Research & recognition

Cell-free systems used in real biology.

Selected publications that use Liberum technologies, use proteins produced by Liberum, or include Liberum researchers, together with independent coverage of the company and its technology.

Expression is only useful when the protein can answer a biological question.

We develop our systems with experimental relevance in mind, from nanobody diagnostics and distributed biomanufacturing to functional signalling studies.

Selected work

Published with, using or enabled by Liberum technology.

Nature · 2026

GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling

A study of glycoRNA and heparan sulfate biology published in Nature.

Liberum use: the Nature methods explicitly identify cell-free E. coli protein production by Liberum Biotech for the VEGF-A165-HS wild-type and R/K proteoforms used in functional signalling experiments.

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Science Advances · 2026

International multisite implementation of distributed cell-free protein biomanufacturing to advance health and research equity

A ten-site demonstration of distributed cell-free biomanufacturing for research, diagnostics, vaccines and other bioproducts.

Liberum connection: the study used Liberum Juice alongside other cell-free systems, and includes Liberum researchers among the authors.

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ACS Synthetic Biology · 2025

A Rapid and Modular Nanobody Assay for Plug-and-Play Antigen Detection

RAMONA, a modular nanobody-based antigen detection platform designed for rapid adaptation and point-of-need use.

Liberum use: nanobody constructs were expressed from linear DNA in Liberum Juice cell-free lysate using a Liberum cell-free optimized backbone.

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medRxiv · 2025 · Preprint

Automated Cell-free Protein Synthesis for Distributed Biomanufacturing

MANGO, an automated benchtop system for cell-free protein synthesis and purification at the point of use.

Liberum connection: Liberum researchers are coauthors on the work, which demonstrates automated production of nanobodies, cloning enzymes and diagnostic enzymes.

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Independent coverage

Liberum in the press.

Selected independent coverage of Liberum and the technology we are building.

CEPI · 2024

Transatlantic scientists to transition traditional vaccine development onto rapid-response platform for faster outbreak control

CEPI highlighted a £2.16 million proof-of-concept program led by CPI to develop the MANGO platform for automated, cell-free production of virus-like particle vaccines.

Liberum connection: CEPI names Liberum Biotech as a consortium partner working with CPI, Imperial College London, University of Leeds, University of Toronto, University of Waterloo and FioCruz on the rapid-response vaccine manufacturing platform.

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Nature · 2024

Cell-free protein synthesis moves toward on-demand biomanufacturing

Nature highlighted emerging approaches to producing proteins outside living cells and referenced Liberum among companies developing cell-free protein synthesis technology.

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IndieBio · 2020

The Future of Drug Manufacturing: Just What The Doctor Ordered

IndieBio featured Liberum's cell-free protein printing technology in a discussion of on-demand biologics manufacturing, describing genetic material being added directly to enzymatic systems to produce proteins in hours.

The article positions cell-free protein printing as part of a broader shift toward flexible, localized and on-demand drug manufacturing.

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BetaKit · 2023

Liberum closes its seed round

BetaKit covered Liberum's seed financing and its effort to compress recombinant protein production from conventional multi-week workflows toward much faster cell-free production.

The article described Liberum's ambition as broader than a single cell-free product, positioning the company around protein synthesis infrastructure.

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TechCrunch · 2020

IndieBio Demo Day: Liberum's protein printer

TechCrunch profiled Liberum as part of IndieBio's Demo Day cohort, highlighting the company's approach to recombinant protein production.

TechCrunch described Liberum's early vision as a protein printer capable of reducing custom recombinant protein production from weeks to hours.

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