mutM

Formamidopyrimidine-DNA glycosylase

365 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

39.011 kDa

MPELPEVETIACGLRPALSGRRIVGVTVHNPGTLEGPLCTPAAFTEAVQGQRIADVGRRGKLLLVAFASLPPVGHAGQPRPEGLSSSTVRDFLVTHGFHAAGCATSVHACAPLLADGQQTRGRLAGHGDGMDGTSRTGSTLPGTGGTENSDAVAVADDDTVLGLAFHLKMTGRLFIHPPATPAGIHTRVVFDLEGGTRLFFDDARKFGYVRCITRRSLALWPFWRDLGPEPLETEARGFAARLARRRGRIKALLLDQKVVAGVGNIYADESLFRAGIRPDTQAHTLTPERLFALHGHLQDVLRESIAECGSSIRDYRDAHGDAGAFQNSFRVYGRGGQPCRHCGTTLATAQVAGRTTVFCPQCQR

mutM

Formamidopyrimidine-DNA glycosylase

309 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

34.59 kDa

MPELPEVETTKTSLAPLLGQKVTNVQVFQPKLRWSIPDNLADLVDYTLDSVERRAKYLILNFIPLADDGISSTVQPRNLQPRQLLVHLGMSGSLQQHNHASDKRKHDHLIMSFIGADSTQTQLHYYDPRRFGSILWLEEYGDKLLNHLGPEPLSDAFTADYLYHLIQRSRQSIQTQNSKSIKKQPIKRAIKSVIMEQQAVVGVGNIYATESLYLSGIHPATPANEVSYAQIVILVAHIKTILQKAIKLGGSTLRDFTVADGQTGYFQQTLNVYGRQGNACPHCESTLENIKLNGRASVYCPLCQPIISM

mutM

Formamidopyrimidine-DNA glycosylase

308 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.227 kDa

MPELPEVEVVRRGVARWVVGRTVSSARFLHPRVTRRHVAGPDDAGARTRGLVVADAVRRGKYLWLPLATPDGRAEEAMVVHLGMSGQLLVEAADAPEEKHLRAVWTFDDGGEDLRFVDQRTFGGIAVVPLVATPDGGPGGLGETPDGSWSGSMPAPVAHIARDPLDPAFDDAVFARRLRERTTGLKRALLDQTLVSGVGNIYADEALWRAKLHYARPTRSVTPAQAAALLAGLREVMTAALDAGGTSFDSLYVNVNGASGYFDRSLAVYGQEGRPCPRCGALVRRDAFMNRSSFSCPVCQPVPRSPHW

mutM

Formamidopyrimidine-DNA glycosylase

306 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.448 kDa

MPELPEVETVKRGLAPTMEGALLVRAELRRPDLRFPFPENFEDAVAGRRIVALSRRAKYLTIELEGGDVIIAHLGMSGSFRIEFDGPGEGRIKESADPAVPGDFHRPRSKDEKHDHVVFHLDASCGPARVIYNDPRRFGFMALARREALAEHVFLRGLGEEPTGNALDAAYLAARFSGKAQPLKAALLDQRTIAGLGNIYVCEALWRSGLSPKRAAGTLVDKRARPKQALVQLTDAIRAVIADAIAAGGSSLKDHIQADGSLGYFQHSFSVYDREGEACRTSGCRGTVERIVQAGRSTFYCPHCQK

mutM

Formamidopyrimidine-DNA glycosylase

305 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.684 kDa

MPELPEVETVRRTLCPRVVGRRIRRVEILTPRQIYHPDPATFAADLEGAVFDDIERRGKYLLFRLGPRILVAHLRMSGHLYVCGPEAPRPRHLHVVFHLDDGGELRYADQRKFGGFHLLGPGGEGMPPGLANLGPEPLSPEFTPQVLAERLAGRHTSIKAALLNQALVAGLGNIYADEALFCARIHPAREAGSLTPAEVERLHGCIRRVLLRAVERRGTTFSLYRDGEGNEGDMYDELQVFDRAGEPCPVCGTPIRKVAVAQRGTHFCPRCQPVPEGVALSPRRARPGRRGNSVRVAAEPPGTYE

mutM

Formamidopyrimidine-DNA glycosylase

301 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.79 kDa

MPELPEVETVKRGLAPAMEGARVAKLELRRGDLRFPFPDAFADRVSGRTIVSLGRRAKYLLVDLDDGNTLISHLGMSGSFRIEEGRIEEGAGAATPGEFHHARSKDEKHDHVVFHLESPAGPRRVVYNDPRRFGFMDMVGRADLAAHPFFRDLGPEPTGNELGAAYLAERFRHKAQPLKSALLDQKNIAGLGNIYVCEALWRAHLSPIRAAGTLATAGGRPKEQLNLLVASIRDVIADAITAGGSSLRDHIQTDGSLGYFQHSFSVYDREGQACRTPGCGGTVARIVQAGRSTFYCATCQK

mutM

Formamidopyrimidine-DNA glycosylase

301 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.696 kDa

MPELPEVETVKRGLAPTMEGALLVRAELRRPDLRFPFPENFANAVAGRRIIALSRRAKYLMIELEGGDVIIAHLGMSGSFRIEKGPIEAGADPATPGAFHHPRGKDEKHDHVVFHLDGGSGPARVIYNDPRRFGFMDLARRSALADHVFLRGLGEEPTGNALDAAYLATRFAGKIQPLKAALLDQRTIAGLGNIYVCEALWRSGLSPKRSAGTLVDKRGRPKQALIALTERIRAVIADAIAAGGSSLKDHIQADGSLGYFQHSFSVYDREGEACRTPGCHGTVARIVQAGRSTFYCPHCQK

mutM

Formamidopyrimidine-DNA glycosylase

300 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.875 kDa

MPELPEVEIVKQGLNQLTLNKRILGGEVLLERTLAYPISVADFLRGLEGKAIAQWHRQGKYLLAQLYKWGKKNSKLQEYENEDGWLGVHLRMTGQLLWVNPEESLHKHTRVRLFFGHNSSGDKDSSNYELRFVDQRTFGKMWGVPPGKEISKVITGLQQLGLEPFSPEFSPKYLNKKLYKRHRPIKTALLDQTTIAGLGNIYADEALFLSGIRPTTICKDLTEKQIEQLHLAILKVLQTAINAGGTTFSNFLNVKGVNGNYGGVAWVYSRAGQPCRICNTPLEKIKLAGRSTHFCPQCQK

mutM

Formamidopyrimidine-DNA glycosylase

299 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.407 kDa

MPELPEVETVRRGLAPAMVGARVARVTLRRPNLRFPFPERFAERLEGTTVLELARRAKYLTAHLDSGESLILHLGMSGRFDVRLPDGSNLSPGDFYLEGALGTPKHDHVVMAFANGATVTYNDARRFGFMDLVATRDLETCRHFASMGVEPLSDALDAPLLARLFARKITPLKAALLDQRLIAGLGNIYVCEALHRSGLHPALPAGALAKPDGSPAPKAKTLVKEIKAVLTEAVAAGGSTLRDYARPDGERGAFQHGFRVYDRVGHACPTKGCTGRVGRIVQGGRSTFFCETCQVLPVR

mutM

Formamidopyrimidine-DNA glycosylase

299 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.407 kDa

MPELPEVETVRRGLAPAMVGARVARVTLRRPNLRFPFPERFAERLEGTTVLELARRAKYLTAHLDSGESLILHLGMSGRFDVRLPDGSNLSPGDFYLEGALGTPKHDHVVMAFANGATVTYNDARRFGFMDLVATRDLETCRHFASMGVEPLSDALDAPLLARLFARKITPLKAALLDQRLIAGLGNIYVCEALHRSGLHPALPAGALAKPDGSPAPKAKTLVKEIKAVLTEAVAAGGSTLRDYARPDGERGAFQHGFRVYDRVGHACPTKGCTGRVGRIVQGGRSTFFCETCQVLPVR

mutM

Formamidopyrimidine-DNA glycosylase

299 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.464 kDa

MPELPEVETVRRGLAPAMVGARVARVTLRRPNLRFPFPERFAERLEGTTVLELARRAKYLTAHLDSGESLILHLGMSGRFDVRLPDGSNLSPGDFYLEGALGTPKHDHVVMAFANGATVTYNDARRFGFMDLVATRDLETCRHFASMGVEPLSDALDAPRLARLFARKITPLKAALLDQRLIAGLGNIYVCEALHRSGLHPALPAGALAKPDGSPAPKAKTLVKEIKAVLTEAVAAGGSTLRDYARPDGERGAFQHGFRVYDRVGHACPTKGCTGRIGRIVQGGRSTFFCETCQVLPVR

mutM

Formamidopyrimidine-DNA glycosylase

298 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.661 kDa

MPELPEVETVRRGLAPAMEGARVRKLHLGRPDLRFPFPADFAGLIEGKTIISLGRRAKYLLIELEDGLTIVSHLGMSGSFRIEAEKGEGGEAPGAFHYARSKDGKHDHVVFHLDKGEERVCVIYNDPRRFGFMHLVERNKLDLYPAFAELGPEPTGNALSADYLASRFEGKSQPLKSTLLDQKIIAGLGNIYVCEALWRAHLSPLRAAGTLVTTRGKPKAQLIDLTEKIRDVIADAIAAGGSSLRDHIQTDGTLGYFQHSFSVYDQEGQPCRTPGCGGTVERVVQAGRSTFYCAACQK

mutM

Formamidopyrimidine-DNA glycosylase

297 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.944 kDa

MPELPEVETVKRGLAPSMEGRRLTRLELRRTDLRFPLPVDFAARTQGRLIVSLSRRAKYLLIDLDDGVSIVSHLGMSGSYRIEAANETGLPGQFHMARSRDEKHDHVIFHLSGPEGDPLRVIYNDPRRFGFMDMVERRHMDRHAAFAGLGPEPVGNALDADYLAFRFKGKAQPLKTALLDQKVIAGLGNIYVCEALWRAHLSPETPARALVNAEGKPVAALEDLTQAIRTVIAEAIEAGGSSLRDHIQADGSLGYFQHSFNVYDREGEACRTPGCTGTVERMTQAGRSTFHCPQCQR

mutM

Formamidopyrimidine-DNA glycosylase

297 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.476 kDa

MPELPEVEVVRAGLAPAVTGATILGVEVFELRSLKRHDPLAGSFESLLTGRSMQTPARRGKFLWIPLDSSPRSAIVAHLGMSGQILLRDPGTVENGLLRIRLYIEHPEHGELWVHFVDQRLFGSMAVDALVPTVDGAPAGLGTDEALLPAQVSHIARDPLDPVFDDAAFAAVLARRRSGIKRVLLDQTLISGIGNIYADESLWAARIHYDHPATALSRPRVRTLLAELRRVLGRALAEGGTSFDAQYVNVNGASGYFSRSLHVYGRQGQPCDRCGTAIVRESFMNRGSHFCPRCQRM

mutM

Formamidopyrimidine-DNA glycosylase

297 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.476 kDa

MPELPEVEVVRAGLAPAVTGATILGVEVFELRSLKRHDPLAGSFESLLTGRSMQTPARRGKFLWIPLDSSPRSAIVAHLGMSGQILLRDPGTVENGLLRIRLYIEHPEHGELWVHFVDQRLFGSMAVDALVPTVDGAPAGLGTDEALLPAQVSHIARDPLDPVFDDAAFAAVLARRRSGIKRVLLDQTLISGIGNIYADESLWAARIHYDHPATALSRPRVRTLLAELRRVLGRALAEGGTSFDAQYVNVNGASGYFSRSLHVYGRQGQPCDRCGTAIVRESFMNRGSHFCPRCQRM

mutM

Formamidopyrimidine-DNA glycosylase

297 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.54 kDa

MPELPEVEVTRRGLLPHVVGRRIADVIVRHRGLRWPVEPELEARLTGRIIGRIERRGKYLLLECLPPADATRAGTGEDAAPGWLLVHLGMTGTLRVYPAPPAPGAHDHLDLLLAAGPDTAEAEPVVLRFRDPRRFGAILWTPLAESDLPGHPLLSRLGIEPFDPRFDGAWLHRGMRGRSMAIKQALLAGDVVVGVGNIYCSESLFRAGIRPTTQAGRLSLARCEKLAVAVRETLAEAIARGGSTLRDFVGSDGSSGYFQLDCFVYDRAGEPCRICGTPIRQILQGQRSTFYCPHCQH

mutM

Formamidopyrimidine-DNA glycosylase

297 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.238 kDa

MPELPEVETVRRGLEPALVGACFSHVHLARPDLRFPLPERFAARLTGQRVEALSRRAKYLVADLSSGEALIMHLGMSGRFDVVLPDGRQVSPGDFYLEGAGARAKHDHVSFALSNGARVTYNDVRRFGFMDLVPAAELATCRHFAGMGIEPLGNELSGEAVARLFRGRRTPLKAALLDQRLIAGLGNIYVCEALHRARLHPETPAGALADAAGRPTKAARLLAEVIRDVLTEAVAAGGSTLRDYVHTDGTKGAFQHAFRVYDREGLACTARGCRGVVRRVVQSGRSTFFCEVCQPAR

mutM

Formamidopyrimidine-DNA glycosylase

297 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.46 kDa

MPELPEVETVRRGLEPALVGARFTTVHLARPDLRFPLPARFAARLTGQRVEALSRRAKYLVADLSSGDALIMHLGMSGRFDVVFPDGRQLSPGEFYLEGAPGQAKHDHVVFALSNGARVTYNDVRRFGFMDLVRRAELETCRHFAGMGIEPLGSDLSGEAVARLFRGRRTPLKAALLDQRLIAGLGNIYVCEALHRARLHPEAAAGTLADAAGRPTRAAARLAQVIRDVLTEAVAAGGSTLRDYAHTDGTQGAFQHRFRVYDREGLACTARGCRGRVRRIVQAGRSTFYCETCQPAP

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.191 kDa

MPELPEVETVKRGLAPAMEGARVARLELRRQDLRFPFPEALADRVSGRTIVGLGRRAKYLLVDLDDGNTLVSHLGMSGSFRIEEGAASAMPGEFHHARTKDEKHDHVVFHLEGQGGPRRVVYNDPRRFGFMDMVRRADLAAHPFFRDLGPEPTGNDLGAAYLAERFRDKAQPLKSALLDQKNIAGLGNIYVCEALWRSHLSPIRAAGTLVTPGGKPKEKLGLLVASIRDVIADAIAAGGSSLRDHIQTDGSLGYFQHSFSVYDREGQACGTPGCGGTVARIVQAGRSTFYCAACQK

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.208 kDa

MPELPEVETVKRGLAPAMEGARVTRLELRRRDLRFPFPDALAERVSGRTIVGLGRRAKYLLVDLDDGNTLISHLGMSGSFRIEEGAASAMPGEFHHARSKDEKHDHVVFHLEGGGGPRRVVYNDPRRFGFMDIVGRADLSAHPFFRDLGPEPTGNELGATYLAERFRDKAQPLKSALLDQKNIAGLGNIYVCEALWRSHLSPIRAAGTLVTSGGRPKQQLDLLVASIREVIADAIAAGGSSLRDHIRADGSLGYFQHSFSVYDREGQACGTPGCGGTVARIVQAGRSTFYCAACQK

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.322 kDa

MPELPEVETVKRGLTPAMEGTRVTRLELRRGDLRFPFPDAFADRVSGRTIVGLGRRAKYLLVDLDDGNTLISHLGMSGSFRIEEGAASGVPGEFHHARSKDEKHDHVVFHLQAASGLRRVVYNDPRRFGFMDMVGRADLATHPFFRDLGPEPTGNELSAAYLAERFRDKAQPLKSALLDQKNIAGLGNIYVCEALWRSHLSPIRAAGTLVTAGGRPKAQLDLLVASIRDVIADAIAAGGSSLRDHIQTDGSLGYFQHSFSVYDRESQACRTPGCGGTVARIVQAGRSTFYCATCQK

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.367 kDa

MPELPEVETVRRGLQPVLEGARLTRVEARRPDLRFPFPERFSERLTGKTITALGRRAKYLTMHVQDGPVLICHLGMSGSFRIETDDDGETPGVFHHERSKSTAHDHVVFDVVAADGARSRVIFNDPRRFGFMLFAEGSPETHPMLAGLGVEPTGNTLDGVLLASLLKGRGSPLKAALLDQKLIAGLGNIYVSEALWRAGLSPLREAGTIARPSKKARQQSERLAEAIRSVISDAIAAGGSSLRDYMHTDGSLGYFQHSFAVYDREGEPCPKPGCGGHIERVVQSGRSTFYCRTCQS

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.192 kDa

MPELPEVETVRRGLAPAMVGARFARVTLRRPNLRFPFPERFAERLEGTTVRELARRAKYLTAHLDSGESLILHLGMSGRFDVRMPDGSNLSPGDFYLEGALGTPKHDHVVMAFANGATVTYNDARRFGFMDLVATRDLETCRHFAAMGVEPLSDALDGAVLARLFARKITPLKAALLDQRLIAGLGNIYVCEALHRSGLHPALPAGALAKPDGAPTPKAKKLVKEIKAVLTEAVAAGGSTLRDYARPDGERGAFQHGFRVYDRVGHACPTKGCTGRIGRIVQGGRSTFFCETCQVR

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.755 kDa

MPELPEVETVRRGLAPALVGARFSRVTLRRANLRFPFPERFAARLEGRTVTGLARRAKYLTAALDSGETLVMHLGMSGRFDVALPDGSNLSPGDFYLEGAQGTPKHDHVVMAMSTGATVTYNDARRFGFMDLVPSAELAACRHFARMGVEPLDGLTGAVIARLFRHKIAPLKAALLDQRLIAGLGNIYVCEALHRARLHPEAPAGSLARPDGRPTPEANALAKAIVQVLEEAVKAGGSTLRDYAHTDGSAGAFQHAFRVYDRVGLPCSRPGCAGAITRIVQANRSTFFCATCQPPG

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.565 kDa

MPELPEVEVVRRGLEKWVVGASFGEVEVLHPRAVRRHAPGAADFAARVSGCGVTEARRRGKYLWLTLDSGEALLAHLGMSGQLLVQPRHAAAERHLRVRLPLTARQGHDPEAPQELRFVDQRTFGHLLVDRLVDDGTGTGLPSVISHIARDPLDPAFDEDAFAAALCRKRTELKRALLDQSLISGIGNIYADEALWMSQLHWATPTEALSRSQVATLLAAVREVMVAALAQGGTSFDSLYVNVNGESGYFARSLNAYGRNDQPCARCGTPIQRETFMNRSSYSCPRCQPRPRHARA

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.641 kDa

MPELPEVEVVRRGLDAHVTGKAITAVRVHHPRAVRRHEAGPADLTARLLGMRITGTGRRGKYLWLTLDGGDEPLARRAESSVALVVHLGMSGQMLLGPIPKEDHLRIAALLDDGTALSFVDQRTFGGWLLADLVTVDGTDVPVPVAHVARDPLDPRFDRDAVVKVLRGKHSEIKRQLLDQTVVSGIGNIYADEALWRAKVNGARLAESLTKPKLAEILDHAADVMRDALGQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRREKFMNRSSFYCPRCQPRPRVRRA

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.719 kDa

MPELPEVEVVRRGLDAHVTGKAITAVRVHHPRAVRRHEAGPADLTARLLGMRITGTGRRGKYLWLTLDDGDEPLARRAESSVALVVHLGMSGQMLLGPIPKEDHLRIAALFDDGTALSFVDQRTFGGWLLADLVTVDGTDVPVPVAHVARDPLDPRFDRDAVVKVLRGKHSEIKRQLLDQTVVSGIGNIYADEALWRAKVNGARLAESLTKPKLAEILDHAADVMRDALGQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPRVRRA

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.719 kDa

MPELPEVEVVRRGLDAHVTGKAITAVRVHHPRAVRRHEAGPADLTARLLGMRITGTGRRGKYLWLTLDDGDEPLARRAESSVALVVHLGMSGQMLLGPIPKEDHLRIAALFDDGTALSFVDQRTFGGWLLADLVTVDGTDVPVPVAHVARDPLDPRFDRDAVVKVLRGKHSEIKRQLLDQTVVSGIGNIYADEALWRAKVNGARLAESLTKPKLAEILDHAADVMRDALGQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPRVRRA

mutM

Formamidopyrimidine-DNA glycosylase

296 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.144 kDa

MPELPEVETVKRGLAPAIEGALLVRAELRRPDLRFPFPENFAAAVSGRRILALSRRAKYLMIDLEGGDVIVAHLGMSGSFRIEAGAQPAAPGEFHHPRGKDEKHDHVIFHLDGGSGQMRVIYNDPRRFGFMDLARRDTIAEHAYFRDLGEEPTGNALDAAYLAARLAGKSQPLKTALLDQRTIAGLGNIYVCEALWRSGLSPNRAAGTLVDKRGRPKQALLALVEAIRAVIADAIAAGGSSLKDHIQADGSLGYFQHAFSVYDRAGEACRKPGCDGTVTRIVQAGRSTFHCPRCQK

mutM

Formamidopyrimidine-DNA glycosylase

295 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.348 kDa

MPELPEVEVVRRGVAAHVVGRTVSEVEVLHPRSVRRHVPGPDDFATRLAGRCLTAARRRGKYMWLELGGGPEEVDAGEAVLAHLGMSGQLLVQPDEAPDETHLRVRFRFDDGGPQLRFVDQRTFGGLSLTELVSVDGVAVPEPVAHIAPDPLEPVFDLEAAVARMRKRRTGVKRALLDQTLVSGIGNIYADEALWRAKLHWARPTANLTRPQARTLLVAAVEVMQAALTAGGTSFDDLYVNVNGESGYFDRSLAVYGQAGLPCPRCGTPVRRDAFMNRSSYSCPRCQPTPRNPHY

mutM

Formamidopyrimidine-DNA glycosylase

294 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.054 kDa

MPELPEVEVVRRGLAEHVAGRVVGAVTITHPRSVRRHLAGSADLAARMTGRRVRAAQRRGKYLWLTFDEPGAADETALDAALVVHLGMSGQMLVQPAAAPVEKHAHIRAALDDGSELRFVDQRTFGGWALAPLAEVDGSLVPEPVAHIARDPLDPRFDAESVVAAIRAKNSEIKRVLLDQTVVSGIGNIYADESLWRAGINGNRLASGLTRPAVRRLLAEVRAVMLEALAAGGTSFDALYVNVNGQSGYFERALAVYGRQDEPCRRCGAPIVREKFMNRSSYSCPRCQPRPRRR

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.966 kDa

MPELPEVETVRRGLLPVLQGAVIESAEARRPDLRWPLPEGFAERLTGRRVEAVGRRAKYLLADLDGGEVLIVHLGMSGSIRIEGAQVKGRPAGFYHPRGEPGTHDHVVFHLAGGATVTFNDPRRFGAMLLVPYDQLDSHPLLSSLGPEPLGNTFHADYLAQACAGRRTNLKAALLDQKVVAGLGNIYVSEALHRAGLSPRRMASTLASASGAPNVRTERLVTAIRDVLREAIQAGGSSLKDHRQVNGELGYFQHNFKVYDREGEPCPTLRCKGHVQRIVQAGRSTFFCATCQR

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.026 kDa

MPELPEVETVRLGLQPAMEGFRIDRAMANRCDLRFPFQPDFAARLTGQTITGLGRRAKYLLADLSSGDVLLMHLGMSGSFRVVNGAGDATPGEFHHPRSEDRTHDHVVFEMSSGARVIFNDPRRFGFMKIFARAAIDDEPHLKGLGPEPLGNAFDAAMLARACAGKQTSLKAALLDQRVVAGLGNIYVCEALWRAHLSPKRKASTLADRKGAPTDRAVRLVDAIRAVLGDAIKAGGSSLRDHRQTSGELGYFQHSFAVYDREGERCRTPGCNGTVKRLVQNGRSTFWCSGCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.112 kDa

MPELPEVETVRLGLQPAMEGARFDTVALRRADLRFPFQPDFTDRLTGQTVTGLSRRAKYLLADLSSGDALLMHLGMSGSFRVIEPGGEATPGDFHHPRSEDRSHDHVVFSMSSGKTVVFNDPRRFGYMKLFRRAAIEDEPFLKGLGPEPLGNAFDASMLARACAGKKTSLKAALLDQRVVAGLGNIYVCEALFRAHLSPKRLAATLATKAGGPTERAEKLVEAIRTVLHEAIQAGGSSLRDHRQTSGELGYFQHSFAVYDRESEPCRTKGCGGVVKRFVQNGRSTFCCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.722 kDa

MPELPEVETVRRGLEPAMAGARIDGFEARRADLRFALQPDLATRLIGQTVKGLGRRAKYLLAELSSGDVLLMHLGMSGSFRVLQGEASGAPGAFHHPRNDDRAHDHVVFRMSNGAVVVFNDPRRFGYMKILAPGEIADEPFLKGLGPEPLGNSFDAAMLASACAGRKTSLKAALLDQRVVAGLGNIYVCEALFGAHLSPKRLAATLATRTGAPTERAERLVEAIRAVLHAAIKAGGSSLRDHRQTSGELGYFQHSFAVYDREGEPCRSKGCDGVVKRFVQNGRSTFWCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.108 kDa

MPELPEVETVRLGLTPAMEGFRIARAVTNRDDLRFPLQKDFVARLTGQIVTGLGRRAKYLLADLASGDVLLMHLGMSGSFRVVAADGAHTPGEFHHPRSEDRTHDHVVFDMSSGARVIFNDPRRFGFMKIFPRAAIDDEPHLKGLGPEPLGNAFDAVMLARACAGKQTSLKAALLDQRVVAGLGNIYVCEALWRAHLSPKRKAATLANRKNEPTDHALRLTDAIRAVLGDAIKAGGSSLRDHRQTSGELGYFQHSFAAYDREGERCRTDGCGGAVKRFVQNGRSTFWCSGCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.579 kDa

MPELPEVETVRRGLEQKLNNFIIKKVEVCRDSTVAFPNKKEDFIGGLNNSLLYKWNRRGKYLIAELKKLGNENGRFPLEKFSKNNGFLIVHLRMTGYFKFINNSAQPCKHTRIRVFDNKNNELRYIDVRSFGQMWWIKEGLSPNKIIKGLGSLGPEPFSKDFDEIYLKKVISKRTKSIKAILLDQTIVAGIGNIYADESLYSAGISPFREARTIKKNELIKLKESIVTVLKNSIGSGGTTFSDFRDLEGENGNFGLQTNVYRRTGKECRKCGNLIERKKISGRSTHWCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.739 kDa

MPELPEVETVRKGLEQKLKNFIIKRVEICRESTVAYPIDKQDFVKGLQNSLINKWDRRGKYLIAKLKKADRNHTYIENEMSLKNNGSLVVHLRMTGYFTFNKNPTSPCKHTRIRLFDNNNNELRYIDVRSFGQMWWVREGLSPKNIIKGLGALGPEPFSEKFNISYLTKIILNKTRSIKSILLDQTIVAGIGNIYADESLYSAGISPFREARTIEKHELIKLRIAIIEVLKKSIGAGGTTFSDFRDLEGENGNFGLQTNVYRRTGKKCHACKNLIERQKISGRSTHWCRKCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.741 kDa

MPELPEVETVRRGLEQKLNNFIIKKVEVCRNSTVAFPTEKEEFIKGLQNSLLYKWDRRGKYLIAELKKIENENIKFPLKKLRQNNGFLVVHLRMTGYFKFIDNSTQPCKHTRIRVFDKKNNELRYIDVRSFGQMWWIKEGLSPNKIIKGLGSLGPEPFSKNFDEKYLKKVISKRKKSIKAILLDQTIVAGIGNIYADESLYSAGISPFRAAKTIKKNELINLKESIVNVLKKSIGSGGTTFSDFRDLEGENGNFGLQTNVYRRTGKECRKCGNLIEKQKIAGRSTHWCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.195 kDa

MPELPEVETVRRGLIPVLQGAVIESAEARRPDLRWPLPDNFAERLAGRRVEAIGRRAKYLLADLDGGEVMILHLGMSGSIRIEGGAVKGRPGRFHHPRGAGGPHDHVVLHLAGGATVTFNDPRRFGAILIVPYDQIMSHPLLAGLGPEPLGNGFNAEYLARACARRHTSLKAALLDQKLVAGLGNIYVCEALFRAGLSPRRLAHTIATAEGAPTRRAERLVIAIRDVLREAIHAGGSSLRDHRQVNGELGYFQHTFKVYDREGQPCQTLHCKDTIRRIVQNGRSTFYCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.309 kDa

MPELPEVETVRRGLQPVMEGAKIVVAEARRPDLRFPFQPDFVARLQGQVVTGLGRRAKYLMADLASGDVLLMHLGMSGSFRVIKPDNDAAPGEFHYPRGKDTTHDHVLFRMSSGADIVFNDPRRFGYMKVIARNALEDEPLLRGLGPEPLGNEFDAAMLARSCEGKATSLKAALLDQRVVAGLGNIYVCEALHRSHLSPRRIAATLATRKGEPTDHAKRLVGAIHTVLNDAIKAGGSSLRDHRQTTGELGYFQHSFKVYDREGETCKTPACGGTIKRFTQNGRSTFWCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.548 kDa

MPELPEVETVRRGLQPVMEGAKIVAAEARRGDLRFPFQPDFAKRLQGQTVRGLGRRAKYLLADLSSGDVLLMHLGMSGSFRVIKQDDEETPGEFHYPRGKDSVHDHVVFHMSSGADIVFNDPRRFGFMKIIGRGEIEREPHLKDLGPEPLGNEFDAAMLATACAGKKTSLKAALLDQRVVAGLGNIYVCEALFRAHLSPRRLAATLATRKGEPTDHARRLVEAIHAVLNEAIRAGGSSLRDHRQTSGELGYFQHSFQVYDREGEPCRTDGCGGVVKRFVQNGRSTFWCPKCQR

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.669 kDa

MPELPEVETVRRGLQPVMEGAKIVTAEARRGDLRFPFQPDFVKRLQGQTVRGLGRRAKYLLADLGSGDVLLMHLGMSGSFRVIKPEHEETPGEFHYPRGKDSVHDHVVFHMSSGADIVFNDPRRFGFMKIIGRGEIETEPHLKDLGPEPLGNEFDAAMLARACAGKKTSLKAALLDQRVVAGLGNIYVCEALFRAHLSPRRLAATLATRKGEPTDHAKRLVEAIHTVLNEAIRAGGSSLRDHRQTTGELGYFQHSFQVYDREGEPCRTDGCEGVVKRFVQNGRSTFWCPKCQR

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.006 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.006 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.006 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.007 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRKPLKAALLDQRLIAGLGNIYVCEALWRAGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.006 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.006 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.97 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRSDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRAGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.007 kDa

MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRKPLKAALLDQRLIAGLGNIYVCEALWRAGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.124 kDa

MPELPEVEVVRRGLAEHVTGRTVTAVRVHHPRAVRRHEAGPADLTARLLDTTITGTGRRGKYLWLTLGDGADEPLARRESNFALVVHLGMSGQMLLGDVPNANHLRIAALLDDGTTLSFVDQRTFGGWMLADLVTVDGSDVPAPVAHIARDPLDPLFDRDAVVKVLRRKHSEIKRQLLDQTVVSGIGNIYADESLWRAKINGARLASGVSRAKLAELLGAAADVMTDALAQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPRV

mutM

Formamidopyrimidine-DNA glycosylase

293 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.337 kDa

MPELPEVETVRRGLQPAMEGATIVRAETRRKDLRFPFQTDFVARLEGQAVTGLGRRAKYLLADLASGDVLLMHLGMSGSFRVIDAAGVTVPGDFHRPRGEDRVHDHVRFTMSSRAEIVFNDPRRFGYMKIVARSALGDEPLLKGLGPEPLGNEFDAAVLAHGCRNRKTSLKAALLDQRVVAGLGNIYVCEALFRARLSPRRLAATLAMKTGAPSERAERLVGAIRDVLNQAIEAGGSSLRDHRQTTGELGYFQHSFQVYDREGDKCRTPACKGAVKRFTQNGRSTFWCPVCQT

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.193 kDa

MPELPEVEVVRRGLERHIVGASIDSVDILHPRAIRRHLPGAADLAGQLTGERIASADRRGKYLWLVLEPSTVALVVHLGMSGQMLVQPPELPTEKHLRIRARLDSGLDLRFVDQRTFGGWALAPLVDVDGSLVPDSVAHIARDPLDPRFDLAATVKVVRGKHTEVKRALLDQTVVSGIGNIYADEALWRARIHGNRLTDRLSGPKVREVLTAAQEVMREALTQGGTSFDALYVNVNGESGYFDRSLSAYGQEDRPCPRCGTAIRREKFMNRSSFSCPKCQPAPRRSLAKSSV

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.923 kDa

MPELPEVEVTRRGLLPHVVGRRIAAVTVRHRGLRWPVDPQLEMRLAQRVVRRIERRGKYLLLECVSEAAGEPAGWLLVHLGMTGTLRVLPEAPSPGAHDHLDLVLAPGPGAALGTKPGTIVLRFRDPRRFGAILWSTLPEAELPSHPLLRTLGIEPFDPAFDGAWLHRHTRGRSAAIKTVLLAGGIVVGVGNIYASESLFRAGIRPTTPAGRLSRARCDRLAQAVRETLAQAIERGGSTLRDFVGSDGASGYFQLDCLVYDRAGQPCRVCATPVRQIVQGQRSTFYCPNCQH

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.654 kDa

MPELPEVETVRRGLEQKLNNFIIKKVEVCRDSTVAYPSNKEEFIKGLKNSLIYKWDRRGKYLIAQLKEVQNENTEFPLENSQNNGFLVVHLRMTGYFKFIENSTHPCKHTRIRFFDKNNNELRYVDVRSFGQMWWINKDLSINKVIKGLGSLGPEPFSKDFNANYLKEAISKRTKSIKAILLDQTIVAGIGNIYADESLYSAGISPFREARTIKKNELIKLKKSIVIVLKKSIGSGGTTFSDFRDLEGENGNFGLQTNVYRRTGRECRKCGNLIERQKITGRSTHWCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.619 kDa

MPELPEVETVRRGLEQKLKNFIIKRVEICRESTVAYPIDKIDFIEGLQNSLLYKWNRRGKYLIAELKKTVSNNNDANEISFVENGVLVVHLRMTGYFTFNNTLTNPCKHTRIRLFDNNNNELRYIDVRSFGQMWWVRDGLSPNNIIKGLGTLGPEPFSESFNVNYLKKVISNKTRSIKSILLDQTIIAGIGNIYADESLYSAGISPFREARTINKNEIKRLRRAVVDVLKKSIGAGGTTFSDFRDLEGENGNFGLQTNVYRRTGKKCRQCKNLIERQKISGRSTHWCRKCQK

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.695 kDa

MPELPEVETVRRGLEQKLNNFIIKKVEICRYSTVAFPTNKEEFIKGLRNSLIYKWDRRGKYLIAQLKEVQNEHTQLPLENSQNNGFLVVHLRMTGYFKFIENSSNPCKHTRVRFFDKNNNELRYIDVRSFGQMWWINNDLSLNKIIKGLGSLGPEPFSKDFNANYLKKVISKRTKSIKAILLDQTIVAGIGNIYADESLYSAGISPFREARTIKKNELIKLKESIVTVLKKSIGSGGTTFSDFRDLEGENGNFGLQTNVYRRTGKECRKCGNLIERQKITGRSTHWCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.79 kDa

MPELPEVETVRRGLEPVMVGARILSVDQRRPDLRFPFPDRFPERLAGRRILALGRRAKYLLADLDDGDVLIMHLGMSGSFRVEQAGPAKTLSPRGAPPKNAAHDHVVFTLTSGGRIVYNDPRRFGFMQIAARADLAAHPLFRSLGVEPLGNELSGAALARLFAGKTTSLKAALLDQSLVAGLGNIYVCEALHRAGLSPLRQAGSLTKKSGRPTERANRLADTIREVLEEAVAAGGSSLRDHRQTNGALGYFQHNFRVYDRALHPCPTPGCKGEISRITQGGRSSFFCSMCQK

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.017 kDa

MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRGKYLWLTLDAGAPTTGRDDPDTALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFADQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLYVNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR

mutM

Formamidopyrimidine-DNA glycosylase

292 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.001 kDa

MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRGKYLWLTLDAGAPTTGRDDPDAALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFADQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEVKRRLLDQQVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLYVNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.777 kDa

MPELPEVEVTRLGLLPHITGRRIVRAVVRHHGLRWPVDPALPELLAGLTVTRLLRRGKYLLIECVPEVEQSGRAADTVGGWLLIHLGMTGTLRVLETPVPPGLHDHVDIELAGATGVHVTLRYRDPRRFGAVLWHAGDEAGLAEHPLLRNLGIEPFDARFDGDWMFARTRGRRVAIKSALLAGDIVVGVGNIYCSESLFRAGIRPTTAAGRISRPRYAALADAIRATLADAIARGGSTLRDFVGSDGQSGYFQLEAFVYDRAGLPCRACGTPIRQIVQGQRSTFCCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.696 kDa

MPELPEVEVVRRGLERGVVGRTVAEVEVHHLRAVRRHLAGADHFAASLVGQTVATARRRGKYLWLGLTPSEPGGPAVGDALLGHLGMSGQLLVVPADSPDQVHLRVRFRFTDEGRELRFVDQRTFGGLAVVSGGAELPAPIAHIAPDPLSVDFDPERFADALRRRRTGLKRALLDQTLISGVGNIYADEGLWAARLHYARPTETVTRAEALRLLDAVRTVMTAALAAGGTSFDRLYVSTEGVSGLFERSLEVYGRGGQACSRCASTIRRDAFMNRSSFSCPACQPRPRRVR

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.319 kDa

MPELPEVETVRRGLQPAMEGFRIDRAVAHRENLRFPLQKDFVARLTGQTVTGLGRRAKYLLADLSSGDVLLMHLGMSGSFRVVEADGETRPGEFHYPRSEDRTHDHVVFEMASGARVVFNDPRRFGFMKVFPRSEIETEPHLKGLGPEPLGNAFDASLLAKACAGKQTSLKAALLDQRVVAGLGNIYVCEALFRAHLSPKRKASTLANRKDEPTDHAVRLTEAIREVLGEAIKAGGSSLRDHRQTSGELGYFQHAFKVYDREGEPCPTCGGTVQRFVQNGRSTFWCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.191 kDa

MPELPEVETVRRGLQPAMEGFRIDRAVAHRENLRFPLQKDFAARLTGQTVTGLGRRAKYLLADLSSGDVLLMHLGMSGSFRVIGADGETTPGEFHYPRSEDRTHDHVVFEMASGARVVFNDPRRFGFMKVFPRSEIETEPHLKGLGPEPLGNAFDASLLAKACAGKQTSLKAALLDQRVVAGLGNIYVCEALFRAHLSPKRKASTLANRKEEPTDHAVRLTEAIREVLGEAIKAGGSSLRDHRQTSGELGYFQHAFKVYDREGKPCPTCGGTVQRFVQNGRSTFWCPKCQK

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.467 kDa

MPELPEVETVRRGLADRLVDFQIGQVEVCRERAIASPGGSALFIKMLCGMHVGSWLRRGKYLMASLHHEIAQSSADSEPDPDGGWWGVHLRMTGQFQWHEAISSPCPHTRVRIWNKKNEELRFVDTRSFGQMWWVPPGNAPETIITGLQKLGPEPFSSAFNSSYLSKRLKGSKRPIKSALLDQSIVAGAGNIYTDESLFAARIRPHTPSGQLKKVELERLCNCLTEVLRVSIGAGGTTFSDFRDLEGINGNYGGQAWVYRRGGQACRICSTPIRRESLCGRGTHWCPNCQR

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.895 kDa

MPELPEVETVRRGLEPVLMGSRIISVSLGCKNLRFPFPESFSERLTGRIIIKLSRRAKYLLFHLSQNETIVSHLGMSGSWRVEDDLLRKKHSYMGKLVAHDHFIMSFQATNGKIYRLIYNDSRRFGFMLLADTMRLYEHPLLRNLGLEPIDNAVSGAYLQKAFINKKTSLKAALLDQSIVAGLGNIYVCEALWRSYLSPERRALTLASKSAHACELAKCLAQNICDVISEAIFSGGSSLRDYVHIDGSLGYFQHCFSVYGREGKECSRCGMHIVRIVQSGRSSFYCPQCQK

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.87 kDa

MPELPEVETVRRGLEPVITGAKIVSVTLNRRDLRFPFPEAFSERLIGRTIMGLGRRAKYLLFHLSQNETILSHLGMSGSWRIEDDFLRERSSTVSKFVKHDHVVMDIQAKDGKVYHLTYNDVRRFGFMLLVDTRSLYEHPLLKKLGLEPMSNAFSGSYLQEVFVNKKISLKGVLLDQSIVAGLGNIYVCEALWRSRLSPQRGAFTLALKTECARELAASLAQNIRNVITEAISSGGSTLRDYIRTDGSLGYFQHSFSVYGREGKECLHCGIPIVRILQSGRSSFYCSQCQK

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.117 kDa

MPELPEVETVRRGLEPVITGAKIISITLNRRDLRFPFPEAFSERLVGRTIMELGRRGKYLLFHLSQNETILSHLGMSGSWRIEDDLLRKTYSAAGKFVKHDHFLMDIQAKDGKVYHLTYNDVRRFGFMLLLDTNRIYEHPLLKKLGLEPLSNEFSGRYLQEAFVNKKISLKGVLLDQSIIAGLGNIYVCEALWRSRLSPQRGAFTLALKTVCAREFADSLAQNIRNVIAEAISFGGSTLRDYIRTDGSLGYFQHSFSVYGREGKECFQCGIPITRISQSGRSSFYCSQCQK

mutM

Formamidopyrimidine-DNA glycosylase

291 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

33.08 kDa

MPELPEVETVRRGLESVVTDAKIVSVQLNRRDLRFPFPEAFSERLIGRKILELGRRAKYLLFHLSQDETILSHLGMSGSWRIENDLLRTAFSMTSKLVKHDHFIMDIQTRNGDVYHLIYNDVRRFGFMLLVDTDKLYKHPLLNKLGLEPMSHGFSGRYLQKAFVNKKVSLKGVLLDQSIVAGLGNIYVCEALWRSRLSPQRGAFTLASKTVYARELANSLAQNIRNVISEAILSGGSSLRDYMHVDGSLGYFQHAFSVYGREGKECLQCGTPIIRILQSGRSSFYCSQCQK

mutM

Formamidopyrimidine-DNA glycosylase

290 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.814 kDa

MPELPEVETVRRGLEMKIAGRVLVRVAQYRPDLRFPLPERFAARLTGLRVAGLFRRAKYLLIRLEGSAEGPLVWLVHLGMSGTLVVRRGPPGPPGPHDHLVFETDPPPGEAQGWVVTYNDVRRFGFMDLFPEALLDSHPMLACLGPEPLGNGFDAEELSRRLAGKITPIKAALLDQTVVAGLGNIYVCESLFRAGISPRRLAHTVAGRRAGRLVPAIRDVLTEAIAAGGSSLRDYVQSDGELGYFQHSFKVYGREGEPCPGCDCDPVRTGGIARIVQSGRSTFYCPRHQR

mutM

Formamidopyrimidine-DNA glycosylase

290 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.782 kDa

MPELPEVEVTRRGLLPHVVGRRIAAVTVRHRGLRWPVDPGLEACLAHRLVRRIERRGKYLLLECISADAAQPPGWLLVHLGMTGTLRVLPEAPPPGMHDHFDLLLDAGPAPGMLADTIVLRFRDPRRFGAILWTTLPEAELASHPLLSTLGIEPFDPAFDGAWLHRHTRGRSAAIKTVLLSGAIVVGVGNIYASESLFRAGIRPTTAAGRLSRARCDRLAQAVRDTLAQAIERGGSTLRDFVGSDGASGYFQLDCFVYDRAGLPCRVCATPVRQIVQGQRSTFYCPKCQH

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.815 kDa

MPELPEVEVVRRGLQSHAVGAAIEAVEVLHPRAIRRHILGSEDLIGQLTGQTIASAERRGKYLWLVLEPAGVGLVVHLGMSGQMLVQPPTVDWEKHLRIRLALDSGADLRFVDQRTFGGWSISPLVEVDGTMLPESVAHIARDPMDAAFDLESVVKVLRGKHTEIKRAILDQTVVSGIGNIYADESLWRAKIHGNRIAESLTRPKLRELLTAAHSVMGEALDQGGTSFDALYVNVNGESGYFDRSLSAYGQENLPCPRCGAPIKREKFMNRSSFSCPRCQPTPRARRIA

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.848 kDa

MPELPEVEVVRRGLERHIVGASIDSVDILHPRAIRRHLPGAADLAGQLTGERIAGADRRGKYLWLVLEPSTVALVVHLGMSGQMLVQPPELPTEKHLRIRARLDSGLDLRFVDQRTFGGWALAPLVEVDGSLVPDSVAHIARDPLDSRFDLAATVKVVRGKHSEIKRVLLDQTVVSGIGNIYADEALWRAQIHGNRLTDRLTGPRIGAVLTAAQQVMREALSQGGTSFDALYVNVNGESGYFDRSLSAYGQEDRPCPRCGTAIRREKFMNRSSFSCPKCQRAPRRSPAR

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.951 kDa

MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.951 kDa

MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.951 kDa

MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.371 kDa

MPELPEVETIRRTLAPVLIGALVIGALRGEHPEDILLDPWPVFARRVRRHRIVALERRGKYLAARFEDGDRLVIHLGMTGELRLSHPATAPGKHCHLALVLRSLRPLPPSLVDQRQRFLLRYLDIRRFGRIALLDQAGWETFTARLGPEPLDPTLDPRALWSRLRERRTAIKAALLDQALLAGIGNIYADEALFQARLHPARRCQTLSLDEVERLLVALRTVLSAAIENAGTTIRDYRDGQGRAGSFQSRLQVYGKPAGTPCPRCGTGLARIRIAGRSSVFCPRCQPLH

mutM

Formamidopyrimidine-DNA glycosylase

289 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.951 kDa

MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK

mutM

Formamidopyrimidine-DNA glycosylase

288 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.389 kDa

MPELPEVEVTRLGLVPHLTGRRIVRAVVRHHGLRWPVDPALPELLGGRTVARVLRRGKYLLIECVPDIAHGPQAGAGWLLVHLGMTGTLRVLETPAAPGTHDHLDIELADAAGRPITLRYRDPRRFGAVLWHDGDEAALSAHPLLRNLGIEPFDTRFDGDWMYARTRGRSAAIKTVLLAGDIVVGVGNIYCSESLFRAGIRPTTAAGRISRPRYAALAEAIRATLADAIARGGSTLRDFVGSDGQSGYFQLDALVYDRAGLPCRVCGTPIRQIVQGQRSTFYCPACQR

mutM

Formamidopyrimidine-DNA glycosylase

288 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.572 kDa

MPELPEVETVRRGLAPVMVGASFTTVEQRRADLRFPFPDNFAARLEGRRVEALGRRAKYLLADLDDAQVLVMHLGMSGSFRIEKAGDLASPPPGKNAAHDHVVFGLSTGTRIIYNDPRRFGFMHLIARQDLAGHPLFRNVGIEPLGNELEGALLARLFAGKTTPLKTALLDQTLIAGLGNIYVCEALHRAGLSPRRAAGTLAGKKGQPTERAHRLSEIIRAVLEEAIEAGGSSLRDHRQADGALGYFQHRFRVYDREAEPCPREGCGGTIKRIVQAGRSTFFCAKCQR

mutM

Formamidopyrimidine-DNA glycosylase

287 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.559 kDa

MPELPEVETVRQGLAQWVTGRRIAEVEVRHPRAIRRHPAGAAHFADVLVGTTVRDVRRRGKYLWLPLDSGDAVIGHLGMSGQLLLQPGAAPDEAHLRVRFRFADDGPELRFVDQRTFGGLSVSAGGAEMPTEIAHIARDPLDPEFSEAAFVAALRRRRTEVKRALLDQTLLSGVGNIYADEALWRARLHGARPADGLTGPAALRLLGHVRDVLGEAIKEGGTSFDALYVNVNGESGYFDRALNVYGRADQPCRRCGTPVRREAFMNRSSYSCPRCQPRPRRALQASG

mutM

Formamidopyrimidine-DNA glycosylase

287 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.814 kDa

MPELPEVETVRQGLAQWVTDRRIAEVQVLHPRAVRRHAAGAAHFADVLRETTVRDVRRRGKYLWLPLDSGDAVVGHLGMSGQLLLQPAAAPDETHLRVRFRFADDGPELRFVDQRTFGGLSVSAGGAELPTEIAHIARDPLDPEFSDATFVAALRRRRTEIKRALLDQTLLSGVGNIYADEALWRARLHGTRPTDGLTGPAVLRLLGHVRDVLGEAVKEGGTSFDALYVNVNGESGYFDRALNVYGRADQPCRRCGEPVRREAFMNRSSFSCPRCQPRPRRAVPARG

mutM

Formamidopyrimidine-DNA glycosylase

287 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.559 kDa

MPELPEVETVRQGLAQWVTGRRIAEVEVRHPRAIRRHPAGAAHFADVLVGTTVRDVRRRGKYLWLPLDSGDAVIGHLGMSGQLLLQPGAAPDEAHLRVRFRFADDGPELRFVDQRTFGGLSVSAGGAEMPTEIAHIARDPLDPEFSEAAFVAALRRRRTEVKRALLDQTLLSGVGNIYADEALWRARLHGARPADGLTGPAALRLLGHVRDVLGEAIKEGGTSFDALYVNVNGESGYFDRALNVYGRADQPCRRCGTPVRREAFMNRSSYSCPRCQPRPRRALQASG

mutM

Formamidopyrimidine-DNA glycosylase

287 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.814 kDa

MPELPEVETVRQGLAQWVTDRRIAEVQVLHPRAVRRHAAGAAHFADVLRETTVRDVRRRGKYLWLPLDSGDAVVGHLGMSGQLLLQPAAAPDETHLRVRFRFADDGPELRFVDQRTFGGLSVSAGGAELPTEIAHIARDPLDPEFSDATFVAALRRRRTEIKRALLDQTLLSGVGNIYADEALWRARLHGTRPTDGLTGPAVLRLLGHVRDVLGEAVKEGGTSFDALYVNVNGESGYFDRALNVYGRADQPCRRCGEPVRREAFMNRSSFSCPRCQPRPRRAVPARG

mutM

Formamidopyrimidine-DNA glycosylase

287 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.062 kDa

MPELPEVETVCRGLNRLTLEQTIGGGEVLLDRSLAYPVSVEDFQKQITGCRLVGWQRRGKYLLGELRSNQAPGPAGWLGCHLRMTGQLLWTERDQQRPRHTRVVLHFEGGWELRFVDTRTFGKVWLLPGDRPWAEVMTGLGQLGPEPFGADFTAEYLYEKLKSSRRPLKNALLDQRLVAGLGNIYADEVLFFCGFHPTMASNQVSLQDCELIHQQIQATLTAAIEAGGTSFSDYRQVTGINGNYGGMAQVYGREGEPCRHCGTVIAKIKLGGRSAHFCPQCQPKLER

mutM

Formamidopyrimidine-DNA glycosylase

286 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.343 kDa

MPELPEVETVMRGMRLHLDGKTIARVAVRRADLRFPFPADLVARLEGATITGFARRAKYILIRLDTGDTLLLHLGMSGRVLLSLPGDAPVPDRHEHFFFETTDGTRCGLIDPRRFGAVDLMPTAEERAHRLLARLGPEPLGNQFSQHWLQEVLARRRTSIKAALLDQTVVAGLGNIYVSEALFRAGIHPARLACTLDAAEDARLVQAIRAVLREAIAAGGSSLRDYVQPDGELGYFQHAWRVYGRAGQGCPDCPGPPACHGVERLEQAGRSSFFCPLCQPPPGKVS

mutM

Formamidopyrimidine-DNA glycosylase

286 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.48 kDa

MPELPEVETVRKGLEKRLKNFYIDNVEVLSERSIASNGGSNVFIFNLKDLVFGRWSRRGKYLIASLCKESDLIEEIPSGTLVVHLRMTGYFEWHQNTKAPCTHTRVRFWNKKGSEIRFIDIRNFGQMWWIPPNKLPSEVINGLKNLGPEPFSKDFNPEYLKYCLKGRKRSIKSSLLDQSILAGVGNIYADESLFEAGITPIKASGDLNGCELKKLCKSLTRILKASIGKGGTTFSDFRDLEGLNGTYGGYAWVYRRNQKPCRKCGTLIEKTKVAGRSTHWCPNCQN

mutM

Formamidopyrimidine-DNA glycosylase

286 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.35 kDa

MPELPEVEVVRRGLHHHLVGKTIASTLVYHERAVRRQSGGAVELAGLLAGQQISGTGRRGKYLWLTLEGSSGAQALVVHLGMSGQMLIGPISRPQHLRIAATLDDGSVLSFVDQRTFGGWMVTDLVTVDGSELPEPVAHIARDPLDELFEIGAVVTRLRGKHTEIKRALLDQTVVSGVGNIYADEALWQARVHGRRLTDGMSRAKLTEVLDSAAAVMRLALAQGGTSFDDLYVNVNGESGYFDRSLEAYGREGEPCRRCGRAMRREAFMNRSSYFCPSCQRLVEPR

mutM

Formamidopyrimidine-DNA glycosylase

286 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.331 kDa

MPELPEVEVVRRGLERWVAHRTVADVEVLHPRAVRRHTAGGEDFAHRLKGRRVGVPSRRGKYLWLPLETTDTAVLAHLGMSGQLLVQPHDCADERHLRIRVRFADALGTELRFVDQRTFGGLSLHDTTPDGLPDVIAHIARDPLDPLFDDAAFHEALRRKRTTVKRALLDQSLISGVGNIYADEALWRARIHYERPTAGFTRPRTAELLGHVRDVMNAALAVGGTSFDSLYVNVNGESGYFDRSLDAYGREGLPCRRCATPMRRRPWMNRSSYFCPKCQRAPRVTV

mutM

Formamidopyrimidine-DNA glycosylase

286 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.511 kDa

MPELPEVEVVRRGLERWAAHRTVADVEVLHPRAVRRHVAGPDDFAHRLKDHRIGTPSRRGKYLWLPLEDTDQAVLAHLGMSGQLLVQPHETPAEKHLRIRVRFADALGTELRFVDQRTFGGLSLHDTSADGLPDVIAHIARDPLDPLFDDEAFHHALRRKRTTIKRALLDQSLISGVGNIYADEALWRARLHYERPTATLTRPRTTELLGHVRDVMNAALAVGGTSFDSLYVNVNGESGYFDRSLDAYGREGMPCRRCATPMRRRPWMNRSSYFCPKCQRPPRVTP

mutM

Formamidopyrimidine-DNA glycosylase

286 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.938 kDa

MPELPEVEVVRRGLERWVSGRTVSEVEVLHPRAVRRHLAGGVDFAARLAGARFGAAMRRGKYLWVPIDEASASLLGHLGMSGQLLVRPADAPDEKHLRIRMRFDDALGTELRFVDQRTFGGLSLHANTPDGLPETIAHIARDPLDPLFDDAAFHTALRLRRTTVKRALLDQSLISGVGNIYADEALWRARLHYDRPTATLTRPRSAELLGHARDVMNAALAQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCHRCGTPMRRRAWMNRSSYYCPRCQRPPRASS

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.098 kDa

MPELPEVETVRLGLEKVTVGMQIMGGEVLYPRTIAHPQSPQVFIQGLQDATFLSWMRRGKYLLSQLSFSTQQPSGWLGVHLRMTGQLLWVAQDEPVQKHTRVRLFFVNNRELRFVDQRTFGQMWWVAPTEDPKQVISGLQKLGPEPFSEEFSVDYFWESLQGRKRSIKSALLDQALVAGVGNIYADEALFMSEIRPTTACHQLQTEQVQRLRTAIIEVLSTSIGAGGTTFSDFRDLKGVNGNYGGMAWVYGRQGQPCRTCGQTIERIKLVGRSTHFCPQCQPES

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.544 kDa

MPELPEVETIRRGLARHLVGRRIGYAEVFHPRAVRRHSGGAADFTGRLIGRRIQAVLRRGKYLWFALDSDLALLAHLGMSGQFLLADAASPSPKHLRARFAFTDGDPELRFVDQRTFGGLTLAPLIADVPASISHIAPDILDVAFDEAEFHRRFTQRRTGVKRALLDQTLISGVGNIYADEALWRARLHYATPTVDISAATCRRLLAALRAVFRAALRAGGTSFDALYVNVNGQSGFFDRSLAVYGRAGQPCRRCGTAIVREPFMNRSSFRCPACQPVPRRPHW

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.344 kDa

MPELPEVETLRRDLLIHLPGERVVGVEVLRSDSVGYPADPAIFIEQMQGQIFSDRMLRRGKYLLLYFARGAALGVHLRMSGRLLWRCGEAPLEPHTRVRIPMASGHELRFEDMRVFGRLWLIPVGVPPERVMGGLTRLGPEPFAEMFDGPYLAGRFAGRNQPVKSALLDQQLVAGVGNIYADEALFSSGIHPALPVGGLDAAALERLHRAVVKVLEAGIAQRGATLRNYTDAQGINGNYAGTAWVYGRKGQPCRVCNTPIERIRLAGRSTHFCPTCQRAQQSVQ

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.376 kDa

MPELPEVEVTRRGLLPHVVGRRIADVTVRHRGLRWPVEDDLEARLAGRLVRRIERRGKYLLLECVDEATDDAGWLLVHLGMTGTLRVLPDAPPAGAHDHLDLVLDDAGGSRIVLRFRDPRRFGAVLWSPLSEAMLPGHPLLRGLGIEPFDSHFDGSWLHRHTRGRSAAIKTVLLAGNIVVGVGNIYASESLFRAGIRPTTPAGRLSLARCERLAQSVRETLAQAIERGGSTLRDFVGSDGASGYFQLECFVYDRAGEPCKVCGTPVRQIVQGQRSTFYCTHCQH

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.563 kDa

MPELPEVETVRRGLEPVMTGQRIIEADIRRPDLRWPLPANMQTRLEGKRILRLARRSKYILAELDSGETLIIHLGMSGRILIHGGQAPGAFHHALPSLEKHDHVVLDFDTGARVVFNDARRFGAMDLCETTEIDQHPMLATLGPEPLGNAFHEAYLTTRLKGRMTPIKSALLDQKVVAGLGNIYVCEALFQAGISPLRKAGRVSETRIASLVPIIRTVLGDAIEAGGSSLRDYRQTDGDLGYFQHRFRVYDRENAPCVTAGCPDVVRRVVQSGRSSFYCPSCQR

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.749 kDa

MPELPEVTTVINELKETVLNKPLDQVQVNLRKVLKNIDPQLLNKQLKNQFFTDIKRKGKYIIFLLSNGLYLVSHLRMEGKYFFEERGSKFNQKHVLVEFHFDDGSQLNYHDTRQFGTFHLYEKLEQAAQLNKLAFDPLEAGFDYRKIFQKAQNSKRKVKTFILDQTVISGIGNIYADEILFASKINPETMVDQLTIKEIEILCKNATKILAKAIVMKGTTISSFSFKKDHTGGYQNFLKVHTKKDQPCSVCNQLIVKKKINGRGSYFCLNCQKITTKVSTKLNP

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.716 kDa

MPELPEVETVRRGLELVTLKQPIVDVEVLLARSIALPKEPQAFIEHLRDRRIEQWQRRGKYLLATLDDGSRLVIHLRMSGQLLWLTTPQPPCPHTRVRWFFPTRAELRFVDQRTFGRCWWLPPDCRVAEAIPALATLAPEPLSEAFTVAFLAARLAHCRRSIKTALLDQSIVAGMGNIYADESLFLSGLHPTQSAHTLTPEQVQRLHGVICQVLREGIAAGGTTIRTFMSPAGVNGHYGGQAWVYGRKGEACRVCGTTIERLRLAGRSSHYCPQCQPLSSAIGK

mutM

Formamidopyrimidine-DNA glycosylase

284 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.631 kDa

MPELPEVETVRRGLELVTLKQPIVDVEVLLARSIALPKEPQAFIEHLRDRAIEQWQRRGKYLLATLDDGSRLVIHLRMSGQLLWLTTPQPPCPHTRVRWFFPTRAELRFVDQRTFGRCWWLPPDCRVAEAIPALATLAPEPLSEAFTVAFLAARLAHCRRSIKTALLDQSIVAGMGNIYADESLFLSGLHPTQSAHTLTPEQVQRLHGVICQVLREGIAAGGTTIRTFMSPAGVNGHYGGQAWVYGRKGEACRVCGTTIERLRLAGRSSHYCPQCQPLSSAIGK

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.764 kDa

MPELPEVETVRRGLEPAMAGRLIAEARVNRADLRWPFPPRMAERLTGQRVLRLRRRSKYILADLSGGQSLLIHLGMSGRMLVSGAQLGEFFHGHPAPSRHDHVVLEMEGGARITFNDARRFGAMDLVATEAAEAHPLLAVLGPEPLGNAFDGAYLAARLEGRRTPIKAALLDQRIVAGLGNIYVCEVLFRAGLAPGRLAGSLSRAEAEGLVPLIREVLLEAIEAGGSSLRDYRQADGELGYFQHTFRVYGREGLPCVTPGCSGTVGRIVQSGRSSFHCPLCQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.823 kDa

MPELPEVETVRRGLEPAMAGRLIAEARVNRADLRWPFPPRMAERLTGQRVLRLRRRSKYILADLSGGQSLLIHLGMSGRMLVSGAQLGEFFHDHPAPSRHDHVVLEMEGGARITFNDARRFGAMDLVATEAAEAHPLLAVLGPEPLGNAFDGAYLAARLEGRRTPIKAALLDQRIVAGLGNIYVCEVLFRAGLAPGRLAGSLSRAEAEGLVPLIREVLLEAIEAGGSSLRDYRQADGELGYFQHTFRVYGREGLPCVTPGCSGTVGRIVQSGRSSFHCPLCQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.092 kDa

MPELPEVETVCRGLNQLTFGQTIRGGKVLLPRTLAYPVSIEEFLEQINNATFGQWQRRGKYLLVPLEEKKGWLGVHLRMTGQLLWVKQNEPLSRHTRLRLFCDRSKELRFVDIRTFGKVWWVPPNQPPETIITGLQKLGLEPFSNAFSLDYFIDKLKGRQRNIKTILLDQSVVAGIGNIYADEALFKSGIRPTTLGKELSQPQVKRLREAMIEVLKTAIEEGGTTFSDFRGVTGINGNYSGVAWVYGRHNQPCRVCGTPIERIKLGGRSSHFCPQCQPLGNKK

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.298 kDa

MPELPEVETVKRGLKNRLKDFYIHDVEVITPRSISSEGGSKAFVKNIIGLKSGEWTRRGKYLICSLHSSDREEIAGWWVVHLRMTGQFQWFQKKTKSCKHTRVRIWNKDGAEIRFVDTRNFGQMWWISPTFLPTEKITGLKKLGPEPFSKEFNPFYLQESLKKRKRSIKSSLLDQSIVAGAGNIYADESLFQAGILPTKESKKLNKTEIKKICTSLTHILKISIGEGGTSFKDFRDLEGVNGKYGGQAWVYGRENKPCRKCGVKILKAKVAGRGTHWCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.151 kDa

MPELPEVETVRRGLAPVLEGARIAQAAVNRPDLRWPFPDNMAQRLTGATVTALRRRSKYILADLDTGETLLIHLGMSGRMQISGDVIGSFHHTHPAAAKHDHVVLDTDAGARITFNDARRFGAMDLMDTATQDQHWLLRDLGPEPLGNAFNEAHLVAAFKGKRSPVKTALLDQRIVSGLGNIYVCEALWRAGISPLRQAGKIAAVRVATLVPIIRDVLTEAIEAGGSSLRDHRQATGELGYFQHTFRVYGREGQRCQTPDCAEKILRKVQSGRSSFYCPACQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.795 kDa

MPELPEVETVRRGLEPAMAGRLISEARVNRPDLRWPLPPRMAERLTGQRVLRLRRRSKYILADLSGGESLLIHLGMSGRMLVSGARVGDFVHDHPAPARHDHVVLEMEGGARVTFNDARRFGAMDLVPTEAAETHPLLASLGPEPLGNAFDGAYLAARLTGRRTPVKAALLDQRIVAGLGNIYVCEVLFRAGLAPVRLAGSLGEARAAGLVPIIREVLSEAIEAGGSSLRDYRQADGELGYFQHTFRVYGREGQPCVTPGCRGLVGRIVQSGRSSFHCPECQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.839 kDa

MPELPEVETVRRGLEPAMAGRLIAEARVNRADLRWPFPPRMAERLTGQRVLRLRRRSKYILADLSGGQSLLIHLGMSGRMLVSGAQLGEFFHDHPAPSRHDHVVLEMEGGARITFNDARRFGAMDLVATEAAEAHPLLAVLGPEPLGNAFDGAYLAARLEGRRTPIKAALLDQRIVAGLGNIYVCEVLFRAGLAPGRLAGSLSRAESEGLVPLIREVLLEAIEAGGSSLRDYRQADGELGYFQHTFRVYGREGLPCVTPGCSGTVGRIVQSGRSSFHCPLCQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.339 kDa

MPELPEVQHTADSLGIQIAGARIARVERLDWTRMVETPSPDEFIRLLTGRQVRGWDRRAKWILLFLDDGWTLALHLRMSGSLTVHPAEAQPDKHTHLALRLEDGRQIFFLDPRKFGRARLLDSAGLAALDAAHGDEPLSDAFTVERLASLLRNRKRAIKPLLLDQSVIAGIGNIYADEALWRARIHPLRPAADLSAAEVAALHDGIRAALRQALANGGSTLRDYRNSYGAGGTNQEHFNAYDREGRPCPRCGATIIKTVVAQRGTHYCPACQAIPSATTNRRE

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.35 kDa

MPELPEVETVRRGLTPAMEGVVIARADVNRPDLRWPFPADMAARLTGKRVERLRRRSKYILMDLDSGETLLVHLGMSGRMLVSGDPLGQFVHSHPAPEKHDHVVFHMANNARITFNDPRRFGAMDLMETASADTHKLLSVLGPEPLGNDFHESHLIEAFKNRNSPVKSVLLDQRIVSGLGNIYVCEALFRAKIHPIRKAGKISGARVATLVPIIREVLAEAIEAGGSSLRDFKQADGELGYFQHSFDVYGREGAPCKGEGCTGQIKRIVQSGRSSFYCAQCQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.12 kDa

MPELPEVETVRRGLAPAMEGAVIARAEVNRPDLRWPFPDRMAERLTGQRVERLRRRSKYILADLSGGETLLIHLGMSGRMTVSGDPLGQFVHDHPAAQKHDHVVFHMDNGARITFNDPRRFGAMDLMATATADEHKLLMVLGPEPLGNDFHEDYLVAALKGRNTPVKSALLDQGIVAGLGNIYVCEALFRAGVSPRRKAGQIAAARVSALVPIIRQVLSEAIEAGGSSLKDFRQADGELGYFQHSFDVYGREGEPCRRAGCDGTVQRITQSGRSSFYCAQCQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.312 kDa

MPELPEVETVMRGLQPSMEGVVIARADVNRPDLRWPFPDRMTERLSGRRVLSMRRRSKYILADLDSGETLLVHLGMSGRMTVSGDPLGQFVHSHPQLEKHDHVVFHMDNGARVTFNDPRRFGAMDLLETAKADSHKLLAVLGPEPLGNDFHESHLVSAFKGRRTPVKSALLDQGIIAGLGNIYVCEALFRAGISPRREAGKISTSRVTSLVPIIRQVLQDAIAAGGSSLKDFRQANGELGYFQHTFDVYGREGEPCRRAGCTGTVTRITQSGRSSFYCGKCQR

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.275 kDa

MPELPEVEVVRRGLHSHVVGKTIGAVRVHHPRAVRRHEAGPADLTARLLGARITGTDRRGKYLWLLLDGRDTALVVHLGMSGQMLLGAVPRAEHVRISALLDDGTVLSFADQRTFGGWMLADLLEVDGSVVPEPVAHLARDPLDPRFDADAVVKVLRRKHSEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARIADALTRKQLTAVLDAAADVMRDALAKGGTSFDSLYVNVNGESGYFDRSLDAYGREGESCRRCGAVMRREKFMNRSSFYCPKCQPRPRL

mutM

Formamidopyrimidine-DNA glycosylase

283 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.164 kDa

MPELPEVEVVRRGLHAHVVGKTIGAVRVHHPRAVRRHEAGPADLTARLLGARITGTDRRGKYLWLLLDGCDTALVVHLGMSGQMLLGAVPRAEHVRISALLDDGTVLSFADQRTFGGWMLADLLEVDGSILPRPVAHLARDPLDPRFDAAAVVKVLRRKHSEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARIAATMTGRQLTAVLDAAAEVMRDALAQGGTSFDSLYVNVNGESGYFDRSLDAYGREGESCRRCGAVMRREKFMNRSSFYCPKCQPRPRL

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.224 kDa

MPELPEVETVCRGLNELTSGKVIKDAEVLLPRSLASPSSVDEFLSNIRGVIFGEWQRRGKYLLGTLVKESGEAAGWLGVHLRMTGQLLWVNQSEPLQIHTRLRLFCGENKELRFVDIRTFGKVWCVPPKTTPETIITGLKKLGVEPFSDDFSDDYFTTKLNGRQRNIKTLLLDQEIVAGLGNIYADEALFKSGVHPTTLGKNLKPQQIEQLRIAIIEVLETAIEKGGTTFSDFKGVTGINGNYGGTAWVYGRTGEPCRVCGTSIERLKLGGRSAHFCPRCQA

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.248 kDa

MPELPEVETVRKGLEKLLNDFYIERIEVLKERSIASNGGSKSFIDNVKNSYLGNWERRGKYLIGSLLTKEKFSKGFLVVHLRMTGQFKLLEKEVLACKHTRVRFFEERGRELRFIDIRNFGQMWHVPSSRSVPEIVSGIKRLGPEPFSDDFNSHYLEEYLKKKTRSIKSALLDQRTVAGVGNIYADETLFDAGINPKTESRNLKSNELKRLCNSLIKILNISIGEGGTTFSDFRDLEGGNGNYGGQALVYRRSGKNCKKCGEKILREKICGRSTHWCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

32.28 kDa

MPELPEVETVRKGLEKLLNDFYIERIEVLKERSIASNGGSKSFIVSVKNSYLGSWERRGKYLIGSLLTKEKFSKGFLVVHLRMTGQFKLLEKEVLACKHTRVRFFDERGRELRFIDIRNFGQMWHVPSSRSIPEIVSGIKRLGPEPFSDDFNSHYLEEYLKKKTRSIKSALLDQETVAGVGNIYADETLFDAGINPKKESRNLKSTELKRLCNSLVKILNISIGEGGTTFSDFRDLEGINGNYGGQAWVYRRSGKNCKKCGEKILREKICGRSTHWCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.835 kDa

MPELPEVEVVRRGLAAHVTGRTISAVRVHHPRAVRRHEAGPADLTARLLDSVITGTGRRGKYLWLTLGDGSAVVVHLGMSGQMLLGPVRNENHLRIAVLLDDGTALSFVDQRTFGGWMLADLVTVDGSDVPAPVAHIARDPLDPLFDRAAVVNVLRRKHSEIKRQLLDQTVVSGIGNIYADESLWRAKINGARLASGVSKAKLAELLDAATDVMTDALAQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPRV

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.515 kDa

MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLGTRINGIDRRGKYLWFLLDTDIALVVHLGMSGQMLLGTVPRVDHVRISALFDDGTVLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEAVVKVLRCKHSELKRQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTRRQLAAVLDAAADVMRDSLAKGGTSFDSLYVNVNGESGYFDRSLDAYGREGEGCRRCGAVMHREKFMNRSSFYCPRCQPRPRR

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.515 kDa

MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLGTRINGIDRRGKYLWFLLDTDIALVVHLGMSGQMLLGTVPRVDHVRISALFDDGTVLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEAVVKVLRCKHSELKRQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTRRQLAAVLDAAADVMRDSLAKGGTSFDSLYVNVNGESGYFDRSLDAYGREGEGCRRCGAVMHREKFMNRSSFYCPRCQPRPRR

mutM

Formamidopyrimidine-DNA glycosylase

282 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.794 kDa

MPELPEVETVRRGLTQQTLQRVCTGGEVLLSRTIATPTPELFLVALQQTQIQEWRRRGKYLLADLSREGEPAGTWGVHLRMTGQFFWTEPATPLTKHTRVRLRFEGDRELRFIDIRSFGQMWWVPPDRPVESVITGLSKLGPEPFAPEFTARYLRDRLRRSQRPIKTALLDQSLVAGIGNIYADESLFRTGIHPTTPSDRLTKIQAEKLREAIVEVLTASIGAGGTTFSDFRDLTGVNGNYGGQAWVYGRKDQPCRTCGTPIQKLKLAGRSSHFCPRCQPCS

mutM

Formamidopyrimidine-DNA glycosylase

281 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.195 kDa

MPELPEVETVRLGLTPALVGERLSRVAARRPALRLPIPVDLVQRLTGKVVGSLDRRAKYLLLRMIDGPVALIHLGMSGSMTVGPLAGHAEPGPHDHILFETEAGLRVTFRDPRRFGLITLAEPETLDDHPLLAKLGPEPLSEAFDAEVLVRRLNGRQAPIKAALLDQGVVAGLGNIYVSEALFRAGISPLRPAASVTGAWAEALVAAIRAVLGEAIAAGGSSLRDHRQTDGALGYFQHRFAVYDRVGQPCPGCDCDVARTGGIERMVQSGRSTFFCGRRQR

mutM

Formamidopyrimidine-DNA glycosylase

280 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.41 kDa

MPELPEVETVRKGLEKLVVGKTIQEVIVFWPRIIESPEVDVFQGQLAGQTIEGIERRGKFLIFKLSDNDMISHLRMEGKYEFHQADDEIAKHTHVMFTFTDGTQLRYLDVRKFGRMTLVPKNQGHQYKGILALGPEPTPDVFQLATFQQGLKKHHKAIKPLLLDQKLVTGLGNIYVDEALWQAQIHPEQPADSLKPAEVATLYQAIIDVLARAVEAGGTTIRTYLNALGEAGTFQVALNVYGQTGLPCNRCGTPIVKTKVAQRGTHYCPQCQQLKGRRLK

mutM

Formamidopyrimidine-DNA glycosylase

280 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

30.819 kDa

MPELPEVETTRRKIEPLLRGKTIERIVHDAPHRYRNTERAHGRQVRGLTRRGKYLLLHLAAADAAEDEPHDLELIVHLGMTGGFRLEEGPHTRVTFELGSGEKLYFNDPRRFGKVVAVAPGDYASMPTLAAMGPEPLSDDFTEAEFVALAARCGPVKPWLLSQKPVSGVGNIYADESLWHARLHPAQTRLNADEAGRLYRAIREVMAAAVDKGGSSLGNGVGNYRQHDGEGGGFQHSHHVYGRAGQPCDRCGTPIEKIVLGQRGTHFCPVCQPLRTDRSA

mutM

Formamidopyrimidine-DNA glycosylase

280 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.443 kDa

MPELPEVETTRKGIQPKVEGQAIQKIIIRNGKLRWPVDPSLVEKLPGLVVLSIKRRAKYLLLETDQGHLIIHLGMSGNLRVLPQHEPAVKHDHIDLLLENGFLLRYHDPRRFGSWLWTEAPIQEHSLLKSLGPEPLTDAFNAEYLFQKLQGRKTAIKTFIMNNQIVVGVGNIYANESLFLSGIHPTRPAQSLTLTEATKLTAHIKTVLSAAIEQGGTTLKDFLTPDGKPGYFEQKLNVYGRENLPCPQCDSAIEKVVLNQRAAYFCSNCQKQLDSTVKIK

mutM

Formamidopyrimidine-DNA glycosylase

279 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.928 kDa

MPELPEVETLKNSLKDKLIGLIVENVELKRDNLRYKLSPLLATEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEQEFFNDLGIEPFSDLLTLEYLKDKLQTRKRPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGSDLRDDEIENLIKSIRDVLTKAITAGGTTLKDFVNGDNKPGYFTQQLTVYGKEGQSCLSCSSTIIKTKHSGRSTFYCKTCQYRLASFTI

mutM

Formamidopyrimidine-DNA glycosylase

279 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.168 kDa

MPELPEVEVTRRGLEPLIGATVTQAVIRQPAMRWPIPSHLPQVLHGARLLELRRRGKYIIARFESGCLILHLGMSGRLCLLESDTFPEKHDHFDLHFADGRVMRMRDPRRFGAVLWAGDQPDEHSLLKVLGQEPLDEAFNGEFLQQAIRTRSSPIKTVIMDSHLVVGVGNIYASESLFRAGIHPETPARALTLAQCRRLVEEVKLTLQDALQAGGSSLRDFFGADGNPGYFQQTYFVYGRTGQPCRVCQTPIAVLRLGQRSTFYCPACQQGQPPSNAMP

mutM

Formamidopyrimidine-DNA glycosylase

278 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.252 kDa

MPELPEVENVRRGLETLAVGKTVSAIDIRWSKIIVNPDEVFTAGLVGQQITAVDRRGKYLLIRFGEQLTVVSHLRMEGKYEVVAKEAPISKHTHVIFEFTDGQQMRYLDTRKFGRMQLIETGQENTVAGLKDLGPEPTPTTFLKADFYQRLQKHHKAIKPLLLDQKVVTGLGNIYVDETLWLSHIHPETPANDLTRAETDRLHDEIIAELELAINHGGTTVNTFLNATGHAGAFQEMLHVYGKKGVPCERCGTPIEKIKVAQRGTHFCPKCQIKRNAK

mutM

Formamidopyrimidine-DNA glycosylase

278 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.252 kDa

MPELPEVENVRRGLETLAVGKTVSAIDIRWSKIIVNPDEVFTAGLVGQQITAVDRRGKYLLIRFGEQLTVVSHLRMEGKYEVVAKEAPISKHTHVIFEFTDGQQMRYLDTRKFGRMQLIETGQENTVAGLKDLGPEPTPTTFLKADFYQRLQKHHKAIKPLLLDQKVVTGLGNIYVDETLWLSHIHPETPANDLTRAETDRLHDEIIAELELAINHGGTTVNTFLNATGHAGAFQEMLHVYGKKGVPCERCGTPIEKIKVAQRGTHFCPKCQIKRNAK

mutM

Formamidopyrimidine-DNA glycosylase

278 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.659 kDa

MPELPEVEVTRLGIAPHLEGRKVSAVKIIDGRLRWPVPANLTKTLPGQTVNGIERRGKYLLLEMDTGYLLIHLGMTGTLRVLPSSDPLKTHDRVTLEFGKLSLRLHDPRKFGAVLWHPKSKGPIKKFILLQKLGVEPFSSEFSGELGAEILYQTSRKRSVAVKQFLLAGQAVVGVGNIYCSESLFEAGIHPAKAAGKLTRPQCSRLAKAVRSILKKAIEAGGSSLKDFVNSDGDPGHFMVQTKVYDRKGLPCKVCKTPISQMVQGQRTTYFCSQCQKR

mutM

Formamidopyrimidine-DNA glycosylase

278 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.314 kDa

MPELPEVETSRRGIEPYLVGQTILYAVVRNARLRWPVSDEILTLSDQPVLSVQRRAKYLLLELPKGWIIIHLGMSGSLRVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWAKDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLFAAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVYGRAGEPCRQCGHPIEIAKHGQRSTFFCRHCQFRPIWPIMLW

mutM

Formamidopyrimidine-DNA glycosylase

278 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.657 kDa

MPELPEVETVRRGLADRLSLFEIERVEVCRSRAIASSGGVAAFLVGLTGARVGTWSRRGKYLMAALEPNRGIWGVHLRMTGQFQWIEEPSTPCTHTRVRFWNANGHELRFVDVRSFGEMWWVPPDVELTVGIPGLARLGPEPFSEAFSAPYLKRQLKNSSRPIKTALLDQALVAGVGNIYADESLFSAGIPPLTPAGRLTLAQLERLRSSLVEVLTTSIGAGGTTFSDFRDLEGVNGNYGGQAWVYRRGGEPCRRCGTIIRRDKLSGRSTHWCPTCQG

mutM

Formamidopyrimidine-DNA glycosylase

278 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

32.21 kDa

MPELPEVRVVCKSLNEKVQNLVFKKVEIFNPKLFKEYDPSYFQEFLIGEKILKISNLGKNIIYFLTNNKIMLSHLRMEGKYSFYEQKPKETLKHIQAIFYFENGSELHYRESRPFGTFHIRYLNNYLKIDPLAKVAQSPGEIDFETFYNRLSKKALAIKPTLLDQSIVSGIGNIYADEILFASKIHPATPSNLLSKDKVKEILKNAIEILDKSTELGGSSINSYESLNKKEGQYQNFLKVHTKKGEFCIKCSSKIEKIKFKGRGTYFCPTCQKQKDFI

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.392 kDa

MPELPEVETTRRGLAPLLEGRRVTGMTVRQARLRWPVPAGLPDAITGQTIRAVDRRAKYLLFRTPAGTLILHLGMSGSLRVIPGQQAGACAVPPGRHDHVDLRLADGSCLRYTDPRRFGSLHWCTGEPEAHWLLHRLGPEPFDTAFDGDRLHRLSRGRRTSVKAFIMDSGIVVGVGNIYASESLFRAGIHPGRPAGRVGLARYRRLAGAVREVLAEAIAAGGTTLRDFTASDGRPGYFAQTLNVYGRAGAPCPRCGRSIRQRRIAQRSTWYCPGCQR

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.933 kDa

MPELPEVETVRRGLNQLTLNRKITGGDVLLHRTIAHPFSVGDFLNGITGDSISAWHRRGKYLLASTTSAAWLGVHLRMTGQLLWLNQDEPLHKHTRVRIFFEDQQELRFVDQRTFGQMWWVSSGMAVESVITGLAKLAVDPFSPEFTVEYLANKLHNRRRPIKTALLDQSVVAGLGNIYADEALFKSGVLPETLCTEVQLKQIELLRTAIIQVLETSIEAGGTTFSNFLNVKGVNGNYGGVAWVYNRAGEPCKVCGDVIQRIKLGGRSSHFCRQCQV

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.475 kDa

MPELPEVETVMRGFRDAFEGHRISHVTVNRPDLRWPFPADLREKLEGHHVLSFRRRAKYILVRLEGGWSMLLHLGMSGRLTIGRAGTNATPPAHEHLVLETDSGARAGLVDPRRFGMVDLVRTSEEDSHRLLAHLGMEPLSDAMTGPALAELFRGRRSPIKSALLDQKLIAGLGNIYVCEALFRCGIHPERQACTLTGEETAALAEAIPQILEQAIASGGSSLRDYVQADGTKGAFQDLHLVYGREGVPCPNCGAEHPIQRITQAGRSTFFCPTCQK

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.332 kDa

MPELPEVEVCRRGLEPELAGQVIQGVVIRAPKLRHEIPPALATLLPGCRVVAVRRRGKYLLLDCERRGVQGTLIIHLGMSGNLRFVPFDLPPAKHDHFELVLAGQILRFADPRRFGVVLWQPGPPASAECHPLLATQGIEPLSEMFTAEWLYEAIARRSGPIKPTLMDSHLVVGIGNIYASESLFRAGISPLRAANRVSRARYEILVPAIRETLSDAIAAGGSSIRDYVHSDGGAGCFQIQAGVYDRANQPCLRCGGVVRQIRQAGRSTYYCTGCQH

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.891 kDa

MPELPEVEIILRGISPLICGRTIVAVGGSGKQLRLPLPLPELNRDASGKEITRLERRGKYISIFLNDGGILVLHLGMTGQLGVFPKEQARAKHDHFWCRLDNNQEFRYNDTRRFGSIRFLPAGKSRMLQESLYQKLGPEPLGETFTADYLRRAAEGKSLAIKNFIMDSHIVVGIGNIYANESLFKAAIHPARSVQSIEQEEWEKLARCIQQILLHAIDCGGSTISDFVNAKGGQGYFQMNFKVYGKKSLPCPHCQGPISSEKIGGRASFFCPSCQRL

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.598 kDa

MPELPEVETIVRSLEKHLSGLVITSVDLFKPEVIRTPRVDIFTDQIVGRQFQKKLGRRGKYLLLHMSDGLTLVIHLRMTGRLIYCDADLPLEKHTHVIFHLDNGKQLRFADVRRFGRMSLVPTREVPHLPGIKEMGPEPLDTAFSREYLKKELRRRRTRIKSLLLDQCFVAGLGNIYADEALHEAKIHPERLAPDLTSREASGLHKAIIEVISSGIKHRGTTFRDYVDGEGRSGSYQHQLKVYNREGLPCPHCGKPIQRIKVAGRSSYYCSSCQKAK

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.478 kDa

MPELPEVETVRRSLAGRITGLTIEKVELRLPKIAFALPGTLFTDALRGRRIIELGRRGKYLLLHLDGDETLVIHLRMTGRLIHLRPEEREEPEAAHTHAVFFLDDGSLLRYTDVRQFGTLTLMTREAALRQPGKGRLGPEPLGQDFSFVDFRNALVKRKTKLKPLLLDQSFLAGLGNIYADEALARARLHPDRTADSLDDEESRRLYDCIRTVLQEGIDAKGTSFRDYVDGEGRKGEFQEKLWVYGRGGNPCRRCGGEILREKRAGRSTHFCPRCQK

mutM

Formamidopyrimidine-DNA glycosylase

277 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.855 kDa

MPELPEVATVITELKSCVLNKPVKQVKVHLDKVLKNTNVKQLNDALVNHSFVDIKRRGKYIIFCLSNGLFLVSHLRMEGKYFFEAKGSQFDLNHVLVEFLFQDGDQLNYHDTRQFGTFHLFNRYQFENARELNKLALDPLDQEFNHQAIFNKGHKSNKKIKTFILDQTNISGIGNIYADEILFASKIHPETLAKNLNLSQYQLICQNATDILKKAVEMKGTTIGTFTFKKDHTGGYQHFLKIHGKKGKQCQSCNTTIIKKKINGRGSYICEKCQIQR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.654 kDa

MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAEIFKEMLKGETIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTAEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.644 kDa

MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAKIFKEMLKGETIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAELTPQYLQERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTAEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.718 kDa

MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAEIFKEMLKGEKIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAEMTPQYLQERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTVEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.654 kDa

MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAEIFKEMLKGETIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTAEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.654 kDa

MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAEIFKEMLKGETIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTAEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.484 kDa

MPEMPEVETVRRTLTPLVKGKTIAKIIIWYPKIIVNNPDEFVEKLTNKKILKIDRYGKYLLFRFSDDLTMVSHLRMEGKYHLVTPDHPKGKHEHVEFVFTDGTALRYADVRKFGRMHLVETGTEKQTTGIRHLGPEPNTEEFSVEYFINALSRKKKNIKNTLLDQTVVCGLGNIYVDEVLWQSKIHPLSSAKSIPADKIVDLYHNINHTITVATKERGTTVHTYLDANGDIGGYQNMLQVYGHAGEECNNCGTILEKIKVNGRGTTFCPHCQVLYK

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.579 kDa

MPELPEVETVRRGLEKLVLNKKIKDIRVLYSKTIVNEESEFIEKLTNKTIKKIDRRGKYLLFRFSSDLTMISHLRMEGKYFVEPSTKEVEKHTHVVFDFTDGTSLRYNDVRKFGRMQLVKTGMEIQTAGLAKLGPEPKEKTFIVEDFSKNLKRRKKAIKNALLDQTIVAGLGNIYADEVLWMSKIHPETPANKLTEEEVKVLRDNIIKELALATEAGGTTIRSYTDAFRHSGGFQFSLHAYQRTGDPCERCGTPIQRIVVGQRGTHFCPKCQVVKS

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

29.959 kDa

MPELPEVEVTRLGLVDRIGGATVRALQLGKPLRWPIGVAPQQLAGQRIGELARRGKYIWMPLQDGSTPAGGLLWHLGMSGSLRFEAQLPPPGPHDHVELVTDRGSLRLTDPRRFGAVVWSPSLQAGCAARLLGGLGVEPLEDGFTASVLHQGLRGRRVAIKQALLAGDIVVGVGNIYCSEALFVAGIDPRLAAQRLSLARCERLVQAIRQVLRQALMAGGSTLRDFRDAHGMGGAFQLQAQVYDRADQPCRRCGALVRRIVQGQRATYFCPVCQRR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.484 kDa

MPEMPEVETVRRTLTPLVKGKTIAKIIIWYPKIIVNNPDEFVEKLTNKKILKIDRYGKYLLFRFSDDLTMVSHLRMEGKYHLVTPDHPKGKHEHVEFVFTDGTALRYADVRKFGRMHLVETGTEKQTTGIRHLGPEPNTEEFSVEYFINALSRKKKNIKNTLLDQTVVCGLGNIYVDEVLWQSKIHPLSSAKSIPADKIVDLYHNINHTITVATKERGTTVHTYLDANGDIGGYQNMLQVYGHAGEECNNCGTILEKIKVNGRGTTFCPHCQVLYK

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.579 kDa

MPELPEVETVRRGLEKLVLNKKIKDIRVLYSKTIVNEESEFIEKLTNKTIKKIDRRGKYLLFRFSSDLTMISHLRMEGKYFVEPSTKEVEKHTHVVFDFTDGTSLRYNDVRKFGRMQLVKTGMEIQTAGLAKLGPEPKEKTFIVEDFSKNLKRRKKAIKNALLDQTIVAGLGNIYADEVLWMSKIHPETPANKLTEEEVKVLRDNIIKELALATEAGGTTIRSYTDAFRHSGGFQFSLHAYQRTGDPCERCGTPIQRIVVGQRGTHFCPKCQVVKS

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

29.959 kDa

MPELPEVEVTRLGLVDRIGGATVRALQLGKPLRWPIGVAPQQLAGQRIGELARRGKYIWMPLQDGSTPAGGLLWHLGMSGSLRFEAQLPPPGPHDHVELVTDRGSLRLTDPRRFGAVVWSPSLQAGCAARLLGGLGVEPLEDGFTASVLHQGLRGRRVAIKQALLAGDIVVGVGNIYCSEALFVAGIDPRLAAQRLSLARCERLVQAIRQVLRQALMAGGSTLRDFRDAHGMGGAFQLQAQVYDRADQPCRRCGALVRRIVQGQRATYFCPVCQRR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.969 kDa

MPELPEVETVRRSLERTVSGKTISSVKVFHPKMIRGMEVAPFVDALKQERIERVERRGKFLLFTFDRFYLVSHLRMEGKYFPYPQAIEKDKHTHVIFRFTDGSELHYNDVRKFGTMELREKETAMSVPPLAQLEREPFDPTFTAEVLAENLIRKKRSPIKTSLLDQSIFLGLGNIYVDETLFAARVHPLTKAGALTLDDISRIHAAGVDVLAKAVESGGSTIRSYVSPTGKGEFQLQLAVYGQTGAPCPRCGTAIEKIKVGGRGTHFCPTCQQVAL

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.245 kDa

MPELPEVETVRRTLLQLVKNKTIADVDVGWPKMIKEPDDVERFIQLLKGQTIEDIGRRGKFLLFVLNDYVLVSHLRMEGRYGLYQPTDEKTKHTHVVFSFTDGSELRYADVRKFGTMHLFAKGAEHVAMPLAQLGVEPFSEQFTVELLEQAYAKTTRAIKTALLDQKTVVGLGNIYVDEALFHAGIHPERTASSLSKEEYHNLHKEIKRTLKEAIEAGGSSIKSYVNGQGEIGMFQQQLHVYGRKQQPCHHCDTAIEKTVVGGRGTHYCPNCQPRP

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 8-oxo-dGTP. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base.

Belongs to the FPG family.

31.002 kDa

MPELPEVETVRRTLTGLVKGKTIKSVEIRWPNIIKRPAEPEEFARKLAGETIQSIGRRGKFLLFHLDHYVMVSHLRMEGKYGLHQAEEPDDKHVHVIFTMTDGTQLRYRDVRKFGTMHLFKPGEEAGELPLSQLGPEPDAEEFTSAYLKDRLAKTNRAVKTALLDQKTVVGLGNIYVDEALFRAGVHPETKANQLSDKTIKTLHAEIKNTLQEAIDAGGSTVRSYINSQGEIGMFQLQHFVYGKKDEPCKNCGTMISKIVVGGRGTHFCAKCQTKK

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.891 kDa

MPELPEVETVVRTLRGLVMGKTIERVSVHLARIVRQPDDVEAFKSLLVGQTIQDIQRRAKFIQFFLNEDVLVSHLRMEGRYGVYQADDPVEKHTHVVFHFTDGTELRYRDVRQFGTMDLFPKGKETTIGPLAKLGVEPLDKSFTPEVLGKLLKGRSTKIKPLLLNQECIVGLGNIYVDESLFKAGIHPEKPAGKLTDKEVIRLHESIVSTLQEAVEQGGSSIKSYVNGQGEMGMFQQSLLVYGRKDEACTKCGAEIIRFVVGGRGTHICPDCQKNQ

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.442 kDa

MPEMPEVETVRRTLLPLIKGKTIEKVVLWYPTIVATDHDEFLKELPGKKIIGIDRYAKYLLIRLSDNLTIVSHLRMEGKYHLTTEDAPKDKHDHVEFVFTDKTALRYNDVRKFGRMQLIITGTERQVTGIKKLGPEPNTSEFSQQYLIDNLKKKHKNIKNVLLDQTTVAGLGNIYVDETLWQSKIHPLSIANKIPAKKVAGLWENINQTIALAIEKRGTTVHSYLDANGEVGGYQEMLQVYGHVGEECPRCGNIFEKIKVSGRGTTFCPHCQVIYK

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.434 kDa

MPEMPEVETVRRTLTPLVKGKTIAKINIWYPKIIVNDPAEFVKKLTNKRILKIDRYGKYLLFRFNDDLTMVSHLRMEGKYHLVSPDTPKGKHEHVEFIFTDGTALRYDDVRKFGRMHLVETGTERKTTGIRHLGPEPNTAEFNLKYFVDALSQKKKNIKNTLLDQTIVCGLGNIYVDEVLWKSKIHPLSSAKAIPADKVKNLYQNINHTIAIATKERGTTVHTYLDANGEIGGYQKMLQVYGHAGEECSSCGTILEKIKVNGRGTTFCPHCQVLYK

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.318 kDa

MPEMPEVETVRRTLIPLIKGKTIEKVILWYPKIVATDHEKFLSELPGKKIIDIDRYAKYLLIRLSDNLTIVSHLRMEGKYHLTTSDAPKDKHDHVEFIFTDGTALRYNDVRKFGRMQLILTGTERQTTGIGKLGYEPNSSEFTSEYLVNGLKRKKKNIKNTLLDQSVVAGLGNIYVDEVLWRTKIHPLSQANKIPAEKVMELHDQINQIITEAIKLQGTTVHSFLNANGQVGGFQSKLQVYGHVGEPCPVCGTKFEKIKVNGRGTTFCPHCQVIYK

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.773 kDa

MPELPEVETLKNSLKDKLIELIIENVELKRDNLRYKLSPLLASEISNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQPSNYETKKHDHVIFDLSNGEKLIFNDTRRFGMIYNFKTNFLEKELFNNLGVEPLSDSLTLEYLKSKLITRKIPIKNLIMDNRIIVGVGNIYASESLYLARIHPDKLGSNLRDDEIESLIKSIREVLAKAITAGGTTLKDFVNGDNKPGYFTQQLTVYGRERQNCLNCSSTIIKTKHSGRSTFYCRTCQYSEFT

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.658 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGFAEMLRSREVLRVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPNDAPPPAPAKHDHVDWIFDEFVLRFRDPRRFGAVLWHPRDAGDVHAHPLLASLGVEPFSAAFSGALLFGRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGAPIRQIVQGQRSTYFCPNCQR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.658 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGFAEMLRSREVLRVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPNDAPPPAPAKHDHVDWIFDEFVLRFRDPRRFGAVLWHPRDAGDVHAHPLLASLGVEPFSAAFSGALLFGRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGAPIRQIVQGQRSTYFCPNCQR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.658 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGFAEMLRSREVLRVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPNDAPPPAPAKHDHVDWIFDEFVLRFRDPRRFGAVLWHPRDAGDVHAHPLLASLGVEPFSAAFSGALLFGRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGAPIRQIVQGQRSTYFCPNCQR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.658 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGFAEMLRSREVLRVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPNDAPPPAPAKHDHVDWIFDEFVLRFRDPRRFGAVLWHPRDAGDVHAHPLLASLGVEPFSAAFSGALLFGRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGAPIRQIVQGQRSTYFCPNCQR

mutM

Formamidopyrimidine-DNA glycosylase

276 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.709 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPADFAEMLRSREVLGVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPNDAPPPAPAKHDHVDWVFDEFVLRFRDPRRFGAVLWHPRDAGDVRAHPLLASLGVEPFSAAFSGALLFKRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGAPIRQIVQGQRSTYYCPNCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.223 kDa

MPELPEVETTRRGIEPALVGKRLCGVVVRQPQLRWPIPVKTLEKELVGQVIQQVARRAKYLLWRCPQGTLLVHLGMSGSLRIVPEHTPPAKHDHVDWVMEGGQMVRLHDPRRFGAVVWIPVTSPEEEHPLLAKLGPEPLHRSLNGRYLHQGSRGRQLAVKNYIMDQSVVVGVGNIYASEALFRAGIAPAQAAGKVGLGRYRALACAIKAVLGDSIEQGGTTLRDFIGSDGKPGYFVQSLNVYGRAGKACPKCGTTIEKQVLGQRSSYYCPQCQRA

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.223 kDa

MPELPEVETTRRGIEPALVGKRLCGVVVRQPQLRWPIPVKTLEKELVGQVIQQVARRAKYLLWRCPQGTLLVHLGMSGSLRIVPEHTPPAKHDHVDWVMEGGQMVRLHDPRRFGAVVWIPVTSPEEEHPLLAKLGPEPLHRSLNGRYLHQGSRGRQLAVKNYIMDQSVVVGVGNIYASEALFRAGIAPAQAAGKVGLGRYRALACAIKAVLGDSIEQGGTTLRDFIGSDGKPGYFVQSLNVYGRAGKACPKCGTTIEKQVLGQRSSYYCPQCQRA

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

29.581 kDa

MPELPEVETVMRGLAAKLEGRRLARVVLARPDLRWPIPEGFVQFLSGARVEGFRRRGKYMFMRLDRALSVLIHLGMSGRMTIDSAPLPHQHLTLETDDGAVIGFVDPRRFGALDLVATAAEDSHRLIAGLGPEPLDDAFSPATLASALEGKKTPIKAALLDQSVVAGLGNIYVSEALFRAGILPHRLAGTIGRGRAGRLVPAIKATLTDAIAAGGSSLRDYVQPSGELGYFQHAWKVYDRAGQPCERCPGPAACAGISRTVQSGRATYFCARTQK

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.315 kDa

MPELPEVETVCRRLRPAVSGKTIQSVDVLDPKIIRGLDPEEWVHHLIGETITDVERRGKFILFKLTNGYLVSHLRMEGKFFPYETATEPVKHTHVVITFTDQSTLHYNDVRKFGTMELRTNETIHTTPPLSLLAYEPFDERVTTEALHRRLERMKTRAIKTALLDQSIFVGLGNIYVDETLFRAGVHPTRPAASLSREEVDRVRTEAVAVLNEAIERGGSTIRSYADPDGATGTFQERLYVYGQTGEPCRRCGHEIEKMKLGGRGTHYCPHCQQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.317 kDa

MPELPEVETVRRTLAGLVRGKTIDAVDVRWTKIIKRPEEPEEFARLLAGQTIQSIGRRGKFLLFHLDDCVMVSHLRMEGKYGLHQNDEPLDKHVHVIFRFTDGSELRYRDVRKFGTMHLFKPGEELTELPLRQLGPEPFSSEFTADYLRERLKKTNRSVKTALLDQRTVVGLGNIYVDEALFRAGIHPEATANKLTKKQTVLLHKEIIQTLKEAVEAGGSTVRSYINSQGEIGMFQLKLFVYGRKDEPCKKCGSPIEKTVVGGRGTHFCIKCQKK

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.633 kDa

MPELPEVETTRRGIDPVITGQTLRRLVVREPRMRWPIPADLPSLLTDRPVLATGRRGKYLLLRFEHGVQIVHLGMSGSLRRVAMDEAPRKHDHVDWVFDHAILRLHDPRRFGAVLWHPNTDGPVEAHPLLIGLGIEPFDPRFDGKWLHDHFRDKRVAVKQALLAGHAVVGVGNIYASECLFRAGIDPRTPAGKLSRPRCERLAQAVRATLADALASGGSTLRDYVGASGEPGAYFAIHAAVYERAGLACRVCGTPIRRLVQGQRATYFCPHCQKR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.427 kDa

MPELPEVETTRRGIDTVITGRTLRRLVVREARMRWPIPPALPDLLAGRTVLECGRRGKYLLLRFDHGVQIVHLGMSGSLRRVPEQEAPRKHGHVDWVFDHAVLRLHDPRRFGAVLWHPDEAGPIAAHPLLARLGIEPFDPRFDGRWLHAYFRGRRVAIKQALLAGDAVVGVGNIYASESLFRAGIDPRTAAQRVSAARCDRLAAAIRATLSDALDSGGSTLRDYVGASGEPGAYFAIHAAVYERAGLPCRVCGAPIRRLVQGQRATYFCPSCQKR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.349 kDa

MPELPEVETTRRGIDAVITGKTLRRLLVRESRMRWPIPADLPGLLSGRAVLECARRGKYLLLRFEHGTQIVHLGMSGSLRSVPAGEAPRKHDHVDWIFDHATLRLHDPRRFGAVLWHPDTAGPIAAHPLLARLGIEPFDPRFDGAWLHSQFRNRAIAVKQALLAGDAVVGVGNIYASESLFRAGIDPRTPARRISRARCARLADMVRATLADALASGGSTLRDYVGASGQPGSYFEIHAAVYERAGLPCRVCGTPIRRLVQGQRATYYCPSCQKR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.515 kDa

MPELPEVETTRRGIDTVITGRTLRRLVVREARMRWPIPPALPDLLAGRTVLECGRRGKYLLLRFDHGVQIVHLGMSGSLRRVPEQEAPRKHDHVDWVFDHAVLRLHDPRRFGAVLWHPDEAGPIAAHPLLARLGIEPFDPRFDGRWLHAYFRGRRVAIKQALLAGDAVVGVGNIYASESLFRAGIDPRTAAQRVSAARCDRLAAAIRATLSDALDSGGSTLRDYVGASGEPGAYFAIHAAVYERAGLPCRVCGTPIRRLVQGQRATYFCPSCQKR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.614 kDa

MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPGTASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.676 kDa

MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKSCPRCGQAIVKLKVGGRGTHICPKCQKKRP

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.363 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPAAGVPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHAREAGDVHAHPLLASLGVEPFSPAFTGALLHARTRGRTVSVKQALLAGDMVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGLPCRVCGTPIRQIVQGQRSTYFCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.39 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPAAGVPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHPREAGDVHAHPLLASLGVEPFSPAFTGALLHARTRGRTVSVKQALLAGDMVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGQPCRVCGTPVRQIVQGQRSTYFCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.39 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPAAGVPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHPREAGDVHAHPLLASLGVEPFSPAFTGALLHARTRGRTVSVKQALLAGDMVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGQPCRVCGTPVRQIVQGQRSTYFCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.42 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTAMLRWPVPAGLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPAAGVPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHPREAGDVHAHPLLASLGVEPFSPAFTGALLHARTRGRTVSVKQALLAGDMVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGQPCRVCGTPIRQIVQGQRSTYYCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.577 kDa

MPELPEVEVTRRGIEPFVAGRRVERVDVRTEMLRWPVPAGLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPADGLPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHPREAGDVHAHPLLASLGVEPFSPAFTGALLHARTRGRTVSVKQALLAGDMVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFVYDRAGQPCRVCNTPIRQIVQGQRSTYFCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.404 kDa

MPELPEVEVTRRGIAPFVAGRRVERVDVRTAMLRWPVPAGLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPAGGVPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHSREAGDVHAHPLLASLGVEPFSPAFDGALLHRRTRGRTVSVKQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLAEAVRATLADAIDRGGSTLRDFVGSNGESGYFQLDCFVYDRAGEPCRVCGTPIRQIVQGQRSTYFCPTCQR

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.856 kDa

MPELPEVETTLRGIAPHIEGKTVEAVILRQLKLRWQINPDLGEILSGRQVLSCGRRAKYLIVRFQTGILLIHLGMSGSLRIFTPSDGRIGRPDRHDHVDIVFSDGTVMRYRDPRKFGAILWYEGIEERHPLLEKLGPEPLSEAFCTDYLYAGLKAQKRAVKLALMDNTVVVGVGNIYANESLFRAGISPHRPANRLKKKECAVLVETVKAVLQRAIETGGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCLRCGGLVVKETLGQRGTFYCTNCQK

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

30.904 kDa

MPELPEVETTLRGIAPHIEGKTVEAVVLRQLKLRWQINPDLGEILSGRQVLSCGRRAKYLIVRFQTGILLIHLGMSGSLRIFTPSDGRIGRSDRHDHVDIVFSDGTVMRYRDPRKFGAILWYEGIEEHHPLLEKLGPEPLSEAFCTDYLYVRLKAQKRAVKLALMDNAVVVGVGNIYANESLFRAGISPHRPANRLKKKECALLVETVKAVLRRAIETGGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCPQCGGLVVKETLGQRGTFYCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

30.856 kDa

MPELPEVETTLRGIAPHIEGKTVEAVVLRQLKLRWQINPDLGEILSGRQVLSCGRRAKYLLIRFQTGVLLIHLGMSGSLRIFTPSDGRIGRPDRHDHVDIVFSDGTVMRYRDPRKFGAILWYEGIEEHHPLLEKLGPEPLSEAFCADYLYARLKAQKRAVKLALMDNAVVVGVGNIYANESLFRAGISPHRPANRLKKKECALLVETVKAVLQRAIETGGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCPRCGGLVVKETLGQRGTFYCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.702 kDa

MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRL

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.676 kDa

MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKSCPRCGQAIVKLKVGGRGTHICPKCQKKRP

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.717 kDa

MPELPEVETVRRGLKALVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAVLLSSKKTIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNTLGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.686 kDa

MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALTLPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP

mutM

Formamidopyrimidine-DNA glycosylase

275 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.993 kDa

MPELPEVQTIVDYLNHHVLDIFIKKTIVHLPKILKNKTPQEFEKLLINHKIVKIKRLGKYLLFFLSNNLVLSVHLRMEGKFYYQAKEEWFNLAHTHIIIEFNNGMQLRYNDTRQFGTFHIYEQQSFLDSKELKKIALDPLDNNFSAQYLYEKLKKSNKAIKTALLDQSVVSGIGNIYADEILFAAKIFPTILAKNLTLKNYEKITKEAQRILLLSIKNKGTTIHTYKFGNDETGLFQKMLLVHTHAKEPCQICGTIIQKTKVNGRGTYYCPNCQN

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.114 kDa

MPELPEVETVKRTLTELVIGKTIAGITVKWANIIKEPADVLEFETLLMNQTIRSIRRRGKFLLFEFDDIVMVSHLRMEGRYGLYEKEEPLPPHTHVIFHFTDGEELRYQDVRKFGTMHLFPKGSEEKVLPLAHLGVEPFSEQFTSELLMNAFQKTNRKIKVALLDQKTVVGLGNIYVDEALFRARIHPERLAHSLSKEEMAVLHKAIVSTLEEAVEMGGSSIKSYVNGQGEMGMFQQKLGVYGRKNEPCRQCGTDILKTVVGGRGTHFCPNCQL

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

30.999 kDa

MPELPEVETVRRTLAELVIGKTIEQVDVGWAKMIKRPDDVDQFKWLLKGQTIRSMGRRGKFLLFHLDDYTLVSHLRMEGRYGLYQQNESVAKHTHVRFVFGDGTELRYQDVRKFGTMHLFQSGREQMEPPLAKLGVEPFSDQFSAKLLTERLSKTSRKIKSALLDQGIIVGLGNIYVDEALFRARIHPERLAKDVTVAEVKILHQAILNTLTEAVNLGGSSIKSYVNGQGEMGMFQQRLDVYGRKGETCRQCGTPITKTVVGGRGTHFCSVCQK

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.892 kDa

MPELPEVETVRRGLNRLVSGATIASIEVFWPKIINNDVDSFKQRLANQTIQTIDRRGKYLLFRFSNGLTMVSHLRMEGKYNVVPRGEDQGKHTHVIFHLTDDRDLLYNDTRKFGRMTLVPTGEENTVAGLRTIGPEPVAEQLTLAYMTATFGKSKKMIKPLLLDQSKIAGIGNIYADETLWMSKIHPMRPANSLTTDEIATLRQNIIDEMAMAIKGHGTTVHSFSTAFGEAGQFQNHLHVYGREGEPCERCGTIIEKIKVAQRGTHFCPLEQRL

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.812 kDa

MPELPEVETTKQGIKPHLEGRIITTAQVRNRKLRLPVPLNLNELCEGKHITAITRRGKYILLHMDKGYILIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFCDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.827 kDa

MPELPEVETTKQGIKPHLEGRMITAVQVRNRKLRLPVPLNLNELCQGKHITAITRRGKYILLHMDKGYLLIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFCDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.816 kDa

MPELPEVETTKQGIKPHLEGCMITSVQVRNQKLRLPVPLNLNELCEGKHITAITRRGKYILLHMDKGYLLIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFRDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.892 kDa

MPELPEVETVRRGLNRLVSGATIASIEVFWPKIINNDVDSFKQRLANQTIQTIDRRGKYLLFRFSNGLTMVSHLRMEGKYNVVPRGEDQGKHTHVIFHLTDDRDLLYNDTRKFGRMTLVPTGEENTVAGLRTIGPEPVAEQLTLAYMTATFGKSKKMIKPLLLDQSKIAGIGNIYADETLWMSKIHPMRPANSLTTDEIATLRQNIIDEMAMAIKGHGTTVHSFSTAFGEAGQFQNHLHVYGREGEPCERCGTIIEKIKVAQRGTHFCPLEQRL

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.812 kDa

MPELPEVETTKQGIKPHLEGRIITTAQVRNRKLRLPVPLNLNELCEGKHITAITRRGKYILLHMDKGYILIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFCDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.827 kDa

MPELPEVETTKQGIKPHLEGRMITAVQVRNRKLRLPVPLNLNELCQGKHITAITRRGKYILLHMDKGYLLIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFCDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.816 kDa

MPELPEVETTKQGIKPHLEGCMITSVQVRNQKLRLPVPLNLNELCEGKHITAITRRGKYILLHMDKGYLLIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFRDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.164 kDa

MPELPEVETTKTSLFPLLNQKVLSVEVRNPSLRWPIPDNVQKLVGQRLIGLNRRSKYILAEFEQDQMLWHLGMSGSFRLCQPNDELRKHDHLIIQFEDQQLRYHDPRRFGCILWLNPETQGKLIDTLGPEPLSTDFHAEYLASKLKNKSVGIKIALMDNHVVVGVGNIYATESLFNVGIHPAQPAGDLTMQQIEKLVVEIKRILKSAIDLGGSTLRDYSNAMGENGYFQQTLLAYGRAREMCVNCETTLENLKLGQRASVFCPQCQPLKKLRKP

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.303 kDa

MPELPEVETVKRGLIKTIIDKKIFDIEINTDKLRYPIDKDQLVKIKNKVVKEIQRRGKHLIIFIEDDLQLIIHLGMSGIIKVIDSTNYNKIKHDHIVVTLSDNLSLVYNDPRKFGYWLVNTNHTPLEHRVLVSHGVEPLTADFNSDYLVSKLKQTSRKIKQTIMDNNIVVGVGNIYASEALFDSNILPTRASNTITKKEAANLVSSIKKILEKAITQGGTTLKDYKNTEGKPGYFTQQLNVYGRNEQQCYVCNTKIQSLVIAQRNTFFCKKCQK

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.619 kDa

MPELPEVETIRRTLLPLIVGKTIEDVRIFWPNIIRHPRDPEAFAARMIGQTVRGLERRGKFLKFLLDRDALISHLRMEGRYAVASALEPLEPHTHVVFCFTDGSELRYRDVRKFGTMHVYAKEEADRRPPLAELGPEPLSPAFSPAVLAERAVKTKRSVKALLLDQTVVAGFGNIYVDESLFRAGILPGRPAASLSSKEIERLHEEMVATIGEAVMKGGSTVRTYVNTQGEAGAFQHSLFVYGRKGEPCKRCGTPIEKTVVAGRGTHYCPRCQR

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.443 kDa

MPELPEVETCLRGIEPYLAGQTIQQIVIRTPKLRWPISAELCAMSGAKILALSRRAKYLIIHTERGDILVHLGMSGSLTLLNSSQPTKASKHDHVDLITEAGIILRYNDPRKFGAWLWAKQAENYPLITKLGPEPLSDTFTSDYLFKKSRNKTVAVKNFIMNNDIVVGVGNIYASESLFMAGVHPELAAQNLTEKQCVQLRNVIQAVLTKAIIQGGTTLKDFTQPDGKPGYFAQVLQVYGRKGEECRECGTLIQAKVIGQRNSYFCPDCQPLPK

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.222 kDa

MPELPEVEVISRGLAESLEGKTIESVKILNHSSVKMPWYLFSSRVAGEKITRIHRRAKLLIMDLGDDLHITFHLKMTGRVLAHEGPTTPEPHTRIVFGLTDGGSIEFHDTRKFGEVRALNNEELQEWDFYKNLGPEPLEVTAEELAERITGRKAQIKGLLLNQSVVAGCGNIYADESLFRSGIHPKAKASDLSNESLVKLFTELQAVLKQAIQENGSSIRDYVDAGGDAGGFQNSFKVYGKKGEPCPDCGKIFEGATVAGRTSTFCSNCQKMKD

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.128 kDa

MPELPEVETSRRGIEPHLVGNILHYAIVRNSKLRWPVSEKIKTLLDEPILSVKRRAKYLLIELNQGWIIVHLGMSGSVRILPEEQPEEKHDHIDLVFRDGKVLRYTDPRRFGAWLWCEDLATSSVLAHLGPEPLSAQFNAQYLYQQSKNKKIAIKPWLMDNKLVVGVGNIYANEALFSSGIMPDRKASSLTEQECDVLVNAIKTVLTRSIEQGGTTLKDFLQSDGKPGYFAQELFVYGRKDKACLICGHTIESIKQGQRSTFFCRHCQHGEITD

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.486 kDa

MPELPEVETSMRGISPYLVGQKIKEIIVRQPKLRWAVSSELSTMQGATIIEIYRRAKYLIIQTDKGDILVHLGMSGSLGILSVKENKAIDKHDHIDLITENGVILRYNDPRKFGTWLWAEQAETAELLANLGPEPLSEAFTSGYLFEKSRNKTVAVKNFIMNNAIVVGVGNIYACESLFMAGIHPELAAQNLTAKQCERLVTVIKEVLTKAIIQGGTTLKDFIQPDGKPGYFAQVLQVYGRKGEECNDCGSIIEAKVIGQRNSFYCPKCQRLPK

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.189 kDa

MPELPEVETIKRTLTPCLREQKIARVEVYHPGVIAAPDPETFSRLLAGRIITGLDRRGKYLLVHLSGEYCLVVHLRMTGRLVFTEGAAPLAPHTHVVFSLAGGPSLRFVDTRRFGRLYLAAKAEVETLPGLRDLGPEPLDPAFDALALAAILAGRRRPIKQVLLDQRLVAGIGNIYADEMLFAAGIDPRRPAASLNHEEVARLRGAMQRVLEQGIANRGTSIRDYVDGSGRQGSNQEHLQVYGRTGRPCPRCGQPLERVRLGGRSTHFCPRCQV

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.216 kDa

MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRELPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGGTLVYEDVRKFGTMELLVPDLLDVYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.172 kDa

MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRELPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGGTLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD

mutM

Formamidopyrimidine-DNA glycosylase

274 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.937 kDa

MPELPEVKTVILHLKKLILDKTISKIEIFIPKMIKEISSEEFKKYLENETIFNIENEGKFIVFFLSNNKIMLSHLRMEGGYNFYSKKRQKEIHDRLIFHFTDGSSLHYHDSRMFGTFHFRNSENYLKIKPLSLVAPVPWKIDLDEFFKLLKRKKTAIKKILLDQQIIAGLGNIYVDETLFASKVHPEFKANQLSLEQVKLILKNATRILQESTKLGGSSIRSYTSLNEKEGSFQNFLQVHTKFNKPCPNCGELIQKIKLGGRGTYFCKKCQQLN

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.429 kDa

MPELPEVETSRLGITPHLQGQTIKAIVVRTDKLRWPIPQELQKLVGQRVQSIRRRAKYLMIDTPEGSAIIHLGMSGSLRVLDEEVPSAKHDHVDLVLENGKVLRYNDPRKFGAWLYSEVGVAHQVLSKLGPEPLTNEFNSEYFAEKAKNKKTVVKQFIMNNAVVVGVGNIYASESLFMAQIHPKTPVGSLKASQITVLVAEIKKVLETAIKQGGTTLKDFNQVDGKPGYFAQELKVYGRAGKECPVCSSKIEEEKIGQRNSFWCGKCQFLAED

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.31 kDa

MPELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKTIQGISRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFADGQLIYADVRKFGTWELISTDQVLPYFLKKKIGPEPTYDEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKETNQLIESSIHLLHDSIIEILQKAIKLGGSSIRTYSALGSTGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPVCQQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.673 kDa

MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVATPPDEFVHMLVGQEIEAVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDENEEVTKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGESETKSIKKLGPEPLTPAFTLADFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVHPERAANSLSDKEINRIFEATKSIMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTGEPCVICGTPIEKIKLNGRGTHFCPHCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.789 kDa

MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVSTPPDEFVHMLVGQEIEGVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDEKEEVSKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGEGETRSIKKLGPEPLTQAFTSTDFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVRPERAANSLSDKEIKRIFEATKSIMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTDEPCVVCGKPIEKIKLNGRGTHFCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.772 kDa

MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVSTPPDEFVHMLVGQEIEGVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDENEEVSKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGEGETRSIKKLGPEPLTQAFTLTDFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVRPERAANSLSDKEIKRIFKATKSIMTEAVALGGSTVRTYVNSQGKLGQYQNKLKVYGKTDEPCVVCGTPIEKIKLNGRGTHFCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.31 kDa

MPELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKTIQGISRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFADGQLIYADVRKFGTWELISTDQVLPYFLKKKIGPEPTYDEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKETNQLIESSIHLLHDSIIEILQKAIKLGGSSIRTYSALGSTGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPVCQQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.673 kDa

MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVATPPDEFVHMLVGQEIEAVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDENEEVTKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGESETKSIKKLGPEPLTPAFTLADFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVHPERAANSLSDKEINRIFEATKSIMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTGEPCVICGTPIEKIKLNGRGTHFCPHCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.789 kDa

MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVSTPPDEFVHMLVGQEIEGVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDEKEEVSKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGEGETRSIKKLGPEPLTQAFTSTDFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVRPERAANSLSDKEIKRIFEATKSIMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTDEPCVVCGKPIEKIKLNGRGTHFCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.772 kDa

MPEMPEVENVRATLQELVPGKKIDQVIVRVPKMIVSTPPDEFVHMLVGQEIEGVRRRGKFLLFDLTNCTILSHLRMEGKFRLMDENEEVSKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGEGETRSIKKLGPEPLTQAFTLTDFATGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVRPERAANSLSDKEIKRIFKATKSIMTEAVALGGSTVRTYVNSQGKLGQYQNKLKVYGKTDEPCVVCGTPIEKIKLNGRGTHFCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.737 kDa

MPELPEVETSLRGVEPYLHGKIIKQIVVRTQKLRWAVSDELQHMQGAKIVALSRRAKYLILHTTQGDILIHLGMSGSLGILQENQQPAGKHDHVDLITQDGMVLRYNDPRKFGCWLWTKNAEQHELITRLGPEPLSESFTAAYLFARSRNKTVAVKNFIMNNDIVVGVGNIYACESLFMAELHPELAAQNLTEKQCERLVKVIKEVLAKAIIQGGTTLKDFIQPDGKPGYFAQVLQVYGRKDEACNDCGTIIEAKVIGQRNSYFCPHCQMLPR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.588 kDa

MPELPEVETSLRGVEPYLHGKIIKQIVVRTQKLRWAVSDELQHMQGAKIVALSRRAKYLILHTTQGDILIHLGMSGSLGILQENQQPAGKHDHVDLITQDGMVLRYNDPRKFGCWLWTKNAEQHELITRLGPEPLSESFTAAYLFARSRNKTVAVKNFIMNNDIVVGVGNIYACESLFMAGLHPELAAQNLTEKQCERLVKVIKEVLAKAIIQGGTTLKDFIQPDGKPGYFAQVLQVYGRKGEACNDCGTIIEAKVIGQRNSYFCPHCQILPR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.649 kDa

MPELPEVETSLRGVEPYLHGKIIKQIVVRTQKLRWAISDELQHMQGAKIVALSRRAKYLILHTTQGDILIHLGMSGSLGILQENQQPAGKHDHVDLITQDGTVLRYNDPRKFGCWLWTKNAEQHELITRLGPEPLSESFTAAYLFARSRNKTVAVKNFIMNNDIVVGVGNIYACESLFMAGLHPELAAQNLTEKQCERLVKVIKEVLAKAIIQGGTTLKDFIQPDGKPGYFAQVLQVYGRKDEACNDCGTIIEAKVIGQRNSYFCPHCQMLPR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.869 kDa

MPELPEVETIRRSLSQHILERRIEEILIRWPGAVEGYEEKTFADAVRGLKFQSIERRGKYLLFTLEEGWSFIAHMRMTGRMVYHAQSQEPEKHTHVVLKLSSGEIHFTDTRKFGRLQLVRTEERLQQPSLARLGPEPLEEGFSAAELGRRLAPRKLAIKAALLDQTLVAGIGNIYADEALFRAGIAPERCANSLTKEEIEKLYPAICQVLEEGIAANGTSFRDYQDANGERGDFQKELKVYGRGGEPCKECGHTLVRIRLAGRSTVFCPCCQV

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.869 kDa

MPELPEVETIRRSLSQHILERRIEEILIRWPGAVEGYEEKTFADAVRGLKFQSIERRGKYLLFTLEEGWSFIAHMRMTGRMVYHAQSQEPEKHTHVVLKLSSGEIHFTDTRKFGRLQLVRTEERLQQPSLARLGPEPLEEGFSAAELGRRLAPRKLAIKAALLDQTLVAGIGNIYADEALFRAGIAPERCANSLTKEEIEKLYPAICQVLEEGIAANGTSFRDYQDANGERGDFQKELKVYGRGGEPCKECGHTLVRIRLAGRSTVFCPCCQV

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.8 kDa

MPELPEVETVRRSLEQELVGRYFVALRSLGWPKIVDTHSPELFAEAIAQRQIQQVQRRAKYLLIELDNHETLIVHLRMTGQMLVVAADEPADRHTHVVVALDNGRELRFHDPRKFGRWSLVDRSGVAALNQRLGPEPLGDDFTLDDFAQRLSRKATKIKPTLLDQSVLAGVGNIYADEALWLAKIHPLRSANSLNANEIAELFEAIKTVLRNSIEHRGTTLVNYRDAYGASGENQYHLEAYGRTGEPCRRCGTPIERIVVAQRSTHICPVCQA

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.353 kDa

MPELPEVEVTRRGVAPYLEGQVVSGVVLRHTGLRWPFPAALSQTLAGRTIRSTGRRGKYLLIHFDHGTLIVHLGMSGHIRILPLGVPPQKHDHFDMTVGNQVLRLTDPRRFGAVLWHAAEEGAVDQHLLLRTLGVEPLEGLFTAQWLYRQTRSRRSAIKQVLLAGDIVVGVGNIYASESLFQAGINPKTQAHRIGLQRYERLAQAIREILAAAIAQGGSTLKDFIGVNGQSGYFQQNYFVYARTGEPCRICNAPVRQIVQGQRSTFYCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.445 kDa

MPELPEVEVTRRGVAPHLEGQVITGVALRHTGLRWPFPATLSQTLAGRTVRSTGRRGKYLLIHFDHGTLIIHLGMSGHLRILPSDVPPKKHDHFDLEIGPQLLRLTDPRRFGAVLWHAAEDGSIENHLLLRTLGVEPLEAAFSAQWLYQQTRNRSSAIKQVLLAGDIVVGVGNIYASESLFQARINPKTPAHRIGLARYERLAEAIRQILAAAIEQGGSTLKDFIGVNGQSGYFQQNYFCYARTGEPCRICKTPIRQIVQGQRSTFYCPNCQK

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.043 kDa

MPEMPEVETVRRTLRPLVVGKTIDHVDIWYDKVITGDPETFKRELKGKTFTAVDRYAKFLLFRLGDLTVVSHLRMEGKYHLTTWDAPVDKHEHLQFAFTDGSSLRYADVRKFGRLQLVETGTEFQVTGLKNLGVEANSPEFRLDYFEKGLKKRSMNIKSLLMSQTLVAGLGNIYVDEVLWQSRINPLTPANELTKDQVKQLHSAINETIEEATKYGGTTVHSFLNAEGGAGHYQEKLKVYGKEGQPCPRCGEDFVKIKISGRGTTYCLHCQKR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.087 kDa

MPEMPEVETVRRTLRPLVVGKTIDHVDIWYDKVITGDPETFKRELKGKTFTVVDRYAKFLLFRLGDLTVVSHLRMEGKYHLTTWDAPVDKHEHLQFAFTDGSSLRYADVRKFGRLQLVETGTEFQVTGLKNLGVEANSPEFRLDYFEKGLKKRSMNIKSLLMSQTLVAGLGNIYVDEVLWQSRINPLTPANELTKDQVKQLHSAINETIEEATKYGGTTVHSFLNAEGGAGHYQEKLKVYGKEGQPCPRCGEDFVKIKICGRGTTYCLHCQKR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.291 kDa

MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLTTEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFFNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGIGNIYASESLHLARIHPDKSGNDLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.103 kDa

MPELPEVETLKNSLESKLIGLVIKKVEFKRDNLRYKLSADLADQIVNTNIINVRRRAKYLIIDFNNNHSLIVHLGMSGRFTLQPNNYEVKKHDHVVFNLSNNEKLIFNDTRRFGMIYSFHTELLEKDFFANLALEPLSDSFELQYLKSKLMNKKVPIKNLLMDNRIVVGVGNIYASESLHLAKIHPDKFGKDLNDDEIKNLIAAVKNVLSKAIIAGGTTLKDFVNGDNKPGYFTQQLMVYARDGQECLSCSSSIIKTKHSGRSTFYCKSCQKA

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.103 kDa

MPELPEVETLKNSLESKLIGLVIKKVEFKRDNLRYKLSADLADQIVNTNIINVRRRAKYLIIDFNNNHSLIVHLGMSGRFTLQPNNYEVKKHDHVVFNLSNNEKLIFNDTRRFGMIYSFHTELLEKDFFANLALEPLSDSFELQYLKSKLMNKKVPIKNLLMDNRIVVGVGNIYASESLHLAKIHPDKFGKDLNDDEIKNLIAAVKNVLSKAIIAGGTTLKDFVNGDNKPGYFTQQLMVYARDGQECLSCSSSIIKTKHSGRSTFYCKSCQKA

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.471 kDa

MPELPEVETLKNSLKDKLIGLIIKNIELKRDNLRYNLSPLLTTEILNTNILNVRRRAKYLIIDFGNYYSLVIHLGMSGRFTVQPANYKIQKHDHVIFDLNNCEKLIFNDTRRFGMVYSFKTNFLEEKFFYNLGIEPLSDLLTLEYLKSKLITRTIAIKNLIMDNKIIVGVGNLYASESLHLARIHPHKLGRNLKDDEIENLIKSIREVLTKAITAGGTTLKNFVNGDSKPGYFTQQLRVYGREGQKCFNCSSTILKTKNSGRSTFYCKTCQYT

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.2 kDa

MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLATETLNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFLNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGNNLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.274 kDa

MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLATEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMNGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFFNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGNDLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.247 kDa

MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLATEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFFNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGNDLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.247 kDa

MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLATEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFFNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGNDLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.329 kDa

MPELPEVQLAADSLGVQIVGARIVRVERLDWTRMVETPSPDEFITLLAGRQVHGWGRRAKWILLFLDGGWTLALHLRMSGSLTVQPADAPPDKHTHLVLRLDDGRQVFFRDPRKFGRARLLDADGRAALDAAHGDEPLSNAFTVERLAELLRGRKRAIKPLLLDQAVIAGIGNIYADEALWRARIHPLRPASDLSADEVAALHDGIRAALRQALTNGGSTLRDYRNSYGTRGTNQDHFNAYDREGQPCPRCGATIIKTVVAQRGTHYCPECQR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.115 kDa

MPELPEVETVRRGLEKLLLGRTILSLEVKVPKMIKTSYDSFLHDLPGQTIQAMRRRGKYLIFDFGQLIIISHLRMEGKYLLFTDQVPDNKHFHLFFKLDDGSTLVYQDVRKFGTFDLLDRKQEEAYFTRKELGPEPTKKTFKYVPFERALMHSGKSIKPLLLEQKLVAGLGNIYVDEVLWAAKVHPETPANKLSKAAMKRVHDQTIAILQLGIAKGGSTIRTYRNALGEDGTMQNYLQVYGKTGQPCPRCASMIVKIKLGGRGTHLCPHCQKR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.115 kDa

MPELPEVETVRRGLEKLLLGRTILSLEVKVPKMIKTSYDSFLHDLPGQTIQAMRRRGKYLIFDFGQLIIISHLRMEGKYLLFTDQVPDNKHFHLFFKLDDGSTLVYQDVRKFGTFDLLDRKQEEAYFTRKKLGPEPTKKTFKYVPFERALMHSGKSIKPLLLEQKLVAGLGNIYVDEVLWAAKVHPETPANKLSKAAMKRVHDQTIAILQLGIAKGGSTIRTYRNALGEDGTMQNYLQVYGKTGQPCPRCASMIVKIKLGGRGTHLCPHCQKR

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.034 kDa

MPELPEVETVRKGLERLVVNQEIASITIKVPKMVKTDLNDFMISLPGKTIQQVLRRGKYLLFDFGEMVMVSHLRMEGKYLLFPNKVPDNKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSKGLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRILTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCPRCQCL

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.034 kDa

MPELPEVETVRKGLERLVVNQEIASITIKVPKMVKTDLNDFMISLPGKTIQQVLRRGKYLLFDFGEMVMVSHLRMEGKYLLFPNKVPDNKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSKGLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRILTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCPRCQCL

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

31.034 kDa

MPELPEVETVRKGLERLVVNQEIASITIKVPKMVKTDLNDFMISLPGKTIQQVLRRGKYLLFDFGEMVMVSHLRMEGKYLLFPNKVPDNKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSKGLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRILTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCPRCQCL

mutM

Formamidopyrimidine-DNA glycosylase

273 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

30.875 kDa

MPELPEVETVRRGLEHLIVGKKIVSVEVRVPKMVKTGVEDFQLDILGQTFESIGRRGKYLLLNLNRQTIISHLRMEGKYLLFEDEVPDNKHFHLFFGLDGGSTLVYQDVRKFGTFELLPKSQVEAYFVQKKIGPEPNAKDFKLKPFEEGLAKSHKVIKTLLLDQHLVAGLGNIYVDEVLWAAKVDPERLASQLKKSEIKRIHDETIRILQLAIEKGGSTIRSYKNSLGEDGSMQDCLQVYGKTDQPCARCATPIEKIKVGGRGTHFCPSCQKQ

mutM

Formamidopyrimidine-DNA glycosylase

272 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.459 kDa

MPELPEVETSRLGITPHLQGQTIKAIVVRTDKLRWPIPQELQKLVGQRVQSIRRRAKYLMIDTPKGSAIIHLGMSGSLRVLDEEVPSAKHDHVDLVLENGKVLRYNDPRKFGAWLYSEVGVAHQVLSKLGPEPLTNEFNSEYFAEKAKNKKTVVKQFIMNNAVVVGVGNIYASESLFMAQIHPKTSVGSLKASQITLLVAEIKKVLETAIKQGGTTLKDFNQVDGKPGYFAQELHVYGRAKKKCLLCSSIIQEEKIGQRNTFWCGHCQPFNK

mutM

Formamidopyrimidine-DNA glycosylase

272 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.215 kDa

MPELPEVETVRRELEKRIVGQKIVSIEATYPRMVLTGFEQLKKELTGKTIHGISRRGKYLIFEIGEKDRLISHLRMEGKYRLASLNVPMEKHDHLALKFTDEQLIYADVRKFGTWELISTDQVLPYFLKKNIGPEPTYETFDEQIFREKLQKSTKKIKPFLLEQTLVAGLGNIYVDEVLWLAKIHPEKVANQLTESSIHLLHDSIIEILQKAIKLGGSSIRTYSALGSTGKMQDELRVYGKTGEKCVRCGNEIQKIKVAGRGTHFCPFCQQK

mutM

Formamidopyrimidine-DNA glycosylase

272 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

29.965 kDa

MPELPEVETVRAGLTPHLTGRQIKAVTVREPRLRWPVDPDLSAKLAGLEVRTVERRAKYLLIGFGHEQWLIVHLGMSGSVRVLPDDTPPQKHDHLDFILDDGHLVRYHDPRRFGAVLWHLGPPDSHPLLSRLGPEPLSDGFDATGLLHALAGRRQALKVALMDNAVVVGVGNIYANESLFEAGLDPRRPALSLTADEAGQLVQSVRHTLARAIAAGGSTLRDFRDAIGKPGYFQQDYAVYGRQGQSCPRCGGLVERCRLGQRSTFFCPACQR

mutM

Formamidopyrimidine-DNA glycosylase

272 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.

30.473 kDa

MPELPEVETTLRGIEPKLVGRSLARVDIRQPKLRWLITPELSSEMVGEEITHLSRRGKYIGIHTSKGTLIVHLGMSGSLYFVPAETPPLFHDHVDFCFADDDVWLRYTDPRRFGAILWTTEDWHEHELIKHLGPEPLSDMFNADMLYVRAKGRKVPIKTFIMDSKVVVGVGNIYANEALFKAGIRPDRLAGNISKARLARLVECIKVVLAAAIKQGGTTLKDFVGGDGKPGYFKQELAVYGRANKACVICSKPLKEIRQAQRSTVFCINCQS

mutM

Formamidopyrimidine-DNA glycosylase

272 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).

Belongs to the FPG family.

31.215 kDa

MPELPEVETVRRELEKRIVGQKIVSIEATYPRMVLTGFEQLKKELTGKTIHGISRRGKYLIFEIGEKDRLISHLRMEGKYRLASLNVPMEKHDHLALKFTDEQLIYADVRKFGTWELISTDQVLPYFLKKNIGPEPTYETFDEQIFREKLQKSTKKIKPFLLEQTLVAGLGNIYVDEVLWLAKIHPEKVANQLTESSIHLLHDSIIEILQKAIKLGGSSIRTYSALGSTGKMQDELRVYGKTGEKCVRCGNEIQKIKVAGRGTHFCPFCQQK

mutM

Formamidopyrimidine-DNA glycosylase

272 amino acids

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Belongs to the FPG family.