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zip-10

Gene
zip-10
Protein
Transcription factor zip-10
Organism
Caenorhabditis elegans
Length
165 amino acids
Function
Transcription factor that regulates the expression of genes in response to changes in temperature. In particular, binds to the promoter region of genes such as asp-17 in response to severe cold to warm temperature transitions to promote gene expression. Promotes stress-induced death, particularly in older animals, following cold shock followed by warming and this may have evolved as a form of kin survival under thermal stress conditions, favoring the survival of younger animals.
Mass
18.288 kDa
Sequence
MTTMTNSLISNSVSSVPESLFSSASIHRPVAINPAMLAQFSINLPVLPFESSASLGTSTTSSSRCSSTESSAAPGKIRRGRPQQEIADGQDAHSQKKRHRRLYARQYRAQMRQKVENVKSLHDEKEQLELEVKALRQAVSGLQQENAQKDFLISILQLNNQINHS