AbaA

Conidiophore development regulator abaA

943 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity).

Belongs to the TEC1 family.

104.145 kDa

MSSSSSQSSLYQPRPVLSSQRFSPAPDYIDTRRSFHGDSRLPLRESTGNVQQQHHHQEPSSAHSSFNGGSLVGCYQTPVTLSPSMQSSIPPPAPIVPSQSFDCLRSLQATTSRQHHHVPPPLPQVPTRYHQRGKPRNSINPLYFWPAFRQYRNRQAHKDTQKDKGGVWRRPELEDAFVDSVLLMPHMGRRKFSMGGKLHGRNMLISEYIFVICVALLGSKEIFRIDNSNDSIEQMGRKQVSSHMQVVKKFFEDLRCFHFLFPSEEKKEPGTTNSDDFYEEEEQESFKSNPVLTALAEGRVPDVRPNYEYFSQLLALQSSITVRPKTVEIFVSSADVKIRDEVAYDANDNPLDPASFPHLGKYMNSSGDDKPNVLGKDVLLHEYTRSLDRSTSACVKTVTRRWQRDAPAMYDSLDLPDRDEDCLLLEMCSTVDLHEHAKFPSGSELTGYVEVSVTQPALQGHRWKCVTRLTRPPELQTDEGRPEMYSNESGIHRRGCADTRHEDCGCHLRPRQDIHVPFPAVEWASILSMAVQYPDVEHQRKKEKRSCGKKPDLERSASSSKRKRSEDEGDAAAWTRREPTGSDLICKVAMYQELWSCAPDSTRWTRQAIIFWRFSTTNQWYKYNPVFRPAGTTWRWLTVNDPMSRYHQQRALVYPSAGGNNMPRDAVMSPTPSVSQHLTATMSENFSQAWDSSGSNVTTHTQVHVAGGGGGGGSNMTTLFDSFPSGLATPPPTASLHGSYSASGSFDAGNGVGGCYMPPTCGGGADGPHGGLPAPSQSYFDAAGQTVNTTFGDVKPLLSGSATNPYLPGAAGGGGTGSLDLSGQFAYDDGQQHQHQHQHQQHQQQNHNGGSNGGLPGWDMGPALDSWTAGSSAGGAPAATPTGPDWGPTAPVPRMTEHHPGMWDPVHWSNHGTPGRGGEGSPRQMKRRRTEVLVDGVPVTAGW

AbaA

Conidiophore development regulator abaA

885 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation. They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (PubMed:29958281). BrlA, abaA and wetA act together to positively regulate the expression of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).

Belongs to the TEC1 family.

99.498 kDa

MSSLFQPRPVLSSQRYSQSPDYVDTRRSIHNGRLPLRESTGNAQSHSFNGLVSCYQNQVALAPSMQTTIPAPMVPSQSLDCLYRVPTPRQQARFQRRPKTSVNPLYFWPAFRQYRNRQAHKDTQKDKGGVWRRPELEDAFVDSVLLMPHMGRRKFSMGGKLHGRNMLISEYIFVICIALLGSKEIFRIDNSNESIEQMGRKQVSSHMQVVKKFFEDLRCFHFLFPSEEKKEPGSTNSDDCYDEEEQESFKSNPVLTALAEGRVPDVKPNYEYFSQLLALQSSICTRPKTCEIFVSSSDIKIRDDVAYDVHDTPLDQASFPHLNKYTNCDDSPNVLGKDVLLHEYTRSLDRTTSACAKSVTRRWQHDAPAMYETLELPSRDEECLLLEMCATLELHEHAKFPSGSELTGFVEVAITQPALQNHRWKCITRLTRPAELHSDEGKHGVYTNDSGIHRRGCSDSKAECECHTRPRQDIHVPFPAVEWASILSMAVQYPDVEHQRLKEKRRKYADGDGKKELERAGSKRKRSEDEGDAASWTRREPTGSDLICKVAMYQELWSCAPDSTQWTRQAIIFWRFNTTNQWHKYNPVFKPAGTTWRWLTINDPMSRYHQQKALVYPTANVSRDALMSPTPTIHQHLTAAMNETFNSWDQGSSAPHVPHVPPLQTPNNSIGLFDSFSNGLATPPPTATLPPAYPTGNFDSRSGSFDARSASFDTRSGSFDGNLGPNNGVAFLPTTGPPPQHERQPTALGNNNQPFFDGQQSFSEVKPINTAVNSYMTASTSLELPNQLVYDNSGVDTSNMQGWDMSALDGWSAAASAPGSATAEWGPNTKVESHAGDHHGAMWAPPHWPLSAGAAPSSHERGASPRPLKRRRETMDVHVPVTAGW

abaA

Conidiophore development regulator abaA

858 amino acids

AbaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity). Plays a pivotal role in conidiation by regulating cell cycle pathways and other conidiation-related genes (PubMed:24039821).

Belongs to the TEC1 family.

96.444 kDa

MSSSLYHPRPVLSSQRYTPSPDYLQDARRTYHDNSRLPLRETASNAQSHNFNSMVPCYSSQVGISPSVPASLPAPMIPSQSFECLYRVPTPRNQPRFQQRRPRNEVNPLYFWPAFRQYRNRQAHKDTQKDKGGVWRRPELEDAFVDSVLLMPHMGRRKFSMGGKLHGRNMLISEYIFTICVAILGSKEIFRIDNSNDSIEQMGRKQVSSHMQVVKKFFEDLRCFHFLFPAEEKKEPGSTNSDDYYDEEEQESFKSNPVLTALAEGRVPDVKPNYEYFSQLLALQSLISVRPKTAEVYVSSSEVKFRDEIAYDAQDAPLDTESFPHLNKYNNCDDSPSVLGKDVLLHEYTRSLDRTTSACVKTVTRRWQKDAPEIYETLELPTRDEECLLLEMCATLELHEHARFPSGSELTGFVEVAITNPNLQSHRWKCVTRLTRPSELHSDDKKSSVYTNETGIHRRGCSDSKPDCDCHSRPRQDIHVPFPAVEWASILSMAVQYPDVEHQRKKEKRTKGDDRKNLDRAGSKRKRSEDDGDAASWARRDLTGSDLICKVAMYQELWSCAPDSNRWVRQGIVFWRFNTTNQWYKYNPVFKPAGTSWRWLTVNDPMSRYHQQKALVYPSASMSLDSIMSPTPSINQHMTAAMNETFSSAWDPSVSLAQVPNATATNNGLTLFESFSGGLATPPPTAGLQGSYSGSFDHGMPPSTGVGFIPSTCSTAGESHPGTGHGHSHSAAYYDAQTTLADLKPVMSTVNPYQSPTTSSGLDLSSSLVYDNAECDTGLQGWDMPALDGWSTGAGSGSEWGSHHKVEPSSDQTALWTQSQWAQMAGDRDGSPRPMKRRRGDGIDSHIPPTMTAAAGGW

abaA

Conidiophore development regulator abaA

797 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity). Essential for differentiation and functionality of phialides as conidiogenous cells (PubMed:20966095). Regulates autolysis and cell death (PubMed:20966095). Positively regulates expression of the gliotoxin biosynthetic gene cluster in actively growing vegetative cells, and likely bridges morphological and chemical development during the life-cycle (PubMed:26032501). Negatively regulates expression of the melanin biosynthetic gene cluster (PubMed:24123270).

Belongs to the TEC1 family.

88.925 kDa

MATDWQPECIAPQHQSGLENIGHHTDRALQNTSGNVQSYSDAILHGGMSGRDDHLQHLAYKYSHAPVHPQPMQTATTLHPHHILNARVQAKKLRRVQSLGPNHAGARRGRSYLKSQKYLEYRARPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIYKVTGKKRTRKQVSSHLQVLDSFLKGDPDWERLVREQPADRSGNQHQPVGPKWRTSLDHPLPSHYGGHMHATYHDHLSPVQPYVGELPPPHYTLGSNMHERSTDTIHGFNFDMWVSAPQQANQGDKAFHVYTCLQGDQYHPVAPPMPLENVRDWRTTFPHLNSVMEELDGPLDCEIILLEASLKLMNDFPPPGSKLGIQLDIDFAPPGMTDATVLSQMDNWTCSTYIYEDGNRLSKADHNLARPLSTKVKPPFESSWWAKLFTELTQDKQMAEKSGRHQNADDHIRQFFRSLSAVQEIRAISQNSRRVSQGSGHPGDCSKRMAILLWKFRQTLPDEVGLTTWRKLIPPPDRTMMNSPKPATGIDLPPLSLDSILLKPQPPNVYQNPQGHDLLHQNGTSQPHWPLYPPPHESMSNMYHSTGSFDFLNSVSKAEDGLPDRTAVTSILDSFPAMPPQETSQPSSLNVSSGGPVMLNVHDMSLSHHNLAGYALSHDNHYVPSQQHGVSVHDSSNVLNNIFGPGSQPMDEIGNSQSAWGPPIPSTTIPSDVGSNHYTHLPYHHHDHQTSASRESHPPNGFEGLMGPDDLMDKIVGSMPDDPGMNGAGPDHASAAYADTNATEAVQ

abaA

Conidiophore development regulator abaA

796 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:2655931, PubMed:2196567). They act individually and together to regulate their own expression and that of numerous other sporulation-specific gene (PubMed:2655931, PubMed:2823119). Controls temporal and spatial specificity in Aspergillus development (PubMed:2655931, PubMed:7704830). Directs the differentiation of phialides and is continuously required for maintenance of their function (PubMed:2152124). Expression of abaA leads to activation of brlA and wetA, cessation of vegetative growth, and accentuated cellular vacuolization (PubMed:2655931). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (PubMed:8139553). Multiple abaA binding sites are present in the cis-acting regulatory regions of several developmentally controlled structural genes as well as those of the upstream regulatory gene brlA, the downstream regulatory gene wetA, and abaA itself (PubMed:8139553).

Belongs to the TEC1 family.

89.171 kDa

MATDWQPECMVSQNQAALESIGAHSDRALQNTSGNVQAYSDSLAHHDTTGRDDPLQHYTLKYPHPPVPVPSHPLPTATANLYHPQLLSHRYQVKKLRRLQSNGSSYAGSRRGRSYLKSQKYLEYRARPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIYKLTGKRRTRKQVSSHLQVLDSFLKGDPDWERLVREQSDRSTAQTQPVGPRWRTSMDHLPSSHYGTHATSSYPEPMRLMPPYSADLQLPQYSPTSTQQDTNNNTIQGLSFDMWVSAPNKPDRIDDAYHLYTRLQGDQRQPPMPLEDLKNWRVSFPHLSSSLSDVNDPLNCEIILLETNLELMDDFPPMGSRLGIHLELDIANPMSGTAPTVNQMENWTCSTYIYEDGRRTMEAYHNLTKPHTTKVKPPFESSWWAKTFTKLTQDKREAESTGHHHAADERTRRYFHSLTAVQEIRATVPPSLRRLQNHYPGSPAEESKRMAIILWKFRQTRPNEVGTTTWRKLITSPDRALTNSPRPSTAIDLPPLSLDSILLSKPTSNLYQAPPQHHDLLHQNAPSQQSWSLYQPSHDHVNSLYHSAGAFDFLNSITKPEEGLSDKTAPTSVLDPFPNLTQQTTSQTAGINVSSGTPVMLQIPDLSLSSNLGTYGLGHESHYVPSHHNAANLHDHSSTTGLGHYFAPSTQSLDEISHSHAPWSAPNTTISGDTSGGNYHHLPFTTSDHSVTVSRESHQNHSFEGLLPSDDLVGIVGGLSGDPNMNGAGPEHTSSAYAEHTAVEAV

abaA

Conidiophore development regulator abaA

796 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity). Plays an essential role in the differentiation and functionality of phialides (PubMed:25530311).

Belongs to the TEC1 family.

88.403 kDa

MATGWQPECLVTQNQSSLGPVEAHSDRALQNTTGNVQSYSDHLTHADIAAREDQLHQLGFKYPHAPHHPQPLSASGLDQQHVAARLHQRKLRRLHSVGPNSQSRRARSSYLKSQKYLEYRRRPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIFKLTGKRRTRKQVSSHLQVLDSFLKGDPDWERLVREASPERSSSVHGSAPAPKWRTAVEHTSASSHYGSHTHGSYHDHMRSMQPYAGDLPPPHYTLGSNMQEAAASTIHGFNFDMWVTAPQQANRIGKALHTYTRLQGDLHHSAASSMPLEHVNGWRSSFPQLASMVDDINNPMDCDIILLEVNLELMTDFPPARSQLGIQLDLDFGHPSAGDVFGVSQMDNWTCSTHIYEDGQKLIESHDDLPKTQSTKVKPLFESSWWAKMFTKVTQDKRMAEDSGNPQVAREADDNTRNFFRSLSAVQELRATSPSSHRLSNQYQGHHGDESKRMAVLVWKFRQTRPGQVGTTTWRRLIPAPDRTSNNSPLAVSGIDLPPLSLDSILLNKASHQGMYQTPQPHDLIPHPSQSHSQWSLYHPPHDNVANLFNPSGHLDFLASISKAEDTINDKIAVTSVLDSFSTSLAPESIPSTSLHGPSGAPVMLNVHDLPLSHPGIGYAMGHEASHYVPSHQHSVNMHDSNGVLHSFFGSNMQPLDDLSHSHASWGAHSTSIPGDVGAGSYHLSYHPEHHGHGPVSRESQQPHHFDSLLPSEDLMDKIVGRMSNGASMHGAGPDAAGYDNSTVDSV

abaA

Conidiophore development regulator abaA

795 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity).

Belongs to the TEC1 family.

88.428 kDa

MATDWQPECLVTQNQTSLDPVGAHSDRALQNTTGNVQSYSDQLAHADITAREDQLHQLGFKYPHAPHHPQPLSAPGLHQQHVAARLHQRKLRRLHSVGPNSQSRRARSSYLKSQKYLEYRARPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIFKLTGKRRTRKQVSSHLQVLDSFLKGDPDWERLVREASPERSSSVHGSAPAPKWRTAMEHPSASSHYGSHTHPSYHDHMRSMQPYAGDLPPPHYPLGSNMQEAAASAIHGFSFDMWVSAPQQANRLDKALHAYTRLQGDLHHPVAPPMPLEHVSGWRSSFPQLASMVDDINNPLDCDIILLEVNLELMTDFPPAGSRLGIQLDLDYGHPTAGDVLGVSQMDNWTCSTHIYEDSQKILETYHDLPKTQSTKVKPLFESSWWAKLFTQLTQEKRMAEDSGNPQAARDADDHARHFFRSLSAVQELRATPPSSRRLSTQYQGHHGDESKRMAILAWKFRQTRPGEVGTTTWRRLIPAPDRTTTNSPRPVSGVDRPPLSLDSILLNKPSHQGVYQTPQPHDLIHHPSQSHSQWPMYQSPHDNVANLFNTPGHLDFMTSISKAEDGLNDKTAVTSVLDSFSTSLAPESIPSTSLHGPSGAPVMLNVHDLPLSHPGMGYTMGHEASHYVPSQQHSVNMHDSNSVLHGFFGSNTQPLDDLSHGQASWGAHSTSIPGDVGAGSYQLPYQPEHHVPVSRESQQPHHFDGLLPSEDLMDKIVGRMSNGPSIHGAGPDASAGYDNATVDAV

abaA

Conidiophore development regulator abaA

792 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity).

Belongs to the TEC1 family.

88.118 kDa

MATDWQPECLVAQNQPSLDPVGAHSDRALQNTTGNVQSYSDQLAHAGVTARDDQFHQYSFKYPHGPHPQPLSAPGLHQQHVAARLHQRKLRRLHSVGPNSQSRRAQSSYLKSQKYMEYRRRPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIFKLTGKRRTRKQVSSHLQVLDSFLKGDPDWERLVREPALERSSSVHGSAPAPKWRTAVEHPSGSSHYGSHTHPSYHDHMRSMQPYAGDLPPPHYTLGSNMQETAASTIHGFSFDMWVSAPQQANRIDKALHAYTRLQGDLHHPVAPPMPLEHVNGWRSSFPQLASMVDDVNNPLDCDIILLEVNLELMTDFPPTGSRLGIQLDLDYGHPSAGDVLGVSQMDNWTCSTHIYQDSQKLLETYHDLPKTQSTKVKPLFESSWWAKLFTQLTQEKRIAEDSGNPQAARDADDHARQFFRSLSAVQEIRATSPSSCRLSNQYQGHHGDESKRMAVLAWKFRQTRPGEVGTTTWRRLIPAPDRTTTNSPRPASAVDRVPLSLDSILLNKPSHQGIYQAPHPHDLIHHPSQSQSQWPMYQSPHDNVSNLYNPSGHLDFMSSISKAEDGLNDKIAVTSVLDSFSASLAPESISSTSLHGSSGAPVMLNVHDLPLTHPGMGYTMGHETSHYVPSQHHSVNMHDSNSVLHGFFGSHTQPLDDLSHGHGSWGTHSTSIPGDVGAGSYHIPYQAEHHGPVSRESQQPHQFDGLLPSEDLMDKIVGRMSNGSGMHGAGPDAGYDNATVDAV

abaA

Conidiophore development regulator abaA

785 amino acids

BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:19850144). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity). Controls expression of wetA (PubMed:19850144).

Belongs to the TEC1 family.

88.24 kDa

MAEWQTECMLPPTQPGFEGVGPHPGRVLQNTSGNIQSYSDTLAHTDPTGRDDHFSHYGFKYPHQPPVPTHPMPTTTGLHPQQVINNRFHTKKLRRLQSLGPNLIGPRRTRSYLKSQKYIEYRARPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIYKTTGKRRSRKQVSSHLQVLDSFLKGDPDWERLVREQPADRSNGQPPSAGPRWRNSLELPFSSHYNSHNYPSYHDSLRPVQSYSGELPPPHVVFHPNLHAEATNINKIYGLSFDMWVSAPNQPGGIESAFHLYTRLQGDQRHPAPPKRLENIPNWRTSFPHLNSVMADVNNPLNCDIILLEANLRLMDDFPPSGSKLGIQLELDFTQPPNGDALTNQMENWSCSTYIYEEGQNIYRARQDLPKQQSNKVKPPFESTWWAKRFTELTEIAKDRQLNELADRQTRDYFRTLTAVQEIRATPSSRRVSNQYPDNSQDDSKRMAILLWQFRQTRSNEVGTTTWRRVTSPSSDRNTIPSPKPVTGIDLPPLSFYANSLARPAPSIYQAPQSHDLVHHNGTSQPQWSMYQPPQDSIFNANGGFDLLNSITKPEGGLHDKTAVTSVLDTYPNLQPEVSQPTSLNGSNGGPGMLSIPDMSLSHTNLNAYNLSGHDNHYGTPQHPGVSVPDNSHVLNNGIFGSSTQSIDDMSQTHAPWPTPTSSITDVGSSNYSHLQFSDHHVPSVSRESHQPNHFEVLLGPDDLIVGSMPGDPGINGAAHGHMNHTYTENNAVEAA