Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.

Belongs to the TTC30/dfy-1/fleer family.

664 amino acids

MAGLGGEPIPDGEFTAVVYRLIRDARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLRQLHPELEQYRLYQAQALYKACLYPEATRVSFLLLDNPTYHNRVLRLQAAIKYSEGDLPGARSLVEQLLSEGGEDSGGENELDGQVNLGCLLYKEGHYEAACSKFSAALQASGYRPDLSYNLALAYFSSRQYASALKHIVEIIEHGIRQHPELGVGMTTEGIDVRSVGNTLVLHQTALVEAFNLKAAIEYQLRNYEAAQETLTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQIPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFVKLDGLAGMLTEQLRRLTKQVQEARHNKDDEAIKKAENEYDDTLEKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNILKVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKIYHFCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKHMIVLRDSVIQECVQFLEHCELYGRNIPAVIEQPLEEERMHTGKNTVTYESRELKALIYEIIDWNM

76.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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