Protein
Arsenite methyltransferase
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Function
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals. Involved in the conversion of As(III) to a number of di- and trimethylated species, with trimethylarsine as the end product. Reduces the arsenic toxicity in the cell and may contribute to the global arsenic cycling.
Similarity
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Sequence
MPTDMQDVKDIVREKYASAALKVATGGASCCGSSALPGASPITSNLYDAAQEQGLPAEAMLASLGCGNPTALAQLSPGETVLDLGSGGGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAGLDNVEFLKGEIEAIPLPDHSVDVIISNCVINLSGDKDRVLREAFRVLKPGGRFAVSDVVTRGEIPEALRRDVLLWVGCLAGALDEADYVAKLAAAGFAQISIEPTRVYDIEDAREFLTGKGIDVDALAPQMQDKFFSGFVRATKPGADGEVPARCCG