Description
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
Family
Belongs to the RTT106 family.
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Sequence
MAAKLDSQLLGLVFQSRPDILKGIQEAADSPARIDLFNNIASFVYERIADNTSEEPATKRRRVEAQTSGPNGAAHPIAGSQAAVLGADAAAAEPVLLEIKDISVSVPQRKKYDLCFTKNFLYARASGSPVPVQGIVYPWKDIEHAFYLPVPDKSQVQHNYVLLPRNSYLPTTKSQQSADQQTQQQTSAPLEPLVFTIPSTAPKPGTITGPSAAAAAPVSDSYATLFHWALTTSLHAAGNHACELVSSDPKVFHSVARQAYRPQEKAVHVKAFRGSKDGFLFFLPTGILWGFKKPLLFLPLDKIVAISYTSVLQRTFNIVVELEGGGEGSEEGGQEIEFSMLDQEDYAGIDQSYVRRHGLADRSMAEQRKAKKQLAENAKKAAANGEEGEGGEGGEAGDGLTELERAQKEEEQRLQDEEDEEEEDYDPGSEGESEGSGSSSEEEEEEEDGEGEGDEDDDEDMGEGLEGEE
Simulated SDS-PAGE
![Western blot of rtt-106 recombinant protein](/recombinant/rtt-106-1.png)
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service