Description
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Family
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Species
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Sequence
MIREIFNSIMGEGKYIGRRFIFVRFAGCPLNCVYCDEESKGYFNRVEKIPGSGEFETLQKMEIEDIINAIDKLKTPDLFAVSFTGGEPLLYHKQIKEIAEILKDKGYRTFLESNGMFPERIFYFDIASIDIKLKEHFEYIKDEDYEKLYKNELKTIKKLYNLNSDIYAKVVIMEETNIEDVKIIAKDLSDIGNITLCIQPVTPHGNIKSPSQRKLFEIMEACGEYLKDNVMLTIQMHKYLGML
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service