TTC30A

Tetratricopeptide repeat protein 30A

665 amino acids

Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.

Belongs to the TTC30/dfy-1/fleer family.

76.136 kDa

MAGLSGAQIPDGEFTALVYRLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVGNTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARHNRDDEAIKKAVNEYDETMEKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKHMIVIHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTVTDESRQLKALIYEIIGWNK

TTC30A

Tetratricopeptide repeat protein 30A

664 amino acids

Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.

Belongs to the TTC30/dfy-1/fleer family.

76.303 kDa

MAGLGGEPIPDGEFTAVVYRLIRDARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLRQLHPELEQYRLYQAQALYKACLYPEATRVSFLLLDNPTYHNRVLRLQAAIKYSEGDLPGARSLVEQLLSEGGEDSGGENELDGQVNLGCLLYKEGHYEAACSKFSAALQASGYRPDLSYNLALAYFSSRQYASALKHIVEIIEHGIRQHPELGVGMTTEGIDVRSVGNTLVLHQTALVEAFNLKAAIEYQLRNYEAAQETLTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQIPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFVKLDGLAGMLTEQLRRLTKQVQEARHNKDDEAIKKAENEYDDTLEKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNILKVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKIYHFCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKHMIVLRDSVIQECVQFLEHCELYGRNIPAVIEQPLEEERMHTGKNTVTYESRELKALIYEIIDWNM

ttc30a

Tetratricopeptide repeat protein 30A

651 amino acids

Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation.

Belongs to the TTC30/dfy-1/fleer family.

75.523 kDa

MPPMTIKDGEYTATVYKMIKEGRYGDAIHILSKEHQKHTKSRAALSLLGYCYYHMQDFTNAAECYEQLTQLHPEVEDYKLYYAQSLYGACAFPEAMKSTFLLDNTTSHTKMIKLQAAIKYGEEDYSGAKTLVEQLPQEDPDYDVDLGCLLYKEGEFEEACKKFMSSMNVLGYQPDLAYNIALCYYSLKQYASALKYIAEIIERGIREHPELSIGMTTEGIDVRSVGNTLILHETALIEAFNLKAAIEYQLKNYAAAQEALTDMPPRSEEELDPVTLHNQALMNMDTKPTEGFEKLAFLLQQNPFPPVTFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYEFLDAMITCQTAPEEAFRKFDENAGKLTEQLRKVTKQVQEARHNRDDESLKKYVQDYDEVLEKYIPVLMAQAKIYWNRENYSMVEKIFHKSLEFCNEHDTWKLNVAHVLFMQDNKYKEAIGFYEPIVKKHYENILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQISYDDPDKKIFHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWFYAKRCFLSLLENMAKHMIMLRDSVVQECIQFLEHCELYGKDVLAIIEQPLEEDRMHIGKNTVTYESRLIKALFYEVTGWNE

ttc30a

Tetratricopeptide repeat protein 30A

651 amino acids

Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.

Belongs to the TTC30/dfy-1/fleer family.

75.559 kDa

MAVRQIKDGEYTATIYRLIKEARYGEAIQVLSNELQKQYRSRAGLSLLGYCYYQIQDFVNAADCYEQLIQISPEVEEYKLYYAQSLYKACMYPEAMKATFALDNAAYQSKMLKLQASVKYGEEDISGAKSLVEQMPSEDPESEINMGCLLYKEGHYEEACKKFITAMQVMGYKQDLSFNIALCYYSMKQYAPALKHIADIIERGIREHPELGVGMTTEGIEVRSVGNTLVLHETALIEAFNLKAAIEYQLKNYEAAQEALTDMPPRSEEELDPVTLHNQALMNMDTKPTEGFEKLQFLLQQNPFPPETFGNLLLLYSKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFLKLDELAGMLTEQMRKLTKQVQEARHNRDDEAVKKAVNEYDETLEKYIPVLMAQAKIYWNMENYQMVEKIFRKSVEFCNEHDIWKLNVAHVLFMQDNKYKEAIGFYEPIVKKHYDNILNVSAAVLANLCVSYIMTSQNEEAEELMRKIEKEEEQIAYENPDKKIYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYHAKRCFLSLLENMSKHMIMLRDDVIVECIQFLEHCEIYGRNILAVIEQPLEEERMHIGKNTVTYESRQLKALLYEITSWNL

ttc30a

Tetratricopeptide repeat protein 30A

651 amino acids

Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.

Belongs to the TTC30/dfy-1/fleer family.

75.584 kDa

MAARQIKDGEYTATIYKLIKEARYGEAIQILSNELQKQYRSRAGLSLLGYCYYQIQDFVNAADCYEQLIQITPEVEEYKLYYAQSLYKACMYPEAMKATFALDSSAYQSKMLKLQASIRYGEEDISGAKSLVEQMPSEDPESEINMGCLLYKEGHYEEACKKFITAMQVMGYKQDLSYNIALCYYSMKQYAPALKHIADIIERGIREHPELGVGMTTEGIEVRSVGNTLVLHETALIEAFNLKAAIEYQLKNYEAAQEALTDMPPRSEEELDPVTLHNQALMNMDTKPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFFKLDELAGMLTEQMRKLTKQVQEARHNRDDEAVKKAVNEYDETLEKYIPVLMAQAKIYWNMENYQMVEKIFRKSVEFCNEHDIWKLNVAHVLFMQDNKYKEAIGFYEPIVKKHYDNILNVSAAVLANLCVSYIMTSQNEEAEELMRKIEKEEEQIAYENPDKKIYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYHAKRCFLSLLENMSKHMIMLRDDVIAECLQFLEHCEIYGRNIPAVIEQPLEEERMHIGKNTVTYESRQLKALLYEITSWNL