYLHPNDKVYILHCTAGDLISVPPNTKHWFDMGENPNFKCIRLFTTPEGWVAEYTGSDIAEKFPKYEEVVNG
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length
183 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.442 kDa
Sequence
MTQLIVYEAGNPSHVLLQTSDFDVIAGKVAALGARIERWEARHPIAPGASNEEVLSAYGHEIDRLKRERGYTNGDVVRIKPGNPNWPELRGKFLQEHVHVEDEVRFFVEGTGAFYLHLDDKVYQLVGEAGDLLSVPHGVKHWFDGGPEADFTCIRLFTNQEGWVAHFTGDAISDAFPKYEIAA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Hydrogenobaculum sp. (strain Y04AAS1)
Length
183 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.164 kDa
Sequence
MSHLVIYNEEGSVLELIKEYEAVSKRLAALGVRFERWKADNELSWDAGQKEVIKAYEEDINRIIKEFGFKSLDVVSLIPENPKKDELRNVFLKEHTHSDFEVRFFVDGSGTFYLHIDDKVYVAFCEKGDFISVPAYTKHWFDMGSKPFFKAIRFFLIPEGWVADFTGSDISLKIPSHDDIASL
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Microcystis aeruginosa
Length
183 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.846 kDa
Sequence
MAILRLENGTTYTQLADISLELAKLNVTLNYWPIENEATRQLLKEASLTDEEKEIVLTSLDGYFEQLKQEAGYQARDLIVLHPDIANLDTLLAKFERCHTHADDEVRYIIDGEGVFGFVFPDGSQGELTIQPQEYINVPAHSEHWFHLTASKRVKAVRYFTTTAGWVPEYTETVIRFPSLTAV
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Microcystis aeruginosa (strain NIES-843)
Length
183 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.819 kDa
Sequence
MAILRLENGTTYTQLADISLELAKLNVTLNYWPIENEATRQLLKQASLTDEEKEIVLTSLDGYFEQLKQEAGYQARDLIVLHPEIANLDTLLAKFERCHTHADDEVRYIIDGEGVFGFVFADGSQGELTIQPQEYINVPAHSEHWFHLTASKRVKAVRYFTSTAGWVPEYTETVIRFPSLTAV
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length
182 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.362 kDa
Sequence
MATLLLEDGTIESNLDEIARELAPLGVYIKHYDPGTSILFPHLLIQDALTDKEKCHIVDLHNSVFEFIQQENGYLWCDLLNVHPGSPNLQTLIATYAKYHTHTAPEALYVLAGEMIFGFVKPDGSQVQLLVQSQDYLHIPSGVEHWCSLTASLSFKAVRYFTAADGWVPNYTGTQLNDSLNK
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
182 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.447 kDa
Sequence
MATLLLEDGTIESNLDEIVRELAPLGIYLKHYDPGTSILFPHLLTQDALTDKEKCHIVDLHNSVFEFIQQENGYLWCDLLNVHPGSPNLQTLIATYAQYHTHTAPEALYVLAGEMIFGFVKPDGSQVQLLVQSQDYLHIPSGVEHWCSLTASLNFKAVRYFTAADGWVPNYTGTRLNDSLNK
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.558 kDa
Sequence
MHSELKVFSDQAPGRVEQHLTDKAAMARVLASAGIRYEQWQANQALSDDPQQDEVIQAYQADIDRLIADEGYQTVDVVSMVPDHPEKTAFRQKFLEEHRHSEDEVRFFVEGQGLFTLHINGKVYEVLCSKGDLISVPANTPHWFDMGPEPRFVAIRLFNNPDGWVANFTGSDIAQQFNRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.366 kDa
Sequence
MSSLSVFHVSSPDTPNKVLTHLEDIASTLGEHGVAFDRWEAAAPITPGASQEEVISAYRTQIDKLMTEHGYVTVDVISLNSDHPQKAELRAKFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVMCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas aeruginosa (strain PA7)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.54 kDa
Sequence
MSSLTVYHESQPEQPLKLLTHAEDIASTLAEVGVRFERWEAAAPIAAGASQEEVIAAYAHEIERLKRERGYITVDVVSLDSDHPQKAELRAKFLDEHRHGEDEVRFFVAGRGLFVLHIEEHVYAVLCERNDLISVPAGTRHWFDMGEHPHFVAVRLFNNPEGWVAQFTGDDIASRFPLLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.552 kDa
Sequence
MSSLTVYHENQPEQPLKLLTHAEDIASTLAEVGVRFERWEAAAPIAAGASQDEVIAAYAHEIERLKRERGYITVDVVSLNSDHPQKAELRAKFLDEHRHGEDEVRFFVAGRGLFVLHIEEHVYAVLCERNDLISVPAGTRHWFDMGEHPHFVAVRLFNNPEGWVAQFTGDDIASRFPLLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.552 kDa
Sequence
MSSLTVYHENQPEQPLKLLTHAEDIASTLAEVGVRFERWEAAAPIAAGASQDEVIAAYAHEIERLKRERGYITVDVVSLNSDHPQKAELRAKFLDEHRHGEDEVRFFVAGRGLFVLHIEEHVYAVLCERNDLISVPAGTRHWFDMGEHPHFVAVRLFNNPEGWVAQFTGDDIASRFPLLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.352 kDa
Sequence
MSSLSVYHVSSPDLPNKVLTHFDDIAATLAEQGIRFDRWPATTRVAPGTSQQEVICAYQEQVDRLMTEGGYASVDVISLDEDHPRKAELRASFLDEHRHSEDEVRFFVAGRGLFNLHIDDYVYAVLCERNDLISVPAGTAHWFDMGERPNLVAIRMFNNPQGWNASLTGDAIASQFPRLDD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.546 kDa
Sequence
MSSLSVYHVSSPEIPNKVLTHFEDIASTLAEQGVRFDRWQAAAKIQPGASQEEVIGAYKEQIDKLMTERGYITVDVISLNSDHPQKAELRAKFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTKHWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.461 kDa
Sequence
MSSLSVYHVSSPDIPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVINAYRTQIDTLMTRHGYVTVDVISLNSDHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNPDGWVANFTGEDIAGRFPRLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.458 kDa
Sequence
MSSLSVYHVSSPDMPNKVLTHLEDIASTLAEHGVAFDRWEAATPITPGASQEEVISAYRTQIDTLMTERGYVTVDVISLNSDHPQKAELRARFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTRHWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLED
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Pseudomonas stutzeri (strain A1501)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.504 kDa
Sequence
MSVLSVYHESRPEQPLKVLTHLEDIAATLAEVGVQLERWDASAPVAAGASQEDVIAAYRPQIDRLMAERGYVTVDVISVSRDHPQKDELRAKFLDEHRHAEDEVRFFVAGRGLFTLHIEDMVYAVLCEKNDLISVPAGTRHWFDMGEQPSFVAIRLFNNPDGWTAQFTGERIADQFPRLDD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Trichodesmium erythraeum (strain IMS101)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
21.049 kDa
Sequence
MAILKLEDGTIYTQLHDISRELSSLNIQLNHWPVGDNLETHNLLEKDVLSDDQKEEFLQSVDHYFEELKETAGYQSRDLLAIHPEIPNLDAILSKFDKCHTHADDEARYIVAGICIFGFVRPDDSQVELTLQPQEYINIPANTEHWFYLTPEKRVKAVRYFSSTEGWTPHYTSTEIHFKKS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Sodalis glossinidius (strain morsitans)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.553 kDa
Sequence
MRALTIYSDTDATAPRWQSHEGDAIQRELNAIGVRFERWQTDRELGANPDADTVIAAYQDAIDRLVAEKGYQSWDVISMRPDNPQRETLRTKFLAEHTHGEDEVRFLVEGAGLFCLHVQGKIYQILCEKNDLISVPAGTAHWFDMGEAPSFTAIRVFDNPEGWIARFTGDAIADEYPRLVR
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
Length
181 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.245 kDa
Sequence
MTVLTIYREDLPEQPLTQATDGAAEIAALLAQQGLRFERWPAQVELADDATPEQILAAYATEVDRVKTEGGYITVDAVSLRPDHPDRAALRQKFLAEHIHSEDEVRFFVAGQGLFSLHLGDHVYALLCTQNDWISVPAGTRHWFDMGSQPYFTALRFFNNPEGWVAQFTGSDIASQFPLLP
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Acidiphilium cryptum (strain JF-5)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.872 kDa
Sequence
MSTLRIFDDANPDAPLVATSDAARMAAELKSIGVRFERWESPVAIAADASPEEILEAYRPYLDRLMGETGAGSADVIKMTPDHPQAGTLREKFLNEHIHTEDEVRFFVRGSGHFVMHLDGKVYDAYCTEGDLISVPANTRHWFDAGSTPDFIALRIFTDTSGWVAHFTGDQISARFPVAA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.162 kDa
Sequence
MSALTIYSDKDASQPQWHSTDAAEIAQQLNAKGVRFERWVADRDLGQAPAPETVITAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALRAKFLNEHTHGEDEVRFFVEGAGLFCLHIGDQVYQVLCEKNDLISVPAGTPHWFDMGSEPNFTAIRIFDNPEGWVAQFTGDAIADAYPRLL
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Klebsiella oxytoca
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.329 kDa
Sequence
MSALTIFSVKDPQNSLWHSTNAEEIQQQLNAKGVRFERWQADRDLGAAPTAETVIAAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALREKFLNEHTHGEDEVRFFVEGAGLFCLHIGDEVFQVLCEKNDLISVPAHTPHWFDMGSEPNFTAIRIFDNPEGWIAQFTGDDIASAYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.225 kDa
Sequence
MSALTLFSVTDPQTPVWHSTDAKAIQAQLNAKGVRFERWQADRDLGANPSPETVIAAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALREKFLNEHTHGEDEVRFFVEGAGLFCLHIGDEVFQVLCEKNDLISVPAHTPHWFDMGSEPNFTAIRIFDNPEGWIAQFTGDDIASAYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Cronobacter sakazakii (strain ATCC BAA-894)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.25 kDa
Sequence
MSALTIFADNGASEPLWQSTDADAIREQLNAQGVRFERWQADRELGDNPTPETVLTAYQHAIDLLVAEKGYQSWDVISMRADNPQKEALRDKFLNEHTHGEDEVRFFVEGAGLFCLHIGDKVYQVLCEKNDLISVPAGTPHWFDMGSEPHFTAIRIFDNPEGWIANFTGSPIAEAYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Cronobacter sakazakii
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.148 kDa
Sequence
MSALTIFADNGASEPLWQSTDADAIREQLNAQGVRFERWQADRDLGDDPTPEAVLTAYQHAIDLLVAEKGYQSWDVISMRADNPQKEALRGKFLNEHTHGEDEVRFFVEGAGLFCLHIGDKVYQVLCEKNDLISVPAGTPHWFDMGSEPHFTAIRIFDNPEGWIANFTGSPIAEAYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Enterobacter sp. (strain 638)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.38 kDa
Sequence
MSALTIYSETETREPLWHSTDAAEIADKLNARGVRFERWEADRDLGQDPAAETVINAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALRAKFLNEHTHGEDEVRFFVEGAGLFCLHIDDQVYQVLCEKNDLISVPAGTPHWFDMGSEPNFTAIRIFDNPEGWIAQFTGDAIADAYPRLP
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.262 kDa
Sequence
MSALTIFTESEATTPVWYSMDAAEMAEKLGSKGVRFERWQADRDLGDNPDPETVIGAYQHAIDRLVAEKGYQSWDVISMRADNPQKEALRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDGHIFQVLCEKNDLISVPAGTPHWFDMGSSPHFTAIRIFDNQEGWIAKFTGDPIADGYPRLP
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Geobacillus kaustophilus (strain HTA426)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.622 kDa
Sequence
MAVIKVRKTGQVIEGEDNVRAFLNSQGVLYEHWDITKLPEHLRDKYVLTDEEKNEILATFKDEIEDLAARRGYKTWDIVALSDATPNLDELLKKFEQVHIHTEDEVRAITAGHGIFIIKGDKETGYFDVELEAGDVISVPEGNPHYFTLMDDRRVVAVRLFIDPSGWVAHPYEEKEEAVQ
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.597 kDa
Sequence
MAVIKVKKTGQVIEGEDNVRAFLNSQGVLYEHWDITKLPEHLRDKYVLTDEEKEEILATFKDEIEDLAARRGYKTWDIVALSDATPNLEELLKKFEQVHIHTEDEVRAITAGHGIFIIKGDKETGYFDVELEAGDVISVPEGNPHYFTLMDDRQVVAVRLFIDPSGWVAHPYEEKEEVNS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Serratia proteamaculans (strain 568)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.527 kDa
Sequence
MSGLTIFSDQEPQQPLWQSRDAQAIGQQLAQIGVRFERWQADRELGENPDPAVVIAAYQHQIDRLVAEKGYQSWDVISMRPDNAQREVLRSKFLSEHTHGEDEVRFFVEGAGLFCLHLDGKIFQILCEKNDLISVPANTRHWFDMGSAPNFTAIRVFDNPEGWVAHFTGDNIADAYPRLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Sorangium cellulosum (strain So ce56)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.351 kDa
Sequence
MSRLRVYRESDPTRADEYTTLEDIARVAAEAQIRFERWSAERPLPPGAAQEQVLEAYAGPVKQLSEACGFVTADVVSVSPGTPNHPELRRKFLDEHIHTEDEARFFVEGRGLFCIHHGERVLSFLVEKGDLISVPAGTRHWFDMGPEPSFTCIRWFSDPKGWVAEHTGSDIASRFPRLEA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain WH7803)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.56 kDa
Sequence
MSELSIYSEQGGEPVFSTLDSARIQHELSLRGIAFDRCASKAEIALDADQADILSTYAEEIHRIQALGDYPTVDAIRMKPDHPDRQALRQKFLSEHTHAEDEVRLFVEGRGLFCLHIKSEVLQVTCETNDWISVPAGTRHWFDMGEKPYFCAIRFFNNPNGWVANFTNDPIAERFSKLRD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.854 kDa
Sequence
MSGLTIFSDEQPEQPLWQSRDAEEIQQQLTAIGVRFERWQADRELGENPQPDAVIAAYQHEIDRLVAEKGYQSWDVISMRPDNEQREVLREKFLSEHTHGEDEVRFFVEGAGLFCLHLNSKIYQILCEKNDLLSVPADTPHWFDMGSKPNFTAIRVFDNPEGWVARFTGDKIADSYPRLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.585 kDa
Sequence
MSGLTIFSDQQPEKPLWQSHNAEEIQQQLTAIGVRFERWQADCELGENPQPEAVIAAYQHEIDRLVAENGYKSWDVISMRPDNPQREALREKFLSEHTHGEDEVRFFVEGSGLFCLHLNEKVYQILCEKNDLLSVPADIPHWFDMGSAPNFTAIRVFDNPEGWIARSTGDNIADGYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.585 kDa
Sequence
MSGLTIFSDQQPEKPLWQSHNAEEIQQQLTAIGVRFERWQADCELGENPQPEAVIAAYQHEIDRLVAENGYKSWDVISMRPDNPQREALREKFLSEHTHGEDEVRFFVEGSGLFCLHLNEKVYQILCEKNDLLSVPADIPHWFDMGSAPNFTAIRVFDNPEGWIARSTGDNIADGYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia pestis bv. Antiqua (strain Angola)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.585 kDa
Sequence
MSGLTIFSDQQPEKPLWQSHNAEEIQQQLTAIGVRFERWQADCELGENPQPEAVIAAYQHEIDRLVAENGYKSWDVISMRPDNPQREALREKFLSEHTHGEDEVRFFVEGSGLFCLHLNEKVYQILCEKNDLLSVPADIPHWFDMGSAPNFTAIRVFDNPEGWIARSTGDNIADGYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia pestis (strain Pestoides F)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.585 kDa
Sequence
MSGLTIFSDQQPEKPLWQSHNAEEIQQQLTAIGVRFERWQADCELGENPQPEAVIAAYQHEIDRLVAENGYKSWDVISMRPDNPQREALREKFLSEHTHGEDEVRFFVEGSGLFCLHLNEKVYQILCEKNDLLSVPADIPHWFDMGSAPNFTAIRVFDNPEGWIARSTGDNIADGYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.585 kDa
Sequence
MSGLTIFSDQQPEKPLWQSHNAEEIQQQLTAIGVRFERWQADCELGENPQPEAVIAAYQHEIDRLVAENGYKSWDVISMRPDNPQREALREKFLSEHTHGEDEVRFFVEGSGLFCLHLNEKVYQILCEKNDLLSVPADIPHWFDMGSAPNFTAIRVFDNPEGWIARSTGDNIADGYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Length
180 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.586 kDa
Sequence
MSGLTIFSDQQPEKPLWQSHDAEEIQQQLTAIGVRFERWQADCELGENPQPEAVIAAYQHEIDRLVAENGYKSWDVISMRPDNPQREALREKFLSEHTHGEDEVRFFVEGSGLFCLHLNEKVYQILCEKNDLLSVPADIPHWFDMGSAPNFTAIRVFDNPEGWIARSTGDNIADGYPRLA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
179 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.865 kDa
Sequence
MATIRIHDEQNTSIENQEEVEQFLKRQEVIYEKWDITKLPAGLKEKYDLTDEEKQEILDVFAAEIKDISERRGYKASDVISLSDQNPKLDELLKNFKQEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVLLNPGDLISVPENTRHYFTLQEDRKVVAVRIFVTTEGWVPIYEKENVNQS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)
Length
179 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.463 kDa
Sequence
MATVLFQKTNERYTDQNEVSAFLASRGVLYEQWDVSKLPAELVDTYTLTDADKQTILDTFQSEITDVSERRGYQTADIISLSDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGVFAIQDDEVGYYNIELNPGDLISVPVNTRHYFTLQEDRKVVAVRIFVTTDGWVPIYEKDPIETAN
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5)
Length
179 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.647 kDa
Sequence
MSHLTVYRDDDPDDIVLRTDDAAVIADALRGIGARFERWDSPVVPPLDATPDAVLNTYRPYLDELMGETGAGSADVVRINAATPNLTALRDKFLSEHTHSEDEVRFFVHGSGNFVLHVDGRVYDVCCTAGDLISVPRGTPHWFDAGLSPDVVALRVFTDTTGWIADYTGDDIARRFPVS
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length
179 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.838 kDa
Sequence
MSRLTIYADSTPDAPLLRTEDPERIAQELSSIGVRFERWSSAVTPSPDDDEATILAAYRPYLNALMGETGAGTADVIRLRPDTPNLPALRQKFLSEHTHTEDEVRFFVHGSGNFILHVDDRVYDAHCTQGDLISVPTGIKHWFDAGETPFVTALRVFTDTTGWVAHYTGDPIADHFPAA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Sulfurihydrogenibium sp. (strain YO3AOP1)
Length
179 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.78 kDa
Sequence
MARLVFRKNGKVIENPEEIKSFLSQYGVVYDVWGVDRLPEDVRKNYDIDEENSKAIIQAYEKELKELKEKMGYITEDIVVLSEKTPNLDGLMAKFKREHHHIDDEVRFVVDGSGIFPVKIEDDIVDIHVEAGELIVVPAGARHWFELDENRKIKCIRVFKTPAGWEAIYNENETATMRD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus subtilis (strain 168)
Length
178 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.824 kDa
Sequence
MATIRIHDEANTTIENQEEVASFLDSQEVIYEQWDITRLPEHLSEKYDLTEEEKQQILDTFETEIKDISTRRGYKAQDVISLSDSNPKLDELLENFKREHHHTDDEVRFIVSGHGIFVIQGQDGTFFDVRLNPGDLISVPENIRHYFTLQEDRKVVAVRIFVTTEGWVPIYEKDSVNQ
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)
Length
178 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.945 kDa
Sequence
MATIRIHDEKNTLIEHQEEVARFLDEQEVIYEQWNIEKLPSELSEKYDLTEDEKERILAVFDTEIQDISARRGYQSQDVISLSDTTPNLDELLKNFQREHHHTDDEVRFIVSGHGIFVIQGKDGTFFDVRLNPGDLISVPENIRHYFTLQEDRRVVAIRIFVTTEGWVPIYENESVQN
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
Length
177 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.227 kDa
Sequence
MATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVVLHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFKDNSGWTPVYVDESKVLINA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Length
177 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.758 kDa
Sequence
MATIVRQKGLAPIEETSEVKSFLKERGIDYDHWKVPYNAADLTDKEILADVEKEELLKKLDDRFETLKEKEGYQSRDLIVLHPNVSGLNDMLAKFDRVHYHTDEEVRYIVDGSGVFGFVLKGEKFLVHVVKDDFISVPRNTNHWFYLDDKKRIKAVRYFRDMSGWVPNYVEETNSLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Length
177 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.758 kDa
Sequence
MATIVRQKGLAPIEETSEVKSFLKERGIDYDHWKVPYNAADLTDKEILADVEKEELLKKLDDRFETLKEKEGYQSRDLIVLHPNVSGLNDMLAKFDRVHYHTDEEVRYIVDGSGVFGFVLKGEKFLVHVVKDDFISVPRNTNHWFYLDDKKRIKAVRYFRDMSGWVPNYVEETNSLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
Length
177 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.227 kDa
Sequence
MATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVVLHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFKDNSGWTPVYVDESKVLINA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Length
177 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.832 kDa
Sequence
MATIVRQNGLTPIQETNEVKSFLKERGIDYDHWKVPHNASNLTDKEVLVDTEKEELLKKLDDRFETLKAKEGYQSRDLIVLHPNVSGLNEMLAKFDKVHYHTDEEVRYIVDGSGVFGFAFKDEKFLVHVYKDDFISVPRNTNHWFYLDDKKRIKAVRYFQDMSGWVPNYVEETNSLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Length
177 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.832 kDa
Sequence
MATIVRQNGLTPIQETNEVKSFLKERGIDYDHWKVPHNASNLTDKEVLVDTEKEELLKKLDDRFETLKAKEGYQSRDLIVLHPNVSGLNEMLAKFDKVHYHTDEEVRYIVDGSGVFGFAFKDEKFLVHVYKDDFISVPRNTNHWFYLDDKKRIKAVRYFQDMSGWVPNYVEETNSLD
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus pumilus (strain SAFR-032)
Length
176 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
20.426 kDa
Sequence
MATILIHNEENTLLESEQEVAAYLENQGVIYEHWDIAKLPNRLSEKYDLTDEEKDEILTVFQKEIESISEKRGYKSQDVISLSDATPNLDDLLQNFQREHHHTDDEVRFIVSGHGIFAIQGKDGVFFDVRLNPGDLISVPPHIRHYFTLQEDRKVVSVRIFVTTEGWVPIYEEETV
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Delftia acidovorans (strain DSM 14801 / SPH-1)
Length
176 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.032 kDa
Sequence
MGALASHRVSDADFVAAIGVQWQHRPLAPEPGLAALLAQAQLDDGGKATVVQAVGMLVVDECVAHGYHSMDLVVLHPGTPGLDEALERFDKPHTHADDEVRYILEGEGLFGFFDAGGQERVLRVQPGDYLRIPAGVEHRFTLTATRRIKALRLFADTAGWVAQYTQRPAAAMEVPA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)
Length
176 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.694 kDa
Sequence
MTTLYQTESKQTLTDPATIKDFLKSHGIWFEQWETPAQLTQEASQADILAAYADVLDPFMAANGYQSADVVNIHSGIENYQAIREKFLAEHTHSEDEVRFFVAGQGLFWFNLDGTAVFNVCCEAGDLISVPQGTKHWFDAGPVPNVKAIRIFSDTAGWTPHYTGSQVEQQYRAITL
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus thuringiensis (strain Al Hakam)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.577 kDa
Sequence
MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSVRRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus anthracis
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.548 kDa
Sequence
MAQIRIHEVNTRIENEVKVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.597 kDa
Sequence
MAQIRIHEINTRIENEVEVSKFLQEEGVLYEKWNISKLPTHLKENYSLTDENKAEILAVFSKEIADVSSRRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.773 kDa
Sequence
MAQIRIHEINTRIENEKEVQLFLQKEDVLYEKWDISKLPAHLQNNYALTDENKEEILTLFSNEIADVSQRRGYKAHDIISLSSATPNLDELLINFKQEHHHTDDEVRFIVSGHGIFAIQGKDGRFFDVELEPGDLISVPENVRHYFTLQDDRQVVAIRIFVTTAGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.567 kDa
Sequence
MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPTHLNENYSLTDENKAEILAIFSKEIADVSARRGYKAHDVISLSSSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGKFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus cereus (strain ZK / E33L)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.549 kDa
Sequence
MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.567 kDa
Sequence
MAQIRIHEINTRIENEVEVSKFLQEEGVLYEKWNISKLPTHLKENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELDPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
170 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
19.738 kDa
Sequence
MAQIRIHEENTRIENEVEVSNFLQGEDVLYEKWNISKLPTHLKENYSLTDENKAEILTLFSKEIADVSERRGYKAYDVVSLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGRFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Length
165 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
18.06 kDa
Sequence
MATLLFDDGREATAAEIEAIARAHRIVVEHRPVPAALAETLARPLLDDTSAATVLDALPPRPEFPSRDLIVLHPDRPDNEQLATKFENWHRHAGDEIRHILDGAGIFGVIVDGQRADLHVGPGDFIVVPAGLEHNFRLTAARRIKAVRYLSDAEGWSAEFTGRAA
Protein
Acireductone dioxygenase: mtnD

Gene
mtnD
Protein
Acireductone dioxygenase
Organism
Rhodopseudomonas palustris (strain TIE-1)
Length
165 amino acids
Function
Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Similarity
Belongs to the acireductone dioxygenase (ARD) family.
Mass
18.058 kDa
Sequence
MATLLFDDGREATAAEIEAIARAHRIVVEHRPVPAALAETLARPLLDDTAAATVLDALPPRPEFPSRDLIVLHPERPDNEQLATKFENWHRHAGDEIRHILDGAGIFGVIVDGQRADLHVGPGDFIVVPAGLEHNFRLTAARRIKAVRYLSDAEGWSAEFTGRAA
Protein
Acireductone dioxygenase: mtnD

Gene
MtnD
Protein
Metallothionein-4
Organism
Drosophila melanogaster
Length
44 amino acids
Function
This protein binds cations of several transition elements. Thought to be involved in metal ion homeostasis (By similarity).
Similarity
Belongs to the metallothionein superfamily. Type 5 family.
Mass
4.545 kDa
Sequence
MGCKACGTNCQCSATKCGDNCACSQQCQCSCKNGPKDKCCSTKN