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selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Nitrosomonas eutropha (strain DSM 101675 / C91)
Length
388 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
44.008 kDa
Sequence
MNNPNIDSDELTALFTADTPLIDVRAPLEFILGSLPGSVNLPILNNEERALVGTTYKQQGSEAAVMLGHEMISGQAKQDRLQQWLDFIRQHPRTVLYCFRGGKRSQITQQWLKDAGVDRPLIIGGYKQARQFLINTIDRFSENHTLLVITGPTGSGKTQLIQEIRNSYPVLDIEALARHRGSAFGGMSLPQPTQIDFENQLAVNLLKLKQNYLFDPVVVEDESRHTGRVYLPASFFEHMRSSEIIWVDEPLNTRVDNIFGDYIVATPIGQAQQARRNTQPLSSATEIQEILCQQALLLFDKYASALQAISKKLGGVRFQEVSQDLENARSSFVNRNEIQSNKTWIEKLVRYYYDPLYLGSLQRRQVNPCFKGSRQAAIDYLRARKQHA
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Length
385 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
43.72 kDa
Sequence
MRNPDIGIDDLTALFIADTPLIDVRAPVEFTQGSLPGAVNLPILNDEERALVGTTYKQQGSEAAIKLGYEMVSGSVKQNRLQQWLDFIHQHPRAILYCFRGGKRSQITQQWLRDTGIDSPLITGGYKRARQFLISTIDRFSEHRKLLVITGPTGSGKTRLIHDISNSHPVLDIEALARHRGSAFGGMSVPQPSQIDFENHLAVNLLKLEQNNLSEPVIVEDESRHTGKVYLPDSFFHHLRNSEIIWVDEPLATRVDNIFEDYILTTPIGQAQRIRQAIPPLASTVETREILRQQARQLFDKYAGALQAISKKLGGDRFQEVSEDLENARSDFENKNEIQSNKIWIEKLVRYYYDPLYLGSLQRRRVNPCFKGSGQAVMDYLQARK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella sp. (strain MR-4)
Length
384 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
43.684 kDa
Sequence
MTTKLIPAQQYHDIFVAGKPLIDLRAPIEFDRGAFPSSVNLPLMVDKEREKVGTCYKEQGQQAAIALGHSLVHGVVKQQRIDAWLNFLSAHPQAYLYCFRGGLRSQLTQQWLQEAGVTVPYVQGGYKGMRQYLIGVIEAAPSLQPLLSLSGMTGSGKTDFLKRRKEAIDLEGIANHRGSSFGKNIDPQPTQINFENRLAIALLHHQLGNHACLLLEDESFLIGRSALPQSFYSAMQTADIVVLEEDDDIRLTRLLDEYVHKMHRGFIERLGLEAGFEAFSHYLLQSLGSIRKRLGGKQYQELQDIMQQALSQQLNQNQTSQHLAWISLLLHKYYDPMYEYQLQKKAGNILFRGSHQATHEWLDNYQRDNYHRNNDPLNSQHSKG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Hahella chejuensis (strain KCTC 2396)
Length
379 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
43.09 kDa
Sequence
MKAFGDGQDTEDYLNLFLSGAPLLDTRAPVEFHKGAFPGAVNLPLMTDDERAQVGRCYKRHGQQAAIELGHRLAHGAVKESRVQGWREFAQRHPQGYLYCFRGGLRSSICQQWLAESGVAYPRVLGGYKAMRRFLIESLESICQEARLVLLAGHTGGGKTDLLARIPGAVDLERLAHHRGSAFGRRADGQPSQIDFENALAVALLRQRHGFANAPLLLEDESHLIGRCALPQSLRRAMAQAPLVVVEVALEQRVEHSFRNYILHKLDEWRRRQGEDEGFERFADDLRQSMYNIRTRLGGLRYQQLSEMLEAALARHRQGDPAYHRDWIRCLLEDYYDPMYAYQLQKRAERICFRGDAAAVRDYFAHSSSTTATVRDKRL
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
Length
379 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.791 kDa
Sequence
MSLKNIKPDQLKNLFQQNIPLMDVRAPVEFSQGSIPGAVNLPVMNDDERAQVGTVYKNQGNEAAVKLGHELVSGLVKEQRVAAWKSFVQAHPEAVFYCFRGGQRSRISQAWLKEAGVERPLLVGGFKAARNYLIKQIEEFSVRQELISVSGPTGSGKTHFLRGLKGCPVIDLEALARHRGSAFGNWEVPQPTQVDYENNLAREILLLEDKIHGKIKPLVEDESRLIGRISQPATFFIRLRSSPVIWIDEPLPVRVDNVFDDYILNSSIGKSLEAAPRCAEENDILRAQALQLFARYRQSLLAIQRKLGGLRAQEVMADLEKAELAYLNHAELSGNKVWIEKLLQYYYDPMYLGSLERRHVTVLFKGTRFEAEKFVHSLT
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Cronobacter sakazakii (strain ATCC BAA-894)
Length
377 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.608 kDa
Sequence
MQKDAQRRPDSDDALALITRGVTLIDVRAPVEFAQGAMPGAINLPLMNNDERAAVGTCYKQHGQQAALALGHRLVYGEVREARLNAWRLACERHPEGFLCCARGGMRSYIVQQWLRERGIDYPLVEGGYKRLRQEAMDATDRLSRLPMVLIGGCTGSGKTQLVKALPTGIDLEGLAHHRGSSFGRTLTPQRAQASFENHLAAAMLNHHARWTTLSNPFWVLEDEGKMIGANHLPAVLREQMLQAPVAVVEEPLERRLERLREEYFVQMQAAFQAALGDEAAGWRAYGDYLHHGLYAIRRRLGLARYAELAALQEAALARQQRTGETHAHFAWLAPLLEGYYDPMYRYQLEKKAQQIAFRGDYHQVDAWLRHRYCASR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella oneidensis (strain MR-1)
Length
376 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.611 kDa
Sequence
MTTTLIPAQQYRDIFVAGKPLIDLRAPIEFNRGAFPSSVNLPLMVDKEREKVGTCYKQQGQQAAIALGHSLVHGAVKQQRIDAWLGFLAAQPEAYLYCFRGGLRSQLTQQWLKEAGATVPYVQGGYKGMRQYLIGVIETTPSQQPLLSLSGMTGSGKTDFLIQRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLRHQQDNHSCLLLEDESFLIGRSALPQSFYNAMQAADILVLEEADDIRLNRLLDEYVHKMHQGFVERLGIEAGFNAFSQYLLQSLTSIRKRLGGKQYQELQDTMQQALSQQLNQNQTSQHLAWINLLLQKYYDPMYEYQLEKKAHRVLFRGNHQAMHEWLDNLSQDSLSQENLG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)
Length
374 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.114 kDa
Sequence
MRADTNNYRELFLRDVPMLDTRAPTEFSKGAFPGAVNLPLMDDAERQQVGLCYKQRGQDAAIALGHQLVSGPIKARRVAAWADFARAHPDGYLYCFRGGLRSQISQAWLKNEAGIEYPRVIGGYKAMRGFLLQTIDDAVAQCGFVVLGGMTGTGKTDLLRQLDNSLDLEHHAHHRGSSFGKHAVGQPTQIDFDNRLAIDILKKRAAGHDRFVLEDESQAIGACSLPFELYRGMQEYPVVWLEDTTENRVNRILRDYVIDLCAEFVDVHGPEQGFDRFAERLRQSLDNISRRLGGERHRQLAGVMDAALAEQQRSGRVDAHRAWIAALLAQYYDPMYAYQRQRKSQRIVFAGDHQSVLQYLRDPPAVGRALKGFP
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas mendocina (strain ymp)
Length
373 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.815 kDa
Sequence
MRENCTDYRDLFINDRPMMDARAPVEFHKGAFPGVINLPLMNDIERQKVGTCYKQHGQQAAIELGHQLVSGRTKAERIEAWASFAKANPDGYLYCFRGGLRSQIVQQWLKSEAGIDYPRVIGGYKAMRGFLLETTEQAVAECDFVLVGGMTGTGKTEVLAQLHNAVDLEAHANHRGSSFGKRASGQPAQIDFENALAIDLLKRRAAGQRQFVLEDEARLIGRCSLPLPLYQGMQHYPLVWLEDSLGDRVERILQAYVVELCAEFVAVEGAEAGFAAFAARLRESLANITRRLGGERYQRLAAIMDQALEEQARDGQVDTHRGWIEALLVEYYDPMYVFQRESKAGRIEFAGEQQAVVEYLRQRSGHFPEAPAS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Serratia proteamaculans (strain 568)
Length
372 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.738 kDa
Sequence
MSATREREDGQDYRRIFLQDIPLIDVRAPVEFQQGAFANAVNLPLMNDDERQAVGTCYKQQGQQAAIALGHSLVNGRLREQRTAAWLAQCAQWPEGYIYCFRGGLRSQLVQQWLREAGVAYPRITGGYKALRNFLLTTLEQSAELPMVLIGGNTGSGKTLLVNELADGVDLEGAAHHRGSSFGRTLVSQSGQIDFENRLAVLLLKKQHGGCRRWVLEDEGRIIGSNNLPLPVFNRMQQAPVAVIDDPFEVRLARLQHEYIDRMRIEFEQAYGAQLGWQKYDEYLHHGLFAIRRRLGLERFQLLTQHLERALQYQQASGNSDEHQQWLVPLLQHYYDPMYHYQLEKKSQRIVFRGNYAEVREFLMTYSQNNGE
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Length
372 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.927 kDa
Sequence
MDNHQLANVIPASEYGRILASGHPIMDVRAPIEFTKGAFPASSNHPLMRDDERQQVGTCYKEHGQDAAIALGHSLVCGAVKQQRVDAWLAYLDAHPDAYLYCFRGGLRSQLTQQWLAEAGRDVPYIQGGYKAMRQYLIDTIDRAPEARPMLILSGITGSGKTDFLLQRQEAVDLEGLAHHRGSSFGRYHEGQPTQINFENSLGVALLKHQQSPARILLLEDESYLIGRSALPKAFYMGMQAASVVILEEPLEARLTRLLDEYVHKMHRGYVERLGEEAGFEAFAEYLANSISGIKKRLGGKQHDELQQMITDALAVQTQRGDTQAHLEWIALLLSKYYDPMYQYQIGKKADRVIFQGDHQAMHQWLDEYATR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
Length
372 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.095 kDa
Sequence
MSINTSGKITSATERADSADFRTIIRNKIPLMDVRAPVEFGKGAFDLSINYPLMNNDERADVGICYKQNGQEAAIKLGNALVSGQSKARRLTQWQTFARENPQGYLYCFRGGLRSQTVQRWLKESGINYPLITGGYKALRQFLLNELEQLALHPLTILAGNTGSGKTPFLAHCANSLDLEGAAGHRGSSFGSFVTPQSNQINFENKLAEQYIRGDFSLEQRLVLEDEGRLIGSVHLPESLRNAMTLAPLVVIEESLEYRLEQIYQEYIIKMTAQYQAAYGVEQGFTAFSEYLEHGLFKVRKRLGTQRYGQLKEIQSTALTQQNKGQPQYHLDWLKPLLSEYYDPMYQYQLGLKSDRVIFRGNNSECLAFLRD
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas entomophila (strain L48)
Length
371 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.904 kDa
Sequence
MRPDCTDFNTLFLDDVPMMDMRAPIEFTKGAFPGVVNLPLMNDQERQKVGTCFKQQGQSAAIALGHQLVNGALKQQRLEAWAAFAQAHPDGYLYCFRGGLRSQIVQGWLKEAGIQYPKVVGGYKAMRTFLLDTTQQAVEQCDFVLLGGLTGTGKTDVLQQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENGLAIDMLKKRARGIGQFVLEDEGRIVGSCTVPLGLYQGMQRYPLVWLEDAFDNRVERILRDYVTNLCAEFVAVHGEEDGRRLFAERMRQSMANIYKRLGGERFQRLSELLGQALDEQLRSGDVSLHRGWIEGLLKEYYDPMYAYQREAKAGRIEFAGDGVEVREYLKARARRQHRVDL
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Aeromonas salmonicida (strain A449)
Length
371 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.929 kDa
Sequence
MSQLPLTSDLARIFLDDVPLIDLRAPIEFKEGAFPCSTSLPLMTDDERAQVGTCFKQRGQAAAIELGHQLVGGAVRAERLDGWLAQLRKQPDALLYCFRGGLRSQTVQLWLHEAGVTRPRVAGGYKEMRRFLIDTLDKAAAECHWTVLTGMTGSGKTHMLEHVTQAVDLEGHAHHRGSSFGQLPGGQPSNINFENKLAIELLKRRHQGEHAFVVEDESRLIGRCCLPNPLFDAMCEAPLVVVDVPQSERAEQIRQDYVHDLWLRYQAMFGAEEGWPLFAAYLTDALARLKRRLGDQAHRELDQLMQIALAEQANSGTTERHLAWITLLLTRYYDPMYLYQLGNKRERIVFRGEKQACLDFFAEQHAARQQG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
370 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.897 kDa
Sequence
MRPDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMNDQERQKVGTCYKQQGQAAAIALGHQLVSGATKQARLEAWAAFAKAHPDGYLYCFRGGLRSQIVQGWLRDEAGIQYPRVKGGYKAMRTFLLETTQQAVEQCDFVLVGGLTGTGKTDVLHQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENQLAIDVLKKRARGIGQFVLEDEGRIVGSCTVPLELYQGMQHYPLVWLEDSFTNRVERILRDYVVNLSAEFKAVHGEEDGPRLFAERMLQSMANIYKRLGGERHQRLSEMLREALQEQQRSGAVDLHRGWIEGLLNEYYDPMYAYQRAAKAERIEFAGDAVEVREYLKARALRQPRK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Length
370 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.928 kDa
Sequence
MRPDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMNDQERQKVGTCYKQQGQAAAIALGHQLVSGTTKQARLEAWAAFAKAHPDGYLYCFRGGLRSQIVQGWLRDEAGIQYPRVKGGYKAMRTFLLETTQQAVEQCDFVLVGGLTGTGKTDVLHQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENQLAIDVLKKRARGIGQFVLEDEGRIVGSCTVPLELYQGMQHYPLVWLEDSFTNRVERILRDYVVNLSAEFKAVHGEEDGPRLFAERMLQSMANIYKRLGGERHQRLSEMLREALQEQQRSGAVDLHRGWIEGLLNEYYDPMYAYQRAAKAERIEFAGDAVEVREYLKARALREPRK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas putida (strain GB-1)
Length
370 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.028 kDa
Sequence
MRPDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMNDQERQKVGTCYKQQGQAAAIALGHQLVSGTTKQARMDAWVAFTQANPQGYLYCFRGGLRSQIVQGWLRDEAGIQYPRVKGGYKAMRTFLLETTQQAVAQCDFVLLGGLTGTGKTDVLHQLDNVLDLEGHANHRGSSFGKRATAQPAQIDFENQLAIDVLKKRARGCEQFVLEDEGRIVGSCTVPLELYQGMQQYPLVWLEDSFANRVERILRDYVVNLSAEFIAVHGEEDGRRLFAERMLQSMANIYKRLGGERYQRLSEILRLALEEQQRSGAVDLHRGWIEGLLNEYYDPMYAYQRAAKAERIEFAGDAVEVREYLKARARRQPHH
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Length
370 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.177 kDa
Sequence
MRADTADYPQLFLEDVPMMDTRAPVEFAGGAFPNVLNLPLMTDSERQKVGTCYKQHGQRAAIELGHRLVSGRTKELRIQAWADFARAHPEGYLYCFRGGLRSQIVQQWLRDEAGIDYPRVTGGYKAMRNFLLDTTRQATAQCAFVLVGGLTGTGKTEVIAALGNALDLEGHANHRGSSFGKRATPQPAQIDFENRLAIDILRKRAAGVGRFVLEDESRLVGSCSLPLELHQGMQRYPLVWLEDSFEGRVERILRDYVVDLCAEFVAVEGPQAGFAAFAARLTQSLANIVKRLGGERYQRLSTLMARALAEQEAGRGVALHRDWIVGLLREYYDPMYAYQRESKAERIVFSGDREAVLAYLRECAAGAVDG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas aeruginosa (strain PA7)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.784 kDa
Sequence
MRDNTQHYRELFLEDTPLMDVRAPVEYHKGAFPHTVNRPLMNDIERQKVGTSYKQHGQQAAIALGHELVCGAVKAERLAAWKAFAEANPNGYLYCFRGGLRSQIVQQWLKQDAGIDYPRVIGGYKALRNFLFETTRAAVDECDFVLVGGLTGCGKTEVIAALDNSLDLEGHANHRGSSFGRRATPQPAQIDFENRLAIDILKKRHRGVGQFVLEDEGRIVGSCSLPLELYQGMQGYPLVWLEDGFEQRVARILKDYVIDLRSEFERVVGAEEGFAVFSAYLQKSLAGIVKRLGGERYQRLAAILVQALEEQGRDGSVETHRGWIEGLLKEYYDPMYAFQRQSKEDRVEFRGNQAEVIAYLRQRQALRPS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas aeruginosa (strain LESB58)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.875 kDa
Sequence
MRDNTQHYRELFLDDIPLMDVRAPVEYHKGAFPNTVNRPLMNDIERQKVGTSYKQHGQQAAIALGHELVCGALKAERLAAWKAFAEANPNGYLYCFRGGLRSQIVQQWLKQDAGIDYPRVIGGYKALRNFLFETTRAAVDECDFVLVGGLTGCGKTEVIAALDNSLDLEGHANHRGSSFGRRATPQPAQIDFENRLAIDILKKRHRGVGQFVLEDEGRIVGSCSLPLELYQGMQSYPLVWLEDAFEQRVERILRDYVIDLRSEFERVVGVEEGFAAFSAYLQKSLAGIVKRLGGERYQRLAAILVQALEEQGRDGSVDTHRGWIEGLLKEYYDPMYAFQRQSKEDRVEFRGNQAEVIGYLRQRQALRPS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.845 kDa
Sequence
MRDNTQHYRELFLDDIPLMDVRAPVEYHKGAFPNTVNRPLMNDIERQKVGTSYKQHGQQAAIALGHELVCGALKAERLAAWKAFAEANPNGYLYCFRGGLRSQIVQQWLKQDAGIDYPRVIGGYKALRNFLFETTRAAVDECDFVLVGGLTGCGKTEVIAALDNSLDLEGHANHRGSSFGRRATPQPAQIDFENRLAIDILKKRHRGVGQFVLEDEGRIVGSCSLPLELYQGMQGYPLVWLEDAFEQRVERILRDYVIDLRSEFERVVGVEEGFAAFSAYLQKSLAGIVKRLGGERYQRLAAILVQALEEQGRDGSVDTHRGWIEGLLKEYYDPMYAFQRQSKEDRVEFRGNQAEVIGYLRQRQALRPS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.845 kDa
Sequence
MRDNTQHYRELFLDDIPLMDVRAPVEYHKGAFPNTVNRPLMNDIERQKVGTSYKQHGQQAAIALGHELVCGALKAERLAAWKAFAEANPNGYLYCFRGGLRSQIVQQWLKQDAGIDYPRVIGGYKALRNFLFETTRAAVDECDFVLVGGLTGCGKTEVIAALDNSLDLEGHANHRGSSFGRRATPQPAQIDFENRLAIDILKKRHRGVGQFVLEDEGRIVGSCSLPLELYQGMQGYPLVWLEDAFEQRVERILRDYVIDLRSEFERVVGVEEGFAAFSAYLQKSLAGIVKRLGGERYQRLAAILVQALEEQGRDGSVDTHRGWIEGLLKEYYDPMYAFQRQSKEDRVEFRGNQAEVIGYLRQRQALRPS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.144 kDa
Sequence
MPSAIVAAEQYREIFLNQHPMMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQFGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPNAYLYCFRGGLRSQLTQQWLKEAGIEVPYIQGGYKAMRQYLIGVIEAAPTQQPLLSLSGMTGCGKTDFLLQRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLRHQQDNHSCLLLEDESFLIGRSALPQSFYSAMQAAEILVLEEPDDTRLKRLRNEYVHKMYSGFCERLGLEAGFAAFSEYLLQSLMSIRKRLGGKQHQELQDLMQQALNQQISQNDTSLHLVWIHLLLHKYYDPMYQYQLQKKSERVLFKGSHQAMHEWLNNFKSTQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella sediminis (strain HAW-EB3)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.996 kDa
Sequence
MSQNIVPKSAYREIMLSGHPMMDVRAPIEFNKGAFPSSTNLPLMQDSERQKVGTCYKNKGQDAAIALGHSLVNGQIKQQRVEAWLEFISLHPNAYLYCFRGGLRSQLTQQWIKEAGIEIPYVEGGYKAMRQYLIEVIDEAPKQSPIHILSGITGSGKTDFLLQRSEAIDLEGLAHHRGSSFGRYHEPQPSQINFENNLAVSLLKHQERAEKCLLVEDESFLIGRSAIPKQFYSGMQAADMLVLEEPEGARLNRLLNEYVHKMHSGYVERLGEEAGFDAFAEYLSQSITGIKKRLGGQLHDEFQSIIANALNIQRQRGDTQPHMEWISLLLTKYYDPMYQYQLDKKQSRVIFKGSHQAMHEWLDEYSSKG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella sp. (strain MR-7)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.936 kDa
Sequence
MTTKLIPAQQYHDIFIAGQPLIDLRAPIEFDRGAFPSSVNLPLMVDKEREKVGTCYKEQGQQAAIALGHSLVHGVVKQQRIDAWLNFLSAHPQAYLYCFRGGLRSQLTQQWLQEAGVTVPYVQGGYKGMRQYLIGVIEAAPSLQPLLSLSGMTGSGKTDFLKRRKEAIDLEGIANHRGSSFGKNIDPQPTQINFENRLAIALLHHQLGNHACLLLEDESFLIGRSALPQSFYSAMQTADIVVLEEDDDIRLTRLLDEYVHKMHRGFIERLGLEAGFEAFSHYLLQSLGSIRKRLGGKQYQELQDIMQQALSQQLNQNQTSQHLAWISLLLHKYYDPMYEYQLQKKAGNILFRGSHQATHEWLDNYQSER
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella sp. (strain W3-18-1)
Length
369 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.144 kDa
Sequence
MPSAIVAAEQYREIFLNQHPMMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQFGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPNAYLYCFRGGLRSQLTQQWLKEAGIEVPYIQGGYKAMRQYLIGVIEAAPTQQPLLSLSGMTGCGKTDFLLQRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLRHQQDNHSCLLLEDESFLIGRSALPQSFYSAMQAAEILVLEEPDDTRLKRLRNEYVHKMYSGFCERLGLEAGFAAFSEYLLQSLMSIRKRLGGKQHQELQDLMQQALNQQISQNDTSLHLVWIHLLLHKYYDPMYQYQLQKKSERVLFKGSHQAMHEWLNNFKSTQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.658 kDa
Sequence
MRPDTSDFRELFLSGVAMLDVRAPLEFARGAFPGAVNLPLMDDAERHEVGLCYAQKGQQAAIELGHELVSGQRKAARIAAWAEFARAHPDGYLYCFRGGLRSQLVQQWLRDAGVDYPRVSGGYKAMRGFLIETIDTAAATQPWFVVGGLTGSGKTDVLADVPASIDLEGHARHRGSAFGRRALPQPPQIDFENALAIDVLHHLDAGWRALVVEDEGRFIGSRDVPQALSQRMQASPLVWLEAPFNARVERVLRDYVQGLAAEFIDTKGSAEGFAAYATRLREAMAAIAPRLGGARYGKLAALLDQALARQAESGEVALHRGWIEVLLRDYYDPMYDYQRAQREARIVFRGDRDAVTDWLLAHTARQGE
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella baltica (strain OS223)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.75 kDa
Sequence
MPNAIVAAEQYREIFLNQHPIMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQSGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPNAYLYCFRGGLRSQLTQQWLKEACVEVPYIQGGYKALRQYLIGVIEAAPTQQPLLSLSGMTGCGKTDFLLQRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLQHQTSDAACLLLEDESFLIGRSALPQTFYNAMQAANVLVLEESDDARLERLRNEYVHKMYSGFCERLGAEAGFAAFSDYLLQSLVSIRKRLGGKQHQELQDLMQQALDQQINQNDTSLHLVWINLLLHKYYDPMYLYQLEKKSERVLFKGSHQAMHEWLDSYQTR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella baltica (strain OS155 / ATCC BAA-1091)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.679 kDa
Sequence
MPNAIVAAEQYREIFLNQHPIMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQSGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPNAYLYCFRGGLRSQLSQQWLKEAGVEVPYIQGGYKAMRQYLIGVIEAAPAQQPLLSLSGMTGCGKTDFLLQRKEAVDLEGIANHRGSSFGKNIDPQSTQINFENQLAIALLQHQTSDAACLLLEDESFLIGRSALPQTFYNAMQAANVLVLEESDDARLERLRNEYVHKMYSGFCERLGPEAGFAAFSDYLLQSLVSIRKRLGGKQHQELQDLMQQALDQQINQNDTSLHLVWINLLLHKYYDPMYLYQLENKSERVLFKGSHQAMHEWLDSYQTR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella baltica (strain OS185)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.746 kDa
Sequence
MPNAIVAAEQYREIFLNQHPIMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQSGQQAAIALGHSLVNGPIKQQRIEAWTSYVKANPNAYLYCFRGGLRSQLTQQWLKEAGVEVPYIQGGYKAMRQYLIGVIEAAPIQQPLLSLSGMTGCGKTDFLLQRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLQHQTSGVACLLLEDESFLIGRSALPQTFYNAMQAANVLVLEESDDARLERLRNEYVHKMYSGFCERLGPEAGFAAFSDYLLQSLVSIRKRLGGKQHQELQDLMQQALDQQINQNDTSLHLVWINLLLHKYYDPMYLYQLDKKSERVLFKGSHQAMHEWLDSYQTR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella baltica (strain OS195)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.675 kDa
Sequence
MPNAIVAAEQYREIFLNQHPIMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQSGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPKAYLYCFRGGLRSQLTQQWLKEAGVEVPYIQGGYKAMRQYLIGVIEAAPAQQPLLSLSGMTGCGKTDFLLLRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLQHQTSGVACLLLEDESFLIGRSALPQTFYNAMQAANVLVLEESDDVRLERLRDEYVHKMYSGFCERLGAEAGFAAFSDYLLQSLVSIRKRLGGKQHQELQDLMQQALDQQINQNDTSLHLVWINLLLHKYYDPMYLYQLQNKSERVLFKGSHQAMHEWLDSYQTR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella woodyi (strain ATCC 51908 / MS32)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
42.369 kDa
Sequence
MSRNIIPKTTYQEIMLSGHPMIDVRAPIEFDKGAFPSSSNFPLMQDSERQRVGTCYKEQGQDAAIALGHSLVNGKVKQQRVDAWLAFIKQHPDAYLYCFRGGLRSQLSQQWIKEAGVDIPYVEGGYKAMRQYLIEVIDNAPAKQPVFILSGITGSGKTDFLLQRSEAVDLEGYAHHRGSSFGRYHEGQPTQINFENQLAVALLKHQERKEQCLLVEDESFLIGRSAIPKAFYEGMQNADILVLEEPEETRLTRLLNEYVHKMHSGYVERLGEEAGFTAFSEYLSQSITSIKKRLGSQLHDEFQTIISKALNMQLQQNDTQGHLEWISLLLTRYYDPMYQYQLEQKQERVIFKGSHQAMHEWLDHYRNR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
368 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.681 kDa
Sequence
MRADTRDFRALFLGDAPLLDTRAPVEFAKGAFPGAVNLPLMSDAERHKVGLCYKQQGQDAAIALGHRLVSGAVKAERVAAWAAFAQAHPEGYLYCFRGGLRSQISQAWLREEAGIAYPRVIGGYKAMRGFLLETIEQAIAECGFVVLGGMTGTGKTDVLRQLDHGLDLEAHAHHRGSSFGKHATGQPAQIDFDNRLAIDILKKRAAGCRQFVVEDESQAIGSCSLPFGLYQGMQRYPVVWLEDTQPARVQRILRDYVIDLCGEFTALHGEQDGFGLYAARLRQSLDNIARRLGGERHRRLAALMDEALARQAGDGSVDAHRAWIEPLLTEYYDPMYAYQRQAKAARIVFTGDHQEVLDYLRGPGRALP
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Length
367 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.715 kDa
Sequence
MASRPDTDDYLNLFLNDVPLMDVRAPVEFAKGSFPSAENAPLMNDEERHRVGICYKEKGQDKAIELGHQLVSGDIKAQRIEAWKRFVAQHPEGYLFCFRGGLRSRLTQQWIRDSGIDYPLVKGGYKALRRFLIDSLEAQIESGQFRILSGRTGTGKTRVLMQLPNPVDLEGLANHRGSSFGRQVTPQPSQIDFENRLGVAMLKARHQAGGPIYLEDESRLIGRCALPETLRARMSESPLLILEQAMEERIAIIRADYVEGMLASYRARDGEDAGWLNFRDYLLSAIDRIRKRLGGERYQKLRNLMLQALDQQEANGSLEGHHGWIEALLTDYYDPMYDYQLTQKQGEILVRGGPEVITEWARSRTST
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
367 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.758 kDa
Sequence
MSIDVTDYRDIFLNDRPLMDARAPVEFHKGAFPGAVNLPLMNDIERQRVGTCYKHHGQQAAIELGHQLVSGPVKEERIQAWAEFARTHPEGYLYCFRGGLRSQIVQQWLKSEAGVDYPRIGGGYKALRGFLIDTLESALTDCDFVLLGGMTGTGKTEVLAQLRNSVDLEGHANHRGSSFGKRATGQPSNIDFENRLAIDLLKKRAAGIDQFVLEDESRVVGSCALPLPLYQGMQQYPMVWLEDRFEQRVERILRDYVVDLSAEFQAVHGEEGFGRFCERLLESLDNVHKRLGGERHRRMRVLMEEALAEQGRSGAVELHRAWIEGLLREYYDPMYVFQREKKGGRIEFAGERQAVIEYLRQRGKSQA
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Length
367 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.726 kDa
Sequence
MSTNTVPAKQYREIFLKGHPIMDVRAPIEFSKGAFPNAVNLPLMTDSERQKVGTCYKEHGQEAAIELGHQLVAGKVKANRVDAWKAFFSEHPDGFLYCFRGGLRSRITQSWLKEVGLDIPFIEGGYKAMRQFLIDEIDTAPGKSEMLILSGITGSGKTDFVRLRSESVDLEGIANHRGSSFGRQHEGQPSQIDFENRLAIELLRHQEREQAKLLLEDESFLIGRNAIPKTFFEKMQQAPVLVLTSTLEERLPRLLDDYVHKMHAGYVERLGEEQGFIAYRDYLLGSLKGIYKRLGGKLHAEMTELMNKALATEQSRRDTSAHLDWISLLLESYYDPMYHYQLGKKAARVRFTGTHAEMHEYLSSLGK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Length
367 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.584 kDa
Sequence
MTRQIIPSSEFASLFLQARPLIDVRAPIEFTKGAFPSAINLPLMKDSEREKVGTCYKQQGQESAIKLGHALVSGTVKEQRIAAWRKAIEANPSSYLYCFRGGLRSQLSQQWIKEAGFDIPYIQGGYKALRTFLIQILESSAALNSMLILSGRTGSGKTDFLQLRDEAVDLEQLANHRGSSFGKNLDPQPSQINFENQLAIAVLQHQTKHHRHLLLEDESFLIGRSALPKAFYNSMQHADIVLLEEDDEQRLQRLLFDYVDNKLASFVSRLGDEAGLKAFGDYLNASLNGIKKRLGGKFLQELLDSVARALAHQISQNDTSLHLDWISQLLTRYYDPMYDYQLSQKQQRVLFKGDHASMHAWLDELRK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Length
367 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.719 kDa
Sequence
MRPDTADFRTLFLSGVAMLDVRAPLEFARGAFPGAVNLPLMDDAERHEVGLCYAQKGQQAAIELGHQLVSGLRKAARIAAWAEFARAHPDGYLYCFRGGLRSQLVQQWLHAAGVDYPRVTGGYKAMRGFLIETTDAAAAEQQWFVLGGLTGSGKTDVLADVPAAIDLEGHARHRGSAFGRRALAQPPQIDFENALAIDVLRHIDAGWRALLVEDEGRFIGSRDVPQVLTQRMQASPLVWLEASFDERVERVLRDYVQGLAAEFIAEKGSTEGFEAYATRLREAMAGISPRLGGARYGKLSALLDQALAQQAERGEVDLHRGWIEVLLREYYDPMYAFQREQREARIVFRGDRAAVTDWLRAHTAQRG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
366 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.08 kDa
Sequence
MADNSSDYRALFLNDVPMMDARAPVEFSKGAFPGVINLPLMNDIERQKVGTCYKQHGQDAAIQLGHQLVCGQVKDERVEAWVEFARANPNGYLYCFRGGLRSQTVQRWLKDAGVDYPRILGGYKAMRTFLLDTLHEAVTECDLVVLGGMTGTGKTEVLTQLPNGLDLEGVANHRGSSFGKRATGQPAQIDFENRLAINLLKKRAAGIEQFVVEDESRLVGSCNVPLELHQAMQGCPVVWLEDSFEHRVERILADYVVNLCAEFISVKGEELGFGLFADRLLQSLNNIHKRLGGERHQRLLALMQTALEEQQRSGAVELHRGWIEGLLGEYYDPMYAYQREHKAARIEFAGNQFEVSGYLSERSSRR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
366 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.261 kDa
Sequence
MADNSSDYRALFLNDVPMMDARAPVEFSKGAFPGVINLPLMNDIERQKVGTCYKQHGQDAAIQLGHQLVCGQVKDERVNAWIEFAKANPDGYLYCFRGGLRSQTVQRWLKDAGVDYPRVLGGYKAMRTFLLDTLHEAVSECSIVVLGGMTGTGKTEVLTQLRNSVDLEGIANHRGSSFGKRATGQPAQIDFENRLAIDLLKKRAAGIEQFVVEDESRLVGSCNVPLELHQAMQGCPMVWLEDSFENRVERILEDYVINLCAEFITVKGEEQGFGLFAERLLQSLNNIHKRLGGERHQRLSDLMQAALEEQQRSGAVDLHRGWIEGLLGEYYDPMYAYQREHKAARIEFAGDQTQVLAYLRERSEQR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)
Length
366 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.365 kDa
Sequence
MADNSSDYRALFLNDVPMMDARAPVEFSKGAFPGVINLPLMNDIERQKVGTCYKQHGQDAAIQLGHQLVCGQVKDERVNAWVEFAKANPDGYLYCFRGGLRSQTVQRWLKDAGVDYPRIIGGYKAMRTFLLDTLHEAVSECDIVVLGGMTSTGKTEVLTQLRNSLDLEGIANHRGSSFGKRATGQPAQIDFENRLAIDLLKKRAAGIEQFVVEDESRLVGSCNVPLELHQTMQGCPMVWLEDSFENRVERILDDYVINLCAEFITVKGEEQGFGLFAERLLQSLNNIHKRLGGERHQRLSGLMQTALEEQQRSGTVDLHRGWIEGLLGEYYDPMYAYQREHKAARIEFAGNQVDVLDYLRERSDKR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella frigidimarina (strain NCIMB 400)
Length
366 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.556 kDa
Sequence
MSEVIPSSEYGRLLLENRPLIDVRAPIEFTKGAFGHSINLPLMQDGEREKVGTCYKKRGQEAAIALGHELVKGKVKQQRIDAWLAQLSQHPDSYLYCFRGGLRSKLSQQWIKESGMDIPYIEGGYKAIRSFLINTIEQAPSQSKVLILSGITGSGKTEVIHQRDESVDLEGLANHKGSSFGKNIDPQPSQINFENNLAVALLKHQQQQHNHLLLEDESMLIGRSALPKHFYSAMQQADIIVLDEPLDARLPRLLNDYVEQKLTDYVSGLGEQAGFDAFKAYLAQSLLGIRKRLGGKQHQELQDLVDNALNVQQSQNDTSKHLDWINLLLDIYYDPMYLYQLEKKQDRVIFQGDRQAIHQWLDKHKS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Length
366 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.024 kDa
Sequence
MSALPLATDYARIFLDDVPLIDLRAPIEFKEGAFPCSTNLPLMTDDERAQVGTCFKQQGQAAAIALGHQLVGGAVRAERLEGWLAQLRRQPDAVLYCFRGGLRSQTVQQWLHEAGVTRPRIAGGYKDLRRFLIDTLDGAAAECQWTVLTGMTGSGKTHMLAEVAQALDLEGHAHHRGSSFGQLPGGQPSNINFENNLAIELLKRRHQGEQAFVVEDESRLIGRCCLPNPLFDAMSQAPLVVVEVPQEERAEQIRQDYVHDLWLRYQAMFGAEEGWPLFAAYLTDALARLKRRLGDQAHRELDTLMQSALAEQASSGDTSLHLAWITLLLTRYYDPMYLYQLGNKRERIIFQGDKQACLDFFAKQRA
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Cupriavidus necator (strain JMP 134 / LMG 1197)
Length
366 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.128 kDa
Sequence
MREDTGDFRRLFLSGTPMMDVRAPLEFARGAFPGTVNLPLMDDEERHQVGLCYAEKGQHAAIELGHRLVWGALKATRIAQWADFARAHPDGYLYCFRGGLRSQIVQQWLRDEAGIDYPRVTGGYKAMRGFLIDVIEQAAAKQDFLVLGGLTGTGKTDVIAEVPAAVDLEGLACHRGSAFGRRAQPQPQQIDFENSLAIDVLQRAEAGYRALVVEDEGRFIGGRDLPKVLWQRMQASPMVWLEASFEERVERVLRDYVLGLAAEHIEQLGPVAGFEAYATRLRDAMAAISPRLGSERYGRLSALLEQALTSQSERGETAPHRAWIEVLLRDYYDPMYAYQEEKRAARVVFRGDRAAVTDWLRERSAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas putida (strain W619)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.592 kDa
Sequence
MRHDCTDFRQLFLDDVPMMDMRAPVEFAKGAFPGVVNLPLMTDQERQKVGTCYKQQGQAAAITLGHQLVSGTLKRERLHAWASFAKAHPDGYLYCARGGLRSLIVQQWLRDEAGIAYPRIKGGYKALRTFLLDTTQQAVEQCDFVLVGGLTGTGKTDVLHQLNNVIDLEGHANHRGSSFGKRATAQPAQIDFENKLAIDVLKKRARGIEQFVLEDEGRIVGSCTVPLELYQGMQQYPLVWLEDSFENRVERILRDYVINLCAEFVALHGEELGRRLFAERLLQSMSNIHKRLGGERYQRLSEIMRLALDEQQRSGGIDLHRGWIEGLLKEYYDPMYAYQRDAKADRVEFAGDAVEVREYLKARNR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Psychromonas ingrahamii (strain 37)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.565 kDa
Sequence
MQQSDLQEQQLYRSLFLLKTPLIDLRAPVEFAQGAFPESCNLPLMTDNEREQVGTCYKKEGQAAAITLGHQLVASDIQNRIRKWAQFKEENPTAWLYCFRGGLRSRLSAQFLKDHGVDINIVPGGYKALRRYLINVIDQASEKKLMIVGGNTGCGKTLLIQALDNGLDIEGRANHRGSSFGKQVTEQPRQISYENQLAVDILHISQHASSLVIEDESKAVGALYVPERLFAGMTRAPMVVVNDPLEIRLQRLCYEYCTLMTEKFNLALGAEQGWQAYEKYLQNGLYGIRKRLGTEKFKVMNTVLEAALKQQKNTGSVEGHLNWIASILRDYYDPMYQYQLEKKADRVQFRGTFQEVKEWLTVNTK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella halifaxensis (strain HAW-EB4)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.605 kDa
Sequence
MSLNKVRASEYRRIFVNDHPIMDARAPVEFEKGAFPASVNHPLMEDEERKKVGTCYKERGQEAALKLGHSLVHGEIKQQRVDAWLDFFSKNPDGYLYCFRGGLRSQLTQQWLKEAGLDIPFIEGGYKAMRQFLIETIDDAPNMKPMLILSGITGSGKTDFLLKRKEAVDLEGLAHHRGSSFGRYHEPQPSQINFENALAVALLKHQDSAAKHLLLEDESYLIGRSALPQAFYTGMQAAGVLVLEESLDARLARLLNEYVHKMHSGYIQRLGEEAGFEAFAQYLAQSITGIKKRLGNKQHDEFQAIITNALNIQTSQNDTSAHLEWIELLLVKYYDPMYQYQIDKKADRVIFKGDHQAMHQWLDNH
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.492 kDa
Sequence
MTLNKVPASEYRRILVNDHPIMDARAPVEFEKGAFPASVNHPLMEDEERKKVGTCYKEHGQETAIKLGHSLVQGEIKQQRVDAWLDFFTKNPDGYLYCFRGGLRSQLTQQWLKEAGLDIPFIEGGYKAMRQFLIETIDNAANVKPMLILSGITGSGKTDFLLQRKEAVDLEGIAHHRGSSFGRYHEGQPSQINFENALAVALLKHQDTDAKHLLLEDESFLIGRSALPQAFYSGMQTASVLVLEESMDARLTRLLNEYVHKMHSGYIQRLGEEAGFEAFAQYLAQSITGIKKRLGGKQHDELQAMITDALSIQTSQNDTRGHLGWIELLLVKYYDPMYQYQIDKKAERILFKGDHQAMHQWLDDH
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella piezotolerans (strain WP3 / JCM 13877)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.464 kDa
Sequence
MPVNMVSASEYRRILVSDHPIMDARAPVEFTKGAFPASRNHPLMEDEERRLVGTCYKQNGQQAAIDLGHSLVTGEIKQQRLDAWQRYFTKHPDAYLYCFRGGLRSKLTQQWLKEAGIDVPFIEGGYKAMRQFLIETIDNAASQNPMLILSGITGSGKTDFLLARNDSVDLEGIAHHRGSSFGRYHEPQPTQINFENALAVALLKHQDSQAKHLLLEDESFLIGRSALPQAFYKGMQQANVVVLEEPMEARLTRLLNEYVHKMHSGYIQRLGEEAGFAAFAEYLALSITGIKKRLGGKQHDEFQAIITNALNIQQSRGDTSAHIEWIELLLSKYYDPMYQYQIDKKAERILFKGDHLAMHQWLDAN
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shewanella sp. (strain ANA-3)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.345 kDa
Sequence
MTTKLIPAQQYHDIFIAGQPLIDLRAPIEFDRGAFPSSVNLPLMVDKEREKVGTCYKAQGQQAAIALGHSLVHGVVKQQRIDAWLNFLSANPEAYLYCFRGGLRSQLTQQWLQEAGVTAPYVQGGYKGMRQYLIGVIETAPSQQPLLSLSGMTGSGKTDFLRLRKEAIDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLRHQLGNHACLLLEDESFLIGRSALPQSFYSAMQTADIVVLEEDDDIRLTRLLDEYVHKMHLGFSERLGLEAGFEAFSHYLLQSLGSIRKRLGGKQYQELQDMMQQALSQQLNQNQTSQHMAWISLLLHKYYDPMYEYQLQKKAGNILFRGSHQAMHEWLDNY
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Verminephrobacter eiseniae (strain EF01-2)
Length
365 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.257 kDa
Sequence
MRQDDAQLRHIFLHDVPLLDVRAPVEFAQGAFPGAVNHPLMDDAERHQVGLCYRQQGQPAAIALGQQLVSGHTRRERIAAWAAFAQAHPDGLLYCLRGGLRSQIALQWLHSEAGIAYPRVPGGYKALRMFLIDTTQAAAQECDFVLLSGLTGTGKTALIAQLAQGLDLEGHANHRGSSFGQRLDGQPSQVDFEHRLAIDILKKQARGHRAFVLEDEGRHVGRCSVPLALRQRLERAPIVCLQDSFGARVERIVGDYVIGQCADFVAAHGPALGFERFSTRLLDSLGKLARRLGGARYQQLHADMQAALARQQASGDIDLHRHWIAALVRDYYDPMYAFQRQSRPGRIVFEGDLPAVLAYLRAGCG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.193 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERVAVGTCYKQQGSDAALALGHKLVAGEIRQQRMYAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTTIQATIELAQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLATGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.246 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALAQGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDAHQDLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFHGEWAEVAEWVKTQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.27 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELSQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain 55989 / EAEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.147 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTTIQATIELAQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLATGSTDSHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O157:H7
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.074 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O157:H7 (strain EC4115 / EHEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.074 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O81 (strain ED1a)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.22 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRIDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENMLAAEMLKTDAHQDLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O8 (strain IAI1)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.117 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTTIQATIELAQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLATGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.111 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEHGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain K12 / DH10B)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.111 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEHGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O9:H4 (strain HS)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.075 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O1:K1 / APEC
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.27 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELSQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.234 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRIDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELSQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDAHQDLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.075 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain K12)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln) (PubMed:14594807, PubMed:22983156, PubMed:24971911, PubMed:29862510). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA) (PubMed:14594807, PubMed:24971911, PubMed:29862510). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain (PubMed:24971911, PubMed:29862510).
Similarity
Belongs to the SelU family.
Mass
41.111 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEHGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.22 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQRWLHEAGIDYPLVDGGYKALRQTAIQATIELSQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQELRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain SE11)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.129 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLYAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.118 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKSR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella agona (strain SL483)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.331 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDNERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINAHQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSNGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella choleraesuis (strain SC-B67)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.324 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella dublin (strain CT_02021853)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.324 kDa
Sequence
MQDRQKAQDYRAILLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella enteritidis
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.3 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIDQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSKYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQEVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella enteritidis PT4 (strain P125109)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.342 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQEVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.324 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMIDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQEVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella heidelberg (strain SL476)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.271 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFICMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella newport (strain SL254)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.324 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.367 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLKETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINAHQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQDVANWLKEQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.28 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMGDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLKETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLKPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella paratyphi C (strain RKS4594)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.324 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella paratyphi A (strain AKU_12601)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.367 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLKETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINAHQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQDVANWLKEQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella typhi
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.27 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLKPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDGAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli (strain UTI89 / UPEC)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.27 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELSQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.23 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPVEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQRWLHEAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGCGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQELRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFIHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELATRLDAALTTQLATGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Photobacterium profundum (strain SS9)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.108 kDa
Sequence
MLMPRQNCEVFRQLFVNDTPLMDMRAPIEFAQGAFPTSINHPLMEDEERKAVGTCYKAHGQDAAIALGHQLVNGDIKAARLAQWKAFAEENPNGYLYCFRGGLRSRITQQWLKEAGIDYPMVVGGYKALRRFLIETIDTVAQQPMTIVGGNTGSGKTIMVNELANGIDLEGAANHRGSSFGRYVTAQRTQIDFENVLAVEMLKKQAQGCTHFVFEDEGRAIGSASVPLSINAAMGNADVAIVDDPLDVRIDRLIDDYVVRMQRDYIAQNGEQQGWELFTEYLERGMFGIRKRLGMKRYEELLAAQKQAIATQKSNGTLAEHDNWLRPLLIEYYDPMYTYQLSKKADRIVFRGNYQEVKSWLADK
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.161 kDa
Sequence
MPLDCTDYREIFLNDRPMMDTRAPIEFTKGAFPGVLNLPLMTDQERQRVGTCYKQQGQQAAIVLGHQLVSGAIKEQRIQAWADFARAHPDGLLYCFRGGLRSQIVQQWLREAGIDYPRVGGGYKAMRTFLLDTTEQALQQCDFVLLGGMTGTGKTQVLGQLDNALDLEGHANHRGSSFGRRATGQPSNIDFENRLAVDLLKKRERGVQSFVLEDENRMIGSCALPLPLYQSMQGLPMVWLEDSLANRVQRILDDYVVNLCAEFVAVHGEQGFALFAERLLESLNKIHKRLGGERHQRLFLLMEAALAEQARSGDVERHRAWIEGLLGEYYDPMYAFQRESKGARIEFSGEHGAVLDYLRQRSPR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln) (PubMed:27073879, PubMed:7520175). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA) (PubMed:7520175, PubMed:27073879). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain (Probable).
Similarity
Belongs to the SelU family.
Mass
41.328 kDa
Sequence
MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.086 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRIDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shigella boydii serotype 4 (strain Sb227)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.086 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRIDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.102 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shigella flexneri serotype 5b (strain 8401)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.222 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMDNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMYAWRAACLQNPQGILCCARGGQRSHIVQRWLHEAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAVWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shigella flexneri
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.238 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMDNDERASVGTCYKQQGSDAALALGHKLVAGEIRQQRMYAWRAACLQNPQGILCCARGGQRSHIVQRWLHEAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAVWVKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Shigella sonnei (strain Ss046)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.16 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLYAAGIDYPLVEGGYKALRQAAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTDSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKTQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.705 kDa
Sequence
MTLLFDDFKSIVLNKTPLLDVRAPVEFKKGAFLNAVNLPIMNDEERHKIGICYKNEGNAKAVELGHSMVSGDIKEERIKAWIAFMDANPNALLYCFRGGQRSKISQEWLHVRGKEILRLKGGYKAFRTYLINKLSESTQHFKPIILGGRTGSGKTIVLEKMKNSIDLEGLANHRGSSFGSKLNAQPMQIDFENNLAYELIQKIEDGFKTLVFEDEGKHIGNAFMPENLISTAINAPLIILETQIDKRVEITLNEYVVQAQEAYLEAGFDFVLEEWSQSIQNAMKRIVRRLGNEKYTKVTAIFESALDEQKKSGSYDGYKEWAKFLLEEYYDPMYDYQIQKRSHMVAFRGDAQEVQNYIERLSDI
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Sulfurovum sp. (strain NBC37-1)
Length
364 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.921 kDa
Sequence
MEELPQSSDFRSIVLNNTPLIDVRAPVEFAKGAFPHAVNLPLMNDEERHVVGIKYKEEGNAEAVKLGHALVSGDVKEARIKAWTDFIASHPDAMLYCFRGGQRSQIAQEWLAENGREIVRLKGGYKAFRNWLMQETEKAVEQFKPIVLGGRTGSGKTILLKKLQNAIDLEGLANHRGSSFGRDITPQPTLIDFENALAYDLIQKLDQGFEHLVFEDEGKCVGRIYLPKILVEHLSEAPLVVLETPTEKRIEITFDEYVAKAHEKYKEVYHADYLKVWTEDMHEAMKRIQKRLGGQRYKIVCEIFEDALKEQKKNSSLEGYKVWIAYLLSEYYDPMYDYQIERNASRILFRGNAQEIEAFLKEYR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Proteus mirabilis (strain HI4320)
Length
362 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.167 kDa
Sequence
MESTLSAQNIRRLLANETPIIDVRAPIEFNQGAMPNAINLPLMNNEERAAVGTCYKQHGSQKAVELGHQLVKGEIKAHRVAAWREACERFPSGFICCARGGMRSHIVQKWLAEIGIDYPLIEGGYKALRQATIEMTNELVQRPIILIGGCTGNGKTTLVRSLPEGIDLEGFAHHRGSSFGRTVEAQFAQATFENYLAVDMLKKSSYHSRWVLEDEGRAIGANGLPESLRIQMATAHLVVVDDPFERRMARLKEEYFDRMTHDFIEAYGEEKGWQEYSDYLHHGLYAIRRRLGAQRAAELTQLLDNALAAQKISANTEVHFSWLSPLLKEYYDPMYRYQLSKKQDKIIYTGSYEEVEQWFANH
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)
Length
362 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.146 kDa
Sequence
MRDDTCDYLSLFLNDTPLLDVRAPVEFAKGAFPGTTNLALINDEERHRIGICYKQHGQQAAIDLGNTLVCGEERERRLYAWQQWWQANPNGYLYCFRGGLRSQTTQAWLREIGIDAPLVTGGYKALRRFLIDEMEACIANLPLEVLCGRTGCAKTRVIEQQPNAIDLEGLAHHRGSSFGRRPGGQPSQIDFENSLSIALIKQRAAQPVSILVEDESKLIGRCHLPFSLQDQIKSQPRIIIEESLESRVQVTLEDYVIGPLQEYARYFGEHDALKQLGDELLASMDRIRRRLGGIRHQQLRQQLQEALAVQANCGNTELHREWIHSLLADYYDPMYDYMLSRRAGTILFQGSRAEVSAFLNSR
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
361 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.643 kDa
Sequence
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGICYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPHGILCCARGGQRSHIVQRWLHDAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENMLAAEMLKTDAHQDLRLWVLEDESRMIGSNHLPECLRERMTQATIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAGSGGMG
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Length
361 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.021 kDa
Sequence
MNHETNYHALLIADTPLIDVRAPIEFQQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALSLGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLVQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLKPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPITVVEDPFALRLERLREEYFIRMHHDFIHAYGDEGGWQAYSEYLHHGLFAIRRRLGLQRFAELTNTLDMALADQLSNGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQEVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Salmonella schwarzengrund (strain CVM19633)
Length
361 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.919 kDa
Sequence
MNDGTDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLKPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMVQAPIAVVEDPFSLRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQDVANWLKAQ
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Hydrogenovibrio crunogenus (strain XCL-2)
Length
361 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
41.704 kDa
Sequence
MVPQSDDFERIVLKNIPLIDVRAPVEFAQGAFEMAHNLPLMNDEERQTVGICYKQKGHDEAVKLGHRLVNDKVRLPRVSGWQSFMEKYPEAMLYCFRGGMRSKIAQQWLADNGCEIVRLKGGYKAFRRYLIDHLEIMPQRFSTEGIQTWALGGRTGCGKTRLLHTLDNAIDLEGLANHRGSAFGGHVAPQPTQINFENTLAMAVMRFYAQGHSSLVLEDESHCIGSVSVPKTFFDFFKGGRQVLLEAPLEERVSITREEYVEQAQAEYETTEDWTVFMRSAFGRIRKRLGGERYQRVLKKFDQACENQHRTQEFDAHDDWIRILLTEYYDPMYDYQMQKKQCKIDFSGNFDAVKDFLSQQS
Protein
tRNA 2-selenouridine synthase: selU

Gene
selU
Protein
tRNA 2-selenouridine synthase
Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Length
361 amino acids
Function
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
Similarity
Belongs to the SelU family.
Mass
40.85 kDa
Sequence
MSLPHLAPEMALLERPLIDVRAPVEFARGALPGAVNLPLMDDAERHAVGIRYKEAGQGAAIALGERLVDGDLKARRVAAWRAFAERHPDAVIYCFRGGLRSRIAQQWLQEAGITLPRIQGGWKAMRQCVNAEIEAAAARPVLVVAGLTGCAKTELVQSLDVGIDLEGHARHKGSAFGRHPLQGPSQIDFEHALGAALSHATHGCVVEDESRMIGQLDIPLSFWQTMETAPRIRVEMPLDWRLEQIRKDYIDTLWRTYRDHYGEWLGWSLMRKQLSSALKRVRKRLGSARFQRLQRLQALAFREHQRGNTQAHEAWLAPLMLEYYDPMYRYQLEQSPYEALHVGDWESCLAFARDWSAALPR
Protein
tRNA 2-selenouridine synthase: selU