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HIKESHI

Gene
HIKESHI
Protein
Protein Hikeshi
Organism
Bos taurus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.653 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFSYPDSNGMPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGTMNIVRTPSVAQIGISVELLDSLAQQTPVGNAAVSSVDSFTQFTQKMLDNFYNFASSFAVSQAQMTPSPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: HIKESHI

Gene
HIKESHI
Protein
Protein Hikeshi
Organism
Gallus gallus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.773 kDa
Sequence
MFGCLVAGRLVQAAPQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFCYPDQSGMAVWQLLGFVTNEKPSAIFKISGLKSGKGSQHPFGAMNLPQTPTVAQIGISVELLENLVQQTPVANAAVSSVDSFTEFTQKMLDNFYNFASSFAVTQAQMTPNPSEAFIPANVVLKWYENFQRRLTQNPLFWKT
Protein
Protein Hikeshi: HIKESHI

Gene
hikeshi
Protein
Protein Hikeshi
Organism
Danio rerio
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound hsp70 proteins into the nucleus. hsp70 proteins import is required to protect cells from heat shock damages (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.444 kDa
Sequence
MFGCLVAGRLVQTDAQQVASDKFVFNLPDYEHVNHVVVFLLGTVPFPEGLGGAVYLCVPGGAAGQVWQLLGFITNEKPSAIFRISGLKAGEGSSHPFGMMDAPAAPSMAQVGVSVEGLHLLAQQTPVSSSAVSTLDSFTQFTQKMLDSLFNFTSSFALSQSQMSPNPSEMFIPASSIRRWYENFQRRLMQNPNFWKT
Protein
Protein Hikeshi: hikeshi

Gene
HIKESHI
Protein
Protein Hikeshi
Organism
Homo sapiens
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
Similarity
Belongs to the OPI10 family.
Mass
21.628 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYESINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGMPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSMAQQTPVGNAAVSSVDSFTQFTQKMLDNFYNFASSFAVSQAQMTPSPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: HIKESHI

Gene
Hikeshi
Protein
Protein Hikeshi
Organism
Mus musculus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity). May also be indirectly required for organization and/or function of the secretory apparatus in Clara cells in lung.
Similarity
Belongs to the OPI10 family.
Mass
21.619 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSLAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTPNPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: Hikeshi

Gene
Hikeshi
Protein
Protein Hikeshi
Organism
Rattus norvegicus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.619 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSLAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTPNPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: Hikeshi

Gene
HIKESHI
Protein
Protein Hikeshi
Organism
Bos taurus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.653 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFSYPDSNGMPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGTMNIVRTPSVAQIGISVELLDSLAQQTPVGNAAVSSVDSFTQFTQKMLDNFYNFASSFAVSQAQMTPSPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: HIKESHI

Gene
HIKESHI
Protein
Protein Hikeshi
Organism
Gallus gallus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.773 kDa
Sequence
MFGCLVAGRLVQAAPQQVAEDKFVFDLPDYENINHVVVFMLGTVPFPEGMGGSVYFCYPDQSGMAVWQLLGFVTNEKPSAIFKISGLKSGKGSQHPFGAMNLPQTPTVAQIGISVELLENLVQQTPVANAAVSSVDSFTEFTQKMLDNFYNFASSFAVTQAQMTPNPSEAFIPANVVLKWYENFQRRLTQNPLFWKT
Protein
Protein Hikeshi: HIKESHI

Gene
hikeshi
Protein
Protein Hikeshi
Organism
Danio rerio
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound hsp70 proteins into the nucleus. hsp70 proteins import is required to protect cells from heat shock damages (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.444 kDa
Sequence
MFGCLVAGRLVQTDAQQVASDKFVFNLPDYEHVNHVVVFLLGTVPFPEGLGGAVYLCVPGGAAGQVWQLLGFITNEKPSAIFRISGLKAGEGSSHPFGMMDAPAAPSMAQVGVSVEGLHLLAQQTPVSSSAVSTLDSFTQFTQKMLDSLFNFTSSFALSQSQMSPNPSEMFIPASSIRRWYENFQRRLMQNPNFWKT
Protein
Protein Hikeshi: hikeshi

Gene
HIKESHI
Protein
Protein Hikeshi
Organism
Homo sapiens
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
Similarity
Belongs to the OPI10 family.
Mass
21.628 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYESINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGMPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSMAQQTPVGNAAVSSVDSFTQFTQKMLDNFYNFASSFAVSQAQMTPSPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: HIKESHI

Gene
Hikeshi
Protein
Protein Hikeshi
Organism
Mus musculus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity). May also be indirectly required for organization and/or function of the secretory apparatus in Clara cells in lung.
Similarity
Belongs to the OPI10 family.
Mass
21.619 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSLAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTPNPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: Hikeshi

Gene
Hikeshi
Protein
Protein Hikeshi
Organism
Rattus norvegicus
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.619 kDa
Sequence
MFGCLVAGRLVQTAAQQVAEDKFVFDLPDYENINHVVVFMLGTIPFPEGMGGSVYFSYPDSNGVPVWQLLGFVTNGKPSAIFKISGLKSGEGSQHPFGAMNIVRTPSVAQIGISVELLDSLAQQTPVGSAAVSSVDSFTQFTQKMLDNFYNFASSFALSQAQMTPNPSEMFIPANVVLKWYENFQRRLAQNPLFWKT
Protein
Protein Hikeshi: Hikeshi

Gene
hikeshi
Protein
Protein Hikeshi
Organism
Xenopus laevis
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound hsp70 proteins into the nucleus. hsp70 proteins import is required to protect cells from heat shock damages (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
21.983 kDa
Sequence
MFGCLVAGRLVQTDAQQVAEDKFVFNLPDFESINHVVVFMLGTVPFPERMGGSVYFSFPDQTGMPVWTLLGFITNEKPSAIFKISGLKSGEGSQHPFGTMNLPQTPSVAQIGISVELLEQMAQQTPVANAAVSTVDSFTQFTQKMLDNFYNFATSFAVSQAQMIPNPSEVFIPSNVVLKWYENFQRRMAQNPFFWKT
Protein
Protein Hikeshi: hikeshi

Gene
hikeshi
Protein
Protein Hikeshi
Organism
Xenopus tropicalis
Length
197 amino acids
Function
Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound hsp70 proteins into the nucleus. hsp70 proteins import is required to protect cells from heat shock damages (By similarity).
Similarity
Belongs to the OPI10 family.
Mass
22.003 kDa
Sequence
MFGCLVAGRLVQTDAQQVAEDKFVFNLPDYESINHVVVFMLGTVPFPERMGGSVYFSYPDQSGMPVWTLLGFITNEKPSAIFKISGLKSGEGSQHPFGTMNIPQTPSVAQIGISVELLEQMAQQTPVANAAVSTIDSFTQFTQKMLDNFYNFATSFAVSQAQMTPNPSEVFIPSNVVLKWYENFQRRMAQNPFFWKT
Protein
Protein Hikeshi: hikeshi