rsgI3

Anti-sigma-I factor RsgI3

644 amino acids

Anti-sigma factor for SigI3. Negatively regulates SigI3 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI3 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI3.

72.68 kDa

MDNIGVIIKIEGNEAIVMTDDCSFKKVPIKDGMHPGQKILVPNNEVIQKENKSIKRISAVATGIAAVFLMVLSLIWINKPGRPDGIYAYIDVDINPSLNFLIDREGKVKALNPLNDDAQEIIRGVEFEDMFFSEALTQIIKISKAKGIIDENKTNYVLICAALDDNYNLQSDDKSRAQTEFEEFLDGIRESIEKACGNTVIPQTVKVPFEYLKMAKQNDVSMGRYLVYQKLEDIGVNLSIEELKSLDIDEILKKYGVGFDELFKSEYTELPYGTLQTGEDSVVSTEDVPVSPKNAFETMAVPTNTPSISTKPSATPAENPTPKLTQKPTPVPAKTGERTSTTPTPTPAPTVRNGTGSGLRGEYYNNMDFSRFQFVRIDPCIDFDWGEGTPDQSIGKDTYSVRWTGKVEPRYSETYTFYTVTDDGVRLWVDGVLLIDKWKSQSATEHSEQIYLEAGKKYDIKMEYYQHVRAASAKLMWSSKSQQKEIIPSSQLYPSDGPLPQKDVNGLSAEYYGDAELKDKRFTRIDDAINFNWDKDFPVGELKDGKFSVRWVGKIDTRYTEEYTFHTVANGGVRVWINNVLIIDNWQNQGKEAENSGKIELKAGRQYDIKVEYCNYGEPAFIKLLWSSQRQKKEVVPSKNLFAD