Protein
Histone chaperone rtt-106
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
Similarity
Belongs to the RTT106 family.
Sequence
MAAKLDSQLLGLVFQSRPDILKGIQEAADSPARIDLFNNIASFVYERIADNTSEEPATKRRRVEAQTSGPNGAAHPIAGSQAAVLGADAAAAEPVLLEIKDISVSVPQRKKYDLCFTKNFLYARASGSPVPVQGIVYPWKDIEHAFYLPVPDKSQVQHNYVLLPRNSYLPTTKSQQSADQQTQQQTSAPLEPLVFTIPSTAPKPGTITGPSAAAAAPVSDSYATLFHWALTTSLHAAGNHACELVSSDPKVFHSVARQAYRPQEKAVHVKAFRGSKDGFLFFLPTGILWGFKKPLLFLPLDKIVAISYTSVLQRTFNIVVELEGGGEGSEEGGQEIEFSMLDQEDYAGIDQSYVRRHGLADRSMAEQRKAKKQLAENAKKAAANGEEGEGGEGGEAGDGLTELERAQKEEEQRLQDEEDEEEEDYDPGSEGESEGSGSSSEEEEEEEDGEGEGDEDDDEDMGEGLEGEE