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tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Tupiella akineta
Length
600 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
70.685 kDa
Sequence
MTNKLDCLKLINFIEKSNLFTTNKIRDKKLLIAFSGGQDSSCLLTIFYILSKKWGFKLGAVYCNHCWTDSPQSSLSAFDTLQMFDIPFYFVESPNSEPMKPEQKARDWRYSSFYTISKWEDYDFVLTGHSLSDCVETVLFNLFRGSGLKGICSLKEDQKFSNLKTNDFFFQKTVCFLDPFFYFSDKKGNPFFRKYRLFQSMSFLSIFPKFDFFAFGENCAIDKSNFPLKNKSKGKNLQFLTSFDIKNWFGIKKICRFCFLDKIGQTGIKKKRGTNRVPILIFSRRVNKTTSPLALNFQTKNKRVDRKSFLFRFSLAFALPLAFALRAKGEKVRKNALLNQIKPVSFFFKTKKDKTETNLFHRYLQTIKKLQNRDKISSFITIFRPFILTLGNVKIKGKKIKNKNLPFQIKKLIRKKEKEKGILWNSLSKLDNKDKLISNQIQKKGFKLIPKFILTKDKKSFSNFPPFIFDQLEKTFRKEKVDTKPRNSSPQFEVLFNKLSQPSSDKKNVDFIVFRPLIKITRETLFLFSNNLKIPIYYDKSNKDLNITRNYIRKVLVPLLKKINPRVEENIYKFSKIIEFYYQVFGDLKCPSDRFDIFNP
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Length
582 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
62.706 kDa
Sequence
MSLFHLLRRSVTVAVMSESAPNHTSARRLTQPLEPFVGRQVLVGVSGGADSVGLLRALLAVGALPAVAHLDHALRPESVDDAAWVSDLCARLGVPCEVTRIDVGAVAARRNWNLEAARRLRYDVLSRAAKHSGAEVILTAHTRRDQAETVLMELLRGEGRIRGIPPQRGRVRRPWLNVGRAEIETYLRGLGQDWREDASNADPRFTRAWLRREVMPVLLTRFPAAETALAQVAELGAEDDAALQALAARLTPHTPLDRQPPAVLRRWLAAELRSGGLDFTAEQLRDLAGALNAGQTRHLTLPTGRDVTVTGGHLYTAPCDWPEPDFPLPPDWTRRTRQAGDRIRLAGGTRKLSDVLTDAHLPRAERDRVPLLTDEHGAVQWVGVQPPLWAVGARESLGLPADPLHAAMGEALALAQQAAERQEVPVGAVVLNADGEIVGRGRNTSREDGDMTCHAELAALREAAAGLGTPYLSDCTLVVTLEPCPMCLGAALEARIGHIVYGAANPKAGALGGVSDLLADHWGWRPTVQGGVRAGEAARLLREVFGEVRRRSADTPQTPNAETPAPRSSRSTSASGKPTMLE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923)
Length
533 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
57.183 kDa
Sequence
MSTLLAPLHPYAGRVVVVGVSGGADSVALLRALVQAEARPVVAHLDHALRPNSAEDAQWVHDLAEQLGAAHTSTRVDVAAVAARRGWNVEDAARRVRYEVLSRAARQHGAHTVMTAHTRRDQAETVLMGLLRGEAVLTGIPAVRGRVRRPWLDVPRSEIEAYLKALGQEWREDPTNADVTYTRAWLRTEVMPVLAARFPGVEAALGRVAKLAQQDDEALRDLAAALTPHAPRDRVPLAVLRRRVTQELKSAGLQFHVGQVDQLAEAQRTGETRHVTLLGGRGVTVTGGALHLAARAWPLPSFSWPEDWTLRTRQPGDRITLPGGTRKVSDVLTDLKIPRDQRDDVPLLVSAQGVKWIGVEPNIWAKGARAVVGQPADLLDTAMGEALGLAREAALAQEVPVGAVVLGPGGRIIGSGRNTSRADSDMTRHAELAALRAATAELGTAYLTGCTLVVTLEPCPMCLGAALEARVERIVYGASNPKAGALGGVSDLLSSHWGHVPAVTGGVRAQDAARVLRDSFQELRQRRLKSPDV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia peacockii (strain Rustic)
Length
533 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
61.586 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKMSIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIHIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTSVGEEALLRGPVKLTVSSRGLTTVKTIKSTNNFSIFNWIPWSSHGMTEVKLIHATMPREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKRIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQETPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Blochmannia floridanus
Length
531 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
62.978 kDa
Sequence
MNSTNFFSHDLYLYHQVIRCIVKYRNLLLAYSGGMDSTVLLDILTKLKKYFDFQVKGTSKILPFFLRAVYVHHGLNNKADYWADHCLQQCKMRNVPFHIIYINHSDLSKIKCNIEAMARDFRYKALFNALKPEEVLLTAHHMNDQVETVLLALKRGSGPAGLSGMTQDILYQHNEYQHRLLRPLLKCSHIQLQEYAYRKKLTWVEDDTNTDVRFDRNFLRVQVIPLFQKRWPAFNKVVSRTAQLCREQENLLHELLSESLDQLIDIDNALFFYPLIKYSDVRRRVVLRYWLSRFFINMPSYKLLDCIWKEVALSKVDSQSILHVGKKYICRRFRKKLYILPDNMKSSLDIFLLPWKNFNNTILLPNELGLLTSQSLTVNLFLFYKNLIPYTHLNMLSDIFLPRYHNNVGDEKILSVCFIRPPMNNEKVSIQFGYIQGLLHLANRDRGRKLKKIWQEYNVPPWLRNHIPLLFYNDTLISAIGIFITRNGSCIVNMNNLICNNKKSIILQKITWVQSDFYYRIFKNFVYNTLR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Psychrobacter sp. (strain PRwf-1)
Length
525 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
59.124 kDa
Sequence
MTTPVCISQAFMDSFHAHHAQLLGKRVWLACSGGRDSLGLALLCRTLFDQGRLPFLPQLIHVNHGMQAANDEWAQQVAQWAQQHDMACQIIGLNLTHKSEQAARDGRYQAMMQLMNQDDVLILGHHQDDQVETLLMRLFNGAGVTGLGAMREWTSKQAHTAQSPPDVNKPRQRIFLWRPWLEISRDQITEYAQRHNLKYIDDPTNVAQSPSKLALQTLNDRAWLRSVLLPHITERYPQASEAMARTAQLMQQASDSIDEQVTQDLAQVALAATEQQSVIALDKLAGLSAPRQAALIHHWLAPYPNQLPPSKRLVDEVLALSFRQDSNHQTCLYFDAGSEQYQVRRYQNKLYRLQHAYAQWLQMMPHQIHLPLAHNAEELSLNLADTDVLSLKQSGLEFDWQLTGVRGLMAHLARLLNSADAKVTPCQLIFEPLPRTIKLALAGRSGRKSGKKLLQALDQPSFMRGSVVLCRLDMMGSDGILQDSSTAVPLFIICIDRIWVLQSQFTALINQLLATEVLSTQILEC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Blochmannia pennsylvanicus (strain BPEN)
Length
510 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
60.034 kDa
Sequence
MITTNTSSENWDLYRKVTHCLVGHTRLVLSYSGGLDSTVLLDILTRLKNNSDHFTSSPFMLRAIYVHHGISNYSDEWASHCFNQCKIRGIPFSVIHINCYNAENKQRNIEALARNLRYKKLYNRLNSKEILLTAHHMNDQVESLFLALKRGSGPSGLSGMSKNALYANKYRLLRPLLDCSREQLEMYAYKKKLVWIEDDTNTDTRFDRNFLRIKILPSIYQRWPCFNQVVARTAQLCRDQENLLNELLSESFQKLIDESDGSLLFIPLFQYSIPKRQALLRRWLLHFSMKMPSYQLINRIWKEVVLSRKDATPILQLDKYLCRRFREKLYILPVNMRCSLNRIELSWNIIHNVFILPYNLGKLIYQPLSINEHVPKNPFDLHLNINSSLNTSHDVFEKYKKVLTHCFVRSPKSDEKISIIFGNIDGLLYILGRNHGRHLKKIWQELGVPPWLRSRIPLLFYNKTLITAIGVFITHNGKIISKENTLWKISWLQDIISYKIFKNSVRYHLE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length
507 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
56.281 kDa
Sequence
MDVPAFRERLLRLAPKDPLVLAVSGGGDSVALALLVKEAGRQAVVAHLDHGLRPESPLDQAFVRALAERLGFPFFTERVEVARIAQARGENLEAVAREVRYAFLHRVAREVGARAILTAHTLDDQAETVLLQLLQGTARATGIREREGIVVRPLLAHTREELRAYLRARGEAWREDPTNQDPALDRNFLRLFVFPLLEERFPAAKRALARFAEARAEEEGVLERQAEARLLPDPRFFVPAFRAAPLLEAPLAVRRRALRRLLEKLGLRPEARLVLLLEEALRGRPQTLPGGVLARRKGGTLFLLPPRPRLPLPPGFRRPAPGDYLERPSGRKRLVDFLAEKGVPRELKPLWPVRAEGSRVVEVLGLYPPPPEEAHMAEALAEAASAFREGEVPVGAVLVLPGRVLRAHNRVEGLRDPTAHAEMLLLREAGPEARGGRLYVTLEPCLMCHHALAQAGVEVVYGAENLKEGALTRFGLPTRARGGVRERECAKLLRDFFARLREGCRSG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
507 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
56.308 kDa
Sequence
MDVPAFRERLLRLAPKDPLVLAVSGGGDSVALALLVKEAGRQAVVAHLDHGLRPESPLDQAFVRALAERLGFPFFTERVEVARIAQARGENLEAVAREVRYAFLHRVAREVGARAILTAHTLDDQAETVLLQLLQGTARATGIREREGIVVRPLLAHTREELRAYLRARGEAWREDPTNQDPALDRNFLRLFVFPLLEERFPAAKRALARFAEARAEEEGVLERQAEARLLPDPRFFVPAFRAAPLLEAPLAVRRRALRRLLEKLGLRPEARLVLLLEEALRGRPQTLPGGVLARRKGGTLFLLPPRPRLPLPPGFRRPAPGDYLERPSGRKRLVDFLAEKGVPRELKPLWPVRAEGNRVVEVLGLYPPPPEEAHMAEALAEAASAFREGEVPVGAVLVLPGRVLRAHNRVEGLRDPTAHAEMLLLREAGPEARGGRLYVTLEPCLMCHHALAQAGVEVVYGAENLKEGALTRFGLPTRARGGVRERECAKLLRDFFARLREGCRSG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Chlorella vulgaris
Length
504 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
59.973 kDa
Sequence
MKKDSTIISTCNEFSLSSVKTKRVYKNNHLLCSVSGGQDSIVSFFFLVNFLYLSKNFKLIKSKLSSFSVASKSAEKKRCFDCFFSLKKNKKINALINKEKKLSRLDLVFCQHFWQTQNFFCVEFLFQLTFFFDIPYTFVLSKNILVSENRARGWRKKTFSRLLKIQKLSTIVTGQTKTDTAEKSITNLLRGTSPKSFSLITKANSKTTSSFFCFRLFRPKTFYLTLTGNKRERKVNRRISFSFYRTQKKDSKKLRETRAPFFIEMASFSAFFGNTFQKKKSSNSFLLYKTRLSFSFCFSGETREHSINSLKPLQNRNRYHISKLVKFYKFPLTIDATNFSLNFSRNKIRHLFIPFIRFLFKLKFETLLLNFLYLVNLEHEQIENENLELKRVLNFLRINYLKKNFFSSNRRSFFVIQTGHKNNNVFPTKKKEKRWFYCNEIGISKIRKQCKIHEDPILETSLVIYFTSVLTTSRKYSLLQNLLYNYREIEINFRQISKLENSFW
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bartonella tribocorum (strain CIP 105476 / IBS 506)
Length
495 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
56.499 kDa
Sequence
MCVRLARNLFKTSDFIPCRRVILAVSGGSDSLALMFLVKEYLETLLIPPEIIAVTVDHQLRKESAREAEIVAEICRDHHIKHITVRWEGKKPKTHLAFSARIARYDLLVQEAQKQGASLIMTGHTLNDQVETYQMRCQRLQKRRGALRDEVGAMCDGGAASGFAGALRDKAGARRDEDYVRETRKNIAEKSYGVLYERGLSCIPREALLHRKVRLIRPLLGVQRQTLRNYLRLQGKTWIDDPTNEDRNFERVRVRQSLSSQKLVNIAQKINKAAWQRRQQAQNIADLILALDITVQYGRCFIVKPAPFLQKHSCFPFVVGLFAVLMGGGFYLLSNQKLSMLVQKLCLNSPEKRRFTCAGCVIEYNKEGIALWRERRNMKEALVEPDETLLWDGRYRITNHGSEAIKVGVANLEQLKSLLQNSNSNLEKPHFPSLQSLLMLSNDKGCDIPELISQAIIHKNVIIKRIMAPFDWLSSREDAALVNVVEPFFNLEVKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Staurastrum punctulatum
Length
493 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
58.834 kDa
Sequence
MQNNKDNYLKFTKMDKKSIRAPYDQNDLSKKIQRIKKREDIFLLYKINNIITEHTLLQPKQRILIAVSGGQDSICLLRILFDLQRKWSWKLGIIHCDHRWNSRSKIQAEHVACLAINLQINYHEGIAIESVQKESIARLWRYNVIQSVAISNNYTAIITGHNASDRIETLLYNLMRGSGLHGLQSIKWKRNLCFSHFTRSVLSKIKFSFLVKKLKFIKTFMDHEDFQGNHFFFLKKRKQLHLIRPFLETTRTEIRNILTIWNFPSWPDVSNKELRIRRNRIRHRVIPYIRIHYNPNIDQTLVRWAEIVQSETFYLEQLTNYILFKIEIKKKISSISLKIPLEQLRKQKEPSEEKLNFYQSAIPVDLLRSLPVAIQRRVLKQYIYINTNRILGFQYIEQIRLSCLFSLQDSLRKFLHRHRCRPIYLSEHISTHSMKSSTSDTCIDWKGPKEKKKLVTPWLIFPGGIKFLIRKNYLFIFSPKNSSLTIKRPRIEQ
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)
Length
493 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.899 kDa
Sequence
MCVRLAGNLFKTSDFIQCQKLILAVSGGSDSLALLFLVKDHLKTLSVPPEIIVVTVDHQLRQESAREASIVAEICRAHHIQHRIVRWEGKKPKTHIASSARVARYDLLFQEAQKQGATLIMTGHTLNDQVETYQMRYQRLQKSADVLQQEAFAEMGGGVHADVLQQEAFAERCERMGVGGHGGDIAEKSDGLIYERGLSCIPREALLRGTVRLIRPLLGVKRETLRTYLRLKEKTWIEDPTNEDCNFERVRVRQSLQPKKFTCIARKVHEAALQRRQQAKNIADLILALDITVEYGRCFIAKPALFLQKHPGFPFVVGLFAVLMGGGFYLLPHKKLSTLVQKLSLHSSEKRRFTYAGSVIEYNRSGIAFWREARNIKEAIVEKGQTFLWDGRYQITNHSHEPIKVGAAGLQQLKSLFKNNNFNLENTHFPSLKSLLMISNDKGYDIPELAYHAAMQHTITIRRIMAPFDWLLSSQDAAFVNVVQPFFDIKVKG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Burkholderia mallei (strain ATCC 23344)
Length
489 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.2 kDa
Sequence
MIPPHEFSAERVVFDALGVALSALPDDTPIAIAYSGGLDSTVLLHAAARIAGAGRCIALHVHHGLSANADAWLAHCAETAQALGARFDAARVDVPRASGQGIEASARDARYRALETMCARYGARTLWLAQHADDQAETVLLQLLRGAGIAGLAAMAPQYRPALADVVRMRPLLHLLRAQLERYAQQHALRWIDDESNTDTRYARNALRVDVLPALAPHFPGFRDALARTAQHAAAAQRLLDDLAAIDLRAVARADVRVLSRDAFVALDDERGANLLRYWMRSLGLPGASAARLAEMVKQLRAARDAHALRVDHAGWRLRLYRDDVQWEAGDGAASEAARADVADDDAADARDDRADASAAARLPACALAWRGHEVWRLPGWRGSFVFSPVAAHEHDAVPEALLSSAALRACARAGGERMRTWQGGPGRTLKNLFQERGVPAWQRDVPLLYVGERLLFVPRIGVNRATHDGADAPGGWRRIEWRPDMLIA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Burkholderia pseudomallei (strain K96243)
Length
489 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.136 kDa
Sequence
MIPPHEFSAERVVFDALGVALSALPDDTPIAIAYSGGLDSTVLLHAAARIAGAGRCIALHVHHGLSANADAWLAHCAETAQALGARFDAARVDVPRASGQGIEASARDARYRALETMCARYGARTLWLAQHADDQAETVLLQLLRGAGIAGLAAMAPQYRPALADVVRMRPLLHLLRAQLERYAQQHALRWIDDESNTDTRYARNALRVDVLPALAPHFPGFRDALARTAQHAAAAQRLLDDLAAIDLRAVARADVRVLSRDALVALDDERGANLLRYWMRSLGLPGASAARLAEMVKQLRAARDAHALRVDHAGWRLRLYRDDVQWEAGDGAASEAARADVADDDAADARDDRADASAAARLPACALAWRGHEVWRLPGWRGSFVFSPVAAHEHDAVPEALLSSAALRACARAGGERMRTRQGGPGRTLKNLFQERGVPAWQRDVPLLYVGERLLFVPRIGVNRATHDGADAPGGWRRIEWRPDMLIA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Length
482 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.556 kDa
Sequence
MPLLDRVREYVVRHGMLEPGDRVIVAVSGGPDSLALTHVLYRLAPAWRLSLHLFHLDHGLRGEASRADAAFVADLARELSLPLTTVTLRPGELEAMRGSLEDNARRRRYAEMARLAAAIGAQRAATGHNRNDQAETVLMRLLRGSGSTGLAGIPPVRREGGLTIIRPLLGASRQEILAYCRAHGLTPRMDATNLQGDFERNRIRLEILPALTERFGDAVVDNLAQTADLLREEDRLLAELTREACARCGWRETGEATGEPVVELDGTLLVQEPLALARRIVRMAVQRVSGSAYGPGLSAVTRALELAGRTEGSHWLDLPQGVRLSVAYGRCRFARSHPQLGPGAEALEQVWPVAVPGETAIPALGVTVAAELVPPSAMPARLPDDEMWLDRDRLPGPLAVRTRRPGDRLWPAGMQGSKKLQDILVDAKVPRDQRDGLPLLVAGDTVVWVPGVIRDRRFRPDAGTRSAVRVTVRRRPEGSGGD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia africae (strain ESF-5)
Length
478 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.621 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFYHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIQIIRPLYNIPKSKLVEYLVRHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTLVREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKLIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRVARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQETPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Length
478 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.546 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIQIIRPLYNIPKSELVEYLVRHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTLVREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKLIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQETPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia rickettsii (strain Iowa)
Length
478 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.503 kDa
Sequence
MLYEKFEYNINNLIGNFSLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIHIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTSVREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKRIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQEAPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia rickettsii (strain Sheila Smith)
Length
478 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.503 kDa
Sequence
MLYEKFEYNINNLIGNFSLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIHIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTSVREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKRIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQEAPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Treponema pallidum (strain Nichols)
Length
477 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.606 kDa
Sequence
MSESRQKLHPLLVHVARSFGHFLVPRKPSCLLVAVSGGADSLALLYAAHELAPDFGVCACAVTVDHSLRAQEGALDARFVRALCARFSPPLPCFVQQISAGAVHACAKIRGRGVQDAARALRYKVFDHVAARCGAQVVLTAHTRDDQYETLLMRLFQGAAASALQGIRAARGRYVRPLLKVSRTCVEDFLQTRGVRWREDASNTCRKYVRNRIRHELIPALDAVLAGWRSGLDKTFAGISAEHSFCVAALTRWREGCSHAWEPVPRALGTRLRMPRSDFLAAEFILRFFLLQEACVRLGVSHRVPRGALERCARFDGVRRIHVSGLQLERAGAYVLFSCIHASDTARETKKQDAGSPPSSEKQGVSAIYVARPGAYPCACGTLLVEVRPAGVFVCCAQDHVGVGPFSFPFYIRTHRTGDTISIRGGHKGIRKMFSEWHVPLSDRTVLPMIEQDGVLRALYGAALGYQNRYAERTPHE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Treponema pallidum subsp. pallidum (strain SS14)
Length
477 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.606 kDa
Sequence
MSESRQKLHPLLVHVARSFGHFLVPRKPSCLLVAVSGGADSLALLYAAHELAPDFGVCACAVTVDHSLRAQEGALDARFVRALCARFSPPLPCFVQQISAGAVHACAKIRGRGVQDAARALRYKVFDHVAARCGAQVVLTAHTRDDQYETLLMRLFQGAAASALQGIRAARGRYVRPLLKVSRTCVEDFLQTRGVRWREDASNTCRKYVRNRIRHELIPALDAVLAGWRSGLDKTFAGISAEHSFCVAALTRWREGCSHAWEPVPRALGTRLRMPRSDFLAAEFILRFFLLQEACVRLGVSHRVPRGALERCARFDGVRRIHVSGLQLERAGAYVLFSCIHASDTARETKKQDAGSPPSSEKQGVSAIYVARPGAYPCACGTLLVEVRPAGVFVCCAQDHVGVGPFSFPFYIRTHRTGDTISIRGGHKGIRKMFSEWHVPLSDRTVLPMIEQDGVLRALYGAALGYQNRYAERTPHE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia massiliae (strain Mtu5)
Length
477 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.321 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIQIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHRSKPAYREEFKGDTERSTAAYTSVGEEALLRGSILSLEAKFGTMSKAAIISQQLKTNKLIENELKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQETPNCFVTHLSLEDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFAPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bartonella quintana (strain Toulouse)
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.032 kDa
Sequence
MCVKLAGNLFKTSDFIQCRKVILAVSGGSDSLALLFLVKDHLKTFSIPTEIIVVTVDHQLRRESACEAESVAEICRAHHIQHVIVRWEGKKPKTHIISSARTVRYNLLFKEAQKQGATLIMTGHTLNDQVETYQMRCQRLQKSADVLQREAFEDMRDGVCSTETRANIAEKSYGLMYERGLSCIPREALLNQTVRLIRPLLGVKRKTLRAYLRLKGKTWIDDPTNENPNFERVRVRQSLHPKKFAGIAQKVHEATLQRRKQAQNVANLILALDVSVEHGRCFIAKPVSFLQQHSGFPFVVGLFAVLMGGGFYLLPTKKLNTLVSKLCLHSLEKRRFTLAGSVIESNRSGLAFWRESRNIKEGAVEPGKTFLWDGRYQITNRGDETIKVGAAGLQQLKSLFKNNNFDLENAHFPSLQSLLMISNDKGYDIPELTNHTTSQQSIIIKRIMAPFDWLLSCEDVPFVNVLEPFFDIKVER
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus anthracis
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.891 kDa
Sequence
MKDTFVEKVDDFVRQHDVLKERSTIVVGVSGGPDSLALLYYLLEKRAAKQFEIVVAHVDHMFRGDESHEDLQFVQDLCKGLGVICETIRINVSQYQKQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVNYCNELKIIPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQVHEKFQKFSMQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPTFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKVIEFFKRTQPSGSLDFPGDLKIVRAYEECSFGFKQEIVSPFLQDLSVPGTITLSNGDKLVTEVSEDIPSDMNETVFVAKYNDISYPIRIRSRENGDRMSIQGMNGTKKIKAIFIEAKVPREKREEWPVVCDASGNIIWLPLLKRSAFAISKETAKKDKYMIIHYKSKESSGRIMK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.969 kDa
Sequence
MKDTFVEKVDDFVKQHDVLKERSTIVVGVSGGPDSVALLYYLLEKRAAKQFEIVVAHVDHMFRGDESHEDLQFVQDLCKELGVICETIRINVSQYQQQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVDYCHKLKIIPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQVHEKFQKFSMQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPAFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKVIEFFKRTQPSGSLDFPGDLKIVRAYEECSFGFKQEIVSPFLQDLSVPGTITLSNGDKLVTEVSEDIPSNMNETVFVAKYNDISYPLRIRSRENGDRMSIQGMNGTKKIKAIFIEAKVPREKREEWPVVCDARGNVIWLPLLKRSAFAISKETAKKDKYMIIHYKSKESSGRIMK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
55.024 kDa
Sequence
MKDTFVEKVDDFVKQHDVLKNDSTIVVGVSGGPDSLALLYYLLEKRAEKQLEIVVAHVDHMFRGDESYEDLQFVQGLCEELGIICETIRINVSQYQQQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVDYCNKLNLMPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQMHEKFQKFSVQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPAFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKLIEFFKRTQPSGSLDFPGDLKIVRSYEECSFRFKQEIVSPFSQDLLVPGTITLLNGDKFVTEVSEDIPSNMNETVFVAKYNDISYPLRIRSRENGDRMSIQGMNGTKKIKAIFIEAKVPKEKREEWPVVCDASGTIIWVPLLKRSAFAISKEMAKKDKYMIIHYKSKESSGRIMK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus cereus (strain ZK / E33L)
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.8 kDa
Sequence
MKDTFVEKVDDFVKQHDVLKEHSTIVVGVSGGPDSLALLYYLLEKRAAKQFEIVVAHVDHMFRGDESHEDLQFVQDLCKGLGVICETIRINVSQYQQQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVDYCNKLKIIPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQVHEKFQKFSMQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPAFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKVIEFFKRTQPSGSLDFPGDLKIVRAYEECSFGFKQEIVSPFLQDLSVPGTITLSNGDKLVTEVSEDIPSDMNETVFVAKYNDISYPLRIRSRENGDRMSIQGMNGTKKIKAIFIEAKVPREKREEWPVVCDASGNVIWLPLLKRSAFAISKETAKKDKYMIIHYKSKESSGRIMK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.861 kDa
Sequence
MKDTFVEKVDDFVRQHDVLKERSTIVVGVSGGPDSLALLYYLLEKRAAKQFEIVVAHVDHMFRGDESHEDLQFVQDLCKGLGVICETIRINVSQYQKQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVNYCNELKIIPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQVHEKFQKFSMQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPAFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKVIEFFKRTQPSGSLDFPGDLKIVRAYEECSFGFKQEIVSPFLQDLSVPGTITLSNGDKLVTEVSEDIPSDMNETVFVAKYNDISYPIRIRSRENGDRMSIQGMNGTKKIKAIFIEAKVPREKREEWPVVCDASGNIIWLPLLKRSAFAISKETAKKDKYMIIHYKSKESSGRIMK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
476 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.986 kDa
Sequence
MKSIEDFMKKYELSFDGVTLIAGVSGGPDSMALLHALHHTVPASATLIAAHVDHMFRGEESERDMRFVQDYCEAEGIQCEAVQIDVLAFAAENNLNKQAAARECRYAFFQELMKRHRAEYLVLGHHGDDQVETMLMKMAKGTVGIGLAGIQPKRRFDSGWLLRPFLKLSKDDLLAYCKENRIPFRTDPSNSEDDYTRNRFRHHVLPFLKKESEDVHKRFQSVSEFLTEDELYLQALTKDKMNTVITSKSSSGVEISIERLLALPMPLQRRGVHLILNYLYENVPSAFSAHHIQVFLDWISQDGPSGSLDFPNGLKVAKSYHTCLFTFQRLQCENVSYHYEISGAGEEELILPGGSSLHVSGPGSTRKLQGNDVFATSPKQVQFPLYVRTRQNGDRVKLKGMNGSKKVKDIFIDEKVPLSKRDSWPIVTDAVGNIIWIPGLKKTIFEELDVTNNDRIVLQYRQHEKCRGLAKNETGY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus subtilis (strain 168)
Length
472 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.464 kDa
Sequence
MKSVKDFLNKHNLTLKGATIIVGVSGGPDSMALLHALHTLCGRSANVIAAHVDHRFRGAESEEDMRFVQAYCKAEQLVCETAQINVTAYAQEKGLNKQAAARDCRYQFFEEIMSKHQADYLALAHHGDDQVETMLMKLAKGTLGTGLAGMQPVRRFGTGRIIRPFLTITKEEILHYCHENGLSYRTDESNAKDDYTRNRFRKTVLPFLKQESPDVHKRFQKVSEALTEDEQFLQSLTKDEMNKVITSQSNTSVEINSSQLLALPMPLQRRGVQLILNYLYENVPSSFSAHHIQQFLDWAENGGPSGVLDFPKGLKVVKSYQTCLFTFEQWQCKNVPFEYQISGAADETAVLPNGYLIEARHYADSPEEHGNAVFITSEKKVRFPLTIRTRKAGDRIKLKGMNGSKKVKDIFIDKKLPLQERDNWPIVTDASGEIIWIPGLKKSIFEDLVIPNSDRIVLQYRQHEKCRGQAKS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Dehalococcoides mccartyi (strain CBDB1)
Length
471 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.987 kDa
Sequence
MLTERVSKYIKKQGLVSAGDEILLAVSGGPDSVCMLYIMHKLSREMGFSLRLAHLNHGLRAEESDRDAAYVTELASALGLPLCQQKVSVKAYQAEHHLSLEEAAREMRYAFLCRTAAEFGSAAVAVGHTLDDNIETVMLHLVRGSGTRGLQGLRPVLNRTIAGAGCLRVIRPLLCLGRAETQVYCREAGLLPRQDITNLSTEPLRNRIRLEVLPLLKTINPAFEETILRTAFIAGEEMALLDEVTSQMKAELVIRQDDVLMIEKIEMQRLHPALKRNLLRQMMEELLGGLKDIEARHIENIVQTMDKPAGRRIDLPYKLVFQVDYEHYLLGWGIDELCPYPPCQGEYRLGVGTETFLDGWVVKTEILPSPIGLDLSESSLVAYLDMDKAGTDLIVRTRAEGDQFQPLGMEDAKSLKEFMIDNKIPRNWRARVPLLISSKEILWLVGYRIGESAKVDENTRRVLRVEFRLLG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Desulfotalea psychrophila (strain LSv54 / DSM 12343)
Length
471 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.213 kDa
Sequence
MLEKTIYYKMITLKVKNIIKEKLPLKSGDKIIVGVSGGADSIALLHILTELNLDLQLIAIYIDHGLRPDEIPQEISFVKGQAGAVGAEFESISVDVLALKNCDKLSTEDAARRLRYQAFAEARERYGAKYIMVAHNADDQVEEFFIRLLRGSGRRGLSGMPYQNGLLLRPLLSLTKADLLLYLQERGIDHCEDSSNREPCYLRNRIRLDLLPRLEEYNPSLRRTILNTSSILESEEDFLEKSARELFNRSTRINREGKLPKTELDCRSFSGGHQALQRRVIELICWQMDAQPSFTHIENICRLATEGTSAKTLQLGSGLRVKKEISQVVFHYPLGRIATRQGEREIRLERRIDGEGIFAIPELNRQLTISTGEGAGEGRLLVDREKINFPLLLRFHRAGEKFHPLGAPGRKKVSRFLTDKKVHGEDKQLYPVLINGDGNIIAIVGLAIAAQFKKTETSKQLISIGWQETTT
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
471 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.162 kDa
Sequence
MKTLSPVDAVLKKVRAFNAEHGMFRPGDRVVVAVSGGADSVALVDILVSLNELRLDLVVAHLNHKLRGAASDEDERFVEQCAQTYALPFVSRGEQVKALAEWERLSLEDAGRRARYAFFDDVAAACGARTVALAHHADDQAETLLMRLVRGAGGLGLSAMQPVGAGGKYVRPLLALGRQEIEAYLDARGLAFRQDQSNTDVAFLRNRIRHELVPYLGRLNPGAASRLARTAELLADDEALLSRLVEEALRRHVMVTEQGGAICSVDTLRREPRGLRRRLYRKAIALAKGDLARISFDHVDAIDRLVLSENPSGRLHLPEEILVTRSYNEVAFARRMADIPSLQELWIDGPGCWPLSGGGELVVEIATGPPPWGELSTTESWFDLELAPFPWLIRGWRPGDRMIPLGMTGEKKVKDIFIDQKVPRELRRSIPLLFRGDSLLWVCGCRRGESARITAGSRAMAVVRIRGRRLK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Shewanella woodyi (strain ATCC 51908 / MS32)
Length
470 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.772 kDa
Sequence
MTEPSFNTSALIEESIKSAKINVGAKLVLAYSGGVDSEVLAQGLSLYAKSHPEFRYLLVHVHHGLSRNADAWVTHCQKQALDYQLPIEVVQVQVKTGPRLSIEAEARRARYKAITSLMDSADVLLTAHHLDDQLETVLLALKRGLGPKGLSAMGALQVFDGDKQLLRPLLNVSREQIEAKAASLSLPHIEDESNTDDKYDRNFLRLQIIPKLKSRWSAIATTASRSAALCAQQQAVIDDEVSARLPNFIELVPYGEGTALNLDLLSHQTPNWQALLLRGYIESSGFAPVSQIQLEQLLSQLLTAKPDANLEVRIADMLVRRFREKAYLSSYRPHKPKSLESIELTLESEVHFVQEINIPLLSNIRVEVLEDDGGERVRLPLIEEKVSVRFSAVGSLRCHPHNRQKGRELKKLWQEYGVPPWERERVPLIFYNEKLVCAVGYWVEHSFQSAEHETGLRFSIAIVSNECESI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Heliobacillus mobilis
Length
470 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.601 kDa
Sequence
MNHLLQRFSQSLCRLGINKPRERIVIALSGGADSVCLLLLFKKVSPQFGIELAAAHYNHGMRGKESDEDAAFVAELTNRLQVPLFLETAPLKWWQQEPGTKMEAARRLRYDFLSRSAEQAGARWIALAHHADDMAETVLFHMLRGSGIKGLSGIPAKRGPFVRPLLPFRRKELEEFLKAEGQHWRHDSSNDSDVYTRNRIRHQIMPALLSFNPKLVETLCRNADLLRADAEFLDRECELVYGQVQQEEGLKVQALVDLPLALRRRVLRRFLEPENPGSEKTDAILEQLQKNFGRSKIVDQVGGKYLINEGGILRSYEELPWLENQDFFYPIAIPKEKNHSVRLEVPEAEGSLEVTLSTKKPVSLMHDEGPPSKPMKTALQLKAEVLQRGPLSIRNRRPGDWLSLAGRAGRKKLKEFFIDKKIPRQLRDRIPLLTSGEEVLWVIGCWTGCHDTIDQPGQDVITFQWYGKTI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)
Length
469 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.18 kDa
Sequence
MKKKVIDFIKENSMIKNGDKVLVALSGGPDSVCLLHILSELRELLHIEVYAAHVNHCLRGESALKDEAYVEELCKNLNIKCFVKRVDINKISEEQNISTEMAGREERYKFFEELKNEYSLDKIAIAHNANDQAETLIMRALRGTGIEGLVGIKPVRDGIFIRPILILRRKEIEEYCEINNLNPRIDETNLEEIYSRNKIRLKAIPFIEENFNPDIVATLNRLAYSCSKDVEFIQEEVEKRFPKLCIKENHSILIKEEAFNEKEALLTRIIKKALFEVSSKHNNFELKHIQDIIALKDKGTGKQINITNGVIALNEYGDIRIKLVDSKKAKENKVLNLENIKDELDKNQKVVIEDDILGNYELIVEDLKKGEKFSKDRFIKSFDYDKISNIDIRFRQNGDKIIPLGMKSSKKLKDIFINNKIPKEERDFIPLVLFNNEIAWIVGSNVSETFKVTNKTKKVIKITFKGKEN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Clostridium perfringens (strain 13 / Type A)
Length
469 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.139 kDa
Sequence
MKKKVIDFIKENSMIKSGDKVLVALSGGPDSVCLLHILSELRELLHIEVYAAHVNHCLRGESALKDEAYVEELCKNLNIKCFVKRVDINKISEEQNISTEMAGREERYKFFEELKNEYSLDKIAIAHNANDQAETLIMRALRGTGIEGLVGIKPVRDGIFIRPILILRRKEIEEYCEINNLNPRIDETNLEEIYSRNKIRLKAIPFIEDNFNPDIVATLNRLAYSCSKDVEFIQEEVEKRFPKLCIKENHSILIKEEAFNEKEALLTRIIKKALFEVSSKHNNFELKHIQDIIALKDKGTGKQINITNGVIALNEYGDIRIKLVDSKKAKENKVLNLENIKDELDKNQKVVIEDDILGNYELIVEDLKKGEKFSKDRFIKSFDYDKISNIDIRFRQNGDKIIPLGMKSSKKLKDIFINNKIPKEERDFIPLVLFNNEIAWIVGSNVSETFKVTNKTKKVIKITFKGKEN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus clausii (strain KSM-K16)
Length
469 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.274 kDa
Sequence
MEARVEQFIENNRLFGMETNVLVAVSGGPDSMALLAIMANLREKWKLNLFGVHVNHRLRGEESNKDAELVQSFSARLGVPCNVKDVDVAAFKAEHHVGTQQAARALRYQVFQGEMERVHATVLLTAHHGDDEVETAFMKLTRGTTPLTKLGIAATRPFANGVLARPLLEETKRSIVAYCHEKAIPYRIDQSNFSDAYTRNRFRMNMAPYLVEENPHIHKHIGRFDRWQEEDNHYLMEQAKAHLDQILTKKSEKSIELEIQALCLAPFPLQRRMIHLILNYLHLNVYGVNDMRVFPDAIEQIQAFLQTSAPSAQLDLPGRVQVKRSYGTCLFTTAPFIETKAYCHLLSIPGKVDTPLGVIRADTREELLELEHTDAVSFQVSQVAFPLYIRNRKPGDKLSPSGMSGSKKVNRLFIDRKVDRAKRDAWPLLVDANDSILWVPSLQTSRILTRSANVQGELLHVTFSQHKWP
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505)
Length
468 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.964 kDa
Sequence
MPADGIPEGIPAEDLLRASIEVALAAVREPLVLAVSGGSDSMALLFAMERWAPDRIAAVATFDHGTGSYATDAASLVAAHGRRLGLTVIRERARRPGVNEAAWRDARWSFLQRVARGFHARVATAHTRDDQAETVVMRLLRGSGARGLAALAAPSPVVRPWLGVSREELTRWLASEGLPFLEDPMNASRYFLRARVRHELLPACEAASPGFRDAMLLIGERAARWRREVEQYLDQAGLVVEHAGRSASLPVEVLEQTTPEGQAVLWAALSARAGVTLDAHGTRAAVRFTSSRRRGAYITVAGGAAIMRTRRAAEQVASDVGADRGIRAPAGVGERFVVRSRAAASEAVEWSGESTTLPRRLGQWRFRRLAAAPAAFDAWHMGLPAGTSVVVRPWREGDRIRSAGAAAGRRVTRYFTESRIPVPDRSQWPVVLVDDEVAWVPGVCRGLAAPSRSGRSELIWYRCEREFD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Length
467 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.355 kDa
Sequence
MTMSFQRFGMIEKVLRTIEKYNMIEKDDKIVMGISGGPDSLCMLDVLFNLKGKFNLKLYVVHVNHMIRGEDAKKDAEFVEKLCKDLDLPFFLFEENIPYLAKKMGLSEEQAGRYVRYKAFEETLKRVGGNKIAVAHNKNDVAETVLLNILRGTGLRGLIGIKPVNGNIIRPLIEIERREIEKYLKDKNLHPRIDHTNYEDLYTRNKIRLKVIPYIEEVFKIDLVENLSRMAAILLEEDDYLEAKCEEVFNQICEINGEEIKVDVDALKSQHTAIKRRLVRRMYFYVKGETDGLEYGHVEDVLNLLDKPTSSKIDLPFEIEALKMYNNLVIRKKKTKEKVKFKEVLKIPGVTTIEGIGKFKAYVVDISQVDDFNKGEYIKFFDYDKIKGEIVVKSREDGDRFSPLGMRGTKKLKEFFIDEKIPREERDYIPLVAIGKEIVWVVGYRMSEKFKVDKNTSKVLVIEYTKE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Clostridium tetani (strain Massachusetts / E88)
Length
467 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.646 kDa
Sequence
MIDIVLNTIHKYNMINKGDKIIVGVSGGPDSMCLLHILYRLRDEYNLNIIAAHINHCLRGKDADNDEKYVENFCKKYDIDFYSTKIDVGKLAKKENISFEVAGRECRYDFFNKLKLKFNCDKIALAHNSNDQCETILMRIMRGTGIEGLAGIKAIRDNIYIRPIIEASRKQIEDYCEEHELEARIDKTNLESIYARNKVRLELIPYIQENFNQDIIAVINRMGNNIDVDREYLDFASDKKFYQFCTSTKYEVVIKKEAFLEHKAITSRIIRRSINRLKGNLYNFERVHVEDILNLQKGSTGKFITLPEKIKALNNYGDIHIFFEEFSDNKGENKEKEQILEIGNNIINSNIKVQIELTNEIHKDIMGKDVYVKYFDFDKINGNIMFRYRKDGDRFTSLGMKGSKKIKDLFIDFKIPKHLRDYVPLICFGNEIAWIVGYRISEKFKVEKNTKNILKIKIEGEKENELV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Length
466 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.481 kDa
Sequence
MKQSILSFIQKHQLLKEGAKIIVGVSGGSDSMALLHFLKNLQEQWEIEVIALTINHQLRGEDSTADQKFVEQWCFHSDIRCIAHQVDVGEYQRQYRVSEELAARRLRYEIYEAEMRKQGADYLALGHHGDDQVETLFMRLTRVATSNAFEGIPVKRSFASGQLIRPFLCVNKQLILNYVKENEVPFREDQTNKDNKYTRNYYRNEIIPLLTKNNERLFITAQRLSETLREDENYLAKEANRMVEEVIIWDENFSKISFSNQAFIERPHALQRRAYHLILNYLYDTLPKDLSYIHEEKFFALIERQEGNTYIDFPLSLRVENSYGKIQLYFPNRHPRHSVFHLPLQVPDQVELPDGARITSEWIDATLDKNSRNNIIIPIDSVALPLHIRTRKPGDRMTWDGLKGTKKLKDIWIDAKIPTNERDTWPIVTDDNNTIIWLVGLKKAFGSNQFCQSGEKIKLSYHKGNI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Anaplasma marginale (strain St. Maries)
Length
466 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.344 kDa
Sequence
MSGVRIPLFPRFIPHGTVKLESAALKKLNSLELSGGYAVAVSGGVDSITLLNLVAALHKTQATSRPVVLTGNHGFRAEADHETRFVQKRAVALGLDCEILRWNRHRTSSKSQETAREIRYSLLHQWCTEHSVKFLLTAHNKSDQAETVLMHLERGSGIDGLSGMHERSVFGDITIYRPLLGFTRQEILEYATQKQLSWVEDPSNQDPKYRRTFFRNLIAESKNPGVVVDRLCRTTSHMHRALACILHYVRSSLDYCLEFSPLGFITVKSQELRSVPEEIASRLLLLSLMAMGGKDHKPRYSAFWPILTKILQGQDFTPRTLHGCKVRKEPDGNFSIVRELARIETKIGVKTIAETIQWDRRFAIKIMCTHNASAAETTSCSAKHAPNPSEETQNLYITPLGNGSLPEHLVHVNRDVACSLPVLAHGDKVLAYPWQNHNIGVSPTISVEEVLVRRGVINLICHQLYR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Shewanella oneidensis (strain MR-1)
Length
464 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.123 kDa
Sequence
MTAQDLSVHIARWLDSLPLQAGSKLVLAYSGGVDSEVLAYGLSEYAKQRPDLRYQLIYVHHGLSPNADNWAKHCQARAAIYGLPVTVERVQLILGPRVSVEAEARKARYQAILPHLNPQDILLTAHHEDDQLETILLALKRGQGPKGLAAMGQIQPLSLADKGSCLQVRPLLDISREMIETFAQTRQLVHIEDESNQDDKYDRNFLRLEIIPRLKARWPSIATTASRSAQLCAEQQAIVETEVSERLPKLLVKAPVTEQTVLKLSELAAQPIEWQGILLRGFIESQEFSLPSYVQLQQMLQQLIHAKEDAKVHIRINDCVLRRFAGMLYLDSGETLSTALHITARDLHQEILTLLTQASAMVEDKIVPFALVTTGPRLRLPKADEVVSLGYGLPGQFRCQPHFRDKGRELKKLWQECAVPPWLRAEVGFLFYNDKLVMAFGLWVEKAFCAQGDEIGLSYLIANP
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Geobacillus kaustophilus (strain HTA426)
Length
464 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.105 kDa
Sequence
MIDKVRAFIHRHQLLSEGAAVIVGVSGGPDSLALLHVFLSLRDEWKLQVIAAHVDHMFRGRESEEEMEFVKRFCVERRILCETAQIDVPAFQRSAGLGAQEAARICRYRFFAELMEKHQAGYVAVGHHGDDQVETILMRLVRGSTSKGYAGIPVKRPFHGGYLIRPFLAVSRAEIEAYCRQMGLSPRCDPSNEKDDYTRNRFRHHIVPLLRQENPRLHERFQQYSEMMAEDEQFLEELAADALNKVMEKQHRDAALSIGPFLELPRPLQRRVLQLLLLRLYGGVPPTLTSVHIGHILMLCERGRPSGMIDLPKGLKVIRSYDRCLFTFDAESGEKGYWFELPVPALLPLPNGYAIISEFGEHYPRKQAGNDWFVVDPASVSLPLRVRTRRRGDRMVLKGTGGTKKLKEIFIEAKIPRMERDRWPIVEDADGRILWVPGLKKSAFEAQNRGQARYILLQYQAMNS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Peptoclostridium difficile (strain 630)
Length
462 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.595 kDa
Sequence
MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKKDFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEEGARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNCIIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIESIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNSIKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEEIEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSRRQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDENTKEVLKINFNKL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
462 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
54.12 kDa
Sequence
MFWQFYKRGKEQGFWQPHQTIVVAVSGGVDSMALLTLMEQVAEKEQLQLVVAHVNHQLREASAQEAQYLATYCQQRELTYYETRWEDPEKQRNLEAKARTFRYEFFKEVMEIEGAAVLMTAHHLDDQAETILMKLIRGTNFSHSAGIKERRPFATGELIRPLLIYPKEELYQFAQRQAFVYFEDETNQTNEYLRNRLRNQVLPLLKQENPQFLDQIASFSNEQRFAQEFIQEQIEPQLSEAVEPTKQGWRIPLKRLLKETPAYQHFFLTAFFQKTLVPLGVSLNQRQMTQILKVLNDERQPQGSVMLEQQWQLAKSYDWLCLEQKQAALREEVTHLLVPGAGIYLSETEWLGLIATDKPFPLPEEINQWTGQLLAIPLTTATPLTVRHRQSGDRITLKPGFTKKLSRVFIDQKVPNEARESAWVITDEQEEIIWVPKFANSYLSIPLETDKIHYRLLFKTKE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
462 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.668 kDa
Sequence
MKQDVLNFIEEHRLFASGGLVIVAVSGGPDSMALLHFLFSHREQLGITVMAAHGNHQLRQEADEEETFVHQFCLSHGILFTSARLPVKERMEMSGEGVQVTARELRYKWLEAEAKKHGAAFIATGHHGDDQIETILMKQVRGTFPLSRGGIPVRREVGDVLIVRPFLGITKGQIEHYCKEVNIEPKRDPSNNASSYTRNRFRHTIIPFIRGENPNAHLHFRRISEWKEEDECFLLDLAENALADVLLHKDEHLVTIDRDAFLNVGLPLQRRMIHLILKYLYTNDSPANGFIHIERIETLIRNDVTGTKLHLPMGITVERVYGQIRWVRASGEKQPVPVYPVVIEGEGQVSTPFGRFCVVQLVSGPRSMSPFTFTCSASDFPLTVRSRRTGDRIVLSVGTKKVSRLFIDKKVEREVRDRWPLVFNQSSEIVSVPGLYNHPSQKHKQDFQVTFTPKDVRLEDYV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Ralstonia solanacearum (strain GMI1000)
Length
462 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.155 kDa
Sequence
MLLVDKVAQRVVACAAFVVSGGVPTVAVALSGGRDSAALLHAVAAWRDAAGVPVRLVALHIHHGLQADADAWEAACARMAAAVGAAFRVRRVRVSTDAGRGIEEAAREARYAALDALCAETGATLLLTAHHLDDQAETVLLQLLRGAGLDGLSAMPMARERRVTLLRPWLDVPRGDIEAYARAHALAWVEDPSNGDARYARNALRPLLAGMAGHFPAYRASLARSAAHLAEAAALIEEVAQTDLARIAPAGTLAVAGLAALSGPRQRAALRAWLAGAGLRAVSSRRLEDLRAQLLGARADGAPCVRLPGAQVRRYRGQAWIEAAGQPGAGPADCPIAVSRFDPARAEVQRVDVAAWGGALLFSPAQAEGIDARILQAPLSLAARRGGERIVLRPGGPSRALKQAYQEAGIPAWARARLPLLYAGERLVFAAGLGPDRSAVAMGSGWHVAWLPAVGQDGLDAG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Length
461 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.671 kDa
Sequence
MINDVINTIEKNSMIKQNDRIVVAVSGGPDSICLLHILFKLKDKFNTSICAAHVNHCIRGEAADKDEEYVKKFCEKLDIQFYVKRVDVNKIAHEKKISSEMAGREIRYAFFEEVKERFKANKIAIAHNANDQAETIMMRIIRGTGTEGIKGIRPVRDGYYIRPLIEIRRSSIEKYCEDEKLMPRIDATNLERDYNRNKIRLDLIPYIVKNFNEDIVGALNRLGELVTIDNDYLEKLAKSKYKLYCNECEKQVIISKEAFSNDTAILSRIIRRAVFYLVNSKYNLEKKHIDSIIGCQKNTTGKQINLPNNMRAYNNYGDICLRIKEDESCIGKKEYNLHMDKLNSVHEENLIIGIRLIHNSKDIRLEGNKNVKYFDADKAGKYITLRYRSEGDKFMPFGMKNNKKLKDIFINLKIPREERNKIPLICFGGEIAWITGFKISEKFKIDNNTKKILEIKIEREE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Length
460 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.303 kDa
Sequence
MCKIYLMAKSFLKDVLLGFSSLCDRTAAPLRLLLAVSGGADSMAMLSAFLELKSDINAEIFVLTVNHNIRPEKETLGDAQFVLDFCNDKCPCILAEIPKNTVFDEAKNRKTGIEDAARFLRYNEFEKAADSLNADYILTAHNKNDNYETVLMRLFQGSEPEALMGISPRRGRFIRPMLNISRSEIEEYLKEKNIPWREDATNLEASYLRNKVRHNLLPVLSICFDGWQSGLDKSLAKIKAQNDFVIASYKTKKEEWVLDKKEDCCRCKFLFFLSLDEALKLKFLQEGLILLKGKRRIPYSVFDDLMKLSDTKKIIFSGGFCIKKEGDEVLLFKAVTEEKTSEVFYSIWIDKPCSFDTPAGNFKALENDDGFFIVHESDKTCGIGPFKPPFCVRSRLFGDEIETSSGSKKSVKKIINEWNIDYENRNILPIIEEGGVVKGIYGAVFGKKNWYVVGDLGVKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Yersinia pestis
Length
460 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.675 kDa
Sequence
MNLVTSKPNVLLNPLFAQLGENRHVLVGFSGGLDSTVLLHLLVCLRQQLIPELNIRAIHIHHGLNPQADSWVKHCMQQCDQWKIELKVVRVNIDPRQNGIEAAARTARYQAFSANLAAKEVLLTAQHLDDQCETFLLALKRGSGPAGLSAMAAKMPFAHSQLLRPLLAFSREILENYAQAQQLQWIEDDSNQDDRFDRNFLRLNVLPILNQRWPHFAQATARSAGLCAEQEQLLDELLAENLQQLQGPDRSLSIDGLLQASMAKRAAILRRWLASLGAPMPSQSQLQRLWLEVAMARQDAEPQLMIGTRQVRRFRQHLYLLMPLAEITTNYLPWATVKAAPNSSIIPLLPEPLWLPADLGVLRFVSAGGQAVRPAAVGEEISVRFGLQGDIKIVGRHHSRQSKKVWQELGIPPWQRERIPLLYFGEQLIAAAGVFVTQAGQANENEPCWHLDWDKPLRLG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
460 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.647 kDa
Sequence
MNLVTSKPNVLLNPLFAQLGENRHVLVGFSGGLDSTVLLHLLVCLRQQLIPELNIRAIHIHHGLNPQADSWVKHCMQQCDQWKIELKVVRVNIDPRQNGIEAAARTARYQAFSANLAAKEVLLTAQHLDDQCETFLLALKRGSGPAGLSAMAAKMPFAHSQLLRPLLAFSREILENYAQAQQLQWIEDDSNQDDRFDRNFLRLNVLPILNQRWPHFAQATARSAGLCAEQEQLLDELLAENLQQLQGPDRSLSIDGLLQASMAKRAAILRRWLASLGAPMPSQSQLQRLWLEVAMARQDAEPQLMIGTRQVRRFRQHLYLLMPLAEITTNYLPWATVKAAPNSSIIPLLPEPLWLPADLGVLRFVSAGGQAVRPAAVGEEISVRFGLQGDIKIVGRHHSRQSKKVWQELGIPPWQRERIPLLYFGEQLIAAAGVFVTQAGQANENEPCWHLDWDKPLKLG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Length
459 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.23 kDa
Sequence
MRSALPTFDEIWQRKFRHRLLIQAQQFPADTVFLIGCSGGMDSMLLLHLMSELFPHKVRAIYIDHQLQSSSRAWGVFVQNFAQQSHIPFTIQPVIVDTGNLENQAREARYAAFESHLKSNEVLVLAHHQQDQTETVLLRLLSGSGVKGLGAMKEIEQKKNICCWRPMLSVSRQQIEHWVEHLKIPYIQDLTNFDTTYDRAWCRETVWPVLQKRFPKMQEAISRTSILMQDADEILHEVLQQDLNQCGDLNHLDLSRLQQLSLARQRQLLSFWMKGKAIYRPAFEMVERVQQEVICAKADAKAALHWNHHYYVRYQNILYRVEKNKYLQKDLVSNVVSTIELQMDASLQLASGVFQIQPMQMGLSPQLFEQPLQLLPRQGGEKIHLYGRVGHWPLKKAIQEAQILPWLRHTIQILALDNVMLGVFTPKGFWLAQSSYCEAGGWQPNLISDVNYLRVEQNS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Length
458 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.933 kDa
Sequence
MADSKSISPTDITDCFFHNLRAQVRPGDRLTVALSGGVDSVVLLHLLTTFSESMQLEVSAVHVEHGISTYSGEWSAFCQSLCDSLAIPLSIHRLKIRRRPQESLEAIAREARYQIFKHIQADYVMLAQHQDDQVETLILQLLRGAGVKGLSAMPTVRLLEPGKTIRLFRPLLNIPRSEILNYARLHGLSWVTDESNLDTSYDRNFLRHQILPLLEQRSPAYRKTLFRSTQHLGEAAHLLDELAEIDAENTLVTNRLSLQGLRKLEPARARNLLRYLLAQRLIRLPNSTKLEEILRQLNNIQPDNHFRFIVDTLEIRCHRGLIEFLPADSLPEPIAPVVWQGEQHLVIESLQGVLKFTRQNNMGIDPARLSGQIVTIRSRSGGERFQPDCKRPRRSLKKILQEAALAPWVRNTLPLLFCEDQLVWVAGIGIDCNFQISEGSTGLVVAWHPSQINQVSTH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Protochlamydia amoebophila (strain UWE25)
Length
458 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.186 kDa
Sequence
MSCICLKNEKLNVINQVKRFIKKYCKSTQPLLLALSGGADSLSLFYCLLACRLEGILSFHVAHVDHGWREESAKEATILKNLAEQHQVPYHQLKIDLSQLAGNLEDACRKQRQKFFKEICLQNNLQAVCLGHQENDQVETVLKRILEGSHWSHFDGLKERMWHDQVQFLRPLLGIQKDEILAFLKGNQLKAFEDGTNCDERFMRARMRRTIIPDLNRSFGKKIDNSLVYIASEMSELKNFFLGRVSPLLGQIVKGPFGVYLNLANHPSIDLVEIKYLLRLISEQELFFLSRQILQRASEAIEKLEPQLSFEMGTKKIVIDRGHFFILSKKTACKNPNLQISGSSLQYYGKWMIKTNESFYHQNLQASTWLDGWRGYLKTYLPLDKYVLGQASKHAKLLRHHSTINKWWSSHHVPPFLRSFFPVIWQHNEIAHEFLTGLERQNLQEGEKCLQIELSYLT
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)
Length
457 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.435 kDa
Sequence
MKKMASFSLTTLLKNLGKHHKFLVAFSGGLDSTVLLHGLLSLRDQNHLKLNIRAIHTHEKLIHRPENWSKDADQRLTHCQSQCEQWKVPLEVVKMEVEPRGKGIEAAARTVRYQIFSNALKKDEVLLTGHHQNDQCETVLLALKRGSGPAGLSGMPLAMPLGQSQLLRPQLSFSRHSLQLYALEKGILWMEDEDNQNDRFDRNFLRRHILPLLTARWPHFLESTSRSAALCAEQETLLDELLSEQLCQLQSQEGTLSIQGLAACSEVKRNALLRRWLDSKKVPMPSRDQLARLWKEVALAKSDAQPYLQCGEYQIRRFREHLYLFKSSKKSQPCPALFSIKWPFTPESENKLVLPDHLGELKCTPYRSEGQVIRAPQKNEVISIRFGLTGNIKILGRDRSRHSKKLWQELGIPPWERKRIPLLYFNETLIAAAEVFVTQKGEAKQGEPHCYLEWVKS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)
Length
456 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.357 kDa
Sequence
MGLSPSNISKLFEPFGFEQAKAVIAAVSGGSDSLGLLFLVRDYMAMLQNPPRLIAVTVDHQLRAESKAEAENVGLLCRQYGIEHRILVWDEAKPTSGLAAAARTARYRLLVQAARDVGGAFIVTGHTQDDQIETFLMRKERSAHAEARGLAAMSLRSLLDGLGLEGSVELDRPLLSVSRQTLRDELRGRGINWVDDPSNANTEYERPRIRHGIAAEADRQTVLDQIAEAGAARERDNAALIAALGNPASLRADANGALLVDPQLYAALPGNARRLFSGLLAAIAGGRRFLPGDSERSRIERVLSGDDDTHRLTVFGALIERGDSGSPHRFLREKRNLPKLHLEPGKPIVWDGRFRFLNEGMMDFELAAPGRQELADFLKSQNIEIESRKREALLVSPALYREGRLFALLFLQDGEFQQDIHIERHFAIFDHVLPGHDFDLARAVEARIGRICAEMS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio tasmaniensis (strain LGP32)
Length
456 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.169 kDa
Sequence
MTHLIETFTSVLHQSALKPSRLIVAFSGGVDSRVLLELAAQYAQTHGIECCAVHVHHGLSKNADLWAEQCQTWCDALSVSLAVERVSLDINCGESVEKLARDARYQAFQQHIRQGDVLVTGQHIDDQLETFLLALKRGSGPKGLSSMAKVMSFGEAFIVRPLLSVTRLDIEASAHDMGLTWVEDESNQDLRFDRNFIRHQVTPTLTERWPSFRESVCRSAQLCAEQESLLDELLESHLQQALGGCNSKSNSKSNSKSQSLSIDSLSQHSDLLRARLIRMWLSHCNQPMPSQKQLKLIWDEVACAQADANPKLVLNDVEIRRFNNQLYLVQDTKDLSSWKSEILIDENLLLPDGLGEIHLKAVSSGSASHNRDVQRFSLTKANGTLRVIFNPEGVSAHPVGRGHSRKLKKLFQEYQVPSWLRRRTPILMDGDRVIAVLGLFVDKNYEGQDCEALWSK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Length
454 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.089 kDa
Sequence
MKISLTNRVRTTIRERKLFREGNRLVLVALSGGADSVALLCVLRELGYETVAAHCNFHLRGVESDEDAAFVEGLCRDLDVPLHRIDFDTVRYARERSISIEMAARELRYEWFGLLRKELAIEYVAVAHHADDNAETMVLNLCRGTGISGLCGMPYKRNDGIVRPLLDATRDEIEAYLLDQKITYRTDSSNEDTRFRRNLVRHRIMPLLKELNPSLQEALLRTRENLEGVAAFFSKATEDFHNTLRATASISIREVKETPAPFTLLYDLLHPYGFNRDQIREVVTSLDNPPGASFFSSSHRLLRERDRLTVLPLSPKMEVPELFGLKIGDSFLDLPDGKQLSWQRGTPADLDLEGLRLPNTKLLLPLAFVESLQEELGVRRPQRGDHIHPYGMKGCKTVSRFFIDRHVPRRRREEAWLLCQGTEVVWIMGYAADRRFAIDELSDTEEYLLFSFEL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Length
454 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.066 kDa
Sequence
MKISLTNRVRTTIRERKLFREGDRLVLVALSGGADSVALLCVLRELGYETVAAHCNFHLRGVESDEDAAFVERLCRDLDVPLHRIDFDTVRYARERSISIEMAARELRYEWFGQLRKELAIEYVAVAHHADDNAETMVLNLCRGTGISGLCGMPYKRNDGIVRPLLDATRDEIEAYLLDQKITYRTDSSNEDTRFRRNLVRHRIMPLLKELNPSLQEALLRTRENLEGVAAFYSKATEDFHNTLRATSSISIREVKETPAPFTLLYDLLHPYGFNRDQIREVATSLDNPPGASFFSSSHRLLRERDRLTVLPLSPKMEVPELFGLKIGDSFLDLPDGKQLSWQRGTPADLDLEGLRLPNTKLLLPLAFVESLQEELGVRRPQRGDHIHPYGMKGCKTVSRFFIDRHVPRSRREEAWLLCQGTEVVWIMGYAADRRFAIDELSDTEEYLLFSFGL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
Length
454 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.158 kDa
Sequence
MLDTEPDLSTRLFSHIDFTHGAVAAVSGGSDSTALLLLLKHHFDRTGSSAKLLAVTIDHGLRQGSAAEAQAVAKLCAERGIAHRTLTWTGRKPSTGLPAAARDARYHLLAEAARAEGIGLIVTGHTADDQAETVLMRHARDRELADLAGRGLAGMAPATLYDWREWIVRPLLGTRRSALRDFLRREHVGWAEDPTNIDEAFERPRVRAALAGESAGHMENTLRLAGQAAVERGQLGASAANLIRRIASQPSTGLIRLDPALLIADDQAAIYALRILLATAGGAAFLPDQARSAALFVRLKAGFLCATLSRTVVDFRHAGLFLRREARGLPPAATAVDNTIWDGRRHITLNDMSGALLIAPLGAAAARRLAIDDGETPASLIRAALAAEPTLLQAFENLGLPQGEPRLPVFAARPVVSPFARFLPSFDLAPARAVAELIGASPLPASPLGGHSAD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rhizobium meliloti (strain 1021)
Length
453 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.266 kDa
Sequence
MPHAVLDTARNFLRSFITPRRILVAVSGGSDSMGLLVALHSAIAADERRGFSLAACTVDHALRPQSACEAEDVAAFCAALGIAHRICRWEGAKPSTGIQAAARNKRYELLAEAADALGADCIAIGHTRDDQQETVAMRIARGKGDGAGDGQGEGHGGAGMAASMLYGRRIWVLRPFLGLARAEIRSFLQARGVSWIDDPSNANPAFERVRVRARIATSGGMPTPLGNGRQRAASSARAAALIEKRIRVHEALVAEVSARHAGEIDDPDWRRALLTVASVLGGREHMPAFATVQRLSQFLRSGEPGRMTAGRVVFDRRASGLYLYREARNLPVLAVGPGRQGAWDGRFTVKSRGPAVTVAADASGRLWTKRLIDAGLPAGIAKRGSTVAPEIASTDGAGLAFGEAPAQVEYHIGLYDTFLPGFDRIMADAVAVSFGRDRYPAPPVHDVLIEMET
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Persephonella marina (strain DSM 14350 / EX-H1)
Length
452 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.867 kDa
Sequence
MVEKKFLEAVKKYSLISEGDRILVAFSGGIDSTVLTYLLIKFRDHLKISDIYLAHLNHSLRKESDEDQRFCEDFAKKYGLEIFTKKVDIKSLAEKEKKSIEQKAREERYSFFRKVMEERSINRLATGHHLSDLVETMIMWFIQGNRKGIKGFRPKERDIIRPLYLINKDQIENYAREKGIEYRIDITNFETDFLRNRIRHNIIPHIKGINPSLEGSLLTLSYFLSLDDQYLEEESEKISQKFLNGKIELEELLVYDKALVYRAIQNWIYRKTGVYPSYRQIMDIMEIIEKKEGTKSIRLSPEYNLIRRYSTLYIEKVKEKTEPYQYRIKPGEKIFVKEANLYIKSYIETDYTLDKLKDERKKVCFQIESMEDAEFVVRNRRKGDRFIPFGRKKEKKLKDVMIDLKIPSDMRENIPLVVYGNKILWIAGYKRSAYFPVTEKGKKLICFELEEV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1)
Length
452 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.738 kDa
Sequence
MSGSRATAATTTPRSAEPPRGLAVAYSGGRDSTALLHATLIAARDSGLTVHALHVHHGLSARADAWLAHCESQCRRWARRGLPVCFRAMRVQLACRSGDSLEAVARAARYAALRTLAVEQGVALVLLAHHQRDQAETLLLQALRGAGVAGLAGMPRSIERDGITWARPWLARPREAIEAYVRRYRLSYIDDDSNDDPRFARNRLRLQVWPALQAAFPQAEGTLADAARWAQQAAACVADLAALDLAACAATNDVLPLTAWRQLAPHRAVHALRRWLQQAGVTAPTAADLERLMAELPAGAPARWPLKGGELRRYRGELRFVPTPDATREPPAVRETTLALRRGGRYRLPGWGGVLVAERVRAGGVPAAQLAVLSLQPRRGGEQFQGEAGRPARSLKKQYQAAAVPAWARGGPLLYGGDGRLLFVPGLGVDARAMAAPGEPQLALRWEPLPTG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Length
451 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.785 kDa
Sequence
MLLNPLFAQLGENRHVLVGFSGGLDSTVLLHLLVCLRQQLIPELNIRAIHIHHGLNPQADSWVKHCMQQCDQWKIELKVVRVNIDPRQNGIEAAARTARYQAFSANLAAKEVLLTAQHLDDQCETFLLALKRGSGPAGLSAMAAKMPFAHSQLLRPLLAFSREILENYAQAQQLQWIEDDSNQDDRFDRNFLRLNVLPILNQRWPHFAQATARSAGLCAEQEQLLDELLAENLQQLQGPDRSLSIDGLLQASMAKRAAILRRWLASLGAPMPSQSQLQRLWLEVAMARQDAEPQLMIGTRQVRRFRQHLYLLMPLAEITTNYLPWATVKATPNSSIIPLLPEPLWLPADLGVLRFVSAGGQAVRPATVGEEISVRFGLQGDIKIVGRHHSRQSKKVWQELGIPPWQRERIPLLYFGEQLIAAAGVFVTQAGQANENEPCWHLDWDKQLKLG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Length
449 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.34 kDa
Sequence
MVELWQGLGCVFTPEKLLKFITTLTSNSNFCIAYSGGIDSHVLVHAMSHLCQEHPWQLRALHINHGLNPKANDWENHCQQICNRLKIPFQSERVTLSLQPGDSIEAVARKARYAIFQQALSENETLLTAHTENDQAETFLLQLLRGAGVKGLSAMPAKRKLGKGELVRPLLAITRDDLKKYAEKNNLRWVEDDTNLELRFNRNYLRHEVLPILRRRWPEVFAVISRSANHCAEAALLLDQLAESDLQLIQKDSELEILPLLQLTPERQRNVLRRWIYLHGFQLPQTKQLEQIRNDVLLAAHDANPVFSYHTIEIRRHHGKLYLSNALSAHNATPLISWNFSRSLPLPGDLGTLIAEKKKGVGIKTTLDTSKITVRFRQGGEQCQPAGRKETHTLKKLMQEWKIPVWQRDRVPLIYLGDKLIAVVGYCICEGFEAKGEEWGWNVEVQPPK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella abortus (strain S19)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.606 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella abortus (strain 2308)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.606 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella abortus biovar 1 (strain 9-941)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.606 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella canis (strain ATCC 23365 / NCTC 10854)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.546 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLASVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella melitensis biotype 2 (strain ATCC 23457)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.605 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERNNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.605 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERNNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.606 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella suis (strain ATCC 23445 / NCTC 10510)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.546 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLASVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Brucella suis biovar 1 (strain 1330)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.545 kDa
Sequence
MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVKLARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERDNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLASVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.662 kDa
Sequence
MESLYSQFAQVLERYYQSGTKIVLAFSGGVDSRLLLELLSRYQKAYSVDNQSTDSHSFKCHAVYVHHGLSSNADEWAGKCLVWAEQAGITCSVERVSLDTNSGESIELLAREARYQALAKHIQSGDLLLTGQHADDQVETFLLALKRGSGPKGLSSMAESMPFAGGTLVRPLLAIKREQIEAVAKEQGLDWVEDESNQDTRYDRNFLRHRIMPELSERWPSIHQAVQRSASLCAQQEALLDELLLAVFERALQSDFSLSIEELATHSELARARLVRMWLAKLNANMPTQVQLNLIWNEVALAQQDANPKLQLKQGEVRRFQNRLYWVTETVDVTTWQSAIQTDTALLLPEQLGELTLSTNSEQATIAMPPHPELLRVTFNPEGLSAHPTTRSHSRKLKKLFQEYNVPSWLRRQIPILMYQDKVVAVGNLFVDQAFSGQDCELIWRKSL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.324 kDa
Sequence
MMKDGLYDLFCESLESLALKPGQQLVAALGGGADSQTILDLLMRFRQQNPQYQYLAIHLDHSFHPSSADWSSTIEHAAKSYGVKTVFEPLNVPIENRQSKEAAGRESRYRRMAELTEDDAVLLLGQHRNDQIETFFLQLKRGSGPKGLSSMAAIQPWVGSRRLCRPLLSVSKEDILSYAQQQKLTWIEDDTNYDTRIERNFLRHKVVPLLEQRWPQFGNSVLRSAKLCAEQQQVMDELLQEKLYKAQKHKSHFPLSLLSEHSAAMQRALLRVWLQGQEYSLPSYEQLEQIRLQAQSATDDSQMQVQCDGYSVRYFQYALWCDNNTGQLPADCWLAEANVNLGEWGTLSVPDALLTNNNELRLTFSLTSEKLAKPGRQGRKKLKDWLKQAGIPPWLRARRPILELNGKYVWVAGLGWFSYQVIEKTEFDSLQLPEPDWVSSGADSYRQL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.018 kDa
Sequence
MTPIQKFNRQLAAAKLLSPQQTVVVAVSTGVDSMVLLHLLQRLPAAERPRVVVAHVNHHLREQSQMEADYLRQYCQQQNLKLVMADWLPAAHPKSGIEAAGRQFRYHVFAKVMRENRATAVLTAHHANDQVETYLMKLARGGDISQLTGIATSRPFATGRLIRPLLTWSKDQLRNYAAEQHVVYFEDVTNQDVALTRNRIRHRVVPELMTVNPQLLKHVADYQQQLTTLLTAKKQMVTVLLSQVVTATGALVVDQWGALPSQWQLAVFATWLEQQTQQLFTESKLQPLVSWGQRTRPATSRLTVNAAWELYRNAGIIEALPIKKRGKKLMPREKIMVDLNQWQKITATQTVGIFTRVPNVVSQPFWLTEADWPLVWRPWQAGDRIVLKGGGHQLVRRLLIDRKVPAERREQVQVLVNAQGNVLWVVGHKFSYRTTGTQTVFLALKHES
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.494 kDa
Sequence
MELFREILKLNKKYNLIENNDTIVVGFSGGPDSVFLVEMLKKLQYFFNFKIYLVHINHLLRGEDADSDENFSFEYAKKNNLEIFIKRIPVKEIAKEVGKTLEEVGREERYKFFSEIYEKVGANKIATAHNKDDQIETFLFRLIRGTSLQGLEGIKIKNNNIIRPISEIYKKDILEYLNKNEIQYKIDKTNFENEFTRNSIRLNLIPFIEERYNIKFKDKIFSLIEEIRENNQNNSLNLSNYTDSENRIILEKIKFLSDFDKKNLLSLFLNQKNIEVNRNKIDEINSLIKSNGTKKIDLDKSYRIVKDYTHLYIEEKKENFTIVNRVVKLKIPSEQIFDDFKISVNIVKNLDIPKKKNQYLLDALYNDIIEVRYRKEGDRIFLDEKHSKKIKEVFIDQKIPKDMRDRLPIFLYNNKIFWIYNVKKAYIPKINKNESKLIKVLITVEEVK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Azoarcus sp. (strain BH72)
Length
448 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.756 kDa
Sequence
MAVELAGPFAEVLRAAAIGPASRLCCALSGGVDSVVTLDLLTRLQPRFGFTLTAVHVHHGLSPHADAWAQFCARLCAARGLTLAIRRVEVPTDTGQGLESAARARRHAELVALPCDWLVFGHHQDDQAETVLFRLFRGSGLRGLGAMAAVEPGQHAMPGKLRPLLDIGRAGIVAYARAAGLEWIEDESNADCRFTRNALRHKVLPVVQAQFPAVAPTLARTAALLREGADLLDDLARLDENACGGPVLAADVFASLPAARAANLLRWQTARMGARAPSRARLGETLRQLREAPGPLRLPLGDLWCCAYQGRVWLERDDEAPLRAHLWCGESSLGWGAGQVRLSQGGGGAALRVAAGEAMLAPPAPGLRMRLGPGRPTRSFKNLCQEAGIPPWLRPRLPVLWVAGEPAWIGGIGIAAQFQCAEGEQGVVPAWVPASAAQQGQHLGQFDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)
Length
447 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.344 kDa
Sequence
MPLDEFEFSVLKTIQTHHLIFPGHKVLVALSGGMDSMSLLNILLKLRQKLNCEIFAAHLNHMIRENAIRDEQFVYSYCKKAGVKIFVERFDVPKFCADRKIGIEEGARAARYTFLNRIAHENGIDLIALAHNLNDLVETILYRIVRGTGLSGIVCMKLKDENKIRPLLYFKREQIEAYIKRNNIPYVQDETNFNLKYSRNYIRHRIVPALKLLNSDLENAFSQVHFSGMMLENHVKRLIKKYSERIFRCGKRIIFDSKDMDEFEIIELVKYCAGQMNVDLNYRQIQLVVSKLNENSWSIDLSEDIAIKKGFDFFSIEKKCKFMNILKVGKPGVYKFNDWTFELSSEVKSNEYVFIHDQGGVCIRKRKAGEKIAGVKMKDMMIDSKIPAFLRDEMPVVCTIDRIIWVPYVYVDRCFKERKEDSLVLNLLQNPYSCILELRKDERRKMV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
445 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
53.549 kDa
Sequence
MIEKIINQYQKKLFLIAYSGGIDSTVLLYKMLKIKEKNPQIKIRAIHINHNLHPSSKKWEEHCIKICHKYKIPIITKEIKILLKKNIEETLRIKRYNTIYNYLLNDEILLTGHHLNDQCETLFLSLKRGSGPTGLSGMSIENFLGKKRIVRPFLTKTKKELQKWACENNLESIEDFSNFNIDYDRNFIRHKLIPILEQRWPFFLKNCFRTTVICREETKLKNIFLKEKIQNLINFDESLNIQNFKNINKEVCKALIRYWISLKNIKMPSYKTIECIYNEIICSKKDSNPKIIIDKNEIRRYKTSLYFIKIQKDISNIFLFWHNTDKKLLLPEDLGYLIKNDKGFILPSPKKNELINIRFQLEGKILILGREKRRKIKKIWQEHNIPPWLRNKIPLLFYNNRFISAIGLFVIKEKIINKEKEIQKNWKISWINNVHFNRKNFFLFY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
445 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.247 kDa
Sequence
MTTSTPNGHDLPARLLQALAPWRTASTWYVGFSGGLDSTVLLHLLAELAKRANLPALHAIHVHHGLQAIADAWPEHCRQVCQALGVAFESVRVKVEPGASVEQAARQARYAAFTERLGEGDVLLTGQHRDDQAETLLFRLLRGAGVRGLAAMPEQRRLGRGHLARPLLGVSRVELESYARRQGLRWVEDPSNDDQQFSRNFLRSQVLPLLTSIWPHATASLARTAGHLGEAQQLLDELAAQDVANAQATTPFSWLGLPVLNLGPIARLSGARQRNVMRHWLAPLTRLPDSDHWAGWEALRDAAQDARPLWRLADGALHRAQGCIWWLPAGWEQACSEAVNWADPRAPLDLPENGQVSLEGEAPLGDLSVRYRQGAEVMHLSGRGRRDLKRLLNEQAVPAFLRGRWPLLYRDDELLAVANLPGLDGSPNERWRLRWVAPTGDQSLS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Length
445 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.871 kDa
Sequence
MAPTPELSPETLARHLAVLGPASGYCVAYSGGLDSTVLLHLMAALSAARELPLRAVHIHHGLQPQADAWAEHCRQQAAALGVDCLVLPVEVRRDSGEGLEAAARQARYAALASHLQSGEALLTAHHADDQAETVLLHLLRGSGPRGLAGMRAQRPLGRGRLLRPLLPWPRERLRAYGDTHALCWVEDPSNAHVAHDRNWLRHTLWPVLTQRWPDASRRVGRAAGEQAEAEALLRELAGEDLARHPPGPGLAVSVLARLSPARARNLVRHWLLMSGLRPPPRARLEQGLADLIRAGRDRQPVLTWPEGELRRYRDRIHRLPAGGPPPWPGPDREWDLRVPLVVPGVGVLRLVRADEGIAPSLIGAEGLSVGRRRRGERCQLAHDPGHRPLSKRFQEAGIPPWERDRVPILRRGEEVVAIANLGTAKRFTARPGYRLICEEHGPDGG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Agrobacterium fabrum (strain C58 / ATCC 33970)
Length
443 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.126 kDa
Sequence
MPVDARTPNEKTVAPLAAASAFVESLRKPTHILVAISGGSDSTGLLLALQEAKAADDDGLRLSAVTVDHALRPESADEARKVAMLCAELGIPHTTRRWDGPKPASGLSEASRLARYRLIADVAREIGADLVVSGHTIGDQRETVAMRAARSGGSDNLGLSGMADAVLYDAHLWIMRPFLACERQVIRDYVSSRSRHWLDDPSNENIRYERVRVRQTLPHSPIALDDSTAVRRQMLSERTAVFLRERAQVFHAALARLADDDVNPDLPEFRHGLAALIAALGGRSYFPAASSMERVLRFLKTGETGRMTVGRVLLDRRRDGLYIFREQRNLPELQIESSGQAVWDDRFLVKNGSDFPINVAAGRVGTAAQAAALFPSAPSGVVKPAMAGLPQIAAAAEGWVSTPEVAITPRLAPFDLFLPRFDLELANAIANLFGRPAYPQPPV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Length
442 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.163 kDa
Sequence
MANIDERLFVTLAKQLGEYKKILVGFSGGLDSSVLLHLLVNWRNQHNQKIQLRAIHIHHGLNLKADQWIEHCQLICDDWQVEFHSARVTIDARQKGIEAAARDARYQVFKSELQKDEVLVTAQHLDDQAETFLLALKRGSGPAGLASMPSIAVFADTLLLRPLLDYSRNELEKYASKHRLNWIEDDSNQDDRYDRNFLRLHIMPLLNQRWSHFPKAAARSASLCGEQEQLLDELLNESLKELITQDGALGIVSLAVCSEAKRNALLRRWFGYHGMKMPSREQLNRLWYEVALARTDAEPRLQFGKYDVRRYKQKLWLVPQWQSLRETILEWDICNTLVLPDRLGELNIADRGIQVRVPADNERVTIRFGVQGMISIVGRQHSRHSKKLWQELGVAPWLRERIPLLYYNEQLIAALGVFVTKESEAAEGRKMLTMNWHKTLLK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
442 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.655 kDa
Sequence
MPAVPLESRLLQALAPWREAGGWCVAFSGGLDSTVLLHLLAQLARSEALPALSALHVHHGLQAAADGWPAHCQAVCRSLGIPLRVERVQVAVGGSIEQAARDARYRAFQANLGEGQVLLTAQHLDDQAETLLFRLLRGAGLRGLAAMPASRPLGGGRLCRPLLGVSRAELEAYAQAHRLDWVEDPSNQDPRFSRNYLRREIMPRLASHWPQAVAGMARCAAHLREAEDLLAELAAIDLRACRQPSELDWPDWLDLPRIALEPLRRLSAARQRNLLRAWLGQLTRLPDSDHWAGWESLRDAGDDADPIWRLESGELRRGAGRIWWLPADWRAAAGPFVWERPAHPLLLPGNGRLALLGEVPAGPLRVDYRRGGEVLALAGRGRRDLKRLLNEAGVPSFLRGRLPLLFRADELLAVANIPGLDSPREGGWRLSWSPPTNDPGLS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
442 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.025 kDa
Sequence
MGQPSIDLPSRLLRNLKPWLGASHWRIAFSGGLDSTVLLHLLAKLAKNQSIPALSAIHVHHGLQAAADAWPAHCQAVCEELAVPLQVQRVQVQPGASVERAARDARYAAFSAATQANDVLLTGQHRDDQAETLLFRLLRGAGVRGLSGMPATRALGQGSLVRPLLDVTRAELEAYARDHGLRWIEDPSNQDRQFSRNYLRHQIMPLLIGRWPQAHASMARSAAHLREAQGLLDELAQIDLTQASLPSEFEWSGLPSLEFAAIAKLSDARQRNALSHWLEPLTRLPDTDHWSGWVDVRDAGNDASPIWRLADGELHRSAGRLWWLSGEWLRTPVVSGDWHDLSSALRLPDNGRVMFSGQTPVGPLHIRYRQGGEVMDLAGRGHRDLKRLLNERAVPGFVRGRLPLLFRGEELLAVANLPGLDGNALEGWRLHWQPSDEDQGLR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Orientia tsutsugamushi (strain Boryong)
Length
441 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.767 kDa
Sequence
MNIEVNFCHNMEHFGAFEENPKLAIAVSGGTDSLALMLLVKHWNEKVKGEITVLTIDHHLRSESTSEADYVSSICQNIKLQHVTLHWIHKGITGNIQAQARKARYHLLTNYCQEHDILHLITGHHADDIVENFFIRLLRGAGLAGLSSHNIFFVNNVRIIRPLFNITKQDLKKYLEQQNIKWINDPSNNSNKYLRTQVRDLLKSMLISFQNNFTVELLKKRIMLSQMHLTRALDSVNNEIIHYVVYAVKIYSAGFAVIDRKLFRQASPEARYAILSYLLMIVGANTKPQRFSSLQHIILHDIQEYNTYKTLHGCIVEYSIQYIIIYREFGRCYPRSKVVSNSVVWDYRFKVVDNRKNNRMNLTIDYLKKSDYHLIKSYVESNQRNAYFNYSRKILFTFPVIKHLEKVIAIPHIKYYSDKTIQESVSFVFEPKLISRWFHYC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Orientia tsutsugamushi (strain Ikeda)
Length
441 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.539 kDa
Sequence
MNIEVDFCHNMECFGAFEKNPKLAIAVSGGSDSLALMLLVKHWNEKVKGEITILTIDHHLRSESTSEADYVSSICQNIKLQHVTLHWIHKGITGNIQAQARKARYQLLTNYCQEHDILHLITGHHADDIVENFFIRLLRGAGLAGLSSHNLFFVNNVRIIRPLFNITKQDLKKYLEQQNIKWINDPSNSSNKYLRTQVRDLLKSMLISFQHNFTVELLKKRIMLSQMHLTQALESVNNEIIHYVVHVVKIYSAGFAVIDRKLFKKASPEARYAILSYLLMIVGANTKPPRFSSLQRISLHDIQEYNTYKTLHGCIVEYSIEYIIIYREFGRCYPISQVVSNSVVWDYRFKVVDNRKNNHMNLTIDYLKKSDYHLIKSYVESNQRNAYFNYSKKILFTFPVIKHLEKVVAIPHIKYYSDKTIQESVSFVFEPKLISRWFHYC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Proteus mirabilis (strain HI4320)
Length
441 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.613 kDa
Sequence
MELKNCPLINEIKRQIGSHTHILVGFSGGVDSTVLLHGLVCLRDKYQLPLELTAIYVHHGLNSKADDWLTHCEHFCHNWQVSFISERVQVNGKEGGIEQGAREARYQAYRQYLQPNQVLVTAQHQDDQAETFLLALKRGSGPAGLSSMPAKMPFEQGYLLRPLLNITREQIEAYAHEHGLLWIEDDSNQDDRYDRNFLRLHVMPLLTQRWPHFSQAVTRSAALCGEQEALLDELLDVELQQLIDEHQSLDINLLSRCSEIKRNALLRRWFAKCNKSMPSRSQLSRLWQEVALAKADAEPRLRFFQDEVRRYQQRLYLVPVMEELTDRVIEWSLSQPLILPNQLGILAVSRDSGKTICRAPLADEKVTVRFGLTASSLRIVGRDLARSSKKIWQELNIAPWQRTRIPLIYYNDTLIAAVNTFVTLEGNATTEQSITIEWQAS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.63 kDa
Sequence
MIKEIISQYQNKSFLVAYSGGLDSTVLLYKLLEIKKKYYIKIRAIHINHNLTLLSKKWSEHCKKICNINHIPLIVENINIKNKTNNLEEKLRIKRYNIIYNHLFSDEILLTGHHINDQCETFFLSLKRGSGPTGLSSMSFETLFGTKKIVRPFLKKTKIELQTWAKKKKLHWIEDFSNLNIDYDRNFIRNEVIPILEKRWSYFLKNCFRTTIICQQETRLLNDFLRERIYKLIKFDDSLNIENFKNIKQAMCTALIRYWLLLKKIKMPSYKNIQCIYRQMIFSRIDSNPKIILGKHEVRRYKQSLHFIKTQPSLKNTLLFWHKNNIKLTLPNNLGYLIKNNNGTVLPGPKENELINIRFQYEGYVLILGRSKKRKIKKIWQEKNIPPWLRNQIPLLFYNNYFISAIGVFVVNIKNKNRTKCIISWQNDLKSTTNNFFSFY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.029 kDa
Sequence
MDRTEPDDELLQTIVTQTAGCGSILLAYSGGLDSSVLLHLLVTVRQRSGQTIRAAYIHHGLNPLADSWAEHCRQQCERWQVPFSSLAVTVEAQNGGIEAAARTARYQALQVHLKEGETLLTAQHLDDQSETFLLALKRGSGPAGLSAMAANSFLGHHRLVRPLLGFSRLQLEAYAQRHQLRWIEDDSNQDERFDRNFLRRQILPRLTQRWPHFPSAVARSAELCAEQEQLLDELLEESLRTLRQPDGALSIDGLVPLSPVRRFALLRRWLAQQGATMPARDQLQRLWDEVAASRRDAEPILQLNQMQIRRFRQHLYLLPLMPSLKDRVLPWQPTSCPLSLPDNLGTLLLADSGVAVRAPKNGETVSIRFSTSGTVHIVGRAHGRQIKKLWQELGVPPWWRDRTPLLFYNEQLIAAVGRFVTREGQVREHQPLWHIVWERN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Solibacter usitatus (strain Ellin6076)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.423 kDa
Sequence
MFASGARVAVGVSGGADSVCLLHALVELGGLKLSVLHVDHGLRGAESRADAEFVGELAARMGLPFCLREVTLGPGNVEQEGRRARLRFFHEQLAAGNCDRVALGHTRSDQAETVLFRFLRGSGTAGLAGIRPVTAEGIVRPLIELERAEIEEYLRERQIPWREDATNAGEEFARNRIRHGLLPQLAAEWNPALVETLAHTAEFARAEEAYWAGEIDRLSAESLTAGDGCVLIRTESLKALSLAVARRLVRRAIQMAKGDLRGVDFGHVERVVELASAPTGRGRTQVPGLDVRRSFEWLRLGVPFTRKPYSLKPLVPGTTQIPGTRNGISLELIEKSETSVLPWNVYNTEMGCLDWKRLAGSLELRNWRFGDQYQPMGLTGSEKIKTLFQLQRIPVWERAQWPVLTDGESIVWTRRFGPAAGFAAGPESGVVLKLGEVTIR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.913 kDa
Sequence
MDDLYLHFVQQLARYPFRKILLALSGGVDSQVLLALLARGRDEFGWDVTAVHVHHGLSPNADQWAQHCQRCCREVGMACQIEYVQLDVASGESIEKLAREARYRVLAPHVNAQTLLLLGQHADDQLETFLLALKRGSGPKGLAAMAAYAPFAEGHLLRPLLTVSRQHIEAYAKQHKLTWVIDESNADIRYERNFLRHQVTPVLTERWPSIRQAVQRSAELCAEQEALLQEFLAEALKKAITAEGGLSIAVLAEGSEGMRRQLIRAWFAHHRLPMPSRQHTERIWCEVALASEDANPKLKLNHIEVRRFQHCLYLVPPEKDLSGWRSALVPEQRLPLPQGLGHLQLTSKAGGNIKLPDDPSQLWVSFEPQGLEACPVGRVGSRKLKKLFQEYGVPSWRRRQTPILMYQNRVVCVADLFVDRDWSGQDCELVWFKSHDSVPK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.939 kDa
Sequence
MDDLYLHFVQQLARYPFRKILLALSGGVDSQVLLALLARGRDEFGWDVTAVHVHHGLSPNADQWAQYCQRCCREVGMACQIEYVQLDVASGESIEKLAREARYRVLAPHVNAQTLLLLGQHADDQLETFLLALKRGSGPKGLAAMAAYAPFAEGHLLRPLLTVSRQHIEAYAKQHKLTWVIDESNADIRYERNFLRHQVTPVLTERWPSIRQAVQRSAELCAEQEALLQEFLAEALKKAITAEGGLSIAVLAEGSEGMRRQLIRAWFAHHRLPMPSRQHTERIWCEVALASEDANPKLKLNHIEVRRFQHCLYLVPPEKDLSGWRSALVPEQRLPLPQGLGHLQLTSKAGGNIKLPDDPSQLWVSFEPQGLEACPVGRVGSRKLKKLFQEYGVPSWRRRQTPILMYQNRVVCVADLFVDRDWSGQDCELVWFKSHDSVPK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio cholerae serotype O1 (strain M66-2)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.913 kDa
Sequence
MDDLYLHFVQQLARYPFRKILLALSGGVDSQVLLALLARGRDEFGWDVTAVHVHHGLSPNADQWAQHCQRCCREVGMACQIEYVQLDVASGESIEKLAREARYRVLAPHVNAQTLLLLGQHADDQLETFLLALKRGSGPKGLAAMAAYAPFAEGHLLRPLLTVSRQHIEAYAKQHKLTWVIDESNADIRYERNFLRHQVTPVLTERWPSIRQAVQRSAELCAEQEALLQEFLAEALKKAITAEGGLSIAVLAEGSEGMRRQLIRAWFAHHRLPMPSRQHTERIWCEVALASEDANPKLKLNHIEVRRFQHCLYLVPPEKDLSGWRSALVPEQRLPLPQGLGHLQLTSKAGGNIKLPDDPSQLWVSFEPQGLEACPVGRVGSRKLKKLFQEYGVPSWRRRQTPILMYQNRVVCVADLFVDRDWSGQDCELVWFKSHDSVPK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.231 kDa
Sequence
MRCEVAPVLTGTPLLPATPPGPVLLAYSGGMDSSVLLHLLAARPRYRHAGLRALHVHHGLHADADAWAAHCQRTCDALQVPLQIVRVQVARDSGLGLEAAARNARHAAFAQALIAGEWLALAHHRDDQAETFLLRALRASGPEGLAAMRPQRPFASGTLWRPMLAHARADLLAYAHAHRLRWIDDPSNTDPRHDRNFLRSQVLPLLQQRWPQATDALARSAQLSADASALLLQQDMALLPGVLTASGALDLQALRAQSVERRARLLRAWVSAAHAPPLPAHGVAALEQEIDNHAADRHACFAWQQVEVRRWRQCLFLHRPAAAWPSDWHAQWDGAAPLQLPDGAQLRLLGAPGLRFAQPLLVRARQGGERIVLPQRGHSHQLKHLLQALDLPPWERERLPVLWEGAQVLAAGDCIISGTLDAWLQANAAALQWRTAADAN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Borrelia afzelii (strain PKo)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.673 kDa
Sequence
MHFLDDNIQIKIDKFYKKNSLNKNRVIVAFSGGADSTTLLLNLKYYLSNNIIAFYFAHFIRPDNEQNKEIEHVKGFCDLYNIALQIKKCDIDIKSESVRLGVSIEELARKCRYNALENALKENDANYIALAHNENDQIETIIMRFFQGSFLDGLAGIPSVNKNIIRPLLEVSRPEIENFLSLNNIRVFIDSTNSQNLYLRNKVRNNLLPSIEKIFKGYEKCLKRISEFSKEFVNYFEKDEFFPVEKGKYYYSFDLKAFLDFPKYLVFRLIFKILNSEGIVAKISYKALNELFKIEIDRKKNNVLLKTNDFFLEKRHNKINLIFKRDEKFYKPFDFILEVGKWHSLSLGKILLKCLECNAASVSRLKCCSYEFRYKFFKDKLKAKKFFSKFIRCNPIYLMLLALDNRLIGIIDLNTLNLVWSEKSILKKISISLIGGLLKE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Borreliella bavariensis (strain ATCC BAA-2496 / DSM 23469 / PBi)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.695 kDa
Sequence
MHFLDDNIQIKIDKFYKKNSLNKNRVIVAFSGGADSTTLLLNLKYYLSNNIVAFYFAHFIRTDNEQNKEIEHVKGFCDLYNIALQVKKCDIDIKSESVRLGVSIEELARKCRYNALENALKENDANYIALAHNENDQIETIIMRFFQGSFLDGLSGIPGVNKNIIRPLLEVSRLEIENFLSLNNISFFVDSTNAQDLYLRNRVRNNLLPSIEKIFKGYQKCLKRISEFSKEFVDYFEKDEFFPVEKGKYYYSFDLKTFLNFPKYLVFRLIFKILNSEGIVAKVSYKALNEAFKVEINRKKNNVLLKTNDFFLEKRHNKINLIFKRDEKFYKPFDFILEVGKWHSLSLGKILLKCLECNTSSVSRLKCCSYEFRYKFFKDRFKAKKFFSKFIRCNPIYLMLLALDNRLIGIIDLNTLNLVWSEKSILKKISISLIGGLLKE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.472 kDa
Sequence
MHFLDENIQIKIDKFYKKNSLDKNRVIVAFSGGADSTALLLNLKYYLSNNVIAFYFAHFIRSDNEQNQEIEHVKGFCDLYNIALQIKKCDIDIKSESARLGVSIEELARKFRYIALENALKENGANYIALAHNENDQIETIIMRFFQGSFLDGLSGIPSVNRNIIRPLLEVSRLEIENFLSLNNIGFFVDSTNAQNLYLRNRVRNNLLPAIKKVFKGYEKCLKRISEFSKEFADYFGKDEFFPVEKGKYYYSFDLKTFLDFPKYLVFRLIFKILNSEGIAAKVSYKALNEAFKVEINRKKNNVLLKTNDFFLEKRHNKINLIFKRDEKFYKPFDFILEVGKWHSLSLGKILLKYLECNAASVSRLKCCSYEFRYKFFKDRLKAKKFFSKFIRCNPAYLMLLALDNRLIGIIDLNTLNLVWSEKSILKKINISLIGGLLKE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Borrelia burgdorferi (strain ZS7)
Length
440 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.472 kDa
Sequence
MHFLDENIQIKIDKFYKKNSLDKNRVIVAFSGGADSTALLLNLKYYLSNNVIAFYFAHFIRSDNEQNQEIEHVKGFCDLYNIALQIKKCDIDIKSESARLGVSIEELARKFRYIALENALKENGANYIALAHNENDQIETIIMRFFQGSFLDGLSGIPSVNRNIIRPLLEVSRLEIENFLSLNNIGFFVDSTNAQNLYLRNRVRNNLLPAIKKVFKGYEKCLKRISEFSKEFADYFGKDEFFPVEKGKYYYSFDLKTFLDFPKYLVFRLIFKILNSEGIAAKVSYKALNEAFKVEINRKKNNVLLKTNDFFLEKRHNKINLIFKRDEKFYKPFDFILEVGKWHSLSLGKILLKYLECNAASVSRLKCCSYEFRYKFFKDRLKAKKFFSKFIRCNPAYLMLLALDNRLIGIIDLNTLNLVWSEKSILKKINISLIGGLLKE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Length
439 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.339 kDa
Sequence
MRLSLDSFRAGLHPGSTYRVAFSGGLDSAVLLDLMCQVRRVSGIGVRAIHVHHGIQPEADAWSRHCAAVADRYGVALDILQIDGRSRPGDSPEAAARTARYHSLEASLDPGDILVTAQHLDDQAETLLLQLLRGAGLAGLAAMPNAVPFGAGILHRPLLRFGRRDILAYAQERGLSWIEDPSNRDERYDRNFIRRRILPQLAGRWPAVAANLTRSAGHCAEAAGLLDRLADTLMAAATAADEPGTLVLEIVQRLQPDEQRLLLRRWIHKRGLRAPPAKLLERIRKEVVETAGDRTPMIAWAEGTVRRYRHRLHLLPPSADFDASWTAAWSGETPLTLAGNGCLHAALCPGPGIDPDKWRSGRITVRYRRAGDRLEPAGRRGHHELKKLFQEAGLPPWLRDRQPIVCIDGRIASVGGSQWLASEFAGAPERVNIVVHWTP
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Edwardsiella ictaluri (strain 93-146)
Length
439 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.357 kDa
Sequence
MNTLDIQRHIADRLAGRRRLLVAFSGGLDSTVLLHALVQLRASCLPHLRLRVVHVHHGLSHFADQWVDHCESVCYLWQVPLHVLHVQVDTQRNSVEAAARDARYQAIAELIDSRETLLTAQHLDDQCETFLLALKRGSGPTGLSAMAQSMPFFVCEQLRPLLDISREQLTAYAQVHDLSWVEDDSNADARFDRNFLRMRIVPLLRERWPHFSEAVARSASLCAEQEQLLDELLMESLQALMSEDDALSIDGLLPLSEAKRYALLRRWIACFGVMMPTREQLQRLWHEVALAREDAEPQLHLAKCQVRRFRRRLYLLPTLRSLRDEVLRWDPHQPLTLPDGLGELQMGSRGVCVRAPTPGEAVTIRFCAQGVLRIVGRRHSRAIKKIWQELHIPPWERERTPMLYYGESLIAALGVFVTQEGQAVAGATMWNIHWSKDWM
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Length
438 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
52.194 kDa
Sequence
MLKDFIKNTNILNILLAYSGGIDSTFLLYQLLKLKKNNLNFTFRAIHINHQLHPDSEKWSDHCKKICINHNIPIIIKKITINSNKNRIEEIARKKRYQAIYKIIKPKEVLATGHNLNDQCETMLLALKRGSGITGLSSMSYKLNTIYKIKIVRPLLKISREDIKTWIYKHKIHWIEDTSNNDTKHDRNFLRLNIIPKLKNRWPYFEKNCSRSIEILNIEKKILKQEIKKKLNKYLVLNSILNISNFRYIDKNICSIILRHWIKINQNTMPTFKIVKEIYNKVIFSKIDSQPKIIIKNYQIRRYNNHLYWTKKIPRIENIILIWNNTQKKLTLPFQLGNIVQNDFGTTLPHPNNNETINIRFYTSHKVLITKNTKHKKLKTIFKEYKLPPWYRKKIPLIFYNNKFICALGLFVSNTHKKSNNEKNLKLSWISSIHNIIV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Length
438 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.588 kDa
Sequence
MIHTIRLYIEKYRLLSEDRPVLVGLSGGADSVALLGVLVRLGYPCIALHCNFHLRGEESDRDEAFACEFAESLEVPFHKIDFDTISYAGERHLSIEMAARELRYAWFEEMRERLGGQATAVAHHRDDNVETVLMNLIRGTGIRGMSGIRPRNGFIVRPLLCVSREDILAWLADQGYAYMVDSTNLSDAYTRNFIRLNVLPLLEEINPSARNTIARSAEHLSAAETIYIYVLEQARKEVVVSDDRLSIGALMRFPAPETILYELLKEYGFTRLVSDDIFAALTKEPGKLFYSSTHRLLKDRDYLWITSLEKKEKRTFVLDPEKGINHEPIELSFQKLVITIDFPIEKNKRIAYLDYDKLDFPLTLRTWKEGDWFIPFGMKGRKKLSDYFSDHKFSRIEKERTWLLCSGDAIVWVVGERTDNRFRIDESTKRVLIVNFLG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
438 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.826 kDa
Sequence
MESLYQQFSHVLNTYYQPQTKVVVAFSGGVDSRLLLELLRRYREENSLSCHAVYVHHGLSENADIWADKCQVWAKQAGISCSVERVNLDTNSGESIELLAREARYEALARHINRGDLLLTGQHADDQVETFLLALKRGSGPKGLSSMAESMPFAGGTLVRPLLNTKREQIEATAKNIGLEWVEDESNQDTRYDRNFLRHRIVPELSERWPSIHQAVQRSASLCAQQEALLDELLGSVFARALQADLSLSIDELAIHSELAQARLIRMWLSKLNANMPSQTQLRLIWQEVALAQQDANPKLKLKQGEIRRFQNKLYWVTHRADVTSWQGHIQIDEPLILPESLGTLTLSSGSHQPNISLPSHPELLRVTFNPEGLSAHPTTRSRSRKLKKLFQEYNVPSWLRRQIPILMYKDQVVAVADLFVDQTFSGQDCELIWRKPL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
437 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.477 kDa
Sequence
MTLTLNRQLLSSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTLRAIHVHHGLSANADAWVKHCENICQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFARTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTQLIRPLLARTRGELEQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAEQESLLDELLADDLAHCQTPQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALVRIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVAGQSETILPWQTWLQPLELPAGLGSVQLTAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRDTTPLLFYGETLIAAAGVFVTQEGVAVGENGVSFVWQKTLSQVKAG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Xylella fastidiosa (strain 9a5c)
Length
437 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.812 kDa
Sequence
MTVSFPFPRIPDPGVPVLVAFSGGLDSTVLLHCLASQPTQRIHGLEAIHIHHGLHEHADAWTAHCAAFCTQHYIRLHIARVHVSHNSGQGLEAAARTARRAAFAHTLQHGHYLALAHHCDDQAETWLLRALRGSCDGLAAMRPLTPFAAGHLWRPLLTHSRAQLLDYAQQQHLDWIEDSSNADLRHDRNFLRIHVLPLLHQRWPQATAVLARNAALAAANADLLNAEDAVLLPDLLDPDGALDINALTAHPPARRARLLRAWCARAGAPPLPERGVNIIERELLPARHDSAACFTWSHTEIRRWRLRLYLHRPQPPWPPDWQPLWSGITPLILPDGGQLHLESTDHDTVPGFPHPLCVRARRGGERLILPGRTHSHPLKHLLQDIGIPPWRRASMPLLCDGEQILAAGDALLAAPLVTWLHAHRLKLRWQSHNNTCI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
437 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.764 kDa
Sequence
MTVSSPFPRIPDPGVPVLVAFSGGLDSTVLLHCLASQPTQRIHGLEAIHIHHGLNENADAWTAHCAAFCTQHDIRLHIARVHVSHNSGQGLEAAARTARRAAFAHTLQHGHYLALAHHCDDQAETWLLRALRGSCDGLAAMRPLTPFAAGHLWRPLLTHSRAQLLDYAQQQHLDWIEDSSNADLRHDRNFLRIHVLPLLHQRWPQATAVLARNAALAAANADLLNAEDAVLLPDLLDPDGALDINALTAHPPARRARLLRAWCARAGAPPLPERGVNIIERELLPARHDSAACFTWSHTEIRRWRLRLYLHRPQPPWPPDWQPLWSGTAPLILPDGGQLHLESTDHETVPGFPHPLRVRARRGGERLILPGRTHSHPLKHLLQDVGIPPWRRASMPLLCDGEQILAVGDALLAAPLVTWLQAHRLKLRWQYHNNTCI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Onion yellows phytoplasma (strain OY-M)
Length
436 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.652 kDa
Sequence
MKTIKLACSLDANQTYIIAVSGGVDSMALLHCLVAQKIKLQVVHFNHLARPNVWKDKELVQSYCLQNSLCFHYFELNCPQKNFQAQARLLRQQKLMQIATKHQTPFILTAHHLDDLAETILQKITRSSTLLGYSGMQIQTSWQDFIFLKPFLYVPKAKIISYAAFYQIPFLEDYTNQNFTYQRNQIRHQVIPYLKTQTSFLQNIPKYQQTLLQAYNFIRKQTLLFLTKHTNHSCNPPNSFALAPFLNLDLVIQKDIILLLLEQQNITKSFIFIQNIIKGINNPYKPNLSWHLNFEWHLIKDYKHITLMSPAPPLSFALSKPLLCVSTCNLCLACISPSLQSLNYNPQKVSFPLKVRLRQPKDTLKFSFGTKKLKKFLIEKKVPLTQRNNLWLVVDNLDNILFIPHLYINLTLGNQSKIYLAFKNFFTSSNCFSQTN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Serratia proteamaculans (strain 568)
Length
436 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.357 kDa
Sequence
MNNNQLSAQLARQLGAHRHLLVAFSGGLDSSVLLHLLVGLRQQLPDLQLRAVHVHHGLSAFADQWVTHCRQQCVAWQLPLVVQHVQVDSQQGGIEAAARAARYSAFASTLAADETLLTAQHLDDQCETFLLALKRGSGPAGLSAMAAQTSLGNNHLLRPLLGHSRQQLEAYAQQHQLSWIEDDSNQDPRFDRNFLRLQVLPLLNQRWPHFAAATARSASLCAEQEQLLDELLAEQLHNLLDEDRALAIDGLLTCSAARRFALLRRWIALFGVTMPSREQLQRLWEEVALSREDAEPQLQLGQYQFRRFRRRLYLLPLMADLREISLSWSLDDSLMLPDGLGELVSGEGDICLRAPQSQQKVSIRFSAQGKHRILGRAHSRPIKKLWQELGIPPWQRERIPLIYYDDQLIAALGIFVSEAGQTPEGQQPWRLHWRKK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio vulnificus (strain CMCP6)
Length
436 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.637 kDa
Sequence
MDALYSHFSQVLEQQRKANTRLVVAFSGGVDSRVLLELAHRYAQEHLLPCCAVHVHHGLSHNADQWVQSCAAWCQEKNIPLTVERVQLDLTQGNSIEEEARNARYQALRAHINADDLLLTGQHADDQVETFLLALKRGSGPKGLSSMAQQMPFSQGRLIRPLLDVRRQEIERCAHAIGLHWVEDESNQDTRYDRNFLRQQILPALSERWPSFAASVQRSATLCAEQEALLDELLLPVFEQLFGEDQSLAITLLSQQSELARFKLLRMWLAKLGHPMPTRHQLSLIWQQVALSQADANPILQLSQGQVRRFNQRLYLVADNQDLSAWHAPITLNTPLALPDGLGTIELTVSRGFGQIALPEQSEALWISFNPEGLSAHPAERGHSRKLKKLFQEYQVPSWLRRRTPILMYHQQVVAVAGLFVDRQFIGQDCELFWRK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Vibrio vulnificus (strain YJ016)
Length
436 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.662 kDa
Sequence
MDALYSHFSQVLEQQRKANTRLVVAFSGGVDSRVLLELAHRYAQEHLLPCCAVHVHHGLSHNADQWVQSCAAWCQEKNIPLTVERVQLDLTQGNSIEEEARNARYQALRAHINADDLLLTGQHADDQVETFLLALKRGSGPKGLSSMAQQMPFSQGRLIRPLLDVRRQEIERCAHAIGLNWVEDESNQDTRYDRNFLRQQILPALSERWPSFAASVQRSATLCAEQEALLDELLLPVFEQLFGEDQSLAITLLSQQSELARFKLFRMWLAKLGHPMPTRHQLSLIWQQVALSQADANPILQLSQGQVRRFNQRLYLVADNQDLSAWHAPITLNTPLALPDGLGTIELTLSRGFGQIALPEQSEALWISFNPEGLSAHPAERGHSRKLKKLFQEYQVPSWLRRRTPILMYHQQVVAVAGLFVDRQFIGQDCELFWRK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Aster yellows witches'-broom phytoplasma (strain AYWB)
Length
436 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.858 kDa
Sequence
MENIKLACSLETNQTYIIAVSGGVDSMALLHYLVAQKIKLQVVHFNHLTNSNTWKNKELVKNYCLQNSLGFHYFELNCPQKNFQAQARLLRQQKLMQIAAKHRTPFILTAHHLDDLAETILQKISRSSTLLGYSGMQIQTSWTDFIFLKPFLYIPKAKIISYAAFYKIPFLEDYTNQKLTYQRNQIRHQVIPYLKTQTSFLQNIQKYQQTLLQAYNFIRKQTLLFLTKHTNHSCNQPNSIALAPFLNLDLVIQKDIILLLLEQKNITQSFIFIQNIIKGINNPYKPNLSWHLNSDWHLIKDYKHIKLMNPALPLPFALTKPLLCVSTCNLCLVCVCPLIETLNYNSQKVSFPLKVRLRQPKDTLKFSFGTKKLKKFLIEKKVPLTQRNNLWLVVDNLDNILFIPQLYTNLTLGNQFRIYLAFKNFFTSSNCFSQTN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
435 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.552 kDa
Sequence
MDVMQAAGLIPATPPAPVLVAYSGGMDSAVLLHALAATDGYREAGLRAVHVHHGLHADADAWALHCQQQCADLGIALQVVRVQVARDSGSGLEAAARAARHAAFAATLAAGEWLALAHHRDDQAETFLLRALRASGPDGLAAMRPQRPFGPGTLWRPLLGHARADLAAYAQAHAVRWIDDPSNTDPQHERNFLRTQVLPALQQRWPLAADALARSAQLCGDASTLLHDDDVNLLPTVCNSAGALELQPLRSHSPARRARLLRAWVAAAHAPPLPAQGVHALEREIATTQPDRQTCFAWQQTEIRRWRQQLYLLSARATWPAQWQAEWNGDSTLLLPDGAQLQLRGTPGLRFEQPLQVRARQGGERIVLPGRTHSHQLKHLLQQSDLPPWERTRLPLLWAGKTLLAAGDQIVSAKLDQWLRAHAARLQWRSAAPAN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
435 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.552 kDa
Sequence
MDVMQAAGLIPATPPAPVLVAYSGGMDSAVLLHALAATDGYREAGLRAVHVHHGLHADADAWALHCQQQCADLGIALQVVRVQVARDSGSGLEAAARAARHAAFAATLAAGEWLALAHHRDDQAETFLLRALRASGPDGLAAMRPQRPFGPGTLWRPLLGHARADLAAYAQAHAVRWIDDPSNTDPQHERNFLRTQVLPALQQRWPLAADALARSAQLCGDASTLLHDDDVNLLPTVCNSAGALELQPLRSHSPARRARLLRAWVAAAHAPPLPAQGVHALEREIATTQPDRQTCFAWQQTEIRRWRQQLYLLSARATWPAQWQAEWNGDSTLLLPDGAQLQLRGTPGLRFEQPLQVRARQGGERIVLPGRTHSHQLKHLLQQSDLPPWERTRLPLLWAGKTLLAAGDQIVSAKLDQWLRAHAARLQWRSAAPAN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Length
435 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.947 kDa
Sequence
MADSLIEHWPDELSGLFAFEVGFSGGLDSVALLSLLCEARARRPEIGLSAVHVHHGLSPNADAWAAHCQALCDSLRVPLRIERVHVRAGGGESVEAAAREARYQVYRRSASEVIALAHHQDDQAETILLQLLRGGGARALAAMPALRELAPGKLLWRPLLEIPRERLEAYVKARGFAWVDDESNLDTRYRRNLLRHDILPRLERALPHYRSHLARAAMLQADAAAILDEVAREDLQACRTENGLDCGSVLALSAPRRRQTLLAWLDALGWPAPEPGALLEFLRQAEYAERGASPVLRLRQGCLLRFADTLQAWPKAQSEPPASTALLWRGGDAQSLSEWGGELAWERRDAGVPAALLESGAYLAPRRGGEKLSARVGRREVKDLLREAGVPPLLRRRWPLLYGADGELLAVPGIAVSYRAAADGGWWPLWRPARP
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Photobacterium profundum (strain SS9)
Length
435 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.764 kDa
Sequence
MLYSSLRSSLLANIPHSNRFVIALSGGLDSRVLLHLMGRFIQENPQYQCDAVHVHHGLSVNADKWAQQCLQWAFEEKITCHIEHVTLVLGNRISVEQQAREQRYLALSKHVQQGDCLLTAQHADDQLETFLLALKRGSGPAGLASMPESTTFGISYHLRPLLQVTRQSITDYGIAHQLEWVEDESNQDQRYDRNFLRHQITPLLHQRWPGIRKAVSRSAALCGEQEALLNELLASHLSKALHVDQSLKIVELGSERIGKQLIRQWLSLFTVLMPSQAQLQQIWQSVVLAQDDANPQVCWDNHQIRRYKQRLYVVKQWADISLFQQKCELNQACSLPEGLGTLVLTTVKANGILRLPQQHEIVSVRFEPEGIEAKPQGRIGKRKLKKLFQEYEVPSWNRRRTPLVFYNDRLAAVAGLFVTEDFFGEDCDLDWLCNS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacteroides fragilis (strain YCH46)
Length
435 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.333 kDa
Sequence
MIQNRVAQYIEKEKLFCLNDKVLVTLSGGADSVALLRLLLSMGYTCEAAHCNFHLRDKESDRDEAFVRRLCHESGVLLHIEHFDTTQYATKKHISIEMAARELRYEWFETLRKQREASVIATAHHKDDSVETVLLNLIRGTGINGLLGIRPRNGNIVRPLLCLSREEIIAYLQYIDQDYVTDSTNLLDEYTRNKIRLNLLPLMKEINPSVKESIIRTTNYLNDAATLYNQSIGEARKRILTPEGIRIEALLQEPVPEAILFEVLHPLGFNTTQIDNIRQTLDGQPGKVFLGKGWRVIKDRDLLLIEEDTTAEESQPPFRLVMEEYDYTSEFIIPKDKNTACFDADKINKTWEIRKWKPGDVFIPFGMTGKKHVSDYLTDKKFSLSEKEKQWVLCFGEQIAWLIGERTDNRFKVNENTKRVIIVRIVSEHSDFIEE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Length
433 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.412 kDa
Sequence
MLVTRPLLSPEWVARLKQFKKLIVGFSGGLDSTVLLHVLASTPPLSNQLLAVHINHGISGNSLNWQRHCEQLCLDLGIAFIAKAIEFDRSANVEEAARNARYDFFSSLLEDNDCLVLGHHLDDQAETVLLQLFRGAGVDGLAAMQECSNLGAGQLARPFLTCPRVELEHYARIHELKWIEDESNQDTKYSRNYLRHRVMPLLLEKWPGVAGNISRAATHCQQAKANLEVLAIKDCPDLLNATDHLLIEPIKGLEFERITNVLKFWLKKNRIQLPSSKTFHRIIHEIIFAKLDAMPTVSWNQIQVRRFQQHLYLLKADQINLPKAIKWQQFPASLTYPDADIKLSAVKAQKGLMIPKDAQIEIRFRKGGEEIYWHGQTKHLKKLFQEWQIPPWVRDRVPLVYINDQLACVVGYAVSDLFFTTNPLEAWSIVNNS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Length
433 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.393 kDa
Sequence
MRDKISESTQKIFHAVWERIAPFHEMIQSRPAVLSYSGGKDSSILLHFYFWLWIEKKIPAPCIYHLDHSIRFNLEQEKKIFEYADSTFPFSKIFKKKNIPALSRRLGKTLEETGRAFRYKDLKKISDQYEGYIVTGHHSSDYLETILLNLIRGGGWNSLRTLGWYEKNRFRPLFAFSQEEIETILQSEFWKIFEDESNNSDEYLRNRIRSYIIPLLLREGANPDRIYKNFHRIEKPVSKIFSKKNSDHKIPSFLKIDIWVLNDLSQRERKFFIDRYLRSLNLYPTTRNFFRDLTDLLQKENSFSLENKETWFWKSTSSDLYLIPKNSPCLREFRFEPKEMVLKWNGNQKKIPPDLIPDLCPAGAKIRKNGMSIEISEILRQKEIPVPVRKMLPILRGERKVDVICLSLWDPKIGDIVADREVEILPDFQEPGV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Length
433 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.379 kDa
Sequence
MRDKISESTQKIFHAVWERIAPFHEMIQSRPAVLSYSGGKDSSILLHFYFWLWIEKKIPAPCIYHLDHSIRFNLEQEKKIFEYADSTFPFSKIFKKKNIPALSRRLGKTLEETGRAFRYKDLKKISDQYEGYIVTGHHSSDYLETILLNLIRGGGWNSLRTLGWYEKNRFRPLFAFSQDEIETILQSEFWKIFEDESNNSDEYLRNRIRSYIIPLLLREGANPDRIYKNFHRIEKPVSKIFSKKNSDHKIPSFLKIDIWVLNDLSQRERKFFIDRYLRSLNLYPTTRNFFRDLTDLLQKENSFSLENKETWFWKSTSSDLYLIPKNSPCLREFRFEPKEMVLKWNGNQKKIPPDLIPDLCPAGAKIRKNGMSIEISEILRQKEIPVPVRKMLPILRGERKVDVICLSLWDPKIGDIVADREVEILPDFQEPGV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Shigella flexneri
Length
432 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.104 kDa
Sequence
MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTLRAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFARTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTRGELEQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSATLCAEQESLLDELLADDLAHCQTSQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALVRIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSITGQSETIVLWQTWLQPLELPAGLGTVQLTAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRDTTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Escherichia coli (strain K12)
Length
432 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. This enzyme is essential for viability.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.204 kDa
Sequence
MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVALRAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFARTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTRGELVQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAEQESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALVRIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPAGLGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRDTTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length
432 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.26 kDa
Sequence
MNIKTDGWSKKAHIVVAVSTGIDSMSLLYSLLNDYQHTYRKLTCVHVNHGLREQSYEEEAFLREYCHQHHIDIYIKRLDLSDIVADGNSIQQEARQRRYEWFGDIIAQLRADVLLTAHHLDDQFETIIYRLFTGRSTRNSLGMTYESYFNQYKVYRPMLNLKKTEILAYQYANQIPYYEDMSNQDRKYVRNDIRQRIIPAINENPHLNAHQLLKLKDWHDIELQSLKEQAETFINNEVSKSKYLTYSFSRTAFNELNVNIKSVVMDLLFEKLDCHLAMPQHAYDEWFEQIRNDKSQFNIHVTDEWIIQIAYDKLIIMAKSEMDQYILDRICIRKPGTYEFNDYQIDIHPDLPQQLYPLTVRVRQNGDVYKLNGQKGHKKVSRLFIDKKVTLAERQRIPLIINQENAVLAIGDLYVKENFKEFILISNNGDEL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus epidermidis (strain ATCC 12228)
Length
432 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.26 kDa
Sequence
MNIKTDGWSKKAHIVVAVSTGIDSMSLLYSLLNDYQHTYRKLTCVHVNHGLREQSYEEEAFLREYCHQHHIDIYIKRLDLSDIVADGNSIQQEARQRRYEWFGDIIAQLRADVLLTAHHLDDQFETIIYRLFTGRSTRNSLGMTYESYFNQYKVYRPMLNLKKTEILAYQYANQIPYYEDMSNQDRKYVRNDIRQRIIPAINENPHLNAHQLLKLKDWHDIELQSLKEQAETFINNEVSKSKYLTYSFSRTAFNELNVNIKSVVMDLLFEKLDCHLAMPQHAYDEWFEQIRNDKSQFNIHVTDEWIIQIAYDKLIIMAKSEMDQYILDRICIRKPGTYEFNDYQIDIHPDLPQQLYPLTVRVRQNGDVYKLNGQKGHKKVSRLFIDKKVTLAERQRIPLIINQENAVLAIGDLYVKENFKEFILISNNGDEL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pasteurella multocida (strain Pm70)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.74 kDa
Sequence
MLLTQFQAEIAQLPPTQHQFLIGFSGGLDSTALLLLFAKLREKQPHLMLRAIHIHHGLSANADAWVTHCQQICQQVAIPLIVEQVKIDQHKGIEAGAREARYQAIRQHLLPNEMFATAHHQQDQTETFFLALKRGSGLAGLGAMQRKSTLYCLPICRPLLTFTRQMLLDYVKQAGCPWVEDESNTDSRYERNFLRHEVLPRLRQRWPHFDNAVQRSAQHCFEQQQLLNELLHAEFAQHFDKTERTFQLRDFATRSQLKQNALLRLWLAQCGLSMPSKVQLTQLIQDVILAKSDSQPQFQLGEYCVRRYQDTLYLTPHFADLSSLRLPIHIGETLTLPDHLGTLSLQQQAGQLQVIWSHPQHTFTSILPLTEDPIEVRFRYSGKVRLSPTSANKDIKKLWQQHAVPVWLRQRIPLIFYADRFKSAVGYFNAI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus aureus (strain COL)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.292 kDa
Sequence
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYVRNDIRNRIIPAIDENNQLKVSHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIKKPGNYIFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVPQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKKWIIISKNGDE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Escherichia coli O157:H7
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.879 kDa
Sequence
MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGGALRAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFARTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTRGELAQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAETTARSAALCAEQESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALVRIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPAGQGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRDTTPLLFYGETLIAAAGGFVTQEGVAEGENGISFVWQRNA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1131 / NCIMB 11718 / AM63)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.535 kDa
Sequence
MTEFTNFFTKNNIEIKNKKFLLAASGGPDSVALFHMLVNFLPNPSKQLIVAHLDHCLRKDSYLESELLQKLTTAFKIKLIEKSWPVALHPQTGIEAKAREFRYAFLAHTGKKYQVDYLLTAHHGDDLIENILLKFIRSGDVAEMNSLQIVGNLDSMRLLRPLIKYSKDQLLEYDKRNGLDYIEDETNFEDDTLRNRLRHYVVPLLKKETNHLVENAYRFSESAALLSDCQNSFFESLILPIDFGKALRGKKSDLINLNENQLAAFFDYLVYKKWHQRVHFDEIRRRKKATFNKENFQLIFYQDYYYLINRNGLTPIDSKKKKIKLDEKFSLNGKEYLISHDKKIGNLVGYFYGVRTDFLEVGSLPQGSKLRLADGRQTKAKKKFAENGIPLILRPYCLTIWQKENPVYVENVYQNQEYNANFVRYNVYIYL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.251 kDa
Sequence
MTKFTTFFTENNIEIKNKKFLLAASGGPDSVALLKMLVNFLPNPSEQLIVAHLDHCLRDDSFLESQLLQRLTSALKVKLVEKKWPVELHPQAGVEAKAREYRYAFLAKVGRKYQTDYLLTAHHGDDLIENILLKFIRSGDVAEMNSLQIVGNLGSMKLLRPLVKYSKDELLKYDKDHHLDFIEDKTNFEDDTLRNRLRHHVVPLLKKETSHLVKNANHFSESVALLSKCQSDLFDSLPSPINFSKALRGKKEDIARLNTHEAAAFFDYLIYKKWHQRIHFDEIDLNKNVIFNKENFQLLFYQKYYYLINRNELAVIDPKRKLVKLNEKFSFNGKKYLITQDEKSQKLAGYFYGEKAKYLEVGSLPQGSTLKLATGKQTKAKKKFAENGIPLALRPYCLTVWQEENPVYVESVYQNQEYNPNFIRYNVYIYF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Legionella pneumophila (strain Paris)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.2 kDa
Sequence
MTRPLLSPEWVARLKQFKKLIVGFSGGLDSTVLLHVLASTPPLSNQLLAVHINHGISGNSLNWQRHCEQLCLDLGIAFIAKAIEFDRSANVEEAARNARYDFFSSLLEDNDCLVLGHHLDDQAETVLLQLFRGAGVDGLAAMQECSNLGAGQLARPFLTCPRVELEHYARIHELKWIEDESNQDTKYSRNYLRHRVMPLLLEKWPGVAGNISRAATHCQQAKANLEVLAIKDCPDLLNATDHLLIEPIKGLEFERITNVLKFWLKKNRIQLPSSKTFHRIIHEIIFAKLDAMPTVSWNQIQVRRFQQHLYLLKADQINLPKAIKWQQFPASLTYPDADIKLSAVKAQKGLMIPKDAQIEIRFRKGGEEIYWHGQTKHLKKLFQEWQIPPWVRDRVPLVYINDQLACVVGYAVSDLFFTTNPLEAWSIVNNS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Legionella pneumophila (strain Lens)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.339 kDa
Sequence
MTRPLLSPEWVARLKQFKKLIVGFSGGLDSTVLLHVLASTPPLYNQLLAVHINHGISGNSLNWQRHCEQLCLDLGIAFIAKAIEFDRSANVEEAARNARYDFFSSLLEDNDCLVLGHHLDDQAETVLLQLFRGAGVDGLAAMQECSNLGAGQLARPFLTCPRVELEHYARIHELKWIEDESNQDTKYSRNYLRHRVMPLLLEKWPGVAGNISRAATHCQQAKANLEVLAIKDCPDLLNATDHLLIEPLKGLEFERITNVLKFWLKKNRVQLPSSKTFQRIIHEIIFAKLDAMPTVSWNQIQVRRFQQHLYLLKADQINLPKAIKWQQFPASLTYPDANIELSAVKAQKGLMIPKDAQIEIRFRKGGEEIYWHDQTKHLKKLFQEWQIPPWLRERVPLVYINDQLACVVGYAVSDLFFTTNPLEAWSIVNNS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Wolbachia pipientis wMel
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.545 kDa
Sequence
MELELLFQNVVNSSAFYNNQVAVAVSGGVDSIVLLHLMTNWAKKNKLSLPIALTVNHGLRPESQKEADFVVSYAKELGAKESFILNWEKQNIKGNIQLQARKARYKLLAEWCKNNNVKYLLVAHHKDDQAETFLLRLERGSGVDGLSSMDYKSFLNGIDIFRPLLNFSRSEIEKYAKLHRLKWIEDRSNHDLKYRRTLYRNLLKASDNQEILTERICLTALHMKRAAKALMHYTRLAFNDCVNVHDLGYIEIKLSEFYQLPEEIALRLLLYSIMAIASKHYKPRYSSLIAIFNRILQKDSNVNCTLSGCKIRKYGENILIIRESSRIQEITVNLPLNEPTQWDNRFSCTILGNQGCSVIIAPLKKTQKVPEFLKDYNCCPEVFYSLPTVQKDSKVLAYPDVNYNGKNTNDDKVQCIINSTIKQNLVSLISI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Wolbachia sp. subsp. Brugia malayi (strain TRS)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.491 kDa
Sequence
MELESLFQDIMDGFAVYNNKVAVAVSGGIDSIVLLHLITSWAEKRQCPPPIALAVNHGLRPESQEEVEFVVSYAKELGVKKSFILNWKRQNIKGNVQSQARKARYELLTEWCKNNDVKHLFIAHHKDDQAETFLLRLERGSGLDGLSSMDYKSSLNGVCMLRPLLSFSRSRIKKYADFYRLKWVEDRSNQSLKYKRTLYRNLLKASGNQEILTERICLTTLHIKRATKALMHYTRLAFNDCVNVHDLGYIEIKLSEFYKLPEEIALRLLLYSIMVISSKHYKPRYNSLIAIFNKVLQKDNDVHCTLSGCKIRKYGESILIIRESSKIQEISVSLPLNAPIEWDNRFSCTILGNQECSVTIAPLKKTQKIPKFLKDYDCCPEVFYSLPVVLKDGKVLAYLHLNHDRKNINGDEVQCIINSTIKQNLVILAGI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Wolbachia sp. subsp. Drosophila simulans (strain wRi)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.68 kDa
Sequence
MELELLFQNVVNSFAFYNNQVAVAVSGGVDSIVLLHLMTNWAKKNKLSLPTALTVNHGLRPESQKEADFVVSYAKELGAKESFILNWEKQNIKGNIQLQARKARYKLLAEWCKNNNVKYLLVAHHKDDQAETFLLRLERGSGVDGLSSMDYKSFLNGIYIFRPLLNFSRSEIEKYAKLHRLKWIEDRSNYDLKYRRTLYRNLLKASDNQEILTERICLTALHMKRAAKALMHYTRLAFNDCVNVHDLGYIEIKLSEFYQLPEEIALRLLLYSIMAIASKHYKPRYNSLIVIFNKILQKDSNVNCTLSGCKIRKHGENILIIRESSKIQEITLNLPLNEPTQWDNRFSCTILGNQECSVIIAPLKKTQKVPEFLKDYNCCPEVFYSLPVVLKDGKVLAYPDVNYNGKNTNDDKVQCIINSTIKQNLVSLISI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.34 kDa
Sequence
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYIRNDIRNRIIPAIDENNQLKVSHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIKKPGNYFFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVPQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKKWIIISKNGDE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus aureus (strain N315)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.34 kDa
Sequence
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYIRNDIRNRIIPAIDENNQLKVSHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIKKPGNYFFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVPQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKKWIIISKNGDE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus aureus (strain MRSA252)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.309 kDa
Sequence
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLNRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRNGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYVRNDIRNRIIPAIDENNQLKVSHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIEKPGNYIFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVQQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKQWIIISKNGDE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus aureus (strain MSSA476)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.324 kDa
Sequence
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEVYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYVRNDIRNRIIPAIDENNQLKASHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIEKPGNYIFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVQQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKQWIIISKNGDE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Staphylococcus aureus (strain MW2)
Length
431 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
51.324 kDa
Sequence
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEVYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYVRNDIRNRIIPAIDENNQLKASHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIEKPGNYIFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVQQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKQWIIISKNGDE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella agona (strain SL483)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.491 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDREIRRYQSQLWWIKSVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGLLHIVGRHGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella choleraesuis (strain SC-B67)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.348 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAAQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKSVAGQHETTVAWPAWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella dublin (strain CT_02021853)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.428 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHAESWVRHCETVCARWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKSVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGLLHIVGRHGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella heidelberg (strain SL476)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.367 kDa
Sequence
MTTLTLNTSLLSSCRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGECSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITAEGTLRLSPLMLMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKTVAGQHETTVVWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella newport (strain SL254)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.371 kDa
Sequence
MTTLTLNTSLLSSCRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITAEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDREIRRYQSQLWWIKSVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.466 kDa
Sequence
MTTLTLNTSLLSSCRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERMTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQRRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITAEGTLRLSPLMLMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKSVAGQHETTVVWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.424 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITAEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDREIRRYQSQLWWIKSVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella schwarzengrund (strain CVM19633)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.452 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVKRVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVHHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKSVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGLLHIVGRHGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella typhi
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.486 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKTVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGLLHIVGRHGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.405 kDa
Sequence
MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVTLRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAFAQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRETRKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCAEQERLLDELLASDLTDCITAEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDALERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKSVAGQHETTVAWPVWQTPLALPAGLGTVQLVPGGELRRPREEESVSIRFKAPGVLHIVGRNGGRKLKKIWQEQGIPPWRRDTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Wolbachia pipientis subsp. Culex pipiens (strain wPip)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.676 kDa
Sequence
MKLELLFQNIANSFAFHNQIAVAVSGGVDSIVLLHLMTNWAKKNKLSLPIALTVNHGLRSESQKEADFIISYAKELGAKESFILNWEKQNIKGNIQLQARKARYKLLAEWCKNNNVKCLLVAHHKDDQAETFLLRLERGSGVDGLSSMDYKSFLNGIYIFRPLLNFSRSEIERYAKLHQLRWIEDRSNYDLKYRRTLYRNLLKASDNQDVLTERICLTALHMKRAAKALMHYTRLAFDDCVNVHDFGYIEIKLSEFYQLPEEIALRLLLYSIMAIASKHYKPRYNSLIVIFNKILQKGSNVNCTLSGCKIRKYGENILIIRESSKIQEITVHLPLNGSIEWDNRFSCTIFGDQECSVTIAPLKKTQKIPEFLKNYDYCSEVYYSLPTVQKDGKMLAYPDVNYNGKNTDDDKVRFIINSTIKQNLVSLISI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Haemophilus influenzae (strain 86-028NP)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.247 kDa
Sequence
MDLLSDIEKQLQKATAQGFLIALSGGLDSTVLLSLFAKLCQKQPHLPPLSVRAIHIHHGLSPNADSWAKHCQNLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKHLQIQEMLVTAHHLNDQTETFFLALKRGSGLQGLSAMQQQSVLFGMPIFRPLLGFTRPQLEDYAQQEKLNWVTDESNEDNRYDRNFLRNEILPKLRERWAHFDLAVQRSAQHCFEQQQLINDLLSEIFTEHCQIKNQFKLLQFRQYSLAKQTALLRMWLAKNQLEMPSKRQLTQLINDVIFAKEEANPQFQLVNKVIRRYQDSLYLTKPFSDLTKCTLKLEQNMLNLPDDLGNLTVHENEHNLIFYWQDYSVTLEKTNLPISIRFGYSGKVKHHPKRPREDIKKIWQELSVPPWERNRIPLIFYGNELKSAVGFFRVFDEY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Haemophilus influenzae (strain PittEE)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.091 kDa
Sequence
MDLLSDIEKQLQKATAQGFLIALSGGLDSTVLLSLFAKLRQKQPHLPPLSVRAIHIHHGLSPNADSWAKHCQDLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKHLQTQEILVTAHHLNDQTETFFLALKRGSGLQGLGAMQQQSVLFGMPILRPLLGFTRTQLENYAQKEKLNWITDESNGDNRFDRNFLRNEILPKLRERWAYFDLAVQRSAQHCFEQQQLINDLLSEAFAEHCQIKNQFKLCQFRKYSLAKQTALLRMWLAENQLEMPSKRQLTQLINDVVFAKEEANPQFQLVNKVIRRYQDRLYLTKPFSDLTKYCLKLEQNTLSLPDDLGNLSVQENEHNLIFHWQDFSVTLEKTNLPISIRFGYSGKVKHHLKRPREDIKKIWQELSVPPWERNRIPLIFYGNKLKSAVGFFRVFDEY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Haemophilus influenzae (strain PittGG)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.143 kDa
Sequence
MDLLSDIEKQLQKATAQAFLIALSGGLDSTVLLSLFAKLCQKQPHLQILSLRAIHIHHGLSPNADSWAKHCQDLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKHLQTQEMLVTAHHLNDQTETFFLALKRGSGLQGLGAMQQQSVLFGMQILRPLLGFTRPQLEDYAQKEKLNWITDESNKDNRFDRNFLRNEILPELRARWAYFDLAVQRSAQHCFEQQQLINDLLSEAFAEHCQIKNQFKLCQFRKYSLAKQTALLRMWLAENQLEMPSKRQLTQLINDVVFAKEEANPQFQLVNKIIRRYQDRLYLTKPFSDLTKYCLKLEQNTLSLPDDLGNLSVQENEHNLIFHWQDFSVTLEKTDLPISIRFGYSGKVKHHPKRPREDIKKIWQELGVPPWERNRIPLIFYGNELKSAVGFFRVFDEY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.053 kDa
Sequence
MDLLSDIEKQLQKATAQAFLIALSGGLDSTVLLSLFAKLCQKQPHLPPLSIRAIHIHHGLSPNADSWAKHCQDLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKYLQTQEMLVTAHHLNDQTETFFLALKRGSGLKGLGAMQQQSVLFGMPILRPLLGFTRTQLENYAQKEKLNWITDESNEDNRYDRNFLRNEILPELRERWAHFDLAVQRSAQHCFEQQQLINDLLSEIFTEHCQIKNQFKLCQFRQYSLAKQTALLRMWLAENQLEMPSKRQLTQLINDVIFAKEEANPQFQLVNKVIRRYQDSLYLTKPFSDLTKCTLKLEQNTLNLPDDLGNLTVQENEHNLIFYWQDYSVTLEKTNLPISIRFGYSGKVKHYPKRPREDIKKIWQELGVPPWERNRIPLIFYGNELKSAVGFFRVLKSS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia akari (strain Hartford)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.074 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKIAVAVSGGSDSVALLYLANIWAEKNNIELSVISVDHNLREQSKQETYYVQNISNSLNRKHYSLSFDHQNNFSNLQERARAGRYDLMTNLCLEFDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIQIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNIIRQKLAKGAGYIKAEIILQQLKINDLLDNKFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQFRAARFYSVEPILKLITQDVNFKNTLHGCVVKRIQNELLIYREFGKKLPESKILLDKSIIWDNRFCITKNQENPDCVITYLSLEDYKTIKKQLDLAHLKDLSCKNHNAILFTLPIIKILEKVIAIPHISYYDNDMQNFEVSFAPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia bellii (strain OSU 85-389)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.074 kDa
Sequence
MLYEKFEHNINNLIGGFGLSKIAIAVSGGSDSVALLYLANIWAKKNNIELFVLSVDHNLRDQSKQEIEYIQNTANDLGLKFYSLFFDHQNNFSNLQERARKGRYDLMTSLCQKLDILVLLTAHHEDDYIENFCLRLERKSGVFGLSSSSVNWHNNTQIIRPLFNIPKSELVNYLATNNIKWFEDQSNLSTKYRRNTIRQKLAKEEVYIKDDIITQQIKVNELIENKFKPELISAIAESVKISEYGFAFLDLIKFSGFSQEVRVQLINFLLIIISGQQRSARFYSVEPILKLIRQSLDFKNTLHGCVIKRMQNKLLIYREFGKKLPESKLLLDKQLVWDNRFRITKNHDIENCVATYLSLEDYKIIKEKLDLEVLKNLSCGNHNAILFTLPIVKILEKVVAIPHISYYDNDIKSFNVSFAPDFTSRFTHFY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia bellii (strain RML369-C)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.073 kDa
Sequence
MLYEKFEHNINNLIGGFGLSKIAIAVSGGSDSVALLYLANIWAKKNNIELFVLSVDHNLRDQSKQEIEYIQNTANDLGLKFYSLFFDHQNNFSNLQERARKGRYDLMTSLCQKLDILVLLTAHHEDDYIENFCLRLERKSGVFGLSSSSVNWHNNTQIIRPLFNIPKSELVNYLATNNIKWFEDQSNLSTKYRRNTIRQKLAKEEVYIKDDIITQQIKVNELIENKFKPELISAIAESVKISEYGFAFLDLIKFSGFSQEVRVQLINFLLIIISGQQRSARFYSVEPILKLIRQSLDFKNTLHGCVIKRMQNKLLIYREFGKKLPESKLLLDKQLVWDNRFRITKNHNIENCVATYLSLEDYKIIKEKLDLEVLKNLSCGNHNAILFTLPIVKILEKVVAIPHISYYDNDIKSFNVSFAPDFTSRFTHFY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.326 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKIAAAVSGGSDSVALLYLANIWAEKNNIELSVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIQIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNIIRQKLAKGEDYIKADIILQQLKINDLLDNKFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQFRAARFYSVEPILKLITQDVNFKNTLHGCVINRIQNELLIYREFGKKLPESKILLDKSVIWDNRFRITRNQETPNCFVTHLSLEDYKMIKKQLDLEPLKNLSCKNHNAIIFTLPIIKILEKVIAIPHISYYDNDMWNFEVSFAPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia prowazekii (strain Madrid E)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.474 kDa
Sequence
MLYEKFEYNINNLIGNFGLSKIAIAVSGGSDSISLLYLANIWARKNNIELFVISVDHNLRPQSKQENYYIHTISSNLNRKYYNLSFDHQNNFSNLQERAREGRYDLMTNLCLELDVLVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNIHWYNNIQIIRPLYNIPKSELVEYLVNHKIKWFEDESNLSDKYRRNIIRQKLFKEENYIKAEISLQQLKTNKLIEDELKPALISAIAEAVKIFEYGFTFLDLVKFDKFLNEVKAQIINFLLIMISGQSRSARFYSIAHILKLISQDINFKNTVHGCVIKRIQNELLIYREFGKKLPKSKILLDKSVIWDNRFCITKNQKTPDCVITYLSLADYKAIKKQLDLKHLKNLSCKNHNAILFTLPIIKILEKVIAIPHISYYDNDVWNFEVSFAPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Length
430 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.397 kDa
Sequence
MLYEKFEYNINNLVGNFGLSKIAIAVSGGSDSVALLYLANIWAEKNNIELFIISVDHNLRAQSKQENYYIQSISNNLKRKYYNLSFDHQNNFSNLQARAREGRYDLMTNLCLELDVLVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNIHWYNNIQIIRPLYNIPKSELVKYLVTNKIKWFEDESNLSDKYRRNIIRQKLFKEENYIKAEISVQQLKTNKLIEDELKPELISAIGEAVKIFEYGFTFLDLVKFDKFSNEVKVQIINFLLIMISGQSRSARFYSIAPILKLISQNVNFKKTVHGCVITRIQNELLIYREFGKKLPKSKILLDKSVIWDNRFCITKNQETPDCVITYLSLEDYKVIKKQLDLKHLKNLSCKNHNAILFTLPIIKILEKVIAIPHISYYDNDMWNFEVSFAPNFVSRFTHFC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pyogenes serotype M1
Length
428 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.546 kDa
Sequence
MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQDKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYAFFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPFLTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLLFQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTAKQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKEEKMLEYDSNLCYRDYYFSFMPKSNEDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Length
428 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.472 kDa
Sequence
MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQDKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYAFFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPFLTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLLFQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTAKQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKDEKMLEYDSNLCYRDYCFSFMPKSNEDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Length
428 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.783 kDa
Sequence
MLLSRFQQQLTQHFPQQPNVLLSLSGGIDSVVLLDLFSRTTTPLRAIYIHHGLSANADNWADFCEALCKQYNIPFILQKVTVDKSTGIEAGARTARYKAIAEHIQANEILATAHHLNDQAETFLLALKRGSGVKGLSAMQIVSHRQNMTIFRPLLSTTKKEIQQYAKQQQLCWIEDESNQNNHYDRNFLRNQILPLLLQRWPQFNQMIARSAKHCTAQQQLLAELLDEELHRYANIDEKSLQISQFKHFSPLKQQQLIRLWLAKCDIPMPTSAQFEQIISGFLNSATDKHPQLRLKNWTLRRFQKTLYLTPQLANTQHFCQILSVNQTIDLPDNLGQLTRQPQQIIYQQTHKTNRLLLPESLRTVPLTIKLHQTGKVKRYQHPHSEEMKKLYQQAKIPVWQRTRTILVFFEDQLVDLLTQHKNQQNND
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
Length
428 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.487 kDa
Sequence
MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQDKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYAFFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPFLTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLLFQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQIAKQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKEEKMLEYDSNLCYRDYYFSFMPKSNEDQGQVNIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIVGEQDGEIIFVLVGDKTYLRKACKHDIMLAKLYIDKLEKG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pyogenes serotype M18 (strain MGAS8232)
Length
428 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.499 kDa
Sequence
MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQDKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYAFFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRYLSGIKSVQPFANGQLIRPFLTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLLFQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQIAKQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKDEKMLEYDSNLCYRDYYFSFMPKSNEDQGQVNIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIVGEQDGEIIFVLVGDKTYLRKACKHDIMLAKLYIDKLEKG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pyogenes serotype M3 (strain SSI-1)
Length
428 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.472 kDa
Sequence
MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQDKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYAFFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPFLTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLLFQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTAKQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKDEKMLEYDSNLCYRDYCFSFMPKSNEDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermosipho africanus (strain TCF52B)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.205 kDa
Sequence
MLTLLEKFIQKIEEYNLIEENDRILVAVSGGVDSSVLLNLLARVQEYFKFSIFCATVDHGIRKESKEEVKFVYNMAQSLNVECFIKEFDVPLYAKENKLSIEEAARKLRYKFLNEIAKKINANKVATAHNLNDLAETVLFRLARGTGPFGIYGMKPRNGNIIRPLLFFERKEIEQFATENKIPFVVDKTNFDTKYTRNFIRHKIIPIFKEINPLFEQAVLRFVENVWELDSFVKDKLNVETFEFEGRIFFKVPKDEYILVEFIRRKTMEHFGRAPDKEKLDRLKKNLYKTSFKISFWGDYGVEISYGYGVLGKFIEHMNYECSMDCQNNVNFGPFVVKFGNNGIIFKKMNLTIRNYRFGDKTKGGKKLKEIFVEKKVPSFIRRIIPIFVDEDGYVFYIPNVFLDRDYLSKEENGISIKVEMKGGFWF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Histophilus somni (strain 2336)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.991 kDa
Sequence
MDLLQQLQNQLNQFPSHTKLLLGFSGGLDSTVLLSLLAKLRKKQPHLSLRAIHIHHGLSQNADNWAIHCRQICQQLDISFLCEKVTINPRKGIEADAREARYQAIANHLQDNEILVTAHHQQDQTETFLLALKRGSGLQGLGAMQIQSVVFNLPIFRPLLHCTKQQLEQYAKTEKLSWIEDESNADNRYERNFLRNDILPKLRQRWQSIDNAVQRSAQHCFEQQQLINELLNDEFNKIYDKFDRTLSIANFATYSILKQKALLRTWLQHLHILMPSTIQLDNIMRNMIQAQEDRNPTCRLGNQVLRRYQKRLYATPILQDLSHIRLDIQANECINLPDNLGEICLLTKNEHLQVTWQNKQILLPLTQEKIEIRFRYSGKVKLPQGFHQEMKKCWQDHNVPVWQRTRIPLIFYGNKFKSAVGFFNNCE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus equi subsp. equi (strain 4047)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.669 kDa
Sequence
MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQAKLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQFFEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFLTVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLLQAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQKQGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTDKGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQAGVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus equi subsp. zooepidemicus (strain MGCS10565)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.583 kDa
Sequence
MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQAELQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHFRYQFFEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFATGQLIRPFLTVSKEELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIALSAESRLLLQAFDDLTKGLAFHRLDCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQKQGIYPIKNTYCLLIEKESFVIKKIIPKTDLNRESKMVSYGDPLDYGGYRFAFSGDLTDKGHDIVIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTNEQRQNAIVGEQAGVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Haemophilus somnus (strain 129Pt)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.089 kDa
Sequence
MDLLQQLQNQLNQFPSHTKLLLGFSGGLDSTVLLSLLAKLRKKQPHLSLRAIHIHHGLSQNADNWAIHCRQICQQLDISFLCEKVTINPRKGIEADAREARYQAIANHLQDNEILVTAHHQQDQTETFLLALKRGSGLQGLGAMQIQSVVFNLPIFRPLLHCTRQQLEQYAKTEKLSWIEDESNADNRYDRNFLRNDILPKLRQRWQHIDKAIQRSAQHCFEQQQLINELLNDEFNKIYDKFDRTLSIANFATYSILKQKALLRTWLQHLHILMPSTIQLDNIMRNMIQAQEDRNPTCKLGNQVLRRYQKRLYATPILQDLSHIRLDIQANECINLPDNLGEICLLTKNEHLQVTWQDKQILLPLTQEKIEIRFRYSGKVKLPQGFHQEMKKCWQDHNVPIWQRTRIPLIFYGDTFKSAVGFFDNFE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus equi subsp. zooepidemicus (strain H70)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.583 kDa
Sequence
MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQAELQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHFRYQFFEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFATGQLIRPFLTVSKEELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIALSAESRLLLQAFDDLTKGLAFHRLDCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQKQGIYPIKNTYCLLIEKESFVIKKIIPKTDLNRESKMVSYGDPLDYGGYRFAFSGDLTDKGHDIVIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTNEQRQNAIVGEQAGVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.063 kDa
Sequence
MINLTPWLNAPTWYVAFSGGLDSTVLLHLLAEYARNHASPPLRAIHIHHGLQAAADAWPAHCQAICDNFDVELQVIHVQVSPGASLEQAARDARYAAFRQVLGPGDILFTGQHRDDQAETLLFRLLRGAGLRGLAAMPGQRALGQGSLVRPLLACSRQHLQEYAQAQGLTWIEDPSNVDTQFARNYLRGEVMPHLQQRWPQASQNFARAAEHLGEALGLLDELAQEDLALAGKGAPLAWPGLDSLDLAALLALSPARQRNALQYWLSQRTRLPDTRHWAGWADLRDAGADARPVWRLADGRLVRSHGRIWWLSGDWLQQPAGSLAWPDPDGPLRLPGNGCVRLVGAAVPSGLRIAYRQGGEMLEVPGRGRRDLKRLLNEQQVPHFLRSRLPLLYHGECLLAVANLPGLVQADCQLHWQLPTNAQGLS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / 130Z)
Length
427 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.556 kDa
Sequence
MSLLSEFQAQLQHSRYLIAFSGGADSTALLALFAKSRQNRPHLQLRAIHIHHGLNVAANDWAAHCRRICEKLEVPLIIERVEINKKSGIEQGAREARYAAIRCHRHADEIVATAHHLQDQTETFLLALKRGSGIKGLGAMQRESRLYGMPIFRPLLPFGKTELENYLRAQSLDWIEDDSNADNRYDRNFLRNRILPVLRRRWTDFDLAVSRSAQHCYEQERLIRELLTPAFEKNYRKTDRTFALSDFAGYSPNKQNALLRMWLTACRVPMPEKMQLAQLIRDVVFAKPDAVPQFVLGEQVIRRYQNRLYLTPHYADVTDFRARLTVNKTVELPDNLGRLHLIKNTKNLTALWQYEDWQYSADFPLGEQQISVGFGYAGKVKLHARDMSRDIKKVWQKYAVPPWRRTRIPLIFVDGKLKSAVGFFDVF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Length
426 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.476 kDa
Sequence
MKDCFPQGLNGKKTAVALSGGLDSVVLLHLLVCAGKRAGFVPEALHIHHGLSPRADDWADFCRNYCDMLGVGLETVKVCVEKNGLGIEAAARQKRYAEFAEKGFDVLALAHHRDDQIETFMLAVARGGGLRALAAMPAVRPLGENGIIWRPLLPFSRQDIWDYARKHGLPNIEDESNTDTAYLRNRFRHRILPELSAQIPHFGRHVLNNVRALQEDLALLEEVVVQDCRWVCGAGYFDTARWLTFSPRRKTHILRNFLKENGIPVPNQNALADIARVLTEAKTGRWNLQGFELHHYAGRLFVFASEQLAKPAFLKDGTISGNLKKILTEHRFVLKRHPFGLPEAMLEQDGILRTVAASDTLAVGGIHKNVKKILQGKRVLPFLRPIWPLVADSGNRPLALANCCADFQISVSDGILPVHPDFPILF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
426 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.732 kDa
Sequence
MKDCFPQGLNGKKTAVALSGGLDSVVLLHLLVRAGKKGGFIPDALHIHHGLSPRADDWADFCQNYCDMLGVGLETVKVCVEKNGLGIEAAARQKRYAAFAEKGFDVLALAHHRDDQIETFMLAVARGGGLRALAAMPAVRPFGEKGIIWRPLLPFSRQDIWDYAQKHGLPNIEDESNTDTAYLRNRFRHRILPELSAQIPHFGRHVLNNVRALQEDLALLDEVVVQDCRWVCGAGYFDTARWLTFSPRRKTHILRHFLKENGIPVPNQNALADIARVLTEAKTGRWNLQGFELHHYAGRLFVFRLEKTDKLRFLKDRQISGNLREILTGQGFVLKRHPFGLPEHLLEQDGILRTVAASDTLAMGGIHKDVKKILQGKRVLPVLRPIWPLVADSGNRPLALANCCADFQYSVSDGILPVHPDFPILF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mannheimia succiniciproducens (strain MBEL55E)
Length
426 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.558 kDa
Sequence
MSDIFNQFQQQIYQQKILIAFSGGLDSTALLALCKKLQENRPHFQFRAIHIHHGLSPNADKWALHCENICRQFSIPLIVEKVRVDKSNGIEAGAREARYHAIANHLNIDEVLATAHHLNDQTETFLLALKRGSGVQGLSAMQKESVVFNLPIFRPLLQFTRAQLEDYVKSQKINWIEDESNEDNSYDRNFLRNIILPKMKTRWAHFDQAVYRAAQHCFEQTQLVNELLEDEFQKIFEKNDRTLSVKLFDRYSYIKQKALLRLWLARLQLAMPSQKQLEQLIRDVIFAKPDAIPQFKLANQVIRRYQQKLYLTADFADLTDVAVPLKISQTVPLPDGLGHISLREQSGCFVFSWRHYQVQLPPCKQPIEIRFAYSGKVKLHKNGVNQDIKKVWQNLNVPPWLRNRTPLIFYGDQLKSAVGFFKVFDC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Enterobacter sp. (strain 638)
Length
426 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.584 kDa
Sequence
MTSSVIAQSVFPYRQLLVGFSGGLDSTVLLHRLMLWREQEPDVQIRAIHVHHGLSSNADHWVAHCESLCKSWHIPLIVERVKLRDEGLGTEAQARKARYLAFEKTLQAGEALVTAQHLDDQCETFLLALKRGSGPAGLSAMPVRTEFAGSQLIRPLLGETRTSLEKWAQDYNLCWIDDESNQDDRYDRNFLRLRVLPLLSERWPHFADATARSAALCAEQESLLDELLTEELASVISTEGRLRIEPLEAMSPVRRAALIRRWLAAHHAQMPSRTMLNRIWEEVALAREDATPRLHLGGFEVRRYKGELWWVKYQPTMIDQIIEWRDPSVTLMLPQGSVCFADGGHIRLPNPDEQVTIRFKACGILHIVGRHGGRKLKKIWQEYNIPPWLRDTTPLLFYGETLIAAAGVFVTKEGWIEKGVQLEWKA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Length
426 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.468 kDa
Sequence
MIQQRVIRYIEKEHLFLPDDKLLVALSGGADSVALLRVLHTAGYQCEAAHCNFHLRGEESNRDERFVRQLCQKYGIRLHITDFNTTQYATEKRISIEMAARELRYNWFEKIKEECGAHVIAVAHHQDDSVETMLFNLIRGTGITGLLGIRPRNGAIVRPLLCINREEIIRYLQQIGQDFVTDSTNLEDEYTRNKIRLNLLPLMQEINPSVKNSLIETSNHLNDVATIYNKVIDEAKTRIITPEGIRIDALLDEPAPEAFLFETLHPLGFNSAQIKDIANSLHGQPGKQFVSKEWRVIKDRNLLLLETIRPEDESTLPYQLIKEEREFTPDFRIPREKETACFDADKLNEEIHCRKWQAGDTFIPFGMTGKKKISDYLTDRKFSISQKERQWVLCCGERIAWLIGERTDNRFRIDETTKRVIIYKIV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.238 kDa
Sequence
MRDKISESTRNIFDTVWKRIFPFHEMILSRPAVLSYSGGKDSSLLLHFYFWLWAEKKIPVPCIYHLDHSIRFNLEQEKKILDYTESTFPFPNLFKKKNIPALSQKLGKTLEETGRAFRYKDLEKISNQYEGYIVTGHHSTDYLETVFLNLIRGGGWNSLRTLGWYEKNRFRPLFAFTEDEIKTISQSESWPIFEDESNQSNEYLRNRIRNYILPLLLQEGADPDRIYKNFHRMEKPTSKILLKEVSSHKTPSFLKIDVWVLNDLSERERKFFIDRYLRSLNLHPTTRNFFQDLMDCLKKMNSFGIENKEAWFWKSSSYDLYVIPKNSLCLKKFKLESKNMILKWNGSQKKISPGFIPGLCSPGAKIRKNGMSIEISEILRQKEIPVPVRKMLPILYREGKVDVICLSLWDPRLGDIVADRSRNFI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.238 kDa
Sequence
MRDKISESTRNIFDTVWKRIFPFHEMILSRPAVLSYSGGKDSSLLLHFYFWLWAEKKIPVPCIYHLDHSIRFNLEQEKKILDYTESTFPFPNLFKKKNIPALSQKLGKTLEETGRAFRYKDLEKISNQYEGYIVTGHHSTDYLETVFLNLIRGGGWNSLRTLGWYEKNRFRPLFAFTEDEIKTISQSESWPIFEDESNQSNEYLRNRIRNYILPLLLQEGADPDRIYKNFHRMEKPTSKILLKEVSSHKTPSFLKIDVWVLNDLSERERKFFIDRYLRSLNLHPTTRNFFQDLMDCLKKMNSFGIENKEAWFWKSSSYDLYVIPKNSLCLKKFKLESKNMILKWNGSQKKISPGFIPGLCSPGAKIRKNGMSIEISEILRQKEIPVPVRKMLPILYREGKVDVICLSLWDPRLGDIVADRSRNFI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.841 kDa
Sequence
MIEQQFLKQCKEKAYFIEHQRVLLAISGGLDSMTLLNLLYKYQKELDIELILAHINHKQRIEADQEEKQLKEIAQKLGVKILTSSFSGVFSEKSARDFRYNFFKKVMQEEDCTALVTAHHADDQAETIFMRILRGSRLRYLSGMKDRQPFGGGELIRPLLEFSKTDFPTVFHFEDASNFENTYFRNRVRNHYFPLLETENPRIKQAIINLGTEIAQLQKALSDLTKDLNQTDLQTFRKQKREVQVFLLQEYLEKFPDLQLSKAQFDEILHILNTKANYHHYLKNQYELIQDYQTFKIQKIGPKSDSKKDAILLQFEDIIELDNFCFSFGKELVGGVVQMIPVSRKTSIVLRHRQSGDRIVLNGHHKKLARYFIDEKYSLQERDEAIIVEQFNEILGIAGIVTSDLSKNSKRDIMKDILYIKKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.966 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKFKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae serotype 19F (strain G54)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.903 kDa
Sequence
MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain 70585)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.881 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEGESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain Hungary19A-6)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.881 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEEEDEFVLHYQNQVAYQGYLFSFGLPLEGESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.86 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNTNVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.906 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain CGSP14)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.903 kDa
Sequence
MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.966 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKFKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus sanguinis (strain SK36)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.733 kDa
Sequence
MIKQEFLKKMQEKKYFQDHRKVLIAVSGGLDSMTLLQLLIVSQKELAIELAIAHVNHKQRPESDQEEKALVKIAEQLGVKIFTSSFSGNFSENAARQFRYDFFGKVMQEGHYTALVTAHHADDQAETVFMRLLRGARLRHLSGMKAVQPFACGELIRPLLTFHKSDFPDIQHFEDSSNFQNDYLRNRIRNLYLPDLEKENPQFKDSLRYLGKEIEDWQTALSHLTRDLDIENVQVFHQQIPQVQRFLLQNYLENFSGLNLSKQQFEEVLNILQTKANYQHTLKKDYELVKDYQRFEIRKISRKPDLKMDSILLEFENLIEFGYYRFSFGIPLSGENIQKIFVSRETSLTLRFRKEGDSILLNGHHKKLRRLFIDKKVSFEERNSSVVVEQNHQILAILNIAISDLSKALKSDIMSTVLYIQKIDG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain JJA)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.872 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain P1031)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.847 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEGESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus pneumoniae (strain Taiwan19F-14)
Length
425 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.846 kDa
Sequence
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus agalactiae serotype III (strain NEM316)
Length
424 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.933 kDa
Sequence
MYNTILKDTLSKGLFTAHQKVLIAVSGGIDSINLLQFLYQYQKELSISIGIAHINHGQRKESEKEEEYIRQWGQIHDVPVFISYFQGIFSEDRARNHRYNFFSKVMREEGYTALVTAHHADDQAETVFMRILRGSRLRYLSGIKQVSAFANGQLIRPFLPYKKELLPNIFHFEDASNASSDYLRNRIRNVYFPALERENNQLKDSLITLSEETECLFTALTDLTRSIEVTNCYDFLRQTHSVQEFLLQDYISKFPDLQVSKEQFRVILKLIRTKANIDYTIKSGYFLHKDYESFHITKIHPKTDSFKVEKRLELHNIQIFSQYLFSYGKFISQADITIPIYDTSPIILRRRKEGDRIFLGNHTKKIRRLFIDEKITLKEREEAVIGEQNKELIFVIVAGRTYLRKPSEHDIMKGKLYIENLEKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Length
424 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.933 kDa
Sequence
MYNTILKDTLSKGLFTAHQKVLIAVSGGIDSINLLQFLYQYQKELSISIGIAHINHGQRKESEKEEEYIRQWGQIHDVPVFISYFQGIFSEDRARNHRYNFFSKVMREEGYTALVTAHHADDQAETVFMRILRGSRLRYLSGIKQVSAFANGQLIRPFLPYKKELLPNIFHFEDASNASSDYLRNRIRNVYFPALERENNQLKDSLITLSEETECLFTALTDLTRSIEVTNCYDFLRQTHSVQEFLLQDYISKFPDLQVSKEQFRVILKLIRTKANIDYTIKSGYFLHKDYESFHITKIHPKTDSFKVEKRLELHNIQIFSQYLFSYGKFISQADITIPIYDTSPIILRRRKEGDRIFLGNHTKKIRRLFIDEKITLKEREEAVIGEQNKELIFVIVAGRTYLRKPSEHDIMKGKLYIENLEKR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Lactococcus lactis subsp. lactis (strain IL1403)
Length
423 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.574 kDa
Sequence
MTPAQRKFLKIVKDEHYFDKDSKILLALSGGKDSMTLFNWLYDLKEVLGIELGLAHINHGLREESKFEEIALREMATKLKVPIYVDKFTGEFTEKNARDFRYQFFEKLMIGENYNILLTAHHQGDLVETVLMRQITGRPLRSLQGIADRQPFAGGQLIRPLLKFTKEELDAQTYYEDSTNQGLDYFRNRIRNQLIPELKKENPQFSQSISDLSSEIKKALAVINQKISELEIVDEKISSKKFISQTKELQHFILQAFFAQYPEIEVSKKKFAELLHIINRPQQYFAKLNKEFYFVKTKDFFYLEKIQLERENSVEIVSENPQDESFMEVYLPLEGEIEIRKRQPGDQILINGHHKKLRKFFIDNKVPLKARENPLIFVDKKLYAIVGLACSDLSKMLKNDKIRRILWVKPSIGEEINDARKKS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Length
423 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
50.414 kDa
Sequence
MTYEKVLKYVQEKKFFETHYNILIAVSGGVDSMNLLHFLHIYQKKLQIRIAVAHVNHKQRPQADEEEIYLKNWARDNHIPFYTAVFKGIFSEKKARDFRYTFFKNIMKEHGYTALVTAHHANDQAETVFLRLLRGSRLRYLTGIKEIQEFGNGQLIRPFLKFHKKELPNIFHFDDDSNQGDSYLRNRIRNHYLPILTQENPKLSQHLIQMSEETNLLFKAFSDLTSQLDIQDCQIFRSQSEAIQYFLLQNYLRKFPNLEVSKAQFDNLLHILRTKDYYYDYLKNNYYLKKDKKRFKICKIGPETDRFEGEKVLEYGSMVKYGQYIFSFQEGSDSKKGIPVKNDFPIIIRRRKPGDKIKLGSHSKKLRRLFIDEKIPIFKRSNAIIVEQDSDIILILLDGVTYLRKGFKDDIMKGRLYIQNRNW
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Length
423 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
49.218 kDa
Sequence
MAKKDAYKLTYNTSDTLFATNLGDILAPSFASIKQTRNLLGFSSGVDSTALFFLLLECEIPFDIAIVHYHTRLQADDEVAYAKELAATYNKLCFVAHAPHFNANFESNARSFRFDFFQSLIIKHHYTHLLLAHQLNDRLEWLLMQLTKGAGLGNLLGFADERYNYDKSLNNYTIVRPLESIPKNELYRFCKERGIKYFEDSSNQDKTFRRNYFRYEFCDKLVNEFSAGIARSLSYLQRDRQSLENMLYADTLELESLKMQILRQIHNISVPMHTHKICCIIFSIHKSKVQDDENLLLLFCDKVAKQCGYVLSAAQRDEISKSRFNCKIAHFIITSNTHRIYIAQDSMSMYKIVTQSPMSKKFKIFCASHRVPSKLRFLLWAEFCAWEMLCKSAYADADYLVNEQGNQHLFTHFLAKIDNFFTL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Aromatoleum aromaticum (strain EbN1)
Length
423 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.557 kDa
Sequence
MLVAAAVAPRQRLCVAFSGGADSTTLLHLLARLRPRFGFDLCAAHVHHALSPNADAWLDFCARQCAALDVAFHPFREQVARDHPAGLEAAAREVRHAALSRVTCDWLVFGHHQDDQAETLLFRLLRGAGVRGAAAMAAIEPGFPGRLRPLLGVRRADIRAFAQAASLEWIEDESNADPRHARNFLRHHVFPLFGEAFPGAVPALARASGHFREADGLLGDLAALDYAACGGSPWLRDRLLMLSDERVRNLLRWRIRQMGCEAPARARLVEAVRQLRATHAPLYLPLGTAACCTYRDRLWLEPQRDGAPEQPLPWRQEPALCWGAGVVRFEPVTGAGIGRGALQRAMDVALVPRWPGLMLRQDSGRPLRSFKNLCQEAGIPAWLRPRLPVLRVDGEAAWIGEIGVAAEFRCGPGEAGLLLVWQR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus thermophilus (strain CNRZ 1066)
Length
421 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.976 kDa
Sequence
MTEKLLQMMQEKGYFNQHKKVLVAVSGGADSMSLLHFLYNHQKDLDIQLGIAHVNHKQRQESEYEENYLRHWAKEHKVPFHYSAFSGKFSENAARTFRYDFFKRIMKEADYSALVTAHHADDQAETIFMRLLRGSRLRHLSGICDVRSFGTGQIIRPFLHIPKDQLPVTFHFEDRSNSSLAYLRNRIRLTYLPTLSQENPKFKEHLCLLADEIALMDKALEELTKDITITDLSVFQQQTDAVQHLLIQSYLESFPDLQLSKGQFNQLMSFLRKKTSGKMPLKNGYVLVKTQTDFLITKEEPISLSSPSLLEFGKSIVFEEYLLTFSEPHVVSNVDTINIWSDAPIVIRHRHEGDRIDLGTHHKKIRRLFIDNKISEKDRQKAIIGEQDGQIIFLYVAGRLYLKKRPKNAILYGTVVIYKKF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Length
421 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.976 kDa
Sequence
MTEKLLQMMQEKGYFNQHKKVLVAVSGGADSMSLLHFLYNHQKDLDIQLGIAHVNHKQRQESEYEENYLRHWAKEHKVPFHYSAFSGKFSENAARTFRYDFFKRIMKEADYSALVTAHHADDQAETIFMRLLRGSRLRHLSGICDVRSFGTGQIIRPFLHIPKDQLPVTFHFEDRSNSSLAYLRNRIRLTYLPTLSQENPKFKEHLCLLADEIALMDKALEELTKDITITDLSVFQQQTDAVQHLLIQSYLESFPDLQLSKGQFNQLMSFLRKKTSGKMPLKNGYVLVKTQTDFLITKEEPISLSSPSLLEFGKSIVFEEYLLTFSEPHVVSNVDTINIWSDAPIVIRHRHEGDRIDLGTHHKKIRRLFIDNKISEKDRQKAIIGEQDGQIIFLYVAGRLYLKKRPKNAILYGTVVIYKKF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Hydrogenovibrio crunogenus (strain XCL-2)
Length
420 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.521 kDa
Sequence
MSYQKVELAISKLIHLYPSPVQFLVAFSGGLDSTVMLDALCKHVSPQSIHAVYINHGLQPESNQWADACKKACERLGVKFESVDVQVSDISRQGIEAVARQKRYEALYSRVTKGTILLTAHHQRDQAETLLLNMARGAGISGLSGMPYVKNIQLNEQTLQHCRPLLNVDYDAIQSYAKQYRLDWVEDSSNQELDYRRNYLRHEVLPKIRHAWPFSDANFAKSAHHLNESLALLNELAEIDLQHTDYTDFYLSFTNVKELRWSRLKNMTRYWTESYVSGLRLNAKIYQWLQECLNNKNPQAKPKMLLARGELRFYNHVLYYFDDLKVHYCLAFDEFDASALQLFKALDFSEQLSSKQGGKLEGTVVRPLNPNDLSSGSQKKALKKWFKESKVPEWDRQRWPVLEKEGQVVAILGFYTKKSF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Zygnema circumcarinatum
Length
420 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.945 kDa
Sequence
MLTNPIFYLTNSNTSKASTHSNTNSKSLFNTKREDLQILYKLNQLLIEKSILHPYQRILIAVSGGQDSICLLNILNKLRSTWHWKLGIVHCDHKWYLDSALQAIHVSRLAANMQIDLYQALTTQSVNNEQLARNWRYELIRHVAICHNFSVIVTGHTASDRVETLIYNLIRGSGISGLQSISWKRKLNSMLTIRMRSVEEQIILYSKHVKCYQNRENLLEDKKNVDIYLIRPLLNVSRMELKHLVQNWKLSIWSDCSNQNISICRNRIRHQLLPYLRQYFHPKIDYVLNSCTEVMYTETLYLDSIARYVLSKALSFISMPLNDQTCVKLDFELLRAVPLAIQRRILKYFLDVITHTSVSFKHVEQVRIACLITTNSSNQFAKDSMNFTDQLLINRSIYLPGKKILQVINARFLIICNNIT
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Actinobacillus pleuropneumoniae serotype 5b (strain L20)
Length
419 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.577 kDa
Sequence
MLLDTLQTQFRHYFPTQRNFVLGLSGGIDSIVLLHLLAELQLNLRAVHIHHGLSPNADNWAAFCEQVCKRLKIPFILQKVTVDRSEGIEAGARAARYQAIGEIIQPNEVLVTAHHLDDQTETFLLALKRGSGIKGLSAMQAVGFWQNFTIFRPLLNVSKAQIEQYALQQQFTWIEDESNHDSHYDRNFLRNEVLPIVNQRWQHFSQMVARSAQHCAEQQMLLEELLAQELQRYADFSEKRLNIEAFPQFSLAKQQQLIRLWLEKCGAQMPSTAQLMQIIQQTIYADVDKNPQLKLADFWLRRYQHHLYLTGELLEPDDFCQPLFAQQSLTLPDGIGELQHLGDSIIYQKSGKIDRLLLPKALVNAPLQVKLTHQGKVKQYGKPMREEMKKRYQQAQVPVWLRKRTPLIFFHDQLVFICH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Length
419 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.619 kDa
Sequence
MLLDTLQTQFRHYFPTQRNFVLGLSGGIDSIVLLHLLAELQLNLRAVHIHHGLSPNADNWAAFCEQVCKRLKIPFILQKVTVDRSEGIEAGARAARYQAIGEIIQPNEVLVTAHHLDDQTETFLLALKRGSGIKGLSAMQAVGFWQNFTIFRPLLNVSKAQIEQYALQQQFTWIEDESNHDSHYDRNFLRNEVLPIVNQRWQHFSQMVARSAQHCAEQQMLLEELLAQELQRYADFSEKRLNIEAFPQFSLAKQQQLIRLWLEKCGAQMPSTAQLMQIIQQTIYADVDKNPQLKLADFWLRRYQHHLYLTGELLEPDDFCQPLFAQQSLTLPDGIGELQHLGDSIIYQKSGKIDRLLLPKVLVNAPLQVKLTHQGKVKQYAKPMREEMKKRYQQAQVPVWLRKRTPLIFFHDQLVFICH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
Length
419 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
45.435 kDa
Sequence
MLLTIGAQDLVNHLRAQFSAQPPRRLGVAVSGGGDSVALMHLLARCFPRGEVKLCVATVDHGLRSESASEAALVARQAAGLGLPHETLLWTGWTGEGNLQDQARRARYGLLTDWALRNRVTTVALAHTADDQAETLLMRLGRSAGVSGLAAMAPRRMQDGVVLVRPLLGITRDALRDFLRAEGIAWAEDPSNEDIRYDRIKARQALAGLAPMGIDAQRLAEVAANMARAREALDWYTFLAARDLTRIDGGDVLLEPRGFRTLPDEIARRLLLHIVGWIGGGEYPPRRVAVAEALSALRHERSSQLGGCLILGQGRRIRFCREWKAVETLTVPQGALWDGRWVLRGPVVKDGELRALGAAGLKLCPDWRQTGRPYAALIASPSVWSGADLVAAPLAGLANGWTAELESGEEDFYASLLSH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Actinobacillus pleuropneumoniae serotype 3 (strain JL03)
Length
419 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.619 kDa
Sequence
MLLDTLQTQFRHYFPTQRNFVLGLSGGIDSIVLLHLLAELQLNLRAVHIHHGLSPNADNWAAFCEQVCKRLKIPFILQKVTVDRSEGIEAGARAARYQAIGEIIQPNEVLVTAHHLDDQTETFLLALKRGSGIKGLSAMQAVGFWQNFTIFRPLLNVSKAQIEQYALQQQFTWIEDESNHDSHYDRNFLRNEVLPIVNQRWQHFSQMVARSAQHCAEQQMLLEELLAQELQRYADFSEKRLNIEAFPQFSLAKQQQLIRLWLEKCGAQMPSTAQLMQIIQQTIYADVDKNPQLKLADFWLRRYQHHLYLTGELLEPDDFCQPLFAQQSLTLPDGIGELQHLGDSIIYQKSGKIDRLLLPKVLVNAPLQVKLTHQGKVKQYAKPMREEMKKRYQQAQVPVWLRKRTPLIFFHDQLVFICH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Tropheryma whipplei (strain Twist)
Length
415 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.695 kDa
Sequence
MLHRPRITPAVANARRAMLNTLPADLHNQLVLIALSGGRDSLAAMVIASWVIPRLNGRVGAVVVDHGLQENSARIADEVRIRAEQFALNPILIKRVSPSRVSAGPEASARIARYAAFYDALEETKAYAIILAHTLDDQAETVLLGLMRGSGPSSLRGMKAVSYTPEDCRYMNNKACNSVTAVYAHNTQRCSCDSTQRCSCDSRPYPPPPEPRNENRSYFPHPSCKCVEGSATRFTNADIDSRFGVFIRPFLDITRHETGKICEFYGLDYWNDPHNEDVRFSRVRIRHNVMPVLENEIGPGVKYALSRTAKLAQLDTEYLDHLSNELLDEIASKESDWSIRLPINTLQKTPVPIRLRVIRLAALQYFTVSLSFKHTRQIERLLCSSCDIKHVNLPRLITAQRVGNYIYMHTLRGKL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)
Length
414 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.365 kDa
Sequence
MEFEIHLPKEPLLVAVSGGCDSMVLAHLLYEANHDLMIVHVHHGLRKESDEEAEAVRAWAEARRVGIRMTRLEWEGQAPSQAACRTRRYAFFQEVMAETGRRHLVLAHHRDDQLETLLIQLIRGEAGVDGIPRIRSFATGQIHRPLLPYSKQQLYDYAKARQVVWHEDETNAGTKYLRNQMRHRLLPLLAELRPGYEEATVQAAMVRYEQKQEHLKYVTSYVKEQMTDRGLPLEAIQKLPTDFRRLVLRALLPDHDFTSEDYNRFLTLLRVDMPSGEVYYGNWRIQRTYGYVTCVRCPEKNLLPEALEVGIDLGTYHYGEQTITFSRTTTGIPFSAVQFPLTIRSVLPGDRIRLAVGTKKVSRILVDAKVPRASRAEIPVVVDAAGQVLAVIGHRIAIFGSFELLAESCLMIEW
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
414 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.834 kDa
Sequence
MLEEGEHVLVAVSGGIDSMTLLYVLRKFSPLLKIKITAAHLDHRIRESSRRDREFVERICRQWNIPVETSEVDVPSLWKDSGKTLEEIAREVRYDFLKRTAKKVGASKIALAHHKNDLLETVVHRLIRGTGPLGLACISPKREEFIRPFLVFKRSEIEEYARKNNVPYVVDETNYNVKYTRNFIRHRIVPLMKELNPTVEDAVYRLVSVTHLLRNFVERTVQDFVERNVYFYKDYAVFVEPEDLFLFLEVTRWVLKEMYGRVPEYEKLIGTLKSKRVELWSGIFVERSFGYVAVGKTVFKKKYRVEVKGDMLEMEGFKIRVVNNRNDMKFWVRNRKEGDRIIVNGRERKLKDVFIEKKVPTFYRDRVPLLVDEEDRVLWVPGIARSDFLPEDVVVELLEYPVGYVKGGTYFEQV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermotoga sp. (strain RQ2)
Length
414 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
48.827 kDa
Sequence
MLEEGEHVLVAVSGGIDSMTLLYVLRKFSPLLKIKITAAHLDHRIRESSRRDREFVERICRQWNIPVETSEVDVPSLWKDSGKTLEEIAREVRYDFLKRTAKKVGASKIALAHHKNDLLETVVHRLIRGTGPLGLACISPKREEFIRPFLVFKRSEIEEYAREKGVPYVVDETNYDVKYTRNFIRHRIVPLMKELNPTVEDAVYRLVSVTHLLRNFVERTVQDFVERNVYFYKDYAVFVEPEDLFLFLEVTRWVLKEMYGRVPEYEKLIGTLKSKRVEFWSGIFVERSFGYVAVGKTVFKKKYRVEVKGDMLEMEGFKIRVVNNRNDMKFWVRNRKEGDRIIVNGRERKLKDVFIEKKVPTFYRDRVPLLVDEEDRVLWVPGIARSDFLPEDVVVELLEYPVGYVKGGTYFEQV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Caulobacter vibrioides (strain ATCC 19089 / CB15)
Length
408 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
43.112 kDa
Sequence
MRLDQVRAALDRRLDPASRAPLAVGFSGGGDSLFLLKTVLDWARPLDRPVLALVVDHQLQPQSTAWTAEAVAKARALGAAALGLTWTDQKPRTGLPAAARRARHALLATAAREAGARVLILGHTASDLAEGVAMRAEGSSVSNPRAWAPSPVWPEGRGLFVLRPLLTLTRAEIRDALTREGETWLDDPANLDLRYARARARAAGALTPLLPVRESPPPGVFEIDPAGAIRLPRDVVPAHLAAALLCASGAERPPRGDRLARLVERLRSGARFTATLAGARIEADQAVLICRDAGEAARGGLARLDLAPGACGVWDGRWEVVAGKTALAVVALRGRTSSLPAEQRARLSAIAPAVRPSLPVLLSLDGDAPGELVLDDLQLEADGEARVRSLVPDRFKAAVGLLDQESVT
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Tropheryma whipplei (strain TW08/27)
Length
407 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
45.844 kDa
Sequence
MLHRPRITPAVANARRAMLNTLPADLHNQLVLIALSGGRDSLAAMVIASWVIPRLNGRVGAVVVDHGLQENSARIADEVRIRAEQFALNPILIKRVSPSRVSAGPEASARIARYAAFYDTLEETKAYAIILAHTLDDQAETVLLGLMRGSGPSSLRGMKAVSYTPEDCRYMNNKACNSVTAVYAHNTQRCSCDSRPYPPPPEPRNENRSYFPHPSCKCVEGSATRFTNADIDSRFGVFIRPFLDITRHETGKICEFYGLDYWNDPHNEDVRFSRVRIRHNVMPVLENEIGPGVKYALSRTAKLAQLDTEYLDHLSNELLDEIASKESDWSIRLPINTLQKTPVPIRLRVIRLAALQYFTVSLSFKHTRQIERLLCSSCDIKHVNLPRLITAQRVGNYIYMHTLRGKL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma mycoides subsp. mycoides SC (strain PG1)
Length
401 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.394 kDa
Sequence
MSLFNINKSKKYLIAVSGGPDSVFLLCNIVKLVDPNDLVVCHVNYNFRSDSNNDQMIVTNLCKQLNLKLEILNINKDYSLLKQNFESWARAQRYDFFNMIASKYQIYNLLVAHNLNDLIETYLLQLQRNNLVDYYGLKPVSHYKDLVVYRPLLDIKKSQILNYLNTNKISYAVDSTNSDIKYQRNKIRATLNENNFTKILDQINKANNNLNSIKKIVDNYLKNNIINNELNLTKELFLLDQTCIQRIIYTYFKLINKENLLLNRSNKTISEIVKRLVNSNKNYWKINLNDHSLIKDYNKLFVIKNSLLEPKTIIINDLNDLINQTTFKNIKEIEQIILKDKNFSYVITTDYEMYKSITTIANKKTNRYFIDRKISYKTRLLSPVVYNIKNKIILNKIKKHY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella philomiragia subsp. philomiragia (strain ATCC 25017)
Length
400 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.261 kDa
Sequence
MSLDKTQIISQILNHSPSHIIIGYSGGVDSSVLLDITKDLDIPTIAIYINHNIHPDALKWQLHCQTICNNANIDFIAHSLDQAPKGESFEAWASKQRMDFFIEIMSQYSSPILLLGHHLDDQAETFLIQAIRGSGLAGLASMPYYKQLNHGAVLRPLLDYTKKDIQDYASQNKINHIYDDSNENIKYRRNLIRNQIMPILEQINPNISRTLSRSAKICAESSNILQKLLNEKLQKISQNNSLIISELLSLDKDIQKSLIHHWFKETTNQSLKNKQTEEIHKALNNDIHTGWQFDINQQFQISVEYNQLIIKNNNQVDLILDNKDIIEWLKERFNKDFDTRELIVRQRQASDKCRYQGRDKANKLKVLFQELKIPTSERSKAKVILLNDKIIAVYPFFICD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Wigglesworthia glossinidia brevipalpis
Length
400 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.672 kDa
Sequence
MLKKFFKEISYKKSYVLAFSGGLDSTVLLHMISLYIKKIKNNNNFFKKIFKFRAVYINHNICKESKYWSNHCHDQCLKYKVFFKSINIFISDFSEGIESSARRERYKALFSDLNPEEVLITAHHQDDQIETILLSLKRGSGPRGISGMQSIKKFDSHIIKRPLLHCKKEDIKLYAIKHNLNWIDDKSNLNIKFDRNFLRSEIIPLLKKRWPNIGNTISRSAKLCFDQEKLLNELLKDTLNSLVEKDKSLKFIELFKMSEIKRFAILRKWFCLNNFKMPSLSQLKHIWKNVIISKKDSKAEIKINNNIIKRFKKNLYFIPIYSKNHLKNIIFKTSLNHSKKIVLPYDLGTLITKPIMINENFIKKINFFYYNNKKKFIFLINLNYMKKMSFTVKLWILFIC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
47.758 kDa
Sequence
MERFKLNTTLSYLVAVSGGPDSMFMLNELIKMNIKEIVVCHVNYNFREDSWKDQKLVEDFCLKNNLKLEKLIINQDYSKLKENFESWARNIRYDFFVEISKKYNIQNVLIAHNRNDLVETFLLQQDRKGYVKHYGLNKTSTYKEITIVRPMLNILKSEILKSLKEENIAFVIDSTNEDKKYKRNKIRANLSESTFNDFEETIKKLNKKLEIINLEVNWYVNNNMSADELKINKNLQDQDLEFIQRTIYKWLEVIKKDFVIQNRRNKTIFEIAKNIKVSEKVFWEINIGEYSIIKDYENLFIIETKAIQPKTILIKSKEDLYLSEEFINWLDLLNAIKRNKENYPYVITNDFLTYKLNTYTFGKKTNRYLIDKKIRYKNRMLKAVVYSTKTKKILNTIK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. tularensis (strain FSC 198)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.023 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.039 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLASIPHYKELHHGGVLRPLLKYSKIDIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. holarctica (strain LVS)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.039 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLASIPHYKELHHGGVLRPLLKYSKIDIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. mediasiatica (strain FSC147)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.022 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKKDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. novicida (strain U112)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.067 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQRYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQPYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEEFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNIGQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKSLLHLWFKQNTQQSLKSKQIKELHLAINNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDMSKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. holarctica (strain OSU18)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.039 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLASIPHYKELHHGGVLRPLLKYSKIDIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.023 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Francisella tularensis subsp. tularensis (strain WY96-3418)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
46.023 kDa
Sequence
MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Gluconobacter oxydans (strain 621H)
Length
398 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
43.874 kDa
Sequence
MARFGPWPPDIDDAPVGLAVSGGADSMALAFLARRWRRNVVAFVVDHALRPESAAEAQLTVHRLAGMNVKARLLTLAPFPKGRMQERARHARFEALEAACVSEGCLDLLVAHHAGDQDETVWMRHLHASGPLGLSGIQPVSVRGRIRLVRPLLTFPTARLRLTLQAENLPWIEDPSNANRRFERVRLRQDLTPEQRQEARVLQQDALQERLRLEAELAEELGRHAVWYSQGWVFLGQEGVDEEALSVLIRLVSGSAYRPAREAVRTLMTQGYGTLSGVQVRPAGRFGNGIILVREERALGPFVPAKAGAVWDGRWRLLACDVPQGSLIGSLGDAIHVMDLRRLGVPYAAARCLPGVWHEGRLVLGPRLGERAWGEFAGEADFVWSSGVPATGENHFGT
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Length
397 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
44.519 kDa
Sequence
MIGDVLPTTPNESPNWHRLRRAIRSTWPNRHGRSSDVATLVGCSGGADSVALICLLAELWAEESNGLNPANETVTKPVAPLVVAHCNHGLRGEESNADEAFVRQICDQLQLPLVIHHVPPLNNSATSGPVSDERTLRQIRRDFFERAAKQHGCRYVAVAHSADDQAETMLHHFIRGTGPLGLAGIAEASELDTDIVVRRPLLQVRRDTLRDGLREIGQPWREDASNRHTIYTRNWIRHDVLPLIESRYPNAVEAIHRAGTLQHEMNEMVRRLAERWLEAFTDFSGDRWTIHTERLSKSATPEKRMDDTNAACSWMIERPVIVAASQLAWDRLGWSRGSMTMQHWQRLTGLINDQSCWHTSDIDVSTSQAVDGIDHGGHFPGGICLSVEAKQLVLRSE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bifidobacterium longum (strain DJO10A)
Length
388 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
41.156 kDa
Sequence
MAYSARLRKAVGAVRTTLSAVELCDVQAPEFAQHGDHAVASDAPLVLVACSGGRDSMALAAVSHIVCTSMGVRCGVVIVDHGLQEGSEQVAGEAANRCRALGLGPVIVRNATVQARGEGLEAAARQARYNELCAAARESGAIAVLLAHTMDDQAETVLIGLLRSRGVDALAGMPQVFTRSGVTFARPLLTLTRAETTGICEDLGVEYWDDPTNGDAVDGELPNDYPLRSRVRHDLLPAIERFAGFNVTRHFAESARLARMDKEYLDQRSDEVMGEAVTTVDWPASSAAVSTDTPRACAAGDTNDSSHGVGLMISVRRIAREPEAIRLRVIAHALSQAGVNASAAQIAAIDRLVVDWHGQGGVSLPRGYSANRKKHVIRVCQDGAHANR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bifidobacterium longum (strain NCC 2705)
Length
388 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
40.903 kDa
Sequence
MAYSARLRKAVGAVRATLSAVELCDVQAPEFAQHGDHAVAADAPLVLVACSGGRDSMALAAVSHIVCTSMGVRCGAVIVDHGLQAGSERVASEAADRCRALGLGPVIMRNATVQARGEGLEAAARQARYDELCAAAHESGAIAVLLAHTMDDQAETVLIGLLRSRGVDALAGMPQVFTRSGATFARPLLTLTRAETTGICEDLGVEYWDDPTNGDAVDGELPNDYPLRSRVRHDLLPAIERFAGFNVTRHFAESARLARMDKEYLDQRSDEVMGEAVAAVDRPASSAAVSTDAPRACVAGDTNDSGHGIGLMIGVKRIAREPEAIRLRVIAHALSQAGVNASAAQIAAIDRLVVDWHGQGGVSLPRGYSANRKKHVIRVCQDGAHANR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Length
388 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
41.052 kDa
Sequence
MAYSARLRKAVGAVRATLSAVELCDVQAPEFAQHGDHAVAADAPLVLVACSGGRDSMALAAVSHIVCTSMGVRCGAVIVDHGLQEGSEQVAGEAANRCRALGLGPVIVRNATVQARGEGLEAAARQARYNELCAAARESGAIAVLLAHTMDDQAETVLIGLLRSRGVDALAGMPQVFTRSGVTFARPLLTLTRAETTGICEDLGVEYWDDPTNGDAVDGELPNDYPLRSRVRHDLLPAIERFAGFNVARHFAESARLARMDKEYLDQRSDEVMGEAVTTVDWPASSAAVSTDTPRACAAGDTNDSSHGVGLMISVRRIAREPEAIRLRVIAHALSQAGVNASAAQIAAIDRLVVDWHGQGGVSLPRGYSANRKKHVIRVCQDGAHANR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bifidobacterium animalis subsp. lactis (strain AD011)
Length
382 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
41.836 kDa
Sequence
MAYSAAMKAAIGEMRDVLKAHGLGQQSKEFSAHGEHKPHDDAPFVFVACSGGRDSLALAACAQVVCAAWGIRCGAIIVDHHLQDASHKVAQQTAQTCRDLGLEPVLIVDVQVKERGQGIEAAAREARYAALVGTARRWHATAVLLAHTKDDQAESILIDLIRAAGTDAFAGMPQTQLFDDVLVLRPLLGITRAQTTRICEDEGLEYWDDPTNGDAVPLETALPASYPLRSRVRHDLMPYLSAFAGCDMVDRLARTARIARRDVEALNQEAERALAQTVEFEGNMRDLQADRLADDKLGANIDARALERWPEAIRYRVIARTLAACGLAYASRHVAAVDKLVSQWHGQGKVALPSKYSAKRKAHVIRICEDITHANRRCAKRN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Nephroselmis olivacea
Length
367 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
42.863 kDa
Sequence
MKGGRVQVITKNNSIAKHQLGEYAVHIYVLLYYLSMREILREFEEACLLQGLVSPSTRLLISCSGGQDSVTLLFLLCQLQTNWTWRLGVVYCNHMWRYGSIETPAKLARICLLFGVSCSFSVSGSRLQKEEEGRSWRLRVLCRMSSIHSWFYISTGHTASDRIETLLSNVLRGSSSSGMRSINWYTSLDTQVGHRRISIPIIRPLLGISRLELRNYANRWKLPLCYDPSNQDQRIRRNRIRHELLPYLRHWWNPQIDRLLAQTAEVTSWESSYYDLICTQICQQYEWIGDGGVRFPWRIFHSIPTSLHSRILWIFLNRALVFLNPAHGFQGNFDILQFLLETKTCHCRHGSIYISKDVDWLRMTLVK
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Hyphomonas neptunium (strain ATCC 15444)
Length
367 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
39.592 kDa
Sequence
MLGLGPQQAAFEAALGALPDRLLDTPVGVAVSGGSDSLALLILAHRWAARRGRVLRALTVDHGLRPESRAEAEAVGRLCADMGIEHDILRLEGAAPRQSALRRGRHAALARTIADKSGHLLLTGHTADDQAETFLMRARQGSGWYGLAGMRPLSLSPVWPEGEGVFIARPLLGIRREALRAFLRDEGLGWADDPSNDNPAFERVRMRRLLCPEMSRNVPVLSLVDRFQTLRMIEDGAIWRWMTANVRAGEAGIHVASFAGHPPERAARALGMLLQIAAGREMPPRGESLRRLAEEIVSKGDFRGATLGGCRITARRTHICLKPECGPLPPGTAARLAATQAILSGNPNEIAASAGKESFLEDLVPIF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Length
361 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.526 kDa
Sequence
MSDDDNSPISAREAKQLFAELKSAPALVLAVSGGPDSIALMWLAARWQRSLARGPRLTVVTVDHGLRAEAAREAREVKRLATELGLPHRTLRWRGAKPKTGLPAAAREARYRLLMQAARSAGASHVLTAHTRDDQAETLLMRLVRGSGLAGLSAMARLTERDGIVLARPLLDVPKAQLIATLKRAKIGFADDPTNRDTAFTRPRLRALLPQLAAEGGDARSLARLAARLARANAAVEVLTDGAERFLRLRDRDDAPHGPDMRSFEAGAFATLPEEVRLRMLLRAINALGHEGPAELGKVETLLAALDQAIAAGMAAAPRAAVNGRPVLKQTLAGALISLAGGRIQIAPAPARRRKGDRGGS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length
358 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.255 kDa
Sequence
MSTGQSEDHLPISAAEAERLFAPFADSGVLTLAVSGGPDSMALMWLAARWRATRAGGPRLLAVTVDHGLRPESRREALMVKQLARQLGLTHRTLRWSGEKPAAGIPEAARIARYRLLARAAEQAGASHVVTAHTRDDQAETVLMRLLRGSGIAGLAAMAPVSRRDGLLLARPLLSLSKARLLATLRSAGIAFADDPTNRDPAFTRPRLRALMPTLAAEGADPRTLATLANRARRANAAIELMADGAERYLALLAAGRSSKRRGGEGEMFDPRAFAALPAEIRLRLLMRAIDRVGTEGPVELGKAEALLERLDRTLAGITDGGTAERGTLKQTLAGALVSLAKDAIRISPAPPRRRRGE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
352 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.722 kDa
Sequence
MGPHPAVAAIRLAVRRVLHDILTELNTPAGVPAATAVERTPERAPGLPTAPLVLVACSGGADSMALASALAFEAPRLGVRAGGVTVDHGLQSGSDLRAEEVVLRLRELGLDPVEATAVTVGRAGGPEAAARDARYAALDAAAARHGAAAVLLGHTRDDQAETVLLGLARGSGIRSLSGMAAVSGAGGRYRRPFLQVDRQTARKACMVQSLPVWDDPHNADPAYTRSRLRHEGLPALEKALGKGVVEALARTAQLSRDDADALDTWARQAEAGVRDATGGLECAKLYALPPAVRRRILRRAALEAGAPGGALFARHIEEVDRLITGWRGQGAINLPGKVVARRQGGRLVIRQG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Length
347 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.41 kDa
Sequence
MERTIKGVCDGENGEGVRNCHCVVALSGGADSTALLLILHYLRQRLGLSLSALHVDHGLRPESAAEARAAVTFCHALGIPLAVHTLTVDELAAVWRVGTEEAGRKARYDLLAAALPSPAADWICTGHHLGDLAEDVLMRLVRGCGWPALGGMRLCDPARRILRPLLLTEKDRLEAFLATLGVSWTEDPSNASDTYLRNRMRHGVIPLLTAENPGFLDQVRDLWQLAHIDADFWETRTAATLSAAPASPSHVEGEASAPHDAAHGAESIRLPKTTLTGLHQAERLRLFKEVLRRMGEGQARAETLLALDAAWVAGRGGTRFMFAGCKTATVRRGDIIFSGGPPAEDTP
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Length
346 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.825 kDa
Sequence
MSGTDHEAVSATEARRLFADWKAAPAIVLAVSGGPDSLALMWLAARWRKALKRGPALAVVTVDHGLRPEAAAEARAVKRLAASLDLPHRTLRWSGDKPSTGIQAAARGARYRLLAKAAKTLGASHVMTAHTRDDQAETVLMRLSRGSGIAGLAAMAREIERDGVVLARPLLDVPKARLIATLAKARIAFATDPSNADPRFTRPRLRELMPQLAAEGCDARSLVRLAVRAARADAALELMTDGAEQFLASLDAGSERPGVNARAFLGLAAEIQIRLLLRTLSRHGHEGPPELGKVEALAEALSQAAARRPQAAAKIRLKQTLAGAVISLTGDRLVIVPAPPRRGRVR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Length
345 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.173 kDa
Sequence
MGPHPAVAAIRLAVRRVLHDILIEHAPGSADLPRDVPHDLPPPPLVLVACSGGADSMALASALAFEAPKLGIRAGGITVDHGLQSGSDLRADEVVGRLVDLGLTPTESIAVTVGRDGGPEAAARDARYAALDAAARRHGACAVLLGHTRDDQAETVLLGLARGSGIRSLSGMAAVSGTGGRYRRPFLQLDRQTARKACMAQSLPVWDDPHNADPAYTRSRLRHEGLPALEKALGKGVVEALARTAQLSRDDADALDVWAGQAEASVRDAAGLLECAKLYALPPAVRRRILRRAAIEAGAPAGSLFARHIEEVDRLITGWRGQGAINLPGKVVAQRQGGRLVIRQG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Methylobacterium sp. (strain 4-46)
Length
344 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
35.175 kDa
Sequence
MSDAARPLDPDEAARRLGPWLGAGGQAGGVVLAVSGGPDSTALMGCAAALPPRVPVLVATVDHGLRPESGEEAAGVAALAGRLGLPHRILTWRGEKPRTRLQEAARAARYDLLLGLAREAGAGAILTAHTLDDQAETVLMRLCAGSGPAGLAGIAPARRLGGLLLGRPFLDLPKARLVATCAAAGWPFAVDPGNAAARFARARLRRVMPLLAAEGLTPARLARLAARLRRNEAALAAAAEAARPSLAAAPAGPGRLALDAAGLAALPEAVALRVLADAIAALRAGERRPERLERLEEALFGRILPAIAAGTPLRLTLGGALLDLAGGRLLLAPEPPRRRTKRAG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermosynechococcus elongatus (strain BP-1)
Length
344 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.878 kDa
Sequence
MWGIHHARLHTTLKTQQWLPLGSRILIALSGGQDSVCLTRLLLDLQPHWQWSLVAVHCDHRWRADSTANANFVQQLAQKWHLPCEVVSAPDLPKTEAAARSWRYQVFESVAKALDCTHVVTAHTQSDRAESLLLHLLRGTSPDGLATLLPSRSLGAIQLVRPLLGMTRAQTAAFCQAYGLPIWQDETNHNLEYRRNRLRLELIPYLQQHFNPNVEEALAQTAELLASDRAYFEAEVERLAPTVLREHPPALDRLRLREFPLALQRRLIQCFLRQHLKRGLNFRVIEAVRALMTTGNGSQTASLPGGQHLRVCGRWIELVRPMPPPPAPVPPDPGERSPPPSPLY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
344 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.766 kDa
Sequence
MSTSTAAPAPSLSDLCPAALRRPVAAALRALDPAPARLAVAVSGGADSAMLAVAAAAALPPGCTLRLFHVHHGLQAAADQWAAQVRGLGALLGVPVDEARVTVPPGQGLGMEAAARLARYQALAGLARQHGVRHILLAHHRNDQAETVLLRLLRGTGLQGMAAMAPLSERDGVAYLRPWLDVDRAAILALAGAVRAQCGWQAVQDPTNTDPRYARAAVRTQLAPALDARWPGWQAIVARHARQMAEAAEIVAEVARADFDTLEPADAGRSFSLAAWRGLSAARQAQALRHWLASQDAPMPTEARLAELQRQLRQLHALGHDRHLRWQHAGRVVRCERGRVWIDD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Length
344 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.794 kDa
Sequence
MSTSTAAPAPSLSDLCPAALRRPVAAALRALDPAPARLAVAVSGGADSAMLAVAAAAVLPPGCTLRLFHVHHGLQAAADQWAAQVRGLGALLGVPVDEARVTVPPGQGLGMEAAARLARYQALAGLARQHGVRHILLAHHRNDQAETVLLRLLRGTGLQGMAAMAPLSERDGVAYLRPWLDVDRAAILALAGAVRAQCGWQAVQDPTNTDPRYARAAVRTQLAPALDARWPGWQAIVARHARQMAEAAEIVAEVARADFDTLEPADAGRSFSLAAWRGLSAARQAQALRHWLASQDAPMPTEARLAELQRQLRQLHALGHDRHLRWQHAGRVVRCERGRVWIDD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Prochlorococcus marinus (strain MIT 9313)
Length
343 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.259 kDa
Sequence
MASSSSTQLPWSAWHARLHHKLLANPDLLPAKASLLIAVSGGQDSMALLGLLIDLQRKHGWSLEVWHGDHNWHKQSATIATELKNWCESHNLSFCSDQAKPGQTNNEATARHWRYEQLTLHAERLSSNNPNHPCRYVLTGHTSSDRAETLLLNLARGTDLAGLSSMRQCRPISKDHPHKNVQLIRPLLGFSREDTALICSELGLPIWLDPANSNPDFSRNRVRQEVLPVLESLHPGCSLRMAALAERLNHHHADQQAIAMLALNNLSKQNGLCRKDLAQLPITARTTLLAYWLKRSGAPSLPAVQLEQISQSIAPGKPPGSLHLAQGWKVQWQRNSVQLEHHD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
342 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
39.191 kDa
Sequence
MVWTQLHAEIHRTIRSRHLFEGNKRLLVAVSGGQDSLCLIKLLLDLQPKWGWELGIAHCDHRWRADSQANADHVKNLAENWGVSFYLETATKPVNSEATAREWRYQALSAIAQAHNYQYIVTGHTASDRAETLLYNLMRGTGADGLQALTWQRPLTENILLVRPLLEITRKQTEQFCQEFQLPIWEDSTNQDLKYARNRIRQELIPYLQANFNPQAELAIAQTAELLQADVEYLERTAQQLKEEAMEWEVGEEFLSSSSPSSLLLRLNRQVLQKAPLALQRRVMRQILQEILADAPNFEHIEKLTALITAPNRSQTDPFPGGAIAQVQGNWIILRNGERRSN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Chaetosphaeridium globosum
Length
341 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
40.51 kDa
Sequence
MNHFNLKLIKRIQNDLIKYNLLKPKKSILIAISGGQDSIVLLKILSILQIQWKWKLSIIYCDHQWNIYSKNQAFHLYKVSFQMGIPFYHGVTIKPLRTEKSARIWRYSVFQRIASISKFNVIVTAHSSTDRVETFLYNLFRGTGVQGLQSLTWKKNIQFEILPNFARSKKSFDLKILSLESKNGIQTYSDYNKLQLIRPLLNITRTELGKFCSNENLPLWPDLTNYNLSIIRNRIRYQTMPYLKIYFNCNLEKILAQIAEILYSENLYFENLSKKIMLKISFEEINSKKLSLSLFKILPLALQRRIIKFFFENHFSKILDFRDIEEIRYYILNLSNNSKFL
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060)
Length
339 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
35.242 kDa
Sequence
MTEAARPLDREEFARRLDRWLGPGAAGGVVLAVSGGPDSTALMGGAARLPPLVPVMVATVDHGLRPEAAAEAEAVARLAGRLGLPHRILAWTGPKPRTRLQEAARAARYRLLLDLAREQGAAALLTAHTLDDQAETVLMRLCAGSGPAGLGGIEPVRHLGGLALVRPFLDLPKARLVATCAAEGWPFVVDPGNADARFARGRLRRVMPHLAAEGLTAARLARLAERLRRNEAALAAAADAALDALARPGARPGGMMLDARGLAVLPEAVALRVLARAIATVVGGNARPARLERLEDVLFGRLLPAIAAGGRLRCTLGGALLHLSGGSLSLSPEPPRRAG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Helicobacter pylori (strain J99 / ATCC 700824)
Length
338 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
40.183 kDa
Sequence
MTARDFKNYLEPLREGKNLLGFSGGLDSTCLFHLLVGENIAFDIALVDYSTQKQRLEIIQHAQKLAQTHHKKCYIHYAPKIARNFEMQARKVRYDFFETLIKEHSYKHLILAHHLNDRLEWFLMQLSKGAGLNTLLSFQAYEKRESYAIVRPLLYTPKDTLKTLAKDQKFFEDDSNSSLKFKRNCFRKHYANALMQHYSKGIIQSFKFLDKEKERLYPLIPVSQMHGITFFKHSHNALFMVDKILKKKGYVLSFLQKEEIKHHFFSLEIAQKFIIEKDKEHVFIAFKPQKTLSMPKDFKDRARRLDIPKRLRPVLYAEFLKQPTHDFLTRFKQSLMDL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Synechococcus sp. (strain WH8102)
Length
337 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.383 kDa
Sequence
MGEQRPLALAWSPWHDRLHRRLHQHPQLLPQRQPLLLAVSGGQDSMALLVLLQELQRLHHWPLNIWHGDHGWHSGSAVIAADLRSWCQQRDLPIQVDQAPQGSTASEASARHWRYSQLQQRAEELGADVVTGHTASDRAETLLLQLARGTDLAGLGALRPVRPLFNDSPDGAQLRRPLLGFSRADTAAVCRDLQVPIWHDPSNQSPAFARNRIRAEVLPVLEQLHPGCSQRMANLAERTSQLRDTQQELSQLALQPLRTSTGLDRRRLGALQPSTRRQLLVIWLAQQGVTALNAALLEQLTDRLALSAAGGSCDLPGGWRLQWQGDNLSLQPPAAGH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Helicobacter pylori (strain ATCC 700392 / 26695)
Length
336 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
39.763 kDa
Sequence
MQDFKTHLEPLKEGKNLLGFSGGLDSTCLFFLLVGENIVFDIALVDYNTQKQRLEIIQHAQKLAKTHHKKCYIHHAPKIAHNFEMQARKIRYDFFETLIKEHSYKHLILAHHLNDRLEWFLMQLSKGAGLNTLLSFQAYEKRESYAIVRPLLYTPKDTLKTLAKDLKFFEDDSNSSLKFKRNCFRKNYANSLMQDYSKGIIQSFKFLDQEKERLYPLTIVSQMHGITFFKYSQNALFMVDKILKQKGYVLSFSQKEEIKRSFFSLEIAQKFIIESDKEHVFIALKPPKTLSMPKDFKDRARRLDIPKRLRPVLYAEFLKQPTHDFLTRFKQSLMDL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Synechococcus sp. (strain JA-3-3Ab)
Length
336 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.641 kDa
Sequence
MARLSPLHLRVQCAIRERQLLRPGQRLLVAFSGGQDSFSLLQILRDLQPRWRWQIFVLHCDHRWSADETACAQFLQGWLQQQGLPHAVETADPIRWDEAGARAWRYQQLDKWARTWSCEAVATGHTASDRAETFLWNLLRGTGAAGLVSLDWQRRLDERDPTSAWLVRPLLGLSRWETEEFCRQYQLPVWPDRSNQDLAHGRNRLRLEVMPYLKQHFNPQLEAALNRAATLLQAEHELVVAQAAQLWLQVYEPALPGLRRDPLRAAPLALQRQVMFQFLSLLLPHHPTFEQVEAGIRLLKAGRRSRSPDYPGGGWLEVRGDCVVWVAASQPASFVP
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Length
336 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.635 kDa
Sequence
MTNSTKVEKPWTKWHERLHKSLKSKSNLLPYGSSLLISVSGGQDSMALLKLILDLQRIYEWKVHVWHGDHGWHNQSRQIAEELEEWCKCQKLSFFCNRTNKQKVSTEEDARNWRYKSLIQQAKTLSKESPSLPCERVLTGHTANDRTETFIMNLARGAHLKGLSSLREDRTLETKIQLIRPILRFSRQETIQICDEMDLPIWIDPSNSNIAYSRNKIRAEIIPVLESLHPQSTIRISNLAERLTSLQKDQHQLAHLALGALLTSTGLSRSKMTKLSKTVRAIILAQWLEDNKAPLLSSKQLEELSQKIGKNKGPGNMDISNHLKIRWNKNSIELIN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)
Length
336 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.969 kDa
Sequence
MSDKNSSQKNWTSWHHLLHKEILGNKTLIPDGANLLIAVSGGQDSMALLNLINDMKTQHNWFVNVWHGDHQWHKKSAKYALELKSYCNKKNISFFFDQANKNNISSEEKARDWRYKKLSERANQLLIENQKEIDIYLLTGHTNTDNAETFLLNLARGSNYAGLSNINKKRLLKHHIFLIRPLLIFSREDTKKFCQLQNIPIWEDPTNCDLTIKRNIVRKEIIPILETMYPGCSKRINSFAEKMSNYKNEQNDLSKLASLYCEDAIGVKRELLNSLCIEARCTILNTFLKKDCTKQLSSKNLTHLASSILVKDRGKIDLPDGFEIVWNKDYINLEKN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salinispora arenicola (strain CNS-205)
Length
333 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.299 kDa
Sequence
MAALAPPVAAIRRAVRRALTTLPDAGPVLVACSGGADSLALAAATAFVAPRLGRPAGLVTVDHGLQEGSARRATAVVDWAHTAGLAPVEAIRVDVSERPGGPEAAAREARYQALTEAAGRLGAAALLTGHTRDDQAETVLLALARGAGPRGLAGMPTRRWLGEALLLRPLLEVSREQTRAACTALGLAPWTDPHNTDPAYARARVRSEVLPALVRALGPGVLDNLARTARLVAADTAALDEQATVALDGVRHPDGGLCVGGLAGLAPAVRGRVLHVWARELGARPGALSHRHVDALEALVTGWRGQGAAYLPGGLRVFRRAGRLTVVDPCPPA
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Length
333 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.972 kDa
Sequence
MAALAPPVAAIRRAIRHALIELPDPGPVLVACSGGADSLALAAATAFVAPRLGRSAGLVTVDHGLQEGSAQRAAAVADWARATGLAPVEVVRVDVSGRPGGPEAAARQARYRALTEVAGGLGAAALLTGHTRDDQAETVLLALARGAGPRGLAGMPARRWLGAALLLRPLLEVSREQTRAACTALGLDPWVDPHNADPAYARARVRAEVLPALVRALGPAVVDNLARTARLVAVDTAALDEQASTALDGVRHPDGGLSVGGLAALVPAVRGRVLHAWARELGARPAALSHRHVGALEALVTGWRGQGAAHLPGGLRVLRRAGRLTAIDPGAQV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Ureaplasma parvum serovar 3 (strain ATCC 700970)
Length
333 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
40.137 kDa
Sequence
MKILIKLWTNLINRISNKKYLAAVSGGPDSMAMLNMYKRNIRVVCHVNYHKRESSDRDQQIVVDFCRKNNLIIEILDVDEKVYERYGHIDNFQTKARLIRYDFFKEIGKKYNIENLYIAHNFDDFLETAYMQRARQSKALFYGIKESNVINGIIVKRPVLFVRKQTLQRYCDENKIKYGIDETNELDIYERNRVRKIISSWSLNEVYDFKKFVIKYNKEHSSFANFIDLSYIEFKKNKYKYDYFIRQDDMVQYYLIYYFLIDHKIINPSENKIISLIKFFGKQINKEKAYRVQENIYMHVNDDELISLISYNKSDNISNSNVDIIDDHNVIEK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Length
332 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.996 kDa
Sequence
MRAALAAAAALPVPDAEGDHGPARPHPLAPGALVLIGLSGGADSLALAAAAAFEAPRAGFRSGAIVVDHGLQPGSAEVAAGAACQARALGLGPVLVERVRVEAAGGPEGAARAARHTAFDSAARATAAARILLAHTLDDQAETVLLGLARGSGPSSLQGMLPDTGRLLRPFLGLRRATTRAFCADSGLEPWDDPHNDDPAYTRVRVRSAVLPVLEQELGPGVAEALARTAEQLREDDQALDSLALEGAQELVSQADDGSVALEVRGLAAGPPALRQRIIRLVVSAEFGVSLSRSHTLAVAALIADWHGQGPLSLPGVRVVRQNGLLTFHPHT
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
331 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.135 kDa
Sequence
MNKTEKKFLENMHRQKLVANGDAVLLAVSGGPDSMALLHLFASVASVLHCRLGVAHCNFMLRGDASDADESFVRDACAELGIDFHVRRFDTASVSSAWKKSIEETARLLRYDFFGELCREASYTRIATGHHSDDNAETVLFNLFRGAGISGLRGIRVRHGAIIRPLLPFTRREIVAYLEEKRVVWRDDHTNEGIEYDRNFIRNRVIPVIEERFAHKLMPSLQRISEHAGELEEFIDLHISRLLEAHPGLDLAGGKLHVGTMRQLSMFERKEILKRALKLQGLSVGSNVLNRIAGLLDNQAGRSVPAGAGVEVVLHDGFLRFRQTGNPSDHR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Chara vulgaris
Length
330 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
39.517 kDa
Sequence
MYNFINLIDRIDHILVERKLLLSKQKILIAVSGGQDSIFLLNLLLQLRFHWEWEIGIVNCDHMWNQFSQTASLYVSQLACQMNLNYYQCISPSFYRKEEKARSWRYKLFQRIAYLHDYTIIITAHTASDRVETLFYNLFKGSGLHGLHSLTWKRQIYKKRIHLVRPLLSTTRGELSQIFKQIQIPLYLDSTNLNVKIYRNRIRYQLLPYLRLFFNRNLDRSIAQFAEILHSESLFLETLTQILRNKIEIINKNQKILDIQFIRVIPFAIQRRIIKQFLEHQSIYSFDFCHIEKIRIISNIIIYKSDIYLPGGNRLTISKKYILLCSKISF
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
330 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.771 kDa
Sequence
MAWTLLHSKLHQNLQRRFPELQGTRILVAVSGGQDSLCLLHLLNDLTKQWQWHLAVAHCDHRWPTDAGIADHVQGLAQGYKLPYFQRDAQDLPQTEAAARHWRYHALTAIAKAENFPVVMTGHTQSDRAETLLFNLVRGSGSDGLQAMNWVRNLEESGSDKSPIRLIRPLLEISRQETGDFCQQQQLSVWEDVLNEKLTYRRNRIRGELIPYLKKHFNPQVEKSLAQTVELLTAEVAYLEQVSGEIYQTLSQTDQKSLNCRLLSQKPLALQRRIIRQFLQSCQSQSPNFEEIEQIVGLINAPNRSQTSSLPGQGIVRVEGDFLRYIYQGK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
Length
330 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.564 kDa
Sequence
MSGPHPSVAAARNAVRALLAELEPARGVLVACSGGADSLALAAATAFVAPRAGRAAGAVVVDHALQAGSAEVAARAADQCRGLGLEARVVRVDVDIALGGPEGAARAARYAALEAASREAGDAVVLLGHTLDDQAETVLLRLARGSGARSLAGMPRRRGVFARPFLHLERARLREVVDAVGLTPWEDPTNAVDGPARRADGGPLPRSAIRGRVLPALTEALGPGVPASLARSADLLREDADALDAFAADLLSTARGEDGSLDVEILAAAPPAVRRRALRRAALDAGSPAGDLAHVHVEALDALVTGYHGQAGVDLPGGRRAVRACGRLTL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Length
329 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.295 kDa
Sequence
MKGELRSLLLPELRLFNEAIKGILSSPLSGKLGIAVSGGSDSLALLLLGAVSDFPVEAVTVDHGMRPEAAEEARFVAQICQQIGVPHQILTTKIEANGEGMQAAARIRRYALMAEWAKEKNVGALMTAHHADDQAETFLMRAARGSGLNGLAAIRPDVVITAEGQKLRLLRPLLGFTRSALAEIVEKAGFTFVSDPSNDNPHYDRTHFRRLLKASPWINRQHIAEAARYCQQSEEAIEWITAKEAAARIRKKGEVLYLDPTELPIEILRRLVLRAMETITGNTALRGSALSRFIRSLQQGKKVMLADVIGQGGEYWRFYRAPPRKKAVL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Pyropia yezoensis
Length
329 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.445 kDa
Sequence
MFQNSFLHKKFISTIEKNNLLPYNSSLLVSFSGGQDSLALVKILYDFKNIYNWKISLIHFDHRWRSDSMLVSKQVIKYAKMCNLSVYYFECPKYLNTEETSRKWRYLTLINTAYVNNFNTIVLAHTATDKAETMLSNLFRGTSLDGLSSIHWSSQLSNAVHLVRPLLNCYRSETSWFCRKYFLPVWIDQSNYNNSLSRNRLRQELIPYIKSYFQPQIEQKCYLLSSLISLDVDFLEQEALRIYSLIQHEELLAMNYLVIKLLHPSLQSRILKIFFISNLDLNLNSIQISDIILLINQSISTNINISNYILGTDGTWLYVGAKTKCIKSN
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Polaromonas naphthalenivorans (strain CJ2)
Length
328 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.69 kDa
Sequence
MAAPVASLNPALAGIDSLFSAFPSSSSLPLGVAYSGGADSTALLLAAAERWPGQVQAFHIHHGLQAAADDFVRVCESVCAKAGLPLHIVQVDARHASGESPEDAARRARYAALATAATARGMQGVLLGQHADDQVETMLLALSRGAGLPGLSAMPASFGRGGMVFYRPLLHIPSAVLREWLVEQPIEFVDDPTNTDERYTRNRIRARLLPALAQAFPQFHATFARSARHAAQAQAVLVEVAAQDLAVVGNPPAIKALQALSPPRQANVLRHWLLLQYATPSAAQLEQLLHQVAACTTRGHRIHLKVASGHVTRLGGSLCYSDAAARAC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Synechococcus sp. (strain JA-2-3B'a(2-13))
Length
327 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.675 kDa
Sequence
MARLSPLHLRVQCAIRQQQLLHPGQRLLVAFSGGQDSFCLLQILRDLQPRWGWQIFVLHCDHRWSADETECARFLQGWLQQQGLPHAVETADPIRRDEAGARAWRYQQLEKWARTWDCSAVVMGHTASDRAETFLWNLLRGTGAAGLSSLDWQRHLDDRDPTSAQVVRPLLGLYRWETEQFCQQHQLPVWPDRSNQDLAHGRNRLRLEVMPYLKQHFNPQLEAALNRAATLLQAEHELVVAQAAQLWPQVYEPALPGLRRDPLRAAPLALQRQVMFQFLSLVLPHHPTFEQVEAGIQLLKADRGSRSPDYPGGHWLEVKGDHLVCFH
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Porphyra purpurea
Length
327 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
39.154 kDa
Sequence
MFLDSFLHKKFFSTIEKKSLLPSKSSLLVAFSGGQDSLTLVKLLYDLNPFYRWRITLIHFDHRWRWDSMLASKQVFSFARYYNFPLYYFECPDYLNTEEASRKWRYTTLIDLAVKNNFTKILLAHTATDSSETLLSNLFRGTSLDGLASIGWSCQLAQSVYIVRPLLNFYRFETSWFCRKYYLPIWVDRSNYDYIMFRNRLRQELVPYIKSYFQPNLEERCYSLSSLVKYDTDFLEQEALRIYFILIHQDLIAINHTALRLLHLSVQSRIFKIFFIANLNFNPNSRQIEDVIIFIKQNILSQINMNNYILVMDDIWFYVGVKIIKFS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Length
326 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.758 kDa
Sequence
MGEGGESLSGAASRFRADWQALDPSGRVCLAVSGGPDSLALMLLMQEVAPRDFCVATVDHGLRAESAAEAAMVAGLCEMRGIAYHTLRLDLAGGSAVQERARKARYAALADLARRDGLSAVVTAHHADDQAETLVMRLNRGAGLRGLAGMRAASSVPGAGEVRLLRPLLGWRRAELVALVEDAGLAPVLDPSNHDHRYERVRIRDVMASTKALLPSGFAASASHLAEADAALEWAVERLWLDIGMSAEGSTWNPPEDLPRVLALRLLERVVMHLGGTVPRGPDLVRWLATLRAGGVATLAGVKGDARSGAWRFSRAPEHRSDRRPD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Length
326 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.155 kDa
Sequence
MGKIIQLQEEERLRQGKNLLGFSGGVDSTALFFLLLEREIPFDIALVNYHQRAQAKEEESYAKELAHRHQKRCFTLSCPLGPSNFEHQARLERYRFFESLIHQEGYARLLLAHHLGDRLEWLLMRLAQGSSLSTLLGFSSREIRLGYELIRPLGEITKEALYDYLHQHQIRYFEDESNRDPKPLRNRFRPLSETLLKEHAQGLLQSFRFLQEEREILYGEDPRIRRDSLFYFPSQERETQNLHLIDLSLKALGYVMSQGERQELLKSGFCVVLKGKVAIGRSERGIFIAPFERVIIPKAQRERLRIAKIPPKVRPYCFMAGIDSLL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Prochlorococcus marinus (strain NATL1A)
Length
326 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.782 kDa
Sequence
MRLHKRLKQNKSLLPSNSTILLAISGGQDSMALLKLIIDLKRLHKWQVEIWHGNHQWHSKSEKTEEELKLWCLKNQISFHSNKADKKEVANEEKARDWRYKNLIMKAKFLSSKNIHFPCTRILTGHTATDRAETVIMNLARGTDLTGLTTLKEQRTIESNIDLTRPLLIFNRNETLEICKDFNLPIWIDPSNENINLTRNKIRKEILPILNSIYKGADSRIASVANRLESYNEDQKLFAKIAIQFCQGEKINSLSRIKLFGLTNSIRQIILSNWLKTMGVKRITALQIEEINTKVSQRKPPGSIHLHGDFLIRWNKEAIYISNKTN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Prochlorococcus marinus (strain NATL2A)
Length
326 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.752 kDa
Sequence
MRLHKRLKQNKSLLPSNSTILLAISGGQDSMALLKLIIDLKRLHQWQVEVWHGNHQWHAKSEETEDELKLWCLKNQISFHSNKADKKEVANEEKARDWRYKNLIMKAKFLSSKNIHFPCTRILTGHTATDRAETVIMNLARGTDLTGLTTLKEQRTIENNIDLTRPLLIFNRNETLEICKDFNLPIWIDPSNENINLTRNKIRKEILPILNSIYKGADSRIASVANRLESYNEDQKLFAKIAIQFCQGEKINSLSRIKLFGLTNSIRQIILSNWLKTMGVKRVTALQIEEINTKVSQRKPPGSIHLHGDFLIRWNKEAIYISNKTN
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Length
325 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.033 kDa
Sequence
MTRWWAAVSDLSLRRRLRPALGLLPPGSGLLVAVSGGQDSLCLLKLLVDLAPERGLHLHVGHLDHRWRPGSERDAQRVAVLCNVWGVPFHLEIARTPPASEAAARAWRYCWLEQIARGLALERVVTGHTLSDRAETVLFNLLRGSGGAGLGSLDWERPLGGGVRLVRPLLGITRAETGAYCLAHHLPICIDESNANLTFRRNRIRLELMPYLREHFNPLVEQTLARTGDILHAESELLESLLDEHWHSLVQEGRLHRNTLAALPLALQRRAVRRWLSVGLGRQPNFEHIAAVLGCLSAPNRTRTSPLAHSLLVEVQGEWLGLVGG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
Length
325 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.189 kDa
Sequence
MSSDCWTPFHARLHQLLQRRSLLPTRSRLLLAVSGGQDSLALVQLLRGLQPHWHWSLAIAHCDHGWRSDSTANAEHLRQLADQWQLPFYCQRSPEPPRSEAAARTWRYQVLEAIAADIDAALLVTGHTASDRAETLLYNLTRGSHLQGLASLRWQRSLSDRLTLVRPFLGFTRAETSKMVQQFQLPVWEDSTNRDRRFARNRLRLEVLPQLRQINPQCDRHLANTAELLADEADWLAELTEQVYQQSLSERGLCRSQLAQQPIALQRRVLHAFLQDQLQRSPSTVQVEELRQLITAPQGSCSSSLPQRRVAVVAGDWLRLQSVDD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Length
325 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.603 kDa
Sequence
MLLPETPALLALRQAVRAWTVAFEPRRRVVVALSGGADSLALTAAAVAETDSVDALIVDHRLQPGSDAVARSAADQALALGCRTATVLTVDVAEGGSLEAAAREARYSALRDARTDLPVLLGHTLDDQAETVLLGLSRGSGGRSIQGMAAFDAPWGRPLLGIRRSVTRAACVDLGITPWEDPHNNNPEFTRVRLRHEALPLLEEILGGGVAEALARTATQLREDGEALDEYAEALLLRAVVDGEVEVDTLAEAPTAIRRRALRAWLLQGGAKALTDKQLRAVDALVIDWRGQGGVAIGGGTPEARLVAARRRGRLILGFEDRRRV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rhodococcus jostii (strain RHA1)
Length
325 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.192 kDa
Sequence
MVLPEEPAILEVRHAVRRWIAAHAPDGEIAVALSGGADSLALTAAAAAEARSVCALVVDHRLQPGSADVADEAAARARALGCASAEVLPVDVTGSGGLEAAARQARYRALDSARGTRPVLLGHTLDDQAETVLLGLSRGSGGRSIWGMSAYDTPWGRPLLDVRRALTRQACAELGLSPHEDPHNASPDFVRVRLRTEVLPLLEDVLGGGVAGALARTGEHLREEGAVLDAMAADAQAKAVVEGEIDTALLALSAPPVRRRVLRSWLLAAGARGLGDTQLRAVDDLVARWRGQGQVAIGGGTPDARFVVRRRRGRLNVGLDDRRRV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Rhodococcus opacus (strain B4)
Length
325 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.034 kDa
Sequence
MLLPEEPAILEVRHAVRHWIAAHAPDGDVAVALSGGADSLALTAAAAVEARSAVALVVDHRLQRGSADVADGAAARARTLGCASAEVLPVDVTGSGGLEAAARQARYEALDAGRGTRPVLLGHTLDDQAETVLLGLSRGSGGRSIWGMSPYDSPWGRPLLGVRRAVTRQACTELGLDPHEDPHNSSPDFVRVRLRTEVLPLLEDVLGGGVAGALARTGEHLREEGAVLDAVAADAEAKVVVDGEIDAALLALSAPPVRRRVLRSWLLAAGARGLGDTQLRAVDDLVARWRGQGQVAVGGGTPDARLVVRRRRGRLNVGLDDRRRV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Thermobifida fusca (strain YX)
Length
324 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.04 kDa
Sequence
MSGPPPPVALVRTAVRRALRDLPAGSLVLVACSGGPDSLALAGATAFVAPRLGLRAGGVTVDHGLQEGSAERADTVAALLRNLGFDPVERVSVTVGTAGGPEAAARSARYAALEKTADVHQAAAVLLGHTRDDQAETVLLRLARGSGARSLAAMATRTGRYLRPFLDVDRRTVHEAASLMGFEPWSDPHNTDPAYTRSRVRHEALPVLERVLGPGITEALARTATLLRDDADALDAWADQAQQQVGRGPTALDAAGLAGLPRAIRTRLLRRIALAAGCPAGALTAEHVFALDRLVTEWRGQSHVDLPGARRGRRHDGQIIVSAD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
323 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.13 kDa
Sequence
MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAARLWPTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVGAAGGREAAARSARYSALEEHRDGPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTEVLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRGQELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVTAWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
323 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.13 kDa
Sequence
MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAARLWPTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVGAAGGREAAARSARYSALEEHRDGPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTEVLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRGQELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVTAWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycobacterium leprae (strain TN)
Length
323 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.113 kDa
Sequence
MDRQGAVGQLRRTVEEFAGTYCDIDDQWCVALSGGSDSLALTAVAAQLRSTTAFIVDHGLQSDSAAVAETARKQAISLGCVDAQVLCVQIDPPFGPKGGLEAAARAARYAVLGANRNGPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPHDPPWCRPLLGVRRSVPRAACHELGLNAWQDPHNTDCRYTRTRLRLEVLPLLEDVLGGGVVEALARTATALREDTELIDTFAAQALPNICAGSGLHARALAALPDAVRRRVIRGWLLNGGATGLTDKQIRGVDTLVTAWRGQGGVAVGSTLRGQRLIASRYDGVLTLHCAPV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
323 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.13 kDa
Sequence
MDRQSAVAQLRAAAEQFARVHLDACDRWSVGLSGGPDSLALTAVAARLWPTTALIVDHGLQPGSATVAETARIQAISLGCVDARVLCVQVGAAGGREAAARSARYSALEEHRDGPVLLAHTLDDQAETVLLGLGRGSGARSIAGMRPYDPPWCRPLLGVRRSVTHAACRELGLTAWQDPHNTDRRFTRTRLRTEVLPLLEDVLGGGVAEALARTATALREDTDLIDTIAAQALPGAAVAGSRGQELSTSALTALPDAVRRRVIRGWLLAGGATGLTDRQIRGVDRLVTAWRGQGGVAVGSTLRGQRLVAGRRDGVLVLRREPV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.014 kDa
Sequence
MQIKDEILSLLKRGKNLLAFSYGSDSSVLFYLLMQEKIDFDLVMINYKTRKNSDLEELKAKELALKFHKKIFIKHAPKFQSNFEKKARDFRYDFFEKICLEQGYDHLILAHHLNDQFEWFLMQLSRGAGLAEILGMQECEKRSNYTLLRPLLFISKDEISSFLKEKDIFYFHDESNENEKYFRNYIRKNFSNAFVSEFHQGLKRSFSYLDEDRKKLYDFENIKEIQGLLICPKNESLIARAVKMKGLLLSTAQRKELLKGDCVLGGKIALAYKNEQAIVFEYETCQKLPKNFKEECRIAKIPRLLRAYLYNHKIDISSLSF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Campylobacter jejuni (strain RM1221)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.041 kDa
Sequence
MQIKDEILALLKKGKNLLAFSYGSDSSALFYLLMQEKIDFDLVMINYKTRKNSDLEELKAKELALKFHKKIFIKHAPKFQSNFEKKARDFRYDFFEKICLEQDYDHLILAHHLNDQFEWFLMQLSRGAGLAEILGMQECEKRQNYTLLRPLLFISKDEISSFLKEKDIFYFHDESNENEKYFRNYIRKNFSNAFVSEFHQGLKRSFSYLDEDRKKLYDFENIKEIQGLLICPKNESLIARAVKMKGLLLSTAQRKELLKGDCVLGGKIALAYKNEQAIVFEYETCQKLPKNFKEECRIAKIPRLLRAYLYNHKIDISSLSF
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia muridarum (strain MoPn / Nigg)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.505 kDa
Sequence
MVIRLFENDKQLEVFFSSLDKKKKYLLALSGGSDSLLLMYLLRSRGISFTAVHVDYGWRETSYQEACDLASLCEREQIPFILDRQEVANPMDFSDIENIARQYRYELFYRLCKERLFAGVFLGHHADDQAETILKRVFEGAHLGNLKGMARYGTYKGITLLRPLLHITKRQIVEALDNYRIEYVQDATNADERFLRARMREQLFPYLQEIFGKNIRQPLLFLAEDSAELREYLDQQAAPFLSQVIDNEIGQFLPVGQELLQTAFLTKWVCKQFFFKQGLVASKGFLQTVYDHLVRRSEARLRLRNRTVLVKARGVIIESIY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.243 kDa
Sequence
MITRLFENDKQLEGFFSSLDKKKKYLLALSGGSDSLFLMYLLKSRAIFFTAVHVDYGWRETSYQEASDLAALCEQEQIPFILDRPEATDPMDSRDIENAARRYRYELFYRLCKEKCFSGVFLGHHADDQAETILKRVFEGAHLGNLKGMSAQVMYRDVALLRPLLHIPKHKIVEALDSHQVQYVQDITNCNERFLRARMRERLFPYLQDVFGKNIRDPLLSLAGDSAELREYLDQQTAPFLLRVVDNERGKLLPIEQELLKTPFLAKWVCKQFFLNEGLVASKSFLQTVYDHLMTGSTARLRLRNRTVLVKARGVIIESIY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.342 kDa
Sequence
MITRLFENDKQLEGFFSSLDKKKKYLLALSGGSDSLFLMYLLKSRAIFFTAVHVDYGWRETSYQEASDLAALCEQEQIPFILDRPEATDPMDSRDIENAARRYRYELFYRLCKEKCFSGVFLGHHADDQAETILKRVFEGAHLGNLKGMSAQVMYRDVALLRPLLHIPKHKIVEALDSHQVQYVQDITNCNERFLRARMRERLFPYLQDVFGKNIRDPLLSLAGDSAELREYLDQQTAPFLLRVVDNERGKLLPIEQELLKTPFLAKWVCKQFFLNERLVASKSFLQTVYDHLMTGSTARLRLRNRTVLVKARGVIIESIY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.243 kDa
Sequence
MITRLFENDKQLEGFFSSLDKKKKYLLALSGGSDSLFLMYLLKSRAIFFTAVHVDYGWRETSYQEASDLAALCEQEQIPFILDRPEATDPMDSRDIENAARRYRYELFYRLCKEKCFSGVFLGHHADDQAETILKRVFEGAHLGNLKGMSAQVMYRDVALLRPLLHIPKHKIVEALDSHQVQYVQDITNCNERFLRARMRERLFPYLQDVFGKNIRDPLLSLAGDSAELREYLDQQTAPFLLRVVDNERGKLLPIEQELLKTPFLAKWVCKQFFLNEGLVASKSFLQTVYDHLMTGSTARLRLRNRTVLVKARGVIIESIY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.332 kDa
Sequence
MITRLFENDKQLEGFFSSLDKKKKYLLALSGGSDSLFLMYLLKSRAIFFTAVHVDYGWRETSYQEASDLAALCEQEQIPFILDRPEATDPMDSRDIENAARRYRYELFYRLCKEKCFSGVFLGHHADDQAETILKRVFEGAHLGNLKGMSAQVMYRDVALLRPLLHIPKHKIVEALDSHQVQYVQDITNCNERFLRARMRERLFPYLQDVFGKNIRDPLLSLAGDSAELREYLDQQTAPFLLRVVDNERGKLLPIEQELLKTSFLAKWVCKQFFLNERLVASKSFLQTVYDHLMTGSTARLRLRNRTVLVKARGVIIESIY
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Length
321 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.445 kDa
Sequence
MAAALRALDPAPARLAVAVSGGADSAMLAVAAAAALPPGCTLRLFHVHHGLQAAADQWAAQVRGLGALLGVPVDEARVTVPPGQGLGMEAAARLARYQALAGLARQHGVRHILLAHHRNDQAETVLLRLLRGTGLQGMAAMAPFSERDGVAYLRPWLDVDHAAILALAGAVRAQCGWQAVQDPTNTDPRYARAAVRTQLAPALDARWPGWQAIVARHARQMAEAAEIVAEVAQADFATLEPADAGRSFSLAAWRGLSAARQAQALRHWLASQDAPMPTEARLAELQRQLRQLHALGHDRHLRWQHAGRVVRCERGRVWIDD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Length
320 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.521 kDa
Sequence
MDRPGALDRLRTAVEAFSTAHLGAVERWCVALSGGPDSLALTAVAARLRPTTAVIVDHGLQPDSAAVAQTARAQAIALGCVAAQVISVHVDGEGGLEAAARRARYAALAAHRDGPVLLGHTLDDQAETVLLGLGRGSGVRSIAGMRPHDPPWCRPLLGQRRAVTHAACAELGLTAWQDPHNSDRRFARARLRAEVLPLLEEVLGGGVVEALARTATALREDNELLDALAERALPAARAGAGLQVAALAGLDAPVRRRVIRAWLLAGGATGLTDKQIRGVDNLVTAWRGQGAVAVGSSLPGERLFAGRRDGVLTLWREPVR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Gracilaria tenuistipitata var. liui
Length
320 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
38.567 kDa
Sequence
MTYTYLHNKFLSIIPKYKNLIKPLSILIALSGGKDSLCLVKLIEDFNNTYNHFSRIEYIYIDHQWRSDSKQNIKHLLNYISITNNNTYIYQINKMEISEANMRNIRYQAIVRHAIQNSHDIIVTGHNQTDQVETFLLNLMRGTGLEGLSSLPYIRKITDQIQVIRPLIHINTGDVLWFCRKFNLPIWSDKTNFYYTNFRNRIRYELLPYLKEYFHPKIESNIINFLSLSSIENEYIKQNSIKLYLASRHSHYIAINYKIIKNQHLALQKRVLNIFFYHNFNKYVNSHILNQLIKMKYQRKLTIVWETLRIKIYKNWIYIQ
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia pneumoniae
Length
319 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.499 kDa
Sequence
MVLSSDLLRDDKQLDLFFASLDVKKRYLLALSGGSDSLFLFYLLKERGVSFTAVHIDHGWRSTSAQEAKELEELCAREGVPFVLYTLTAEEQGDKDLENQARKKRYAFLYESYRQLDAGGIFLAHHANDQAETVLKRLLESAHLTNLKAMAERSYVEDVLLLRPLLHIPKSSLKEALDARGISYLQDPSNEDERYLRARMRKKLFPWLEEVFGKNITFPLLTLGEESAELSEYLEKQAQPFFSAATHQDSQGELPCPDCLIQQAFLCKWVMKKFFNNAGIAVSRHFLQMVYDHLSRSSCATLRMRNKIVIIKPGVVVID
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Nocardia farcinica (strain IFM 10152)
Length
318 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
32.846 kDa
Sequence
MLRHAVRGWLAEHLPGAAPAVAVALSGGADSLALTAAAVVEAATVDALVVDHGLQPGSDAVAVAAAAQARTLGCRSARVLRVRVGSDGGLEAAAREARYAALGSARAGLPVLLGHTLDDQAETVLLGLARGSGARSIRGMAAYTPPWGRPLLGVRRADTRRLCADLGLTPHEDPHNRSAEFTRVRLRTEVLPLLEDVLGGGVAEALARTGRQLREDGAVLDALAADLASAAADAGDLRIETLATAPAALRRRAVRAWLLDSGAKAPTDRQLRAIDALVTAWRGQGGVAVGGGTPGMRLVAARERGRLTLRRQARSPAR
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia abortus (strain DSM 27085 / S26/3)
Length
317 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.747 kDa
Sequence
MLSCLLRNDKRLEVFFSALDMKKSYLLALSGGSDSLFLLYLLKSRGVSFTAVHVDYGWRESSYREAEELKLRCQEEGVPLIVDHVPSKYTTSKDPENTARRYRYALFCKICREDNLAGIFLAHHANDQAETVLKRVLEGASLGNLKGMTSGASYNRIPLLRPLLHIPKQVLMQTLDAENIAYVHDVTNTDERYLRARMRNKIFPWLEEIFAKNITQPLLTLAQDSEELSCYMKQQAQPFLENIRQEHTTWSIEIPKPLIEQVFLAKWVCKEFFYKVGIVVSRHFLQMVYDHLSRNLPAEMRLRDKRVIVKAGVVMIE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydophila caviae (strain GPIC)
Length
317 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.954 kDa
Sequence
MLSRLLRDDKLLEVFFSSLDMKKSYLLALSGGSDSLFLLYLLKSRGVAFTAVHVDHGWRESSYREAEELKIRCEEEGIPILIDHVPPEYRTSRDPENAARRYRYTLFHKVCKEQNLAGIFLAHHANDQAETVLKRLLEGASLSNLKGMSPKTSYEDIPLFRPLLHIPKQIIINVLDAENVPCVQDITNTDERYLRARMRKKIFPWLEEIFGKNITQPLLTLAQDSEELSCYMKQQAEPFLENMRKENTTWSIEIPQVLIEQVFLTKWVCKEFFFRAGVVASRHFLQTVYDHLQRKLPAQMRLRDKRVIIKAGVVMIE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Chlamydia felis (strain Fe/C-56)
Length
317 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.8 kDa
Sequence
MLSCLLRNDKRLEVFFSSLDMKKSYLLALSGGSDSLFLLYLLKSRGVSFIAVHVDYGWRESSYREAEELELRCQAEGVPIIVDHVPPEYRTSRDQENAARRYRYALFHKVCQKKNLSGIFLAHHANDQAETVLKRVLEGAHLSNLKGMRGEVYYEGIPILRPLLHIPKIVLSRTLDAANIHYVHDITNTDERYLRARMRNKIFPWLEEIFGKNITQPLLTLAQDSEELSCYMKQQAQPFLEKIRKENTTLSLEIPKTLIEQVFLTKWVCKEFFYSAGIVASRHFLQTVYDHLNRGLPAQMRLRNKRVIVKAGVVMIE
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Aquifex aeolicus (strain VF5)
Length
317 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.32 kDa
Sequence
MNPESRVIRKVLALQNDEKIFSGERRVLIAFSGGVDSVVLTDVLLKLKNYFSLKEVALAHFNHMLRESAERDEEFCKEFAKERNMKIFVGKEDVRAFAKENRMSLEEAGRFLRYKFLKEILESEGFDCIATAHHLNDLLETSLLFFTRGTGLDGLIGFLPKEEVIRRPLYYVKRSEIEEYAKFKGLRWVEDETNYEVSIPRNRIRHRVIPELKRINENLEDTFLKMVKVLRAEREFLEEEAQKLYKEVKKGNCLDVKKLKEKPLALQRRVIRKFIGEKDYEKVELVRSLLEKGGEVNLGKGKVLKRKERWLCFSPEV
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
Length
316 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.904 kDa
Sequence
MKLSKAKQDLDHHVWKLIKLHSLQDKKILVALSGGTDSVALLRSLTKVHKKNLLGACYFHHGEDSNQEYRKEAQEFCEKLCKKLEIEFYPLRASQLAKSEAEYRELRYEALDRLKKEQGFELVATGHHRDDLLETRLIRLIRGTGAQGFAAMHVLRDGLFRPLLEISKKELKKYLREERLRSFEDPTNKALDPLRNWLREEWLKSLERRARGSTAALARSLETIAQEIENRPWGDLLGQNEAYKTQGLRRSFYLTLSPFEQKRLLAQYLFSLGKRDFSQSHLEEIQKRLDKSQKVITFKVAGCQWEVNAEQIKVQS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Cyanidium caldarium
Length
314 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
37.936 kDa
Sequence
MKVTILHQKFIRFVYLLDLELIKRKFVLGLSGGQDSLALLKLLCDYRKTYFGLLKLVYCDHRWRLESIANAQRLYYLSEYSNISFYYFATSTFLSSETQSRTWRYKNLLKISLSFEYSYLLTAHTLSDISETTIYRLVRNLRISEINNLLFTFLYIKKTLSISRPLASVTRNDTYWLCSLSYLPLWSDYTNYWLFLSRNRIRQELFPYLKNYFNCSLERYLDGFIYSNKINLITLNIKLKKILSKIFGYTNDGLYFNVSLFKLLPFFYQHILIRDFHFLFFHNYRSPSQFNRLLFAIALEKSQKVFIRKQYHII
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Length
314 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.957 kDa
Sequence
MASLIGNLELPRVSPNFLELRKAVRPYLKEHVHIGLSGGPDSLALVAAVLAEKSQVTAICIDHNLQTGSAEVTHNAAAMARHMGAQAIVKSIEVAPGEGMEAAAREARYAAFAQLTDEIWVAHTMDDQAETYLLGGLRGNPAGMKDASRRPELSIIRPLLGARRAHTHGACVELGLKPWHDPQNFDDAFRRVAIRNQVIPLLAQVHGGDPVPGLALAARRAVEDAEVVEGDVEKRRLEWQDGFPVTLAGEPTGLRRRMLADFLRGEGIAVTSRKLDAIDRLLTDWRGQGGVAVGKSDNGRLEVVRQSGKLKITD
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Length
313 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.517 kDa
Sequence
MPASIGGLPLPRICPHFLTLRVAIRAHLTDHVHIGLSGGPDSLALVAAARAEGAEVTAICINHNLQEGSAEVSERAAAQAEHMGATALIRSITVPPGSMEAQAREARYAEFAQLTDTIWAGHTMDDQAETFLLAGLRGNPAGMKSASRRPDLTVIRPLLGVRRADTHGACTELGLTPWQDPQNRDRAFRRVAIREQVLPLLAEIHAGDPVPGLALAATRAAMEGEALEFFVDKRRGEWADGFPVRLAAEPHALRRLMLADFLRGHGVRVTSKKIEAVDRLLTHWHGQGGVAVGGGAHGRLEVVRVSGKLEITG
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Cutibacterium acnes (strain DSM 16379 / KPA171202)
Length
311 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.758 kDa
Sequence
MARRELGPAALAVAQAVERMVRGVDRFVVGCSGGPDSLALALASKWASRRCESGVRVVIVDHQLQQGSDEVAERTRDLLVRRGMDACVRRVDVDADDPDGPEAAARTARRAALLDVAGDEPVLLGHTRDDQAEQVLLSLARGSGATSLAGIRPRSGQFWHPLLEVRRAQTVQACREWEVEPWQDPHNGDPRFLRSRVRTELMPVMEEVLGPEVAASLARSATLLAGEDEVVARVARMWADEHGVKANELPGLRGVEVGLARRVVKEWLPQARMVHVDAVLGLLDGPGGAGVDVPGGRVEMRQGTLYLARRL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Petrotoga mobilis (strain DSM 10674 / SJ95)
Length
311 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.881 kDa
Sequence
MILQDFEKKIFKFIRDYKIFNKYDKILLGVSGGKDSMSLLHVMSKLSKTMGFEISVAHLNHCMREEADNDEAFVRQACWKLKIPFFSKKVDVFTYSKKNKVGVEVAGRKLRYEFFYETLRRLSYNKIATAHHMDDLFETMIYRILRGTGIYGLGGLIPIEEEITKPMLCVDLEEIKNYVTINNIEYVEDKYNYSLDYARNKIRYEITPLFKKINPRYKESFFRLAKIIWSYREEVKRKFEERSEISKDSLKLRLENDFFDGEIIRIAFLKFGKYPPNMEETEKIIKMRKGGVRKINGLSITKKSDSLLVKI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Mesostigma viride
Length
310 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
36.77 kDa
Sequence
MIFLYSKIHKDIIIHNLLKKNDRILIAASGGQDSISLIKILVELQPQWNWDLGIVNCDHSWNQSSRKGSSQIAQIAQLLNIDFYQIVTCHQLINEEKAREWRYQKIEDIAFSNKYNVIVTAHNASDRIETFFFNLLRGTSITGVQSLLWTRSLSSGINIVRPLLNTTRFELKNFVKEIHLPLWPDTSNQSLFFKRNRIRKQLLPYLRKYFNPKVDKVIAQFAEIIHDESFYMENVTQIIEKQLFFGSKNIQQEFIENLPIAIERRIIKKMIEKKLSENHCNFLNIEQIRFFFQKNRKKYSLLECIHFFSN
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma hyopneumoniae (strain 232)
Length
297 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
35.736 kDa
Sequence
MQIKIKSKEKYLIGVSGGSDSMFLLNKYKNQDVIVAHINYNLRPEAIFETLLVSKFCQKYNLELKILSFDSFKIKKNLQSGLRLGRYQFFEKIYKEFNCTKLLVGHHRDDFLETVFLQKKQKKIVTFWGIHKKNNLFNMEILRPFLYWRTKKQIIRICQQKKIPYLDDQSNFTGKYQRNQIRFLLEKKSDFSLFFLFLFYYLINIFKLIILKNQKKILQNWQKTGYNINFFKKIKIKSKIIFLFVNQNFDNVKLTRGKINEIINFICGKSTSGAFLLKKNNYIIKKKWKILPKSSKI
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma penetrans (strain HF-2)
Length
295 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
35.994 kDa
Sequence
MKHKYLIAVSGGPDSMALLNKKRHLVEAVCHVNYHDREDSDNDEKIVRDYCKKYNLKLFVFDTHKDDVSKYKDINNLQTWYREIRYDFFEKISQELGIKKILIAHQKNDFLESAYMSLNKNKKNLFLGIRRKSKFRSLILIRPLLNKTKKSLEQYCRSKNIEFVIDYTNFWDRYSRNVVRKMMAEWDKKTFQKFYLKVKWFNLKNMFFIKLLDSKFNNWIKQDFDINYFLKIKNNYKESLIYLFLNHIGIKPNENKIEQIIEFINKNKNGSVKKYRLKENQFIEIKNKKILYSIC
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Length
292 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
31.282 kDa
Sequence
MHKFWPRHSPNFMACRVAVRTVQPRDITVGLSGGADSLALVAALCAEDYNVHALCVDHGLQPGSHEVAQQAAHHARTFGAHAEIISVTVAPGNLEANARTARYQALHSRNLPVVVGHTADDQAETLLLGALRGKATGMQIHTDNLWRPLLGVRRATTLAACTELGIEPWHDPHNANTDFLRVALRTQVVPLLSDIIGGDAVPALSQAATLIAEDTHALHVDTPDDRIAQLAGMPPALRRRHLVALLQAYGARVSAAHLRAVDALITNWHGQKAVPVGNGLEVTRKDGRLSVS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Length
290 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.629 kDa
Sequence
MASEKQYIAGVSGGSDSMLMLKLYQKKIACVVHVNYNTRSTSLRDQKLVEQYCQKLNIPLVVHTVDPDLVWKKNFQNQARKIRFDQFKKTAKLYQTNKLLLAHHRDDFIEQAKMQLDAKKRAVYYGIKTRCELYGLKIYRPLMKYWKDEIIALCRQDHIPYEIDETNKLPIYKRNEVRLEIEKWSKIEKEQFYIAICAMNKTIAQKLFVLMKKAKKWLLQPDVRELKRFSIIDQKQLIYSYLIYHKINVNGEKIDAILDFIQPSQQKQYRLQNDIFLMVKNQCLALLYKS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, chloroplastic
Organism
Cyanidioschyzon merolae (strain 10D)
Length
290 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.557 kDa
Sequence
MYTPMHNKFQNRFQLANLTHSHSFSHSWLLAISGGQDSLCLLKFMHDLVHHHLVVVHFDHRWSCSLAALRVYYLSRYMHLAWRYFRTALPITTEQDARQYRYANLIQLLYQTHSHAICTAHTASDDLETYLDQWISLRHPEGIWRLCHLSGSQILFRPLLHLTRAQTHWFTLVHYLPIWSDVSNYQITFKRNQLRHQLIPFLKNLNPRFHTTLSARLSARILSPLIVYPWHVWSSLPIWLQYQIATQWGLTLSQIQQLIYNNKYELARSSSINRFSFCDSSRSYHFNLAL
Protein
tRNA(Ile)-lysidine synthase, chloroplastic: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Length
289 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.385 kDa
Sequence
MPKTQYIAGVSGGPDSMLLLKLYHKKIACVVHVNYNKRTTALRDQKMVEEYCKQLKVPLIVHTVPEDTVWKKNFQAQARKIRFEQFQKAASLYKVDKLLLAHHRDDFIEQAKMQLDARKRAMYYGIKTRGELYGMKVYRPFIKYWKNEILALCEEHKVPYGIDETNAQPIYKRNQVRQEIANWSKEEKEEFYIGVCAMNRVIGQKLFSLMKRAKQWLAHPDVRELKRYPLPDQRQLVYSFLITHHIDVTGDKIDAILDFIQPFQQKHYRLKDEIFLSIKDERLTLLYKS
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
Length
287 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.273 kDa
Sequence
MSTTNKKQYLIGVSGGPDSIYLLDRYQDQIKVACHINYNKRPTALRDQLIVSDYCLKNKIPLEILSVSPSYQYHKNFQDQARKIRYDFFLSTGLKYQVDQCLIAHHKDDFLETAIMQYDKNQELLFYGLHQESSYQSLKIFRPLLNLWKDEILSYLEQDKIVYGVDESNFLSTYQRNKIRTNLSKLSQEQKQARLDFFLELNKKNQVRYQSVKDFFSSWDCNYLDLINSLEYYNLLYLWFSKNNIKYSKQKAENILSFLQKKNNKRFRLKAGVYLIKEGIKLKIVKL
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase
Organism
Mycoplasma pulmonis (strain UAB CTIP)
Length
286 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
34.833 kDa
Sequence
MKLIAVSGGPDSMLLLDVFKHHDIVVAHVNYNKRNSSKRDQKIVEDYCFKNNIKLEILNLTDYEVKGNFHDWARKKRFDFFKLVYEKYNCDEILLAHHKDDFVETFLIQKNQKRKPLYWSIKSKNFNFGMNINRPFIHKYWKNQILKILDNKQIFFGQDETNKENIYLRNKIRNNLLNKEFLKRLIYIKILFLNFFKLRKIKKIEQDFNKWKEQNFDKQNFLKSKFQENLITIFISEKTNNSINLSRGKIQQIIKFINSEKNEKKFILNKEFYLVKAKKIIKVLKK
Protein
tRNA(Ile)-lysidine synthase: tilS

Gene
tilS
Protein
tRNA(Ile)-lysidine synthase, plastid
Organism
Helicosporidium sp. subsp. Simulium jonesii
Length
280 amino acids
Function
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
Similarity
Belongs to the tRNA(Ile)-lysidine synthase family.
Mass
33.401 kDa
Sequence
MLKNIIYSYITQLKNLLSKKLNVLCTFSAGQDSFFLLYCLIHIISNKNNKIKLQHNHHFLQSSNILSFWQCIKVASIFKIPLVINLLEINLANKDFMTENEARKWRYDSFLRNSLFQNEKPSIFIGHTGSDLLETFFWHFLRNSIIDYQLIKKKLLWNIPYYISNFSSVGYKNSSKVKIKLTNKKKKINCLINHNLMLNKAKKSFLKKDLTQLVLITRPLVNLHRQDIFLFRKNLKLPVITDKSNDNNYYYRNRIRNILFPIMRILFNKKTDKNLIKLFL
Protein
tRNA(Ile)-lysidine synthase, plastid: tilS