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popdc2

Gene
popdc2
Protein
Popeye domain-containing 2
Organism
Danio rerio
Length
370 amino acids
Function
Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding.
Similarity
Belongs to the popeye family.
Mass
41.033 kDa
Sequence
MNSGDSSLIDAVIYNHTLCDGWTNSTEGAIYHLGNTILFLGYMGGSGAYGALYIFSFLAPAFLCLALWGWLTMCGLDVFIWNLLLMLQCLAQVCHLIFRLMRDGLANEEFSALYTAVYLPLDVPVQVFKEITGAGENKVLSLAAEETYAVEGKTPIDQLSFLLSGRIRVSLEGQFLHYIFPHQFLDSPEWESLRPAEEGNFQVTLTAETDCRYISWRRRRLYLLLSKDRYIARLFSVMLGSDIADKLYSLNDKLFAKSGVRLDIRLPSLYHVLAPSPPGSEGGSASSPPRGSLGDPTVIKVDPAPSNPGSGTRNPQPDQGKNPVPKNPHQHWSSDTEMPSGEDSTSLILEDFADMTGSLMDYGHEREYLK

Gene
Popdc2
Protein
Popeye domain-containing protein 2
Organism
Mus musculus
Length
367 amino acids
Function
Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.
Similarity
Belongs to the popeye family.
Mass
41.252 kDa
Sequence
MSANGSSVAQLLWQPPVCRSWKPDVEGAVYHLANCFLLMGFMAGSGVYGCFYLFGILGPGYLCCVLWGWFDACGLDIVLWNVLLTVACLLQLAQLVYRVRVNTLPEEFNLLYRTLCLPLQVPLQVYKEIVHCCHEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLHPSEEGTFQVTLTAETECSYISWPRKNLYLLLNRERYISRLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLSPSASDGEPESEKDDEEALEAAVSPAQARPICIVPTPPCSAPPATTNFPVPLPRARMPRMPRPDSGNLASRRPLQNSSQVMSRSQAPLAPIHTPEL

Gene
POPDC2
Protein
Popeye domain-containing protein 2
Organism
Homo sapiens
Length
364 amino acids
Function
Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.
Similarity
Belongs to the popeye family.
Mass
40.448 kDa
Sequence
MSANSSRVGQLLLQGSACIRWKQDVEGAVYHLANCLLLLGFMGGSGVYGCFYLFGFLSAGYLCCVLWGWFSACGLDIVLWSFLLAVVCLLQLAHLVYRLREDTLPEEFDLLYKTLCLPLQVPLQTYKEIVHCCEEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLQPSEEGVFQVTLTAETSCSYISWPRKSLHLLLTKERYISCLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLGPTAADAGPESEKGDEEVCEPAVSPPQATPTSLQQTPPCSTPPATTNFPAPPTRARLSRPDSGILASRIPLQSYSQVISRGQAPLAPTHTPEL