Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.

Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.

253 amino acids

MRVIMAEVFNSWQGEGGSVEGSAFGRRQIFVRFAGCDLHCAWCDSREYIDASRVSSWRYEVKPFTGRFEYRPNPASVEEVVEAVLRLDTGDIHSISYTGGEPTLQVKPLMALMERMKELGFDNFLETHGGLPELIRDVAPLTDYASVDIKDESAKATEDWKGLVLREVESIRILKEAGAKTYAKLVVTSETKVENVQWYASLLKGLAPLVIQPREPIEVSQAKLMEFYREAARIMGRKNVGLSFQVHKYLNVL

28.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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