Function
Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424). May be involved in the 3'-end processing of the spliceosomal snRNAs U1, U2, U4 and U5 but is probably not essential for 3'-end processing of the snRNA U7 (PubMed:21078872, PubMed:23097424).
Sequence
MPSQEENELYMVKEAQRLRKSDPCAAMAWIITAKTLYPNAFNLQYEAYLLERDAQNYEEAAKCFSAIATNFQNQHTELWQEINSLTNALRNENETTPEHEFYVKMYKHLTPEVQHNIFMHTINHSADNLERIYIYILMFNKFPKSAITQAPRLLEMLAEGMKTEPDLYQRILVEEVLPMIQNKPPELSPNLACRLYTSSLEFYLRQIMDESDTADAWKNIFKVLMICGQMMGWEPFLPFSKHVNQNVYWEKLVDILSGSPAGSSQVLFYATTLFIYSLHGYIRNCKLRIEDADVTHVLVEGFMEWSPEGDGSEVPSMEPPKFSLTTAISPELSKAFLHAAQCWQLLNTDQFQRDFSQLMLALPLAPWISRFLFDLAIYFGHRDEANKLMADMTTQSSLVQSLQILSLNLMQGSMTLQGFQCILKILSELPTTQGQLLENMSLKGHRHMVFLPLTRSALVQYCVGAIISRLSRKVFEPNVPDRLLGDILVLQQLNLLNDVLLTQQIFNLIKQRKSFNLRTLSTYIINIDLLEELSHIWNSQQEDNFELTSSPNSSGTPTATTVAGGSQSRRIGTRGADKGARDEFRAITRQQIARCNENVITLLANFINQEHLMLAQHIFGISQPVETIVIK