BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation. They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (PubMed:29958281). BrlA, abaA and wetA act together to positively regulate the expression of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).

Belongs to the TEC1 family.

885 amino acids

MSSLFQPRPVLSSQRYSQSPDYVDTRRSIHNGRLPLRESTGNAQSHSFNGLVSCYQNQVALAPSMQTTIPAPMVPSQSLDCLYRVPTPRQQARFQRRPKTSVNPLYFWPAFRQYRNRQAHKDTQKDKGGVWRRPELEDAFVDSVLLMPHMGRRKFSMGGKLHGRNMLISEYIFVICIALLGSKEIFRIDNSNESIEQMGRKQVSSHMQVVKKFFEDLRCFHFLFPSEEKKEPGSTNSDDCYDEEEQESFKSNPVLTALAEGRVPDVKPNYEYFSQLLALQSSICTRPKTCEIFVSSSDIKIRDDVAYDVHDTPLDQASFPHLNKYTNCDDSPNVLGKDVLLHEYTRSLDRTTSACAKSVTRRWQHDAPAMYETLELPSRDEECLLLEMCATLELHEHAKFPSGSELTGFVEVAITQPALQNHRWKCITRLTRPAELHSDEGKHGVYTNDSGIHRRGCSDSKAECECHTRPRQDIHVPFPAVEWASILSMAVQYPDVEHQRLKEKRRKYADGDGKKELERAGSKRKRSEDEGDAASWTRREPTGSDLICKVAMYQELWSCAPDSTQWTRQAIIFWRFNTTNQWHKYNPVFKPAGTTWRWLTINDPMSRYHQQKALVYPTANVSRDALMSPTPTIHQHLTAAMNETFNSWDQGSSAPHVPHVPPLQTPNNSIGLFDSFSNGLATPPPTATLPPAYPTGNFDSRSGSFDARSASFDTRSGSFDGNLGPNNGVAFLPTTGPPPQHERQPTALGNNNQPFFDGQQSFSEVKPINTAVNSYMTASTSLELPNQLVYDNSGVDTSNMQGWDMSALDGWSAAASAPGSATAEWGPNTKVESHAGDHHGAMWAPPHWPLSAGAAPSSHERGASPRPLKRRRETMDVHVPVTAGW

99.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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