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queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Length
257 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
27.994 kDa
Sequence
MPVSETTDRQASNGGDGPALPINELFYSLQGEGKLAGTPSVFVRTSGCNLRCWFCDSYHTSWEPTHATMSVDDIIAEVQSYEHADHVVLTGGEPLLHDDAVVLLDRLAALGYHTTVETNGTIHRDAPIDLASVSPKLASSTPTAETDPKGDGEWAARHDARRIDVATLGALADDYDTQLKFVVTDPSDMPEIESLLAEIRTATDTRIGDEDVVLMPEGTTHAELDARRNEVATLAMEHGYRYTPRLHVALWNDAPET
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Length
257 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
28.263 kDa
Sequence
MKSVDHPVDVLPAEHSAETPGDARASESSLLISETFVSRQGEGELTGTESVFIRTSGCNLRCWFCDTPYASWKPEGTRQTIEDLLQLVAKSGVKHVVLTGGEPLIAKGIVSLIDQLRSAGNHVTIETAGTVDPGARCDLLSLSPKLRASTPDAKDHPRLAKMHAERRLPINTMKQLIQSAEATQVKFVVDSADELPEIDEVVRQLEIAADAVYLMPQGISVEQLDAARPWLEPMAISRGYQYCDRMQIRWFGNRRGT
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
255 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
28.638 kDa
Sequence
MSSSSYEAASIKEIFCSVQGEGPYVGVRQAFVRFSGCNLNCNYCDTNFENLGTCDYEIIEGNGIFEKIPNPINVEKLESLLQPFKKLHSVSLTGGEPLLHADFIEKLKLPVPLYLESNMTLPEQARKLRENITYVAGDFKLPEALREIRPETRDMHVENTIKCFSLLKKNKLRDCFCKIVVGRDTRPETVVLAAEAIASDVSCIILQPETPVGSAVRTPRFTQASVQTILKLQKTLLELADTRIIPQTHRMWGCL
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
253 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
28.598 kDa
Sequence
MRVIMAEVFNSWQGEGGSVEGSAFGRRQIFVRFAGCDLHCAWCDSREYIDASRVSSWRYEVKPFTGRFEYRPNPASVEEVVEAVLRLDTGDIHSISYTGGEPTLQVKPLMALMERMKELGFDNFLETHGGLPELIRDVAPLTDYASVDIKDESAKATEDWKGLVLREVESIRILKEAGAKTYAKLVVTSETKVENVQWYASLLKGLAPLVIQPREPIEVSQAKLMEFYREAARIMGRKNVGLSFQVHKYLNVL
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
252 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
27.94 kDa
Sequence
MGTGGRGRPTPGLNVYEVFLSLQGEGKFVGEPQAFVRFSGCNLRCAYCDEPASRSSRRRALIRRVSGEVELELPVPCGPEDVVEVLVELEDLEDTFGTVSLTGGEPLVQPWGALKELIERLRERGFRVLLETNASLPDRAPLIDELADVVSADVKLPSHGPNMDDFPDRCLRFLERISAEVYAKVVLVDEECYQHAESALKGLHRLGVEPIYLQPATGSEHDLEDLWELAGLVNADVRVLPQVHKLVDFIPR
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Agrobacterium fabrum (strain C58 / ATCC 33970)
Length
251 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
27.452 kDa
Sequence
MTEAARNIAARETTVRISEIFGPTIQGEGPLIGLPTVFVRTGGCDYRCSWCDTLHAVDSEYRDTWKPMSVEAIWQEVLGLSGGMPLTVSLSGGNPAIQPLGTLIAKGQGEGYRFALETQGSIAKDWFADLDHLVLSPKPPSSGMETDWQAFEDCLAAAGDGPQVALKVVIFDDADYAYAKAASARFPHLPVYLQPGNHTPPPPDDDDARVDIDGVMDRMLWLVEKISEDRWFSARVLPQLHVLLWGNKRGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
250 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
27.879 kDa
Sequence
MSKPGAELEEVFSSVQGEGMLIGLRQVFIRFRGCNLTCDYCDTPAGTPAEPCRIEQTPGRRDFVPADNPVSLDRVAALVEGWQRGWPGVHDSISITGGEPLLRHDILMQWLPVLREHLPVYLETNGVMHAALGLVINHVDIIGMDIKIPSTSGCTDLWDDHRQFLEIANTRRAFIKIVVGEETEDWEITRASEIIAGVNRDIPLILQPVTRAGDTLGIKPVKALELQELACRYLAEVRIIPQTHRFMGQL
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Length
247 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
28.733 kDa
Sequence
MQLVESFLSIQGEGKYNGKLAIFMRFAGCNFNCLGFNVKISKNDKTLIGCDTIRAVFTKDFKESYETLNANELLKRVIKLKKDFDPIVVITGGEPLIHYENPEFIEFIQMLLKNKFEIHFESNGSIEIDFDRYPFYKECIFALSVKLQNSGIKKDKRLNFKALKAFKNYAKDSFYKFVLDANTLDNSFLEINEILKEAPNQIFCMPMGENEQNLKKNAQKIAEFCIKNGYNYSDRIHIRLWNDKEGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
247 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
27.374 kDa
Sequence
MILMRAPIVEVFSSIQGEGLLVGRRQIFVRFAGCNLNCSYCDTPESRDPSAGRLFTAPELTEIIEGLITPDFHSISITGGEPLLYPDFITELLEESPHRTLLETNGSLPSNAERIAHLFDYASVDIKIAEHFSDNLRSGTTESDISSPGDLIDREIQVINILISRGVNTYCKVVVMPTTGAGYIGALAERLLECVDEPERLPLVIQPCSPPEQWAQNTPRLLEMSQEAGKYMDVYVIPQMHRALGLR
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Bacillus subtilis (strain 168)
Length
243 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
27.122 kDa
Sequence
MAKGIPVLEIFGPTIQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIRWMTAEEIFAELKDIGGDAFSHVTISGGNPALLKQLDAFIELLKENNIRAALETQGTVYQDWFTLIDDLTISPKPPSSKMVTNFQKLDHILTSLQENDRQHAVSLKVVIFNDEDLEFAKTVHKRYPGIPFYLQVGNDDVHTTDDQSLIAHLLGKYEALVDKVAVDAELNLVRVLPQLHTLLWGNKRGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
243 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
28.28 kDa
Sequence
MIREIFNSIMGEGKYIGRRFIFVRFAGCPLNCVYCDEESKGYFNRVEKIPGSGEFETLQKMEIEDIINAIDKLKTPDLFAVSFTGGEPLLYHKQIKEIAEILKDKGYRTFLESNGMFPERIFYFDIASIDIKLKEHFEYIKDEDYEKLYKNELKTIKKLYNLNSDIYAKVVIMEETNIEDVKIIAKDLSDIGNITLCIQPVTPHGNIKSPSQRKLFEIMEACGEYLKDNVMLTIQMHKYLGML
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
238 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
26.872 kDa
Sequence
MSKIPVLEIFGPTIQGEGMVVGQKTMFIRTAGCDYSCAWCDSAFTWDGSAKDQIRQMTPEDIWDELVAIGGENFSHVTISGGNPALLKNIEFLLSILKENGMRTAIETQGSKWQDWLLQIDEITISPKPPSSTMKTDFQRLDAIIQKLAGKDISLKVVVFDDHDFEYAVKMHERYPKVPFFLQVGNDDTKTVDDAMLIKKLLDKYEWLIDKAVNCKEMNDAKVLPQLHALVWGNKRGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Length
237 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
26.674 kDa
Sequence
MDNLKTSVHEIYLSLSGEGISTGIPTIFVRMAGCSLRCGMTVGRKLWCDTPYALSPKAGEEMSVNQVLDKIQELSAVNIQILLTGGEPLEGRNREFSITLGNEIFRIRNSSGFYPRPRVETNGAESIEGMDQFVFTLDYKLPGSGMEDRMNLKNLEIYKERKNPLDEIKFVIRDKNDFERCLEIIEKHALVGNLLASPVQGELSPEILAEWIKYSLGSGLRLSIQTHKYIWGDQRGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
Length
235 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
26.499 kDa
Sequence
MSRSARRKTSALNTVLRVVEVFASIQGEGPFTGTYSVFVRLAGCNLRCPFCDTRYAWSLEAGKPLGVEELVEEIARYEPSLVVITGGEPLLQRHPLNSLVEGLESLGLRVQLETNGILPAPARDEQLWRVYHVVSPKDVPVRVPGAKLHPSWVDYARATGRAWFKFLVANEQHVREVAEYVAKLGIPRSRVYIMPLTPEKLDMKELLELHSRIASLAVKWRLNFSPRLHLLVQLP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Length
235 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.641 kDa
Sequence
MFGRNPARGPDPGDGESLWIQEVFYTLQGEGPFSGQPSVFVRTAGCNLRCAWCDTDFESSAWKPPLPELLAVIDSRRPRVCDLVVLTGGEPLRQEVGPLVRALLARGLRVQIETNGTLWRDLPFGPGLSIVCSPKTRTLDPQLVPRIDAFKYVIAAGETDPTDGLPALSTQHPGRAERLFRPPPGVPVFVMPRDDHGTPARPGRGEDDNLAEAAASALRFGYRLCVQVHKILKIA
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Length
234 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.117 kDa
Sequence
MPLNCDTKTAGEISSSIPSGSGSHQPAAQSSGMKIAEIFTSLQGEGLTSGYPTIFIRLAGCNLSCSYCDTPASRQGGMDMNVSEVVAGALLQKPHYVCITGGEPLLQKDEVAELARQLIKAGKMVSIETNGTVPFDDLPSDISICMDVKCPSSGEFSNINLLSDLKSTDSVKFVVGTDDDLQYAEKVIMSHPTKAEIFISPIYGTDYQRIASYILSRNLPARMQLQLHKFIGLP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Rickettsia prowazekii (strain Madrid E)
Length
234 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
26.247 kDa
Sequence
MNQRINSYKMFGHNPKRSILSGDGTKLEVQSIFKTIQGEGIFVGYPSIFIRLGGCNLACNFCDTEFEDFKLIDIDQILNKVKNLSLNSKNAKTINLVVITGGEPMRQPIGLLCQKLLDQDFKVQIETNGTLYRSLPKEVFIVCSPKVGKTGYNKIREDLLPQISAVKFIISKNIVEYSIIPEVGQSAYDIPVFVQSMDQNDKRLNNENNELAVKLALESGARLSLQTHKFLGIE
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Koribacter versatilis (strain Ellin345)
Length
226 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.356 kDa
Sequence
MQITEIYRSLQGESSYTGIPCIFVRLTACNLRCAWCDSEYTFKGGRKMSEDEIFAEVQKLAPGGLVEITGGEPLLQERELVPFMERLVASGYKVLIETSGERPLANVPQDVVKIVDVKCPASGEGGSFRIENLDALTPHDEIKFVISDRADYEFAREFTRQHGLENKVSSVIFSPAFRKDARGTRDASHCLVDPQDLANWVLEDQLDVRLGLQTHKFIWTPETKGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
225 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.873 kDa
Sequence
MRANLIEIFESIQGEGFYIGVRQLFVRFAGCNLNCYYCDTPKTSENCLDLTANRTLKNPVSAEYVQGRIDSSKVHSVCFTGGEPMLQAEFIASLSKTHPFYLESNMTLPEKAKKLKFCDYVAGDLKVREAGLKNYDEVFQKTVKCFKVLRNTRRRKTFCKIVLPDKFDADEVLNSAYEIKNYVFGFVLQPVFGSRVEKILKLQKRMIDFADTRVIPQVHKYLGVR
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Length
225 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.318 kDa
Sequence
MSTCLPIVERFHSLQGEGLHFGKSAFFIRLGGCKVGCPWCDTKESWSIATHQEATVEELSKEAAIAQSQGAAILVITGGEPLHHNLNALCKTIQDFTSHNSRETMPIHLETSGVDEITGLINWITLSPKRHALPKKSLLRACDEIKVVIHQKEDLLFAEEMANQSIKERQISKKTSDENHKISQPHLFLQPGWNSKEGTQLTIEYIKSHPQWRLSLQTHKWLGVL
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Escherichia coli O157:H7
Length
223 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.03 kDa
Sequence
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Escherichia coli (strain K12)
Length
223 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.03 kDa
Sequence
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Shigella flexneri
Length
223 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.03 kDa
Sequence
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
222 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
24.359 kDa
Sequence
MSATPRVRVLEIFASLQGEGINLGRPAVFVRLAGCPIRCIYCDTKYSWDFNAGVEMGVEEIVAKALALSVVGHVVVTGGEPLIWQRRGLEELACALRALGSVEVETSGAYPPTPELDRCVDFYDVSPKLSNAGVKAPFSPFYASSPKAWFKFVVSNADDVEEVERFVVAYGIPRGRVFLMPMAESPEEHGEALRRIWDAAVRGGFRVTPRLHIMAWGNARGK
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Length
221 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.176 kDa
Sequence
MNYKVVEKFVSINGEGLKSGQLSVFIRFAGCNLNCNYCDTKWANEKDVKYTLMTEKEILSYIKETGVKNVTLTGGEPLLQDGIVELLNLLSLDSTLRVEIETNGSVSLENFLNFKNAPSFTMDYKLPDSSMENFMKTSNFKFLNKKDVIKFVVSSLKDLKKAMDIITEFNLSKKTNIYISPVFGRISPETIVDFMKDNKLNDVTLQIQIHKIIWNPNKRGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
220 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
24.257 kDa
Sequence
MSTEAPLNISEIFYSIQGESSFAGWPCAFVRLAGCGHGCRYCDTTYAEEPGTAMTIDEIMHRVLAFDAPCVEVTGGEPLLQSGTFGLLSALCDRHPVVLLETGGFLPVDRVDPRVHAIIDIKAPSSGVMEHNCAANFTLALNEPERFEFKIVVASEADYLWAKSYIAGHGILGKCSIIFGPVFGQLEPRLLAEWMLRDRLPVRMQLQLHKYIWNPDARGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Aquifex aeolicus (strain VF5)
Length
219 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.336 kDa
Sequence
MLRNKVRKTDTLIALNEVYESIQGEGLLVGLPSVFIRLQGCNLRCPWCDQPEALSFSGRKVKLSSLINELKKFTAKHIVITGGEPFAHRELPFIVEFLLSEGYSVQIETNGTLWVEEMEKFAEGIHITCSPKGVAKYYVHPKILKYAKELKFVVDKEFSKEVLKKEEFERFLREGKVVLQPESNRKEMMEKALKIQKELLKECYTVRVIPQVHKCFDLK
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
219 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
25.989 kDa
Sequence
MYYPINEIFQTIQGEGYYTGTPSIFIRLQGCPVHCKWCDTKYTWKCNNEDQISYEKIIMKKKSNRKWSYMNVKEIILIIKIKKWTAKHIVITGGEPCLYNLLEITKELEKEDYKCQIETSGTELIKCSLNTWITLSPKINKKTLKTSILRSNEIKYPVLKKEDLFYLNSILKKIKNKKHNLIFLQPISQNEEALNICIKTCIIKNWRLSVQIHKYLKIR
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Length
216 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.535 kDa
Sequence
MTYRVKEIFHTLQGEGMRAGRAAVFCRFSGCNLWTGWAQDRPAAVCPFCDTDFVGTDGPGGGVFEDAATLAAAILAAFPYKTGEGYRPYVVFTGGEPALQLDRPLIDILHAHGCEVAIETNGTVRLPEGIDWVTVSPKAGTRLAVTSGDELKLVWPQQGICPESYESLAFTYLLMQPRDGLGDAGRGDAESEAVRWCLAHPRWRLCLQTHKYLGIP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Length
214 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.573 kDa
Sequence
MNAASTVVKPVSAQSIPVQETFGPTIQGEGYWAGAVVDFIRLYGCPVGCPWCDTGYADGGPQLPRAVRTFSDLILELKSPRVVISGGEPFIHAALPALVEAIGRTGRAVAIETSGAFWQPVPDWAWVTLSPKEHVSPRHPVNPQMWRRANEVKIVIAGGAELDVYRRFLPPGVPVSLQPEWEARERTLPLTLELLKAHPRYRLSVQLHKYLQVP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
212 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.71 kDa
Sequence
MKKINVAPENPQYRIVEIFESLQGEGWNTGMPAVFVRLGKCNLACGWCDTDYLTFGMMGLSDILGRLKTYAARNIIITGGEPTIQPHLDMLLDTLKAEGYFLCLETNGLNPAPPQIDYVATSPKACYAAKYENSCIETADEVRIVADGDVLAFCENMERKIRAHHYYLSPCEQDGAMNIYDTIRQIGILNSRPDASVHWQLSVQTHKWAGIE
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
211 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
24.337 kDa
Sequence
MLMEKYHDFEPNFNIVEIFESLQGEGFNTGMPSVFVRFGKCNLDCPWCDTPYNNFKRWSVSQILEKVRSFSSKNIIITGGEPTIVPKIEYLLEQFKSDGYFLAIETNGLKAIPAQIDYIATSPKSLYAHKYEKRCIPFANEVRIVMDSNMPSFCELIEQKIKAKNYYLSPCEIDGKMNLLETITLLGQLNQRSNKPKWQLSLQTHKLIGIE
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Length
210 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
22.58 kDa
Sequence
MAYSVKELFKTLQGEGAQAGRAAVFCRFAGCNLWTGRESDRAGAACTFCDTDFVGTDGQGGGKFADAAGLADAIAACWGEHPADRYVVFTGGEPLLQLDEALLQAVHAQGFTVAIETNGTLPPPPGIDWICVSPKGRAPVVVERGHELKLVFPQADARPEAFAHLAFEHFFLQPMDGPARAAHTTQAVQYCLDHPQWRLSLQTHKYIGIP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Length
210 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
22.82 kDa
Sequence
MSYAVKEIFLTLQGEGAHAGRASVFCRFAGCNLWSGREADRQDATCKFCDTDFVGTDGTLGGRYASAVELADTIAAQWTASNDNRYVVLTGGEPLLQVDDALIDALHARGFEIGVETNGTIAAPDGLDWICVSPKGGSELVLRRGHELKLVYPQALAAPETFEGLAFERFSLQPMDGPEVAENTARAIDYCLRHPQWRLSVQTHKSLGIR
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Length
210 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.148 kDa
Sequence
MTYAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWPAGEAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRHPQWRLSMQTHKYLNIP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Caulobacter vibrioides (strain ATCC 19089 / CB15)
Length
210 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
22.668 kDa
Sequence
MTYSVKEIFLTLQGEGGQAGKAAVFCRFSGCNLWSGREQDRAKAVCTFCDTDFVGTDGENGGKFATAEDLAAAVEAQWTGGPDDRLVVCTGGEPFLQLDDAAIAALHARGFQIAVETNGTITAPAGVDWICVSPKADAPVVQTSGQELKLVFPQEKAMPERFAALDFERFYLQPMDGPDRDANTQLAVAYCLSHPQWRLSVQTHKYLGLP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Length
210 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.981 kDa
Sequence
MLTKEIQIAVEKGEMLPLMEEFYTIQGEGYHTGTAAYFIRIGGCDVGCHWCDVKESWNAALHPPTKTDVIVENATKYAKTIVVTGGEPLTWDMTVLTQRLKAENLQVHIETSGAYPVTGAWDWFCLSPKKNKLPVAEAYEIAHELKVIIYNKHDFIFAEEQAAKVNKNAILFLQSEWSKKEEMTPFIVDYVMNNPKWRVSLQTHKYLNIP
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Length
209 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.642 kDa
Sequence
MLITEIFHSIQGEGPYAGLPMLFVRTNVCNIRCEWCDTKYSFYGGKEIPLSELLGIVKEAKEGWVCFTGGEPLVQRDALAFVKSVVDMGKNVLIETNGTISIRNFVFSDRIFIDMDVKPPSAKVTKGFLMDNLRYLRKQDYLKIVIKDDTDLDFAIDFVDRYGEGLSFVFQPAWGSDIRRIADRIVGTGYNVRVLPQIHKIIYGDVPGV
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
208 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
23.508 kDa
Sequence
MSMGPISELLTVSYPIAETFHSLQGEGAWAGGNAFFIRLGGCDVHCPWCDQKETWPTQHHPRQTVTELVQQAVTAKPSFVVITGGEPLMHDLQPLCKTLKNQGLRLHLETSGAYPLTGQFDWITLSPKPYKLPQAAIYPLANELKVIISQDEDFDWAEMEARKISPGTPLYLQAEWETEAMNEKIFAYILTHSQWRLSLQTHKYLGVR
Protein
7-carboxy-7-deazaguanine synthase: queE

Gene
queE
Protein
7-carboxy-7-deazaguanine synthase
Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Length
182 amino acids
Function
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Similarity
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Mass
20.541 kDa
Sequence
MMRKINEIFYSLQGEGYHTGTPAVFIRFSGCNLKCSFCDTQHEAGTLMTDDEIIAEVSKYPAVTVILTGGEPSLWIDDALIDRLHEAGKYVCIETNGTRPLPESIDWVTCSPKQGVKLGITRMDEVKVVYEGQDISIYELLPAEHFFLQPCSCNNTALTVDCVMRHPKWRLSLQTHKLIDIR
Protein
7-carboxy-7-deazaguanine synthase: queE