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RIC3

Gene
ric3
Protein
Protein RIC-3
Organism
Xenopus tropicalis
Length
375 amino acids
Function
Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors (By similarity).
Similarity
Belongs to the ric-3 family.
Mass
40.774 kDa
Sequence
MALSAVQKVVLFSCLVLCVSLLLPRAYIARGKPAAQEGNTGLFQSSGHHPKPTDGRPGGAHFPRSHMAEAMSKAKGGTGGGGGGGTRPSLVGQIIPIYGFGILLYILYILFKLSSKGKSTKQEPTTQPVANGNLKRKITDYELSQLQDKLKETEEAMEKIISRLGPNSERTDNVSSDEETDLLQRLKEITRVMKEGKILDGISPEKEAEEAPYMEDWNGYPEETYPVYDPSDCKRTQQTILVDCSALNRPSAEQVAEQMGFDEEDDQENGSGNLAKEPDYKDSVGGDQQAQGTISAQGKVVGTGEDIEEDEDEDEDPEVIAENAGFISDSCNEEEDPKESFMDLGNEKGPLGATLGSNRDETGTLRKRNTKGIEY
Protein
Protein RIC-3: ric3

Gene
RIC3
Protein
Protein RIC-3
Organism
Homo sapiens
Length
369 amino acids
Function
Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.
Similarity
Belongs to the ric-3 family.
Mass
41.092 kDa
Sequence
MAYSTVQRVALASGLVLALSLLLPKAFLSRGKRQEPPPTPEGKLGRFPPMMHHHQAPSDGQTPGARFQRSHLAEAFAKAKGSGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTTAEDGKCYTAMPGNTHRKITSFELAQLQEKLKETEAAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFIDRFSPEKEAEEAPYMEDWEGYPEETYPIYDLSDCIKRRQETILVDYPDPKELSAEEIAERMGMIEEEESDHLGWESLPTDPRAQEDNSVTSCDPKPETCSCCFHEDEDPAVLAENAGFSADSYPEQEETTKEEWSQDFKDEGLGISTDKAYTGSMLRKRNPQGLE
Protein
Protein RIC-3: RIC3

Gene
Ric3
Protein
Protein RIC-3
Organism
Mus musculus
Length
367 amino acids
Function
Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.
Similarity
Belongs to the ric-3 family.
Mass
40.283 kDa
Sequence
MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLDRFPPMMHHHSAPSDGQTPGARFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTAEDRNCSTAPPGNAHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQAVTSDQEKRLLHQLREITRVMKEGKFIDTSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDLKEPSAEEIAEQMGEIEEEGSERLSWDHLPTDPGAQKDNSVAPCDPKPESCSCCVHEEEDPAVLAENAGFSADGYSEQEEATKENLPQDFTNEGLGVSTDNAHVGGMLRKRNPQGFE
Protein
Protein RIC-3: Ric3

Gene
RIC3
Protein
CRIB domain-containing protein RIC3
Organism
Arabidopsis thaliana
Length
220 amino acids
Function
Functions as downstream effector of Rho-related GTP binding proteins of the Rho of Plants (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Functions as downstream effector of ARAC11/ROP1 to activate calcium signaling that leads to F-actin disassembly associated with exocytosis in the tip of the growing pollen tube. Counteracts the ARAC11/ROP1-RIC4 pathway, which promotes apical F-actin assembly associated with vesicle accumulation, to control actin dynamics and pollen tube apical growth.
Mass
24.256 kDa
Sequence
MATVKGLLKGLRYITQIFDEEKDKDMQIGFPTDVKHVAHIGSDGPATNVPSWMGDFKPQENENGQVVSRADANNNQIGEGVGLQELLPPTDKPKHKKTRRKSETVSQNGSPPRRNSSASASDMQPKNTRRHHRSRHGSIDSSNDPSVRRRRVVSVTTNDMEGSYPLSDSSTHSRKSTSRHRKPKGSGGGELSMKKTKGKTENPIVESVDTCNDNNISDKE
Protein
CRIB domain-containing protein RIC3: RIC3