Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

Belongs to the Integrator subunit 10 family.

715 amino acids

MSAQGDCEFLVKRARELVPQDPYAAKAWLITARTLYPTDFNIQYEMYSIERNAERTSSAGRLLYDIFVNFPDQPVVWREISAITAALRNDSQDKHAQFLKGVFETLPGQVQCKMLLKATEQCFNTLEKAEMLLLLLKRFPESVVQHGVSLGESLLEAESVEDLETPVNCFRKLFVCDVLPLILNNPEMCLPVSLLYKYLHKAAEFYICYVTREPSADGQMQGSQEVGGLNSPGRGRGQRSVIDGLSDKASVVTEPWDRLLEMVGVVGSLCDWQGEKGSRSYAELLQRVSDLCRFLSAADADGFSRCCSQIVSCCTLVLFHCAFHYVSAVQPSLFQGHSSLSSGPWVLLEDLSSVYADVEVERKHTHKKRKLADGREKTMSSDDEDVLAKGRGRHIVVSKSEMLNWAETLDHFRTARESWDLLHSHPSLEAEFAKICSAWKTEMWLWFRIFLTDMIIYQGQYRKALSSLALMSSLQLQQNQNQNQNSLQTGSSSSLENHRAVIQQASCHYALGEYRLACEKLLEAVGGLLPQNQEFVKSSDEQRKPRSKTRRGNDLRLVPCTSKSILPFCLQLMLACFKLRAFTDNRDDLALGHVIVLLQFDWPQGESLFLKAVDKICQQGSFQYENFFNYVTNIDMLEEFAYLRTTEGGRVQLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLLMVLHRFCINEKIILIQSLP

81.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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