rhsC

Putative deoxyribonuclease RhsC

1658 amino acids

Putative toxic component of a toxin-immunity protein module, which may function as a cellular contact-dependent growth inhibition (CDI) system. Expression of the C-terminus (residues 1519-1658) in E.coli inhibits growth but does not alter nucleoid structure. Its effect is blocked by cognate immunity protein RhsIC.

Belongs to the RHS/WapA nuclease family.

184.883 kDa

MSQDKKATLLSSEDAANQNFATDNQISGGCAKCGCEVLIHYHYDSGKPVPNAPFILIDSNKTEIHGKTDANGLCKIYDMGCGTFELMLDEGSDDFKPRETVENNPVLQSNPAYATLAGEYFTLFLLLRKQGLVTYDADDSSDRHVDVDGAGIFTSIPKEYRKSYDRFWELDKRINRGSRQLKQAINKIHHSLAAEVADKGGDDNAALMLFCEIALGFIPVVGQAMDVYSIGEWSWQSYQEPARLEDPLHIAEGALCAIGVIPGLGDALKVSGRAIIRALKVGTPKELQFAIRTIRSLSDGNLVKGLTKLRAELRNYGAQAKALLLKIHAALKQVLAESKLKNNWIVSLMKDSFSAMITSLEKLIAKYDSALAYIESKFNEFIGKVITRVSGSARPKGSIAKAAEAPKAPAHAESQAAKPATPKSDNSITKADDGKPTNAVSEKKRRTSSKETEDISAGSNKGEQPDHAPQQKKAGEEDNACKAGSDKCQGEGEPVDMATGYVVDWRTDVELTGLLPLSMKRYYRSGGERKPGLLGALWRTNWDMSLELENGIATLTDGELNQAVFVLPDEGAFSRAPSSPQWRLARQQGQLVLQHVDGLRYRFEHALGLQLCLSAIEDRAGNRIALLWDRAELCWIVLPDGRLVHVETQQRRIVKLTLCDEHRQPLKTLSSYQYDAQGHLLSVRAGEGRNFDYQYSPQGWLLRWSDLAHTWVEHEYDAAGRALRDRTAEGFWPGAFRYDDDAFTSHYHSGFGGVTTYVRDARNNILLRREPDGGEHRFEWVDNQLAAEIDPLGGRTEYQRNDWGQVTAVTLPDGSVHRYDYDDDGQLLAYTDPLGNAWHYSRNAQGLVETASDPEGRSWHHAYTTQGLLSAVNGPDGCEQRYHYNRRGLLERLEPGEAPAVTFFYDGHDRLTARHIAHEQGVQVRRWDYEGGRNTPSKVVYEDGSETRFGYDGEGNLTSVTDALGQRYLFRYGAFDNLLETTDPLGATVRYHYNAESEFAGVTNSQGQMWQYRFDTAGRLSEERHYDGRVYRYDYDVAGQLTRRTAPDGSRLEYGYDVGGRLSEIQACRADGASEGATTFTYDLSGRLLKAASPDAVVEYAYNRAGQVVSERVNGEEVRTGYDDGGQRSVVEGLLSSLSLGWQGGRLTTLSIGSHQPLTFSHTASGYEQRRSNGEGFALRHEWSATGLLSGQALDGVNGVLERRYQYDVLDCLTGITDSHWGEQAFRLNGAGQVTAERREQGRQRQARLFGYDSEQNLCEVSAIAPDGAGRLSAKNAAVQLSSGYDEAGRVTQRGGRQYQYDACGRLVSRRESRPGFRPQETRFEWDAQDRLVRVSLPDGARWRYGYDAFGRRVSKVREGQVPSAQAVARVAYRWDGDQLSGQTQYRVDGSVTRAVQWVYEPGSFRPLAQVEEQAGQTRLHYIVADLTGTARELCSETGEVHWRGEQGLWGPHREEKIPIPLRRYLGDAANEEVYCELRYQGQVYDAETGLYYNRHRYYDPELGQYISADPIGLAGGLRPQGYVHNPMEWVDPFGLVGCPLKDSPLGKNGVELERTVSKKGNVKVDTLFENSNDAKNWAAEKLGPGKTRMYDSNGKWIGWQNKTGDSVYWGHNDWGKGVGKSTYPHLNININGEKGHLFLRDKIINRGQWDDFSNAFK

rhsC

Protein RhsC

1397 amino acids

Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell.

Belongs to the RHS family.

157.776 kDa

MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVTSGHPVNPLLGAKVLPGETDIALPGPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADIRLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQALPEELRLSPHRYLATNSPQGPWWLLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGRTQTFHREAAGEFSGEITGVTDGAGRHFRLVLTTQAQRAEEARQQAISGGTEPSAFPDTLPGYTEYGRDNGIRLSAVWLTHDPEYPENLPAAPLVRYGWTPRGELAAVYDRSNTQVRSFTYDDKYRGRMVAHRHTGRPEICYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLHTQGEGGLKRVVKKEHADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHSQLTSATGPDGLEIRREYDEWGRLIQETAPDGDITRYRYDNPHSDLPCATEDATGSRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFGQVTAVHREEGLSQYRAYDSRGQLIAVKDTQGHETRYEYNAAGDLTTVIAPDGSRNGTQYDAWGKAICTTQGGLTRSMEYDAAGRVIRLTSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYDEADRLTHRTVNGETAERWQYDERGWLTDISHISEGHRVTVHYGYDSKGRLASEHLTVHHPQTNELLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSGWLSGMKLGDTPLVEYTRDRLHRETLRSFGRYELTTAYTPAGQLQSQHLNSLLSDRDYTWNDNGELIRISSPRQTRSYSYSTTGRLTGVHTTAANLDIRIPYTTDPAGNRLPDPELHPDSALSMWPDNRIARDAHYLYRYDRHGRLTEKTDLIPEGVIRTDDERTHRYHYDSQHRLVHYTRTQYAEPLVESRYLYDPLGRRVAKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQNDRTRIQTIYQPGSFTPLIRVETATGELAKTQRRSLADTLQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLASCGLTVAQMQSQMDPVYTPARKIHLYHCDHRGLPLALISTEGTTAWYAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNFYQYPLNPISNIDPLGLETLKCIKPLHSMGGTGERSGPDIWGNPFYHQYLCVPDGKGDYTCGGQDQRGESKGDGLWGPGKASNDTKEAAGRCDLVETDNSCVENCLKGKFKEVRPRYSVLPDIFTPINLGLFKNCQDWSNDSLETCKMKCSGNNIGRFIRFVFTGVM