Description
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
Family
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Species
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Sequence
MSATPRVRVLEIFASLQGEGINLGRPAVFVRLAGCPIRCIYCDTKYSWDFNAGVEMGVEEIVAKALALSVVGHVVVTGGEPLIWQRRGLEELACALRALGSVEVETSGAYPPTPELDRCVDFYDVSPKLSNAGVKAPFSPFYASSPKAWFKFVVSNADDVEEVERFVVAYGIPRGRVFLMPMAESPEEHGEALRRIWDAAVRGGFRVTPRLHIMAWGNARGK
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service