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arsM

Gene
arsM
Protein
Arsenite methyltransferase
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
391 amino acids
Function
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals.
Similarity
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Mass
41.696 kDa
Sequence
MELWTHPTPAAPRLATSTRTRWRRTSRCSQPWATTPGTNSSDASRTPTTASASATSKPQSASARARSVRRSPDCTPRAWSRGARKDRGATTNRPRRPKFCSKRSTTCEATMSNDNETMVADRDPEETREMVRERYAGIATSGQDCCGDVGLDVSGDGGCCSDETEASGSERLGYDADDVASVADGADLGLGCGNPKAFAAMAPGETVLDLGSGAGFDCFLAAQEVGPDGHVIGVDMTPEMISKARENVAKNDAENVEFRLGEIGHLPVADESVNVVISNCVVNLAPEKQRVFDDTYRVLRPGGRVAISDVVQTAPFPDDVQMDPDSLTGCVAGASTVDDLKAMLDEAGFEAVEIAPKDESTEFISDWDADRDLGEYLVSATIEARKPARDD

Gene
arsM
Protein
Arsenite methyltransferase
Organism
Pseudomonas alcaligenes (strain ATCC 14909 / DSM 50342 / JCM 20561 / NBRC 14159 / NCIMB 9945 / NCTC 10367 / 1577)
Length
346 amino acids
Function
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals. Involved in the conversion of As(III) to dimethylarsenate as the main product in the medium and also produces dimethylarsine and trimethylarsine gases. Reduces the arsenic toxicity in the cell and may contribute to the global arsenic cycling.
Similarity
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Mass
38.023 kDa
Sequence
MHESVQNYYGKVLQNSSDLKTSACCDASSMPAWLKPLLSQVHPEVSARYYGCGLVAPALLDGCQVLDLGSGSGRDCYVLAQLVGASGSVLGVDMTAEQLAVANAHLDYHAERFGFANVSFRHGYIEDLASLELADGSFDVIVSNCVINLSPDKDSVLREAYRLLKPGGELYFSDVYADRRLADELRQDEVLYGECLGGALYWNDFEHLARRHGFTDPRLVEDQPISITDSALAEKLGDARFYSATYRLFKLDGLEPACEDYGQAVIYRGSIPGAAHAFVLDKHHRIETGRVFPVCGNTWRMLQDTRFAPHFQFIGDFSRHFGLFEGCGGGLPYDRQAAVTAATSCC

Gene
arsM
Protein
Arsenite methyltransferase
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Length
283 amino acids
Function
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals. Involved in the conversion of As(III) to a number of di- and trimethylated species, with trimethylarsine as the end product. Reduces the arsenic toxicity in the cell and may contribute to the global arsenic cycling.
Similarity
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Mass
29.656 kDa
Sequence
MPTDMQDVKDIVREKYASAALKVATGGASCCGSSALPGASPITSNLYDAAQEQGLPAEAMLASLGCGNPTALAQLSPGETVLDLGSGGGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAGLDNVEFLKGEIEAIPLPDHSVDVIISNCVINLSGDKDRVLREAFRVLKPGGRFAVSDVVTRGEIPEALRRDVLLWVGCLAGALDEADYVAKLAAAGFAQISIEPTRVYDIEDAREFLTGKGIDVDALAPQMQDKFFSGFVRATKPGADGEVPARCCG

Gene
arsM
Protein
Arsenite methyltransferase
Organism
Clostridium sp
Length
270 amino acids
Function
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals. Involved in the conversion of As(III) to monomethylarsenic and the conversion of monomethylarsenic to dimethylarsenic. Reduces the arsenic toxicity in the cell and may contribute to the global arsenic cycling.
Similarity
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Mass
29.061 kDa
Sequence
MDNIREGVRQKYAFAIANRGQGCCGSPGCCSDGLSDAADPITGNLYDESDLQGLDPELIANSFGCGNPTALMNLNLGEVVLDLGSGSGLDVLLSAKRVGPTGKAYGLDMTDEMLAVAKENQRKSGIENAEFLKGHIEEIPLAAKSIDVIISNCVINLSGDKDKVLKEAYRVLKPQGRFAVSDIVIKRPLPEKIRDNILAWAGCIAGAMTEEEYRGKLSRAGFENISLQVTREYNLEDPSLRGMLEDLTDGEIKEFQGAMVSCFIRAAKPA

Gene
arsM
Protein
Arsenite methyltransferase
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
249 amino acids
Function
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals. Involved in the conversion of As(III) to a number of methylated products. Reduces the arsenic toxicity in the cell and may contribute to the global arsenic cycling.
Similarity
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Mass
26.671 kDa
Sequence
MDAAEKKEVIKKKYQEIATLGGSCCSGGGCCGDLSAADLSRSLGYSEADVQAVPDANLGLGCGNPTAFAELKPGDIVLDLGSGAGFDSFLAAQRVGSLGKVIGVDMTQEMVKKAQDNARKYGYSNVEFRQGDIEALPLDDRSVDVIISNCVINLAPDKEKVFREAFRVLKPGGRMYVSDMVLLEDLPEDLKNDCDLLAGCVAGALLKEEYLGLLKKAGFSFKILAEDSDVSKRQYEGLPVESLKLKAWV