mkrn2

Probable E3 ubiquitin-protein ligase makorin-2

423 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.

46.376 kDa

MSTKQVTCRYFLHGVCREGSRCLFSHDLNNSKPSTICKFYQRGVCAYGERCRYDHIKPSSRGGGGGAPEDQAGGGGAGGGGAGIGGAGGGPSVRGGMKKNLVLRDRVLGVDRVDRMFGAPADSMWSDVSTAAAPHSYVEAIRTGLDASAQDQATPPVCGPSQNLPQLCPYAANGHCFYEENCTYLHGDLCEVCGLQVLHPHDSEQRRAHEKMCLAAFEADMEKAFAAQLSQDKVCSICMEVVVQKANPSDRRFGILSSCCHTFCLACIRKWRCTRTFSNTIIKSCPECRVVSEFVIPSVYWVEDQEDKDHLIDLFKSGVSKKACKYFDQGRGSCPFGGKCLYLHAFPDGTRAEPDRPRKQLSSEGNVRFMNSVRLWDFIEEREQRSVPPLPALDDDMAELRELFMQMSGPSHDGPETPPTADQ

mkrn2

Probable E3 ubiquitin-protein ligase makorin-2

418 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.

46.881 kDa

MNTKHVTCRYFLHGVCREGGRCLFSHDLATSKPSTVCRFYQRGQCAYGARCRYDHVKPCNGSVFYPPQEMAPAPLESTPPLLPTQEAAAPVTKSAPQRREKKSVVLRDRDLCGASVEKAHPDPALRPGCAADPPVSELEAKPHSYLEAICTGLDETPIPSAYPDAPQQLCPFAQAGGCHYGESCPYIHGNVCEICGLQVLHPYDQEQRGHHEKLCMANFERDMERAFAFQASEGKVCSICMERVYDKQSPSERRFGILSNCHHTYCLACIRQWRCARQFENPVIKSCPECRVISEFVIPSAYWVEDQSKKFELIEAFKQGMGKKACKYFDQGRGTCPFGGKCLYLHAYPDGTRAEPEKPRKQLGSEGTVRFLNSVRLWDFIEEREQRNLPDAEDEVAELGELFMHLSGVGEEPPAASN

MKRN2

Probable E3 ubiquitin-protein ligase makorin-2

416 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

46.94 kDa

MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP

Mkrn2

Probable E3 ubiquitin-protein ligase makorin-2

416 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

46.597 kDa

MSTKQVTCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGARCRYDHTKPPAAAGGAVGPAPNPSPSSGLHSPHPSPDIATSVMRTHSNEPGKREKKTLVLRDRNLTGLAEDKTPPSKVNNPGGCSDPQTSPEMKPHSYLDAIRTGLDDLEASSSYSNEPQLCPYAAAGECRFGDACVYLHGDMCEICRLQVLHPFDPEQRKAHEKMCMSTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCSHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSEGTVRFFNSVRLWDFIENRETRQVPSTDDVDVTELGDLFMHLSGVESSEP

mkrn2

Probable E3 ubiquitin-protein ligase makorin-2

414 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.

46.48 kDa

MSTKQVTCRYFLHGVCREGSRCLFSHDLTTSKPSTICKYYQRGACAYGDRCRYDHIKPPGRGSGAPADHSNRSSSSAGASAPGPGPPANTSKHLKKPLVLRDKALCSDSRPRVFSAESSELNECWEQRDDGAQKPHSYLEAIRSGLDASAAAAATAGTFPELQQTSPQICPFLAAGQCQYGESCPYLHGEMCEICRQHVLHPHDPEQRAAHEKKCMVAFEMDMERAFAVQQSQDKVCKICLDVVYEKSSPSERRFGILSSCAHTYCLNCIRQWRCVEQLHNQIRKSCPECRVVSEFVIPSIYWVEDQEQKNLLIEEFKSGVSKKACKYFDQGRGTCPFGGKCFYMHAYADGRRAEPDKPRKQLSAEGNVRFQNSVRLWDFIEEREHRSVPQLEDEVNDLGELFMQLSGASDAPH

mkrn2

Probable E3 ubiquitin-protein ligase makorin-2

409 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.

45.999 kDa

MSPKQVTCRYFLHGVCREGSRCLFSHDLATSKPSTVCRFFLRGQCAYGTRCRYDHVKPCNGTVFIPPQEMSPVLSPPPLFPAQEAAVPPTIPAPQRREKKTLVLRDRDLCGASVDPALQPGCITESQGSEGEAKPHSYLEAICTGLDESQDPASYPGAPQQLCPFAQAGECHCGDSCPYLHGDACEICGLQVLHPHDQEQRRDHEKLCMENFELDMERAFAVQASEGRVCSICMERVYEKQSPAQRRFRILSDCNHTYCLTCIRQWRCARQFDNPVIKSCPECRVISEFVIPSAYWVEDQSKKDELIEAFKQGMGKKLCKYFDQGRGTCPFGGKCLYLHSYPDGTRAQPEKPRKQLGSEGSVRFLNSLRLWDFIEDREQRGVPNAEVGKLGELFMHLSGADEELPAPFN

mkrn2

Probable E3 ubiquitin-protein ligase makorin-2

402 amino acids

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.

44.99 kDa

MTTKQVTCRYFLHGVCREGNHCQFSHDPSSSKPSTICKFYQRGTCAYGERCRYDHVKLSSRGGGAFDMAGVGGARDGASTRGAAKKTFVHQERENMFRAPAESFGADVMAPAPHTYVDAIRTGLSSSSQDHTPPTMAGVNQDLPRLCPYAAVGHCYYEENCIYLHGDKCEVCGLQVLDPHNPEQRSMHEKMCLLAFEADMEKAFAVQLSQEKVCSICMEVVVQKMNPSDRRFGILSSCCHVFCLACIRKWRCTRNFSNKIIKSCPECRVASEFVIPSVYWEENQEDKVHLIELFKSGVGKKPCKYFDQGRGSCPFGGKCLYLHALPDGSRAEPEQPRKQLGSEGNIRFMNSVRLWDFIEEREQHSAPPLQAFADDISELRELFVQMSGPSPDEGESQSRSAP