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EGD2

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
Length
214 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
23.114 kDa
Sequence
MSNPRIEELPDNEEPTKQQVTAEDEGSDSSDSEGEGEVESGIPAGAGAVVHSRNEKKARKSIAKLGLTRVPGITRVTLRRPKNILFVINNPEVYKSPTSNTYIVFGEAKIEDLNSQAQASAAAQLAAQESHDHAGHDHSGHDHSHDHGKGKAVDTGDEKKEEEEDDTEEVDATGLEDKDIELVMTQASVSRNKAVKALKENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Botryotinia fuckeliana (strain B05.10)
Length
212 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
23.081 kDa
Sequence
MSNPRIEELPDNEEPTKQQVTAEDEGSDSSDSEAEGEEVAGIPAGSQVAFSRNEKKARKSIAKLGLTRVPGITRVTLRRPKNILFVINQPEVYKSPTSNTYIVFGEAKIEDLNSQAQASAAAQLAAQESHDHAGHDHSGHDHSHDHGKGKAVDTEEKKEEEEDDTEEVDATGLEDKDIELVMTQASVSRNKAVKALKENDNDIVNSIMALSI

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
211 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
23.324 kDa
Sequence
MSNPRIEELPDEPEKKNVQIEEDESSDESEGEEGEANIPAGASVAVHSRNEKKARKAIAKLGLKHIDGITRVTLRRPKNILFVINQPDVYKSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAQAEAASHDHSGHDHDHDHKGKGKAVEDKKDDEEDEEEEEEDDEEVDDSGLEAKDIELVMQQASVSRKKAVKALKENDNDIVNSIMALSI

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
209 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
23.179 kDa
Sequence
MSNPRVEELPDEEPKKTTVQEHEDDSSDDSEVEEVGEGQLPAGSTVIHNRNEKKARKALEKLHLTRIPGITRVTLRRPKNILFVINTPEVYKSPNSNTYIVFGEAKIEDVNAAAQQAAAAQLASQNAEDHSGHNHGEPSKAVEADEKKEDKEDDEDEEEEEEEEVDASGLEDKDIELVMTQANVSRNKAVKALKENDNDIVNSIMALSI

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Ajellomyces capsulatus (strain NAm1 / WU24)
Length
208 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
22.216 kDa
Sequence
MSSSRIEELPDDDVPKTTVEDAADSSESEVEGAEEPTIPGGAAVTVHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKGILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAGSNEHAGHDHASHDHGKGKAVESADKKDEEEDDEEVFDASGLEAKDIELVMAQASVSRNKAIKALKENDNDIVNSIMALSV

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Coccidioides immitis (strain RS)
Length
205 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
22.081 kDa
Sequence
MANPRVEELPDEEVPKTTVEDAGESSESEAEAAEEPTIPGGAAITVHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLSAAEAAGNGEHAGHEHIDLGKGKAPETEKKEEEEEEEGEVDETGLEAKDIELVMAQANVSRSKAIKALKENDNDIVNSIMALSV

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Length
204 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.972 kDa
Sequence
MADPRVEELPDEEVPKANVEDAGSDSESEAGEESSIPAGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAAGEHAGHDHDHDHGKGKAPETEAKKEEEEDDGEEVDETGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
204 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
22.032 kDa
Sequence
MADPRVEELPDEEVPKTNVEDAGSDSESEAGEESSIPSGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPTSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAAGEHAGHDHDHDHGKGKAPETEAKKEEEEDDGEEVDETGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
204 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.972 kDa
Sequence
MADPRVEELPDEEVPKANVEDAGSDSESEAGEESSIPAGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAAGEHAGHDHDHDHGKGKAPETEAKKEEEEDDGEEVDETGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
203 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.972 kDa
Sequence
MADPRIEELPDEEVPKTNVEDAADSSESEAGEEPTIPGGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAGEHAGHDHDHDKGKGKAPETEAKKEEEEDDGEEVDETGLEPKDIDLVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Length
202 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.826 kDa
Sequence
MADPRVEELPDEEVPKTNVEDAGSSSESEAGDEPTIPGGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNATAQATAAQQLAEAAANEHAGHDHEHDHGKGKAPEAEAKKEEEEDDGEEVDESGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
202 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.804 kDa
Sequence
MADPRVEEIVEEETPKQTVEDAGSDSESEAGEANIPAGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAAGEHAGHDHEHDLGTKVPEAETKKEEEEDDGEPVDESGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Length
202 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.912 kDa
Sequence
MADPRVEELPDEEVPKTNVEDAGSDSESEAGEEPTIPGGAAVAVHSRNEKKARKAIGKLGLKLVPGITRVTFRRPKNILFVINQPEVYRSPSSNTWIIFGEAKIEDLNAQAQASAAQQLAAQEAAQEHAGHEHEDILGKAKEPEAEKKEAEEDDGEEVDESGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Length
201 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.82 kDa
Sequence
MANPRVEELPDEEVKKTVVDDHDDDSSSDSDGEEETNLPAGSTAVIHSRNEKKARKAIEKLHLIRVDGITRVTLRRPKNILFVINNPEVYKSPNSGTYIVFGEAKIEDLNASAQAAAAQQLASSAGHDHDHAGHSHGEAKASEGDAKKEEEDDDEEVDADGIEDKDIELVMTQAGVSRTKAIKALKENDNDIVNSIMALSV

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
Length
200 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
22.053 kDa
Sequence
MADPRIEELPDEETKKPTVEELDESSDEESDAEAGDASLPAGSTAVIHSRNEKKARKAIEKLHLTRVPGITRVTLRRPKNILFVINNPEVYKSPNSNTYIVFGEAKIEDLNASAQAAAAQQLANQTAEHDHAGHTHDHKHEAAKEEEEEEDDGEEVDAEGIEDKDIELVMTQANVSRKKAIKALKENDNDIVNSIMALSV

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
198 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
21.168 kDa
Sequence
MSAENKIEEITEDQVPQIEENSTIVIKKEEKAARALISKLNLQKVEGITRVVLKRTRQHIFVIANPEVYKTPTGNSYVVFGEAQHEDMQATARAAQIAAAQAQQAAAETGSVSEAAAAGEVGAELASKDPASITADLEAASLSKDEDAEDEAEADATGLEDSDIKLVMEQANVSRNKAINGLKKNDSDVVNTIMDLCK

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
191 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
20.275 kDa
Sequence
MSIENLHIADETEIPAGATVELHSRPERKARKALEGLGLKRVQGIQRVTLRRARNVLLVVSSPEVYKSPGSDCYIVFGEAKVEDPNSAAQLQAQAQLAASSQAAQQAHAHGGFKEGVPKSLEELMQDAPSADSSAPAPSGEATDASASGDFKVSDEEIQLIVAQTGVDEAKAREAYISEKGDLINAIMKLQ

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
191 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
20.305 kDa
Sequence
MSIENLHIADETEIPAGATVELHSRPERKARKALEGLGLKRVQGIQRVTLRRARNVLLVVSSPEVYKSPGSDCYIVFGEAKVEDPNSAAQLQAQAQLAASSQAAQQAHAHGGFKEGVPKSLEELMQDAPSTDSSAPAPSGEATDASASGDFKVSDEEIQLIVAQTGVDEAKAREAYISEKGDLINAIMKLQ

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
190 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
20.651 kDa
Sequence
MSATVEEIADDVQDLNVQEFDSDDAGADVHASDKVASRAERKSRKALQGIGLKKVGGITRVTMRRPRGHLYVIAQPEVYKSSHSDVYIVFGEAKAEDMSQLAQAQAAQQMAQAEAQERLLAESLQNSSASGAEKKVEEEEEDDDSPIDEEGVDAKDIDLVMQQVSCSRRKAVKALKESNGDLINAIMNAS

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)
Length
182 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
19.552 kDa
Sequence
MSIEEIPQGADVSIVPNKNEKKAKELIKKLGLKQIKGISRVTFKQRGNLIYAIDAPEVYRSQAGTYVVFGEAKVDDMNQRIAEAQAQQAQQEALQKAAADAGAAGDDKSPEAITADLEKASLQGGESNADAAEDDNEEVDETGINPKDIDLIVEQTRVSRGSAVKALKKHDGDMVNALMELS

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
180 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
19.706 kDa
Sequence
MSIEEIPQGADVSILSKNEKKARELIKKLNLKQIKGITRVTFKQRGNLIYAIDQPDVFRSSAGTYVVFGEAKVDDMNKRIAEAQQQQAQQDALSKAAGETGEAGEEDKSQDAITADLEKASLNTNKIEEEEADDGEVDESGLDAKDIDIIVEQTQVSRAKAVKALRVHDGDMVNAIMELS

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)
Length
178 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
19.548 kDa
Sequence
MSIEEIPEEIPQGADVTILSKNEKKARELIKKLHLKPVPGITRVTFKQKGNLIYAIEQPDVFKSAAGTYVVFGEAKVDDMNKRIAEAQAQQEQQEALTKAAADAETADKSPESITNDLQNASLEDKTVEEDEGEVDETGLDSKDIEIIVEQTQVSRAKAVKALRAHKGDMVNAIMELS

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
178 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
19.51 kDa
Sequence
MSIEEIPQGADVNVIPKNEKKARELIKKLNLKQIKGISRVTFKQRGNLIYAIDSPDVYRSAAGTYVVFGEAKVDDMNQRIAEAQAQQAQQEALQKAAADAGKTEDKSPEAITADLEKASLGDKKAEDEEEDEGEIDETGLDPKDIEIVVEQTQVSRAKAVKALRNHDGDMVNAIMDLS

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
176 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
19.309 kDa
Sequence
MSIEEIPQGADVNVIPKNEKKARELIKKLNLKQIKGITRVTFKQRGNLIYAIDAPDVYRSAAGTYVVFGEAKVDDMNQRIADAQAAQAAETDAHAGHTHSHGEEDKSPEAITADLEKASLTEKIEEEEEEGEVDESGLDAKDIDIIVEQTQVSRAKAVKALRKHDGDMVNAIMELS

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
176 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
18.86 kDa
Sequence
MSEIAQDSNVSIFSKNEKKARELILKLGLKPIQGVSRVTFKKKDGQIFAIDRPEVYKSQGGNFVVFGEAKVDDFTQRLAKAQESLQQNEGVLPAGQDAVSKDPQSIQADMQAAADSATDKPSADDAVDDAEVDETGLNADDIELVMQQAGVPRAKAAKALKEHDSDIVNAIMALSG

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Saccharomyces cerevisiae (strain YJM789)
Length
174 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
18.709 kDa
Sequence
MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKDNQIYAIEKPEVFRSAGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSPEDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKAHNGDLVNAIMSLSK

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
174 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
Similarity
Belongs to the NAC-alpha family.
Mass
18.709 kDa
Sequence
MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKDNQIYAIEKPEVFRSAGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSPEDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKAHNGDLVNAIMSLSK

Gene
egd2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
173 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Ucp15 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
18.785 kDa
Sequence
MSVESQPVEKISELPAGSTTVVHAEKAQKLIQKLGLKRVEGITRVAMRRPKNILLIINEPIVYKSSNNAYIVLGKVTVEDMAAQARAFNESQKQATETKEEAAITEESGDAQPADTAKIEESFEQEKAVDETGVDAKDIELVMAQANVSRAKAVTALKENNSDVVNAIMSLTM

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
Length
169 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
18.185 kDa
Sequence
MSAIPEGSNVTVLNKNEKKAREMISKLGLKKIAGINRVTFRKKDNQIFAIDNPEVYRSQGGNYVVFGEAKIDNFSQKLAAAQEKIQSVSKSPEEIQKDMQLAADQAGDESAKPAAAAEEDDEAPVDAGDLSAEDIELVASQANVSKNKAIKALKEHNGDIVNAIMALSK

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
168 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
18.217 kDa
Sequence
MSEIPENSKVSIYSKNEKKARELIQKFSMKPMPGITRVTFRKKNNQIFAIDNPDVYKTQGGNYVVFGEPKVDDFTRRLARAQQQAASAAKDPQSIQADMAAAAAAPAAPAAPAAAPEEDEAGQVDESGLDGQDIELVMQQANVSRNKAVKALREHNSDIVNAIMSLSK

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
165 amino acids
Function
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
17.894 kDa
Sequence
MAEIPEGANVTILNRNEKKARELISKLGLKKVPGIIRVTFRKKDNQIFAIEKPEVFRSVGGNYVVFGEAKVDNFTQRLAAAQQQAQSQTATKTPEDIQADMQAAAVANENKTEGDAAEEDVDAGDLSNDDIDLVVQQTNATKGQAIKALKEHNGDIVNAIMSLSK

Gene
EGD2
Protein
Nascent polypeptide-associated complex subunit alpha
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
157 amino acids
Function
May be involved in mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Similarity
Belongs to the NAC-alpha family.
Mass
17.517 kDa
Sequence
MARALTTDESHIHKTLGAKVGLEEVEAVERIAIVVKDTRYSVESPVAYRIKGTDSILIFGDLGSPVNLHQLKRMYEDSIRSSKDQEGPGLYDEIHSDPQEDGVKEAEEITVDPSDERLSEEDIKLISSQVKASRNDIIKALVESEYDVVDAMMKLTK