polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)

Length

2289 amino acids

Function

Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

255.812 kDa

Sequence

MRDADKQYFETLESHLEQAFARARQAKGQGYDPKPEVEIPVARDMADRVENILAIPDVAERIRELDDERSREEVALELVTDFVEGTVGDYDTREGKIEGAVRTAVALLTEGVVAAPIEGIDRVEILSDDDGSEFVNVYYAGPIRSAGGTAQALSVLVADYARSLLDIDEYSARTDETERYAEEVSLYDRETGLQYSPKDKETKFITKHMPIMLDGEATGNEEVSGYRDLERVDTNAARGGMCLVLAEGIALKAPKIQRYTRQLAEVEWPWLQDLIDDTIGSDEHSNNSVKNGEADIVKTDKDTNESETEDGIDNDDYNDSGLEPANSPRADATNKYLRDLIAGRPVFGHPSAAGAFRLRYGRARNHGFATAGVHPATMHIVDDFIATGTQLKTERPGKAGGVVPVDSIKGPTVRLANGDVRCINDPEEAEKLQNGVEKILDLGEYLVNFGEFIENNHPLAPAAYVFEWWIQEFEASNADVQALRDDPTVDLESPTFENAMRWAKKHDIPLHPAYTYLWHDISVTEFDHLADAVAAGEITMNEVSDTNSASGNTSLRANTNTDDTLTIDTTPAIRETMERLLIEHHQDSDSIHIPAWRALALSLGIKIESDNDTGIGDRMWSLTDLSKHARKQDDGKSAIAAVNEVAPFQVRERAPTRIGSRMGRPEKSEDRDLSPAVHTLFPIGEAGGNQRNLSDAAQSFGDNTERGQISVQLGKRRCPYCETVGFELQCAECGRHTEPQFVCRECESVLSPDESGRVHCDRCERDVTSAEWQDIDLHQRYRDALDRVDERESSFEILKGVKGLTSSNKTPEPLEKGILRAKHGVSSFKDGTVRYDMTDLPVTAVRPKELDVTAAHFRELGYQTDINGNPLQFDDQLVELKVQDIVLPDGAAEHMMKTADFVDDLLEQFYELNQFYQIDERDDLIGELVFGMAPHTSAAVVGRIVGFTSAAVGYAHPYFHAAKRRNCFHPETKIWFRDTDNEWHHETIQTFVEDRLDDPEIDAVGTLVQEVDDNTDREISVPSIDDNGNERLQSVTAVSKHRAPNHLVQIETISGREITITPDHEMHIFEQGNLVSKQASKITSGEYAVIPKRLQTISPSSHTPQHDLLREFLTRDELTADRLIIHTSDPVRLCNRVFPEEVTSCKDAVEIMQNTACHLDKNKETLIGWLGEGRIPVALLRGFVETDEALLMSIPDDVQIGLRGEKVRIDRHIGFTEELTSLLGYYAAAGIVHTQTNPISYESAQQEQSRITFYNIDTQTQTDLLNALNSVFEIEPIQYNLDGEILGVPGELIRRVFDTVFDVGTQPSHKRIPQALFDASESHITSYLRCFFSTHDSLTTDTRDISATTVSREFKEDIIAALRRLGITAEVTTQQSRSVPEVLPDWYAIDDITHHDADNSLNLTRSYVISIASSDAVTLQRDRQAQEQIKYDAQGLIANNNAIHQSRQVTDGGRKDYITEPITDIEYVDADIDYTYCLTVSETHSLIVNDLSQKQCDGDEDCVMLLMDGLLNFSREYLPDKRGGSVAADSRLVAVSPDDKIVFTTIEDFWKKLNTPIERNGKFRKRTCVSEGWQTYAFDENHEASLRPIEKAIRYTADESEQLRRITTQLGRSLDITDEHSLFRYDDGIEEVAGDDLTAGDIIVAPRTLDVEVTQTTLDLSEYIHDNERCPSEQTGSGELNLASKSAISDSRNKETPGVTHNILPQRSKFTDEMTTLSPTAVGGLESEQNETLRVGESTGAIERYINVDDSFGWLLGQFIAQRSISTDALTMTVHTAAEKHAERIVATSDSVFGIKPTVNSIERGYEIVFPSVFDTIVSGLTAKEQSEPEQDVDHTHTDEIGIPECILHAPDDIVLSFLQGFILAENAQRKGNAASEASEMVSESETTVTLETPSVGVKDGLVFLCHRLGVITDISEKSGEEYSVHFEESRYTVSIATEGKTNPLDQILNGERPTMPEGVSVPVPDALLTIHESIANSPHIDQVIPDTVVQQETVSLETLQSLLTGLSTVDLPAQLEAKRDELTLLTEGDLSYLRVESVECVDYDGYLYDLQVGGEPVFTANWLYAHNSMDAPLVMSSRIDPSEIDDEAHNMDIVRQYPREFYEATRRMEDPDEWEEEVTIAEEYLDTDNEYTGFNHTHDTTDIAAGPDLSAYKTLDSMMDKMDAQLELARKLRAVDETDVAERVIEYHFLPDLIGNLRAFSRQQTRCLDCGESYRRMPLTGECRECGGRVNLTVHEGSVNKYMDTAIHIAEEFDCREYTKQRLEVLERSLESIFEDDTNKQSGIADFM

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

Length

1798 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

204.935 kDa

Sequence

MSEEIYSPEMKAYFESLQREIDRAYAIARKARAQGKDPSFDVEVPQATDMAGRVESLVGPPGVAERIRELVKEYGKEIAALKVVDEIIEGKFGDLGSKEKYAEQAVRTALAILTEGIVSAPLEGIADVKIKRNEWADGSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSDEHIERMVEEVDLYHRAVTRLQYHPEADEVRLAMRNIPIEITGEETDKVEVSHRNVPGVETNHLRGGAILVLAEGVLQKAKKLVKYIDKMGIEGWDWIKEFVEAKEKGKSSEENKDESKAEDTGTESVAEKKENVEKGFYYELYEKFRANIAPNKKYTKEIIGGRPLFAEPSTNGGFRLRYGRSRVSGFATWSVNPATMLILDEFIAIGTQMKTERPGKGCIVTPATTVEGPIVRLKNGSVVRVDDYETALKVRNEVDEILYVGDALVNFGDFVENNQTLLPANYVEEWWVQELVQAIKDLYEVELQPFAENDREAVEEAAEYLEVDPDFLWNLLKDPLRVKPDVETAIHLSTVLDIPFHPYYTLYWNTLQPEEVEELQKALLGAQIEWAEFRKNRFAKKVVLENDKNIKRYLELLGLPHRLERVEKKRKVIVVEYPWSAALLTPLGNLEWEFKAKPFYTVIDIINENNRIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGQSRDIKKAAEEGKTARVEIAFFKCPKCGHVGPEHLCPVCGTRKELLWHCPKCGADYPESDAKDFNYRCPKCDVELKPYAEREIKPADLLRQAMDNVKVYGIDRLKGVKGMTSGYKMAEPLEKGLLRVKNDVYVFKDGTIRFDATDAPITHFKPKEIGTSVEKLRELGYTHDFEGKPLERDDQILELKVQDVILPYEAGRYLLKVARFIDDLLEKFYGLPRFYNAEKMEDLVGHLVIGLAPHTSAGIIGRIIGFSDVLVGYAHPYYHAAKRRNCFPGDTRILVQINGLPQRITLRELYDLFEDERYENMAYVRKKPKADVKVYSFDPESGKVVLTDIEDVIKAPSTDHLIRFELELGRSFETTVDHPVLVYENGKFVEKRAFEVREGDRILVPNLKLPEKNIDYLDLLKEFSREEFAHLHDRIMVRGIAEWLRSVEADVKEDYLRRDSIPLSVLLRVLTEKEISIEEVPSCWLGFKRDKVRIKRFVPLKPLLRVVGYYLAEGYARESKSVYQLSFSMAEKEVREDLKRALREAFGDGFGIYERGGKVTVGSRILYLLFTEVLKAGKNAYSKRVPSLVFTLPREAVAEMLKAYFEGDGSALKSVPRVVAYSVNKALLEDIETLLLAKFGIRGYYTFDNNANRGNARGRLYHVERGTEAPVSKVYALNIAGEHYHRFFNSIGFVSERKNSIYELHAEKSPAQDRYSSQNGWLVKVRRIEYITPKDDFVFSLNAKKYHNVIINESIVTHQCDGDEDAVMLLLDALLNFSKYYLPEKRGGKMDAPLVVTTRLDPREVDSEVHNMDVVRYYPLEFYKATYELKSPKEVKVIERVEDRLGKPEMYEGIKFTHDTDDIGLGPKMSLYKQLGDMEEKVARQLALAERIRAVDEHHVAETIINSHLVPDLRGNLRSFTRQEFRCVKCNTKYRRPPLTGKCPKCGGKIVLTVSKGAIEKYLPTAKMLVTKYRVKDYTRQRICITEKDIKTLFENVFPEKQRTLMGFSADICEKMVKERTGHSNGKNGYLDEFNGKNGKASKKSGSLASKLSGKGKEPSKKKESAKPKRSEKVKNLTSFEAAAKNEQARGTAGNAKKAESEKPKRKKRKGISLDEFFGS

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactococcus lactis subsp. lactis (strain IL1403)

Length

1638 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

184.96 kDa

Sequence

MENLFEKLMEQIKMPPNLRRSSQFEHADIENVEVHTASKLWHFQLIFDEILPIDTYKLLTELTETAFSTIARTEISVSSRNQNIDEQNLNDYYQYALTLPELCDSAFSSIFKKYHLEKEEEKIHLMVEDNPQMDFFVEKYFPILEEKFKSFGFGEVRITPLVDQELTETQAAAHAEKVAARLAAQTAEQAQISEIKKQRSEERESKNTREAKPEFVETALSDGIFFGRKISGQSPITSMSFIAGEGFGVIFEGLVFEAAHREFTGKESGKVNHILELKMADETSTFMISKWGRKDEEIAQFDQIVSTVKAMNEKIIADRTDGEDNFTDSLSDALWLRVQGNIEHDKYKDDLVLTANAVVEIKPKPTIDRVALQIKAVKSDKIQLGREIKNNEPVTPMRSVSEFSTNGPVVFEGYVFKGELREIKSRKTGNISYLLEFEMTDYTSSFYVQKWLRGEEEIQLAKQIKAGLWCRVRGNVQRDNFKNDLVLQLTDLIEIPTQNVREDKSDEKRVEFHAHTNMSQMDAIPSASSLVAQAAKWGHKAIAITDHGGLQSFPEAHSAGKKNGVKIIYGVEANLVEDKIPIVYNETDVDMYESTYVVFDVETTGLSAVHNDLIQIAATKMHKGNPIDEFDEFINPGYRLSEFTTELTGITDDHVKNAKPLYEVLTKFQKFCEGTILVAHNATFDVGFMNMNYSRNGLPIITQPVVDTLEFARNLYPEMKRFGLGQLTKKFQIGLEHHHMANFDAEATGRLLFVFLEELRTRNTGWTSLLELNDKLVSEDSYKKVRPKHVTLYAKTQEGLKNLFKIVSFGNVKYYAGLPRVPRSVLEANREGLLVGSACEIGEVFDAAINKTFEETLEIAKFYDFIEVFPPALYRSLVVGGSFKSEKELEQTLKDLIKIGKTLGKPVLATGNLHYLNPEDAIYREIIVRSLGLGAEINWTQGHGEHAKPLPLPEAHFRTTDEMLEAFSFLDEKTAREIVIDNTQKMADEFDVLTPVRDDLYTPKMVFDGGETSEERIVRLTYEKAHEWYGNPLPDIIDARLEKELRSILGNGFSVVYIISQELVKRSNDRGYIVGSRGSVGSSLVATMIGITEVNPLAPHYRCPECQYFECYDDGSFGSGYDMPDKNCPKCDHKLIKDGHDIPFETFLGFKGDKVPDIDLNFSGDDQPLAHLDVRDIFGEDYAFRAGTIGTVAEKTAFGFVKGYERDYDQFYGNAEIDRLAAGSTGVKRTTGQHPGGIIVIPNYMDVYDFSPVQFPADDVNAEWQTTHFDFHAIHDNILKLDILGHDDPTMIRKLQSLSGIVPQDIPMDDPGVMKLFTGTESLGLTEEQLGVKLGTLGIPEMGTFTSMNMIAEAKPKNFADLLQISGLSHGTDVWSGNAQDLIRSGIADLSSVIGCRDDIMVYLIHKGLENGLAFTIMERVRKGMWNKIPAEEREKYVEAMREHDVPEWYIESCSKIKYMFPKAHAAAYIMMALRVAYFKVHHPILYYCAWFSIRATAFDIGVMGAGLEAVKAKMKEIKDKGFDATNVETNLYTTLELCNEMLERGFTFGKIDLYRSEATEFVIDGDTLIPPFVTMDGLGENVAKQIVAARAEGEFLSKMELRKRGGVSQTIIENMTNMGVLEGMPDDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus agalactiae serotype III (strain NEM316)

Length

1468 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

166.12 kDa

Sequence

MSELFKKLMDQIEMPLEIKNSSVFSSADIIEVKVHSLSRLWEFHFSFPELLPIEVYRELQTRLVNSFEKADIKATFDIRAETIDFSDDLLQDYYQQAFCEPLCNSASFKSSFSQLKVHYNGSQMIISAPQFVNNNHFRQNHLPRLEQQFSLFGFGKLAIDMVSDEQMTQDLKSSFETNREQLLEKANQEAMQALEAQKSLEDSAPPSEEVTPTQNYDFKERIKQRQAGFEKAEITPMIEVTTEENRIVFEGMVFSVERKTTRTGRHIINFKMTDYTSSFAMQKWAKDDEELKKYDMISKGSWLRVRGNIENNNFTKSLTMNVQDIKEIVHHERKDLMPADQKRVEFHAHTNMSTMDALPTVESLIDTAAKWGHPAIAITDHANVQSFPHGYHRAKKAGIKAIFGLEANIVEDKVPISYNEVDMNLHEATYVVFDVETTGLSAANNDLIQIAASKMFKGNIIEQFDEFIDPGHPLSAFTTELTGITDNHVRGSKPILQVLQEFQNFCQGTVLVAHNATFDVGFMNANYERHNLPLITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVALEHHHMANYDAEATGRLLFIFLKEARENRDVTNLMELNTKLVAEDSYKKARIKHATIYVQNQVGLKNIFKLVSLSNVKYFEGVARIPRSVLDAHREGLLLGTACSDGEVFDALLSNGIDAAVTLAKYYDFIEVMPPAIYRPLVVRDLIKDEVGIQQIIRDLIEVGRRLDKPVLATGNVHYIEPEDEIYREIIVRSLGQGAMINRTIGRGEDAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYEIVVTNTNTFADRFEDVEVVKGDLYTPFVDRAEERVAELTYAKAFEIYGNPLPDIIDLRIEKELASILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPNCQHSEFITDGSCGSGYDLPNKNCPKCGTLYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEEYAFRAGTVGTVAEKTAFGFVKGYERDYNKFYNDAEVERLATGAAGVKRSTGQHPGGIVVIPNYMDVYDFTPVQYPADDMTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPSNILPDDPDVMKLFSGTEVLGVTEEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLSTVIGCRDDIMVYLMHAGLQPKMAFTIMERVRKGLWLKISEDERNGYIQAMRDNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHYPIFYYCAYFSIRAKAFELRTMSAGLDAVKARMKDITEKRQRNEATNVENDLFTTLELVNEMLERGFKFGKLDLYRSHATDFIIEEDTLIPPFVAMEGLGENVAKQIVRAREDGEFLSKTELRKRGGVSSTLVEKFDEMGILGNLPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)

Length

1468 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

166.12 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M5 (strain Manfredo)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.739 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYENDKLIIAAPRFVNNDHFRKNHLPNLVKQLEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKAPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGVATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSDGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M28 (strain MGAS6180)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.662 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNSHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQDAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III polC-type

Organism

Streptococcus pyogenes serotype M3 (strain SSI-1)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.556 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTIDMVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGVWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVELHAHTNMSTMDALLTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKACPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGAEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III polC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.576 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTIDMVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYEPVDMDLHEDLCGLSDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M5 (strain Manfredo)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.739 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M28 (strain MGAS6180)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.662 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III polC-type

Organism

Streptococcus pyogenes serotype M3 (strain SSI-1)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.556 kDa

Sequence

Protein

DNA polymerase III polC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.576 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTIDMVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYEPVDMDLHEDLCGLSDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus mutans serotype c (strain ATCC 700610 / UA159)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

165.568 kDa

Sequence

MSELFKKLMDQIEMPLEMKNSRVFSSADIVEVKVYPESRIWDFRFSFETILPIDFYQELRSRLVTSFETADIKAVFDIEVENAEFSNELLQAYYQEAFKQPTCNSASFKSSFSHLTVSYTDGKVLISAPQFVNNDHFRKNHLPNLEKQFEAFGFGKLSFDIVSNQKMTEEIKHHFESSRQQQIQKASQETLEIQKSLEASIPPEEIPKPVSNFKERIKDRQAAFEKAEITPMAEIETEENRITFEGLVFDVERKTTRTGRHIINFKMTDYTSSFPMQKWAKDDEELKKYDMISKGAWLRVRGNIENNPFTKALTMNVQNVKTIVHKERKDLMPQGEKRVEFHAHTNMSTMDALPTVEQLVAKAAQFGHPAVAITDHGNVQSFPHGYHAGKKNGIKVLFGLEANLVEDRVPIVYNEVDMDMNEATYVVFDVETTGLSAINNDLIQIAASKMHKGNIVEQFDEFIDPGHPLSQFTTDLTGITDQHVKGAKPISQVLQEFQSFCQDTVLVAHNATFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLEHHHMANYDAEATGRLLFIFLKEAKEKHGVNNLLDLNTKIVDDNSYKKARVKHATIYVLNQKGLKNLFKLVSLSNVTYFAGVARIPRTILDQYRDGLLLGTACSDGEVFDTVLSKGVEDAVEVAKYYDFIEVMPPALYEPLLARELIKDEAGIQQIIKDLIEVGRRLDKPVLATGDVHYLEPEDEIYREIIVRSLGQGAMINRPIGRGENAQPAPLPKAHFRTTNEMLDEFAFLGEDLARDIVIKNPNEMVERFEDVEVVKTDLYTPFIENSEEKVAEMTYEKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYICPNPDCKHSEFITDGSVGSGYDLPDKICSECGTPYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEEYAFRAGTVGTVADRTAYGFVKGYERDYGKFYRDAEVDRLAQGSAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDLTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPKTIPADDPEVMKLFSGTEVLGVTEEEIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIATLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGAWLKISEEERNGYISAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMADISQKRKINQASNVEIDLFTTLEIVNEMLERGFKFGQLDLYRSDATEFIIDGDTLIPPFVALEGLGENVAKQIVKARNEGEFLSKTELRKRGGLSSTLVEKMSDMGILGSMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M1

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.668 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTIDMVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYEPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III polC-type

Organism

Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.556 kDa

Sequence

Protein

DNA polymerase III polC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.725 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKNFVSSRQALVEKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVEFHAHTNMSTMDALPTVESLIDMAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGIPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVERLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMSILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M18 (strain MGAS8232)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.742 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPRFVNNDHFRNNHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHNLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M12 (strain MGAS2096)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.64 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMSILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M12 (strain MGAS9429)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.64 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMSILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M2 (strain MGAS10270)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.652 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRKNHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVEKAVQDNLEAQKSLEAMMPPAEEATPAPKFDYKERVAQRQAGFEKAAITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVEFHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQDAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVGKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pyogenes serotype M4 (strain MGAS10750)

Length

1465 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.575 kDa

Sequence

MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKLVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGAEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus thermophilus (strain CNRZ 1066)

Length

1464 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.844 kDa

Sequence

MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNIFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEGAIEQLIRDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKEENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)

Length

1464 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.844 kDa

Sequence

MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNIFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEEAIEQLIRDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKGENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)

Length

1464 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.744 kDa

Sequence

MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNLFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEGAIEQLIKDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKGENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus thermophilus (strain CNRZ 1066)

Length

1464 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.844 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)

Length

1464 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.844 kDa

Sequence

MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNIFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEEAIEQLIRDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKGENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)

Length

1464 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.744 kDa

Sequence

MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNLFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEGAIEQLIKDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKGENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.741 kDa

Sequence

MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFHFVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGPCASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQVEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKAAAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSMQKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPEGERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKAGIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKMYKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVAHNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEHHHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKNQVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVDAAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGNVHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFLGEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPLPDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLGFDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERDYGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIEAMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLDLYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSSTLVEKMDEMGILGNMPEDNQLSLFDELF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.776 kDa

Sequence

MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFHFVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGPCASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQVEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKAAAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSMQKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPEGERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKAGIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKMYKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVAHNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEHHHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKNQVGLKNIFKLVSLSNTKYFEGVSRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVDAAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGNVHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFLGEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPLPDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLGFDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERDYGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIEAMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLDLYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSSTLVEKMDEMGILGNMPEDNQLSLFDELF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus suis (strain 98HAH33)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.109 kDa

Sequence

MSDKFQLLLQQIGMPLDARQSGAFSTATIEKVVLHKVSKLWEFTFRFETPLPLMDYQLFKARLATEFEKVGNKIQFSIVSDAEAFEAGLVEAYYPEAFTEDLCQSAGFKALFQPLEVAYRDGVLWIKGPETIDTDHFRKNHLPNLVEQYKRFGFGNLAVDIQVCQEMTQQQAEIFHAQNAEIYQQANEENLAALEQLAQMAPPPEAAQPFVPEYKKNRPAKVNIEKAEITPMIEVDSEENRIVFEGLVFEVEQKTTKTGRVIINFKMTDYTSSFTLQKWAKNEEEAQKFDMVKKGNWLRVRGNVETNNFTRDLTMNVQEVQEVKKEIRKDLMPEGEKRVEFHAHTNMSTMDALPAVEDLVARAAAWGHKAVAITDHGNVQSFPHGYHAARKAGIKPLFGMEANIVEDSVPIAYNEADVVLSDATYVVFDVETTGLSAVNNALIQIAASKMHKGNIIAEFDEFIDPGHPLSQFTTDLTGITDEHVRGSKPLEQVLREFQDFCQDSVMVAHNATFDVGFMNVNYERAGLPIISQPVIDTLEFARNLYPDFKRHGLGPLTKRFGVALEHHHMANYDAEATGRLLFIFLKDALEKHNLTNLNQLNTELIAEDSYKKARVKHATLYVINQVGLKNMFKLVSLSNTKYFEGVPRIPRTVLNAHREGLILGTACQEGEVFDDLLSKGIDEAVKTAAYYDFIEVMPPALYAPMIAKEQFKDMAEIEETIKQLIEVGRRAGLPVLATGNVHYIDPEEEIYREIIVRALGQGAPINWTIGNGENAQPAPLPKAHFRTTSEMLDEFAFLGESLAREIVITNPNAMLDRFEDVQVVKTDLYTPYIEKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVHRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPNCQHSEFITDGSYGSGFDLPDKDCEKCGTKYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEENAFRAGTVGTVAAKTAYGFVRGYERDYGKFYRDVEVERLAAGAAGVKRTTGQHPGGIIVFPDYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMVRKLQDLSGIDPQTIPADDKGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVEETKPTTFSELLQLSGLSHGTDVWLGNAQDLIKAGIANLSTVIGCRDDIMVYLMHAGLPPKMAFNIMERVRKGLWLKISEEERNGYIQAMKDNKVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPLYYYCAYFSIRAKAFDLATMSGGLERVKAKMEEIALKKKNNEASNVEQDLYTTLELVNEMLERGFKFGKLDLYKSHATDFLIEEDTLIPPFVAMDGLGENVAKQVVAARAEGEFLSKTELRKRGGLSGTLVEKMDEMGILGKMPEDNQLSLFDDLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus suis (strain 05ZYH33)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.109 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.741 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.776 kDa

Sequence

MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFHFVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGPCASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQVEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKAAAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSMQKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPEGERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKAGIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKMYKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVAHNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEHHHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKNQVGLKNIFKLVSLSNTKYFEGVSRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVDAAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGNVHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFLGEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPLPDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLGFDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERDYGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIEAMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLDLYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSSTLVEKMDEMGILGNMPEDNQLSLFDELF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus suis (strain 98HAH33)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.109 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus suis (strain 05ZYH33)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.109 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)

Length

1463 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.776 kDa

Sequence

MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFHFVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGPCASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQVEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKAAAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSMQKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPEGERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKAGIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKMYKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVAHNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEHHHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKNQVGLKNIFKLVSLSNTKYFEGVSRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVDAAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGNVHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFLGEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPLPDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLGFDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERDYGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIEAMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLDLYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSSTLVEKMDEMGILGNMPEDNQLSLFDELF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus sanguinis (strain SK36)

Length

1462 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.738 kDa

Sequence

MSNKFEILMNQLDMPLEMRNSEAFLNAEIEKVLVHKVSRVWEFHFSFANILPIEIFRELQKRLAQEFSKTGNQAVFEIHCQAPQVSDELLQAYYQLAFEEGPCASHGFKSLYQDLRVHLDGDKLLIEGASTIDTEHFRKNHLPNLSQQLVKYGFPQLTCLVQHSDELTQQQAENFQAENDKIVQAANEEALKAMESLQQMAPPPEEKPAYDFQARKAAAKPKLDKAEITPMIEVQTEENRLVFEGMVFDLEQKVTRTGRVLLNFKMTDYTSSFSLQKWMKNEEEAKKFDMIKKGAWLRVRGNVEMNNFTRDLTMNVQDVQAVTHYERKDLMPEGQKRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKAGIQLIYGMEANIVEDRVPIVYNEVDMELSDATYVVFDVETTGLSAVYNDLIQVAASKMHKGNIIAEFDEFINPGHPLSAFTTDLTGITDEHVRNAKPLEQVLKEFQEFCQDSVLVAHNATFDVGFMNVNYERHGLPKIIQPVIDTLEFARNLYPEYKRHGLGPLTKRFQIALEHHHMANYDAEATGRLLFIFIKDVAEKHGVTNLKDLNTDLVDENSYKKARVKHATIYVKNQTGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVYDAVVSQGVDAAVEVAKYYDFIEVMPPAIYEPLIAKEQIKDQEELQTIIRNLIEVGDRLGKPVLATGNVHYIEPEEEIYREIIVRSLGQGAMINRTIGHGENAQPAPLPKAHFRTTNEMLDEFAFLGEDLAKKLVITNPNQLAETFEPVEVVKGDLYTPFIDKAEETVAELTYQKAFEIYGNPLPDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGITEVNPLSPHYVCGKCQYSEFITDGSYGSGFDMPDKDCPECGHKLSKNGQDIPFETFLGFDGDKVPDIDLNFSGEDQPSAHLDVRDIFGSEYAFRAGTVGTVAAKTAYGFVKGYERDYGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNDIPMDDAGVMALFSGTDILGVTQEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIADLSTVIGCRDDIMVYLMHKGLDPKMAFTIMERVRKGLWLKISEEERNGYIAAMKENNVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFDIKTMSGGLDAVKRRMSEIAEKRKNNEASNVEIDLYTTLEIVNEMLERGFKFGKLDLYKSHATEFLIEGDTLIPPFSAMDGLGDNVARQVVRAREEGEFLSKTELRKRGGLSSTLVEKMDDMGILGNMPEDNQLSLFDEFF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Streptococcus sanguinis (strain SK36)

Length

1462 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.738 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Pyrococcus abyssi (strain GE5 / Orsay)

Length

1455 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

165.711 kDa

Sequence

MELPKEMEEYFEMLQREIDKAYEIAKKARAQGKDPSLDVEIPQATDMAGRVESLVGPPGVAKRIRELVKEYGKEIAALKIVDEIIEGKFGDLGSREKYAEQAVRTALAILTEGIVSAPIEGIANVKIKRNTWADNSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRAVTRLQYHPSPEEVRLAMRNIPIEITGEATDDVEVSHRDVPGVETNQLRGGAILVLAEGVLQKAKKLVKYIDKMGIEGWEWLKEFVEAKEKGEPKEEGKEESLAESTLEETKVEVDMGFYYSLYQKFKEEIAPSDKYAKEVIGGRPLFSDPSKPGGFRLRYGRSRASGFATWGINPATMILVDEFLAIGTQLKTERPGKGAVVTPVTTIEGPIVKLKDGSVLRVDDYNLALKVREDVEEILYLGDAVIAFGDFVENNQTLLPANYCEEWWILEFVKALKEIYEVHLEPFTENEEESIEEASDYLEIDPEFLKEMLRDPLRVKPPVELAIHFSEVLGIPLHPYYTLYWNSVEPKDVEKLWRLLKNYAEIEWSNFRGIKFAKKIVISQEKLGDSKRTLELLGLPHTVRDGNVIVDYPWAAALLTPLGNLNWEFMAKPLYATIDIINENNEIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGSSRDIKKAAEEGKVAEVEIAFFKCPKCGHVGPEHLCPNCGTRKELLWVCPRCNAEYPESQAEGYNYTCPKCNVKLRPYAKRKIRPSELLNRAMENVKVYGVDKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHFRPREIGVSVEKLRELGYTHDFEGKPLVSEDQIVELKPQDIILSKEAGRYLLKVAKFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRIIGFVDALVGYAHPYFHAAKRRNCFPGDTRILVQIDGVPQKITLRELYELFEDERYENMVYVRKKPKREIKVYSIDLETGKVVLTDIEDVIKAPATDHLIRFELEDGRSFETTVDHPVLVYENGRFIEKRAFEVKEGDKVLVSELELVEQSSSSQDNPKNENLGSPEHDQLLEIKNIKYVRANDDFVFSLNAKKYHNVIINENIVTHQCDGDEDAVMLLLDALLNFSRYYLPEKRGGKMDAPLVITTRLDPREVDSEVHNMDIVRYYPLEFYEATYELKSPKELVGVIERVEDRLGKPEMYYGLKFTHDTDDIALGPKMSLYKQLGDMEEKVRRQLEVAKRIRAVDEHGVAEKILNSHLIPDLRGNLRSFTRQEFRCVKCNTKFRRPPLNGKCPVCGGKIVLTVSKGAIEKYLGTAKMLVTEYNVKNYTRQRICLTERDIDSLFENVFPETQLTLIVNPNDICQRLVMARTGEVNKSGLLENLSNGSKKTEKAEKAEKPRKKSDEKPKKKRVISLEEFFSRKSK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)

Length

1451 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

167.5 kDa

Sequence

MVFNLENEKDKKVLALSNFLIDNNILDHNELNSLIERIESIYFNKYIEEKVFLFAITISRPLTIDIWNALYEGFNELNEGFKADNESFKLTITFKENEPFFKSKNSFSSVTIAIIKDYFHSFFSKDKKYKILIEQELSNPNFLSYENDELKAQCQTKELTEWLVQKSKSFIFWMNNAGFKNFNFIALYPIDKNESKLKVKAVTVSQYDKQFETKVFATEFIPIHKINQQIDDVKIIGQIFELKTHESLTGKKTLNIYVTDFQLGGSLILKWSYTDEKKIEGITIGNWIKAHIQVERDPNTQILYGIVREINPVEIPNNYKRLDLSKQKRVELVFHTKMTAFDGINDIEEYAQFAKERGWKAITVTDKDNIHIYPKFYEVAKKYDLKAIYGLEFNLTDDHIKIVHNPDNTKLSDATFVIFDIETTGLHGRYDDVIEFSARKIKNNSEIDHQQFFLKIDKPIPKTITEITKITDEMLEGGIDQQQGLEKIRNYLDDCVMVAHNGINFDLPFLQTQFEKYNIKPLTNPLIDTLCLSWALNPLFSSHTLSNICSKLKLEFDDERLHRAEYDTEALKKVFFYFKKQLKEMGINTLTEIDQNLNKKCQIDLMKRVFTNTAIVYVKNQRGFQNLYEMLSIALTDHNANRPLVLASSLAKFRKSFLLTENPVQGDIFKAALTKPINELEKAIEKVDFVLISQPNAYLGYTLREGLKKELINDAIKLVIKTATKLKKLVAVASDAYFIHPWENEYYKAIVCAKGLGGKWHRHFNNKEKEQTVPEVFLHTTDEMLKRMSFLGEDIAYKLVVENTNKIVKLLDLNELVPTKNKLYPPVMQDSNQKLIDKTWKQAEKRYGKNLPKLIKERIEKELNAIISNGFGIVFWISHLLVEQSVKDGYFVGPRGSIGSSLIANLIGISEINPLAAHYLCEQCHYFEVSDSVDDGYDLMIRDCPKCHEKASFKGDGHNIPFATFMGFSGDKIPDIDLNFSSEYQAKAHDYVRKLFGVNNTFRAGTIATVAEKTAYGYARNYFEIIKRVDLATTAEIERFKQKLIGIKRTTGQHPGGIMIFPSDHSVYEFTPCGFPADDVESEWKTTHFEYDALGDAILKLDILGQDDPTMLKHLADLTKINPQNIPHFDKNLISMFSSNKPLNLKPGIVDEVTGAVGIPEFGTKFVRKILEQTKPKDFADLIRVSGLSHGKNVWADNAQKLIKSNRLTLRDVIACRDDIMLYLINKGMQAKDAFEIMEKVRKGIKVNAKEVSLMQNCGVEQYWINACLKINYLFPKAHAAAYVLMAWRIAWFKLYHPLSYYACLLSFKLKEHDINGFEKGYEFIKNRLDELNKLYRIKKIKPKEAELLTSYEVYLEMMARNIKLQQISIQNSNARMFVEHNGVLIAPFITIPGMGEAVASSIVEARNEKPFASLNDFKKRTKITKKHVETMEQLQLFDEFEHQDDHKLFN

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Clostridium perfringens (strain 13 / Type A)

Length

1449 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

163.628 kDa

Sequence

MSNEFVKQINRSIKSDDNLNDLEFEITKFQLLKKSNTLRTIIKSKDQLSEEQKKIIKQYIKKAIGFEINIEIMYYIDISDITLKQVVDQHWNHVCEKIIEKHPVLKEVLLNSPIVIEGEKIIIKNGSEFLCTFVNKKHIDREIKGYIKSFFGINSLVEVKYDESLANKNYNDEKLNENKEIAKKVIETMKAQAAQEKPVKKESSDNKHKSNGGNKGGYEKKSYKDEPKNENTILGRNIQGDTIDISSIDMGSGIVTISGDVFKTDIFETKTGRIILTFFITDYTSSIAVKCFLRDKDKEHVLENVKKGLYCKVRGEATMDPYAKEVVIMARDINKLTKIERMDTAEEKRVELHMHTTMSSMDAVTAASKIVERAAKFGHKAVAITDHGVVQAFPDAQIAAKKNNIKVIYGVEGYLADNGTPIVINGHEESFDDEYVVFDIETTGFSSKNDKIIEIGAVKLKDGEIVDSFSTFVDPKVNIPYKITELTSITQNMVNGQPTIDEVLPKFMEFVGNSVLVAHNAAFDVGFIKKNLMDMGKTLKNPVMDTVPLARYLYPDLKKVKLNLVAKHLGISLENHHRAVDDAKATAEILKFSFKKMKEEMDIHDVKTLNEKYLSNIDVKKLPLHHIIILAKNQTGIKNLYKLVSMAHLDYFARRPRLPKSIITEYREGLIIGSACEAGQLYKAVLEGKTDGELKEIASFYDYLEIQPIQNNEFLIRKGNVKDEEELRELNRKIYDLGKEMDKPVVATCDCHFLDPNDEVFRRIIMAGQGYGDADNQPPLYFRTTNEMMKEFEYLGEEACREVVIENTQKIADMVEAVKPIPDETFPPKIEGAEEEIRNMTMNKVHSIYGENLPEVVQKRLDKELNSIINNGYAVLYLIAQKLVAKSLEDGYLVGSRGSVGSSFVATMSDITEVNGLPPHYVCPNCKKSEFFLDGSISSGADLPDKNCPDCGAKYIKDGHDIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGKGYVFKAGTIGTVAEKTAYGFVKKYLQERGLVVSQAEIERLTIGCTGIKRTSGQHPGGIMVVPNDNEIYNFCPIQHPADDVNTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGLDPKTIPLNDPKVISLFTSPDALGVTKEELGCEVGSYGLPEFGTKFVRQMLVDTQPKSFADLVRISGLSHGTDVWLNNAQYFIKEGYTTLKDCIATRDDIMVYLMYKDLPPKTAFTIMEKVRKGKGLSEEDEALMREKNVPDWYIESCKRIKYMFPKGHAVAYVMMAVRIAYYKVYYPEAYYTTYFTVRADDFDADLICKGEEAIKAKMEELNSLGNNISVKEKGLLTILEISYEMYKRGLNFLKVDLYKSEATKFKIEEDGIRPPLNALQGVGDNAAKSIVECRVNGEFISKEDLRLRSKVSKTVIETLDNHGCLEGMQESNQLSLFG

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactobacillus sakei subsp. sakei (strain 23K)

Length

1446 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

161.867 kDa

Sequence

MALDQTALFQKLLEQIALPADVAHYPGFKTGQVEQVIVHETSKRWTFKLHFDNVLPFAVYTAFEEHLEAAFQAIAAVSIEISTDAKELDGGVLAAYWEYVVNHSGIQSSLLHELCAKETPYIEGRKVLLVVENDIVKTFFINQAQTTIQAGYKRLGFPNFAIQPLIDESASQKSIEDFQAKRAVQDAERAQAAAEAIKKNEALKEKRKTEGKPVDGPIVMGRGINPAEPVRQMISITEEERSIVIEGFIFDKEVRVLRSGRQLLILKMTDYSSSFTVKKFSRDASDESLFAAIDKGMWFKVRGSVQEDNFMRDLTVNANDLVEVSHPKREDTATDGKRIEMHLHTNMSQMDATNPIGDYVKQAAKWGQPAIAVTDHYNLQAFPDAYAAGKKNGVKILYGVEVNLVNDGTPVVYNLRDQVLESAEYVIFDVETTGLSAVYDSIIELAAVKMRDGEVVASFDEFIDPERPLSAFTTQLTSITNEMVHGAKKEAEVLAMFKEFTGDAVLAGHNVSFDMGFLNAGYERNDIDLIDNPVIDTLELSRMLHPEYKNHKLDSLTKRYKINLEHHHRANADAESTGYLLYKLEKEAAENYDMVNVNQLNDRVGVGEFYKQARPAHAVLMAQTQAGLKNLFKLVSASMTEYYYRTPRLPKSKLDALREGILVGSACSNGEVFEAMMQKGYNEALDRAKYYDYIEVMPKAVYAPLLERELVRDNRALEEIIRNLVKVGEKLNKPVVATGDAHYLNPEDAIYRKILIHSMGGANPLNRSKLPDVHFRSTDEMLTAFDFLGPELAQELVVANPQKIADQIDEIVPVKDKLYTPKMAGAEDEIQTLTMNRAHELYGAELPEIVEARLKKELKSIIGNGFSVIYLISQKLVYKSGKDGYLVGSRGSVGSSLVATMTGITEVNPLPPHYRCSNCHYSEFFTKGEVGSGYDLADKDCPECGTPLDKDGHDIPFETFLGFHGDKVPDIDLNFSGDYQPVAHNYTKVLFGENNVFRAGTIGTVADKTAYGYVKAYERDTEQTFRGAEVDRLAKGSTGVKRTTGQHPAGIIVVPDYMDIYDFTPIQFPADDQDAAWKTTHFDFHSIHDNILKLDILGHDDPTMIRMLQDLSGIDPKSIPTDDPGVMALFSGTDSLGVTPEQINSKMGTLGVPEFGTRFVRGMLEETHPTTFSELLQISGLSHGTDVWLGNAEELINKGVVTLKDVIGCRDNIMMDLIHWGMDDSMSFNIMERVRKGKGIPDDWQQAMRDNENVPDWYIDSCLKIKYMFPKAHATAYILMALRIAYFKVYFPIIYYCAYFSVRASDFDLVAMAQGKEGVKARMKEITDKGMEASTKEKNLLTVLEIANECLERGITIKMVDIEKSDSSDFLIQDDHTLLAPFRAVPSLGDNVAKQIVSAREEKPFLSKEDLSNRGKVSKTLIEYLTENNVLNDLPDENQLSLFDMM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactobacillus brevis (strain ATCC 367 / JCM 1170)

Length

1445 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

161.76 kDa

Sequence

MDEDRHALFEKLLQQLDLTSEADQPYFQTATVDRLTVHEQSRRWQFLLKLPSMLPFTAFVDFHNHLQVAFREIATVEATIEVDQPELTNRLLGDYWEWIVKNSGLTSNLIQELCQSQVPELDENNRVLLYAQNEVVKDFLSNQALGPIESAYRRAGFPKFNIHVMIDESKSQAKIDEFKARQEKTDAQLAQQAAAAIEKANQKRQSQGDTPAAEGPTQIGKAIKGDQPVTKMIDITQEERSVVVEGYVFEKEVRKLRSGRQLLTLKITDYTSSFAVKKFSRGAEDEAQFAGVEEGSWVKVRGNVQEDTYMHDLALNAYDINQVKHASRQDTAPEGEKRVELHLHTSMSQMDATNSIGDYVKQAKKWGMPALAITDHADVQGFPAAFNSAAKAGIKMLYGVEANLVDDGVPIGYNSAHVPLDGATYVVFDVETTGLSAIYDKVIELSAVKMEHQNVVDQFEEFIDPGFPLSEQTTNLTSITDDMVAGSKSEEEVFKLFREFCGDAIIVGHNVTFDVGFMNTGYQRHGMAEISNPIIDTLTLARFLYPTLKSYRLNTLAKRFHVSLEHHHRAVYDAESTGHLNYLFLKDAEDRYDIQYHDQLNDHMTDNDAYKHARPNHAILLAKTQAGLKNMFKLVSASNVDYYYRVPRVPRSVLEEYREGIIVGSACSSGEVFTAMMQKGQVEAAAKAKFYDYLEVQPSAAYQPLIDSGLIADRENMEEIVRNMVKLGHDLNKPVVATGDVHFLNPDDYIYRKILIHSQGGANPLNRQELPDVHFMTTDEMLTDFAYLGEETAKEIVVTNTQKIADDIDEVHPLKDKLYTPRMEGAEDEIRQRTMDTAHAMYGDPLPELVQHRVDRELKSIIGNGFSVIYLIAQRLVAKSNKDGYLVGSRGSVGSSLVATLTGITEVNPLPPHYRCPKCQYSHFYTKGEYSSGYDLPEKDCPECGTLMIGDGHNIPFETFLGFKGNKVPDIDLNFSGDYQPIAHNYTKVLFGEKNVYRAGTIGTVADKTAYGYVKAYERDTEQTFRGAEIDRLAKGATGVKRTTGQHPAGIIVVPDYMDIFDFTPIQYPADDQSAAWQTTHFDFHSIHDNILKIDILGHDDPTMIRTLQDLSGVDPTTIPMDDPGVMGLFSGTDSLGVTPEQIQSKTGTLGVPEFGTRFVRGMLEETHPQNYSQLLQISGLSHGTDVWLGNAEELIKNGTATIANVIGCRDNIMTDLINFGLDSETSFQVMEHVRKGRGIPDEWQEKMKATDCPDWYIDSCLKIKYMFPRAHAAAYVLMALRVAYFKVYFPIIYYAAYFSVRADDFDVVAMSQGKTAVKAAMKAINDQGMDASAKDKNLLTVLELANEMLERGFKFKMIDLEKSDAADWIIDGDTLIAPFKAAPGLGLNVAKQIVAARNDRPFISKEDLAKRGKVSKTLIDFMTENGVLAGLPDENQLSLFDDLM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441)

Length

1444 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

161.523 kDa

Sequence

MALSQHEMFEKLLDQLDLAADVRQDPSLTSGTVQNVTIHEQSRRYDFTLGFDAILPFQTFNAIATKLPLVFQQIAATDLSVVVTQPTITDELLAQYWQYVVTHAEIGTGIVRELCEKQVPTLENDRAVIKTENEQIRQYLIQQGLGKLEETYRQVGFSGLRMQAEVDEEQAAQSMAAFQAQRAEETAKMAKAAAEVVKQQAAKQKQVQTDGPVQMGRQMKMTDAPQQMVTITQEERSVTVEGYVFDVEVRELRSKRQLLIFKVTDYSSSFIAKKFSNGPEDEAMFARIQKGQWLRVRGSVQEDNYSRELTINAQDIQTVSHPDPTDDAEGEKRVELHLHTNMSQMDAMNPISDYVKRAKEWGHKAIAVTDHAGLQAYPEAHSAAVKAGLKMLYGVEINLVDDGTPVAYRADEPRDLASAEYVVFDVETTGLSAVYDKVIELAAVKMKDGKVIDQFEEMIDPGFPLSELTINLTHITDDMVHGSKSEVDVFKLFQQFCDGAIMVGHNVTFDVGFLDNGYERHGLADIDNPVIDTLELSRMLHPERKNHKLDTLAKQYKVSLEHHHRANADAEATGYLLYALEKEAAKMYGMTTLNQLNDRVGAGDAYKAARPSHAIVFAKTQAGLKNLFKLVSLSNVKYFYRVPRVPRSQLQKLREGLLVGSACSNGEVFTAMMQKGEAEARAKASFYDYLEVQPLPVYQPLIEAGLIKGEAHLKDIIQKIIKIGSELEKPVVATGDAHYLDQHDAIYRQILIHSQGGANPLNRHSLPDVHFRSTSEMLTDFSWLGEEKAHELVVDNSNLIANWVDDDITPVKDKLYTPEVPGVEENLKHDVMTTAHELYGDPLPDIVAQRLDKELKSIIGNGFSVIYNIAQRLVLKSNKDGYLVGSRGSVGSSLAATMAGITEVNPLPPHYRCPNCQYSEFFTHGEIGSGFDLPDKQCPKCGADLHKDGHDIPFETFLGFHGDKVPDIDLNFSGDYQPIAHNYIKVMFGEDHSFRAGTIGTVADKTAYGYVKAYERDTGQQLRGAEIDRLAQGDTGVKRTTGQHPAGILIVPADMDIYDFTPIQYPADDQNAAWMTTHFDFHSIHDNILKMDVLGHDDPTMIRMLQDLSGVEPKSIPTDDPGVMALFSGTKSLGVTPEQINSKMGTLGIPEFGTRFVRGMLEETKPTTFSELLQISGLSHGTDVWLGNAEELIKQGIVTLKEVIGCRDNIMMDLIHWGMEDSMAFNIMEHVRKGRGIPDDWQKAMRENENVPDWYIESCLKIKYMFPKAHATAYILMALRIAWFKVHYPLIYYTAYFSVRAEDFDLAAMSHGKEAVKAAMKEITDKGMDASTKEKQLLTVLEIANECLERGFKIKMIDVTKSDSHNFLIQDDHTILAPFRAVPGLGDNVAKQIVAAREEKPFLSKEDLANRGKVSKTLIDYMTTNHVLDDLPDENQLSLFDGLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactobacillus salivarius (strain UCC118)

Length

1444 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

164.253 kDa

Sequence

METNKQDLFKKLLRQINWENKHGFEEVFTNAEIQKVEVHVESKVWNFHLQIEDILPYEVFYQFYQQLQLAFKDIAKVDITLHTKNPIITNQKLGDYWKWVVFNSGIQSSFIQELSRSKVPYLDNNRVILLAENEIVKRFLVDQALGPLESTYHKIGFPKFSVNTLVDETKAQEIIENIKEQKAKSDAELAQKAVEAIKKQSEQREKSKAEVPSIEGPVQLGKKISPDQEITQMINITEEERSVTVQGYVFDKEVRELRSGRKLLILEVTDYTASFVVKKFSRTEEDEAMFDAINSGVWIKVRGSVQEDNYMRDLVINAYDLNEIKHESRKDTAPENEKRVELHLHSNMSMMDATNSITEYVSKAAEWGHKAIAITDHGTLQAFPEAHAAGQKNNVKILYGVEANIVDDGVPIAYNEQHKNLRDATYVIFDTETTGLSAQYDKVIELAAVKMEKGNVIDTFEEFIDPGHPLSQTTINLTSITDDMVRGSKSEEEVFRLFKEFCKDCIIVGHNATFDVDFMNTGYERHNMEMIQEPWIDTLPLARYLYPEMKGFRLNTLAKKLNIKLEHHHRAIYDAEATGFIYYAMLKDAEEKQILYHDDFNKHVGENDAYKHEHPSHAIILAKTQEGLKNLFKLTSESMVKYFYRVPRVPRSILEKYREGLIVGSACADGEVFTAMMQKGYTIAKQKAEFYDYLEVQPKPLYEPLLEQELVKDNDNLEEIITNMVKLAHELDKPIVATGDVHFMNKEDAIYRKILIHSQAGANPLNRLKKLPDAHFRTTDEMLEEFSFLGEDIAKEIVVTNPNKLVDEISEITPVKDKLYTPKMEGAEQDIHDLTMNRAHAWYGDTLPEIVQKRLDKELKSVIGNGFSVIYLISQKLVYKSNKDGYLVGSRGSVGSSLVATMTGITEVNPLPPHYRCPKCKWTHFYEKGEYGSGYDLPDKDCPNCGTELIKDGQDIPFETFLGFKGNKVPDIDLNFSGDYQPIAHNYTKVLFGENNVYRAGTIGTVADKTAYGYVKAYERDTEQNFRGAEIDRLAKGATGVKRTTGQHPAGILVVPDYMDIYDFTPIQYPADDLTAAWRTTHFDFHSIHDNILKLDILGHDDPTMIRMLQDLSGIDPKTIPTDDPGVMALFSGTDILGVTPEEIQSSTGTLGVPEFGTRFVRGMLEETHPKTFAELLKISGLSHGTDVWLGNAEELIKNGTVTMPDVIGCRDDIMMDLIHMGVESDKAFKIMEHVRKGRGIPDEWQADMRAADVPEWYIGACLKIKYMFPKAHAAAYVLMALRIAYFKVYYPLVYYAAYFSVRADDFDLVSMSRGKEAVKNAMELINSKGNEATTKEKNLLTVLEIANEMLERGFDFSMVDINKSDAQNWTIQEDGRTLLAPFTAIPGLGLNVAKQIVAAREEQEFISKEDLSKRGKVSQSLIDFMTENHVLDDLPDENQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)

Length

1444 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.905 kDa

Sequence

MTAKEEEKQERFQLLMTQIGLQDVTTYEEFTKDAKIEKLVADKKNKTWQFHLHVPQIFPAALFHMMDVGMKRAFSQIAETEMQIVPENQTINETLIQEYWNLIVEPIGKQSPMIGKLLMEQKPTFKEPHFIEVAVHNDMEEATIQQRFQAKIIENYGKAGFPRLAMKMHMLDQSETDEYKAFAQAKQEEDQKKAAEAVQVMQKRQAEGQNGSANAAPLTGPFQIGYKIKDDEEIKRLGDVYDEERRITVQGLIFATEIRELRSGRSLLQFKITDYTSSMIIKMFSRDNEDAAMFQNLKKGMWVKVRGSVQNDTFVRDLIMMAQDINEIAGVKRLDTAEEKRAELHLHSPMSQMDATSSVDSLFKQAADWGHKAIAITDHSVAQSFPEAYGAGQKYGLKVIFGIEANLIDDGVPIAYNDQHIALEDATYCVFDVETTGLSAVYDTIIELAGVKMKNGEIIDKFEAFIDPGHPLSATTINLTGITDDMVKGSDPIDVVLKQFREWSGDDILVAHNASFDMGFINTAYEKVGLEKAKNAVVDTLELARFLYPHFKNHRLNTLTKKFNIILEQHHRAVFDAEATAYLAWKLIKDAKEMHDIEFHDSLNDYMGEGDAYKRARPFHATIYAQTDVGLKNLFKLITMSNINYFYRVPRIPRSQLKKMREGLIIGTACSQGELFEAMMQKGMQAAEKVAEFYDFIEVQPKPVYAPLIERELVRDEKALEEILKNIVRVGEKTGKPVVATGNVHYKDPVDKIYRKILIHSQGGANPLNRAELPDVHFRSTDEMLKEFAFLGEEKAKEIVVTNSNLVVDWMDDLKPIKDELYTPKIDGAEDEVRNMSYGMAHQLYGEKLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYLCPNCKDSEFFDDGSVGSGFDLPDKDCPHCGTPYQKEGQDIPFETFLGFKGDKVPDIDLNFSGDYQPVAHAYTKEIFGEDYVFRAGTIGTVAEKTAFGYVRNYERDMNMTIRGAEVDRLVAGCTGVKRTTGQHPGGIIVIPDYMDVYDFTPVQFPADATDSEWKTTHFDFHSIHDNVLKLDILGHDDPTAIRMLQDLSGIDPKTIPTDDPDVMKLFGSTESLGVKPADIDSKTGTLGIPEFGTRFVRQMLEQTKPTTFSELVQISGLSHGTDVWLGNAEELIKNKTCELPDVIGCRDDIMVFLIYQGLESSLAFKIMESVRKGKGLTEEMEEAMIANKVPLWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYFYATYFTVRADDFDLTSMVNGKEAVKATMKEVNDKGMEASTKEKNLLTVLEIANEMLARGFHFQKVDLYKSSADEFIIDGDSLIPPFNAIPSLGTNVAKQIVAARENGEFLSKEDLQQRGKVSKTIIQYMDDQGCLEGLPDQNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Listeria monocytogenes serotype 4b (strain F2365)

Length

1444 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.742 kDa

Sequence

MTAKEEEKQERFQLLMTQIGLQDVTTYEEFTKDAKIEKLVADKKNKTWQFHLHVPQIFPAALFHMMDVGMKRAFSQIAETEMQIVPENQTIDETLIQDYWNLIVEPIGKQSPMIGKLLMEQKPTFKEPHFIEVAVHNDMEEATIQQRFQTKIIESYGKAGFPRLAMKMHLLDQSETEEYKAFALAKQEEDQKKAAEAVQVMQKRQAEGQSGGGGAAPLTGPFQIGYKIKDDEEVKRLGDIYDEERRITVQGLIFATEIRELRSGRSLLQFKITDYTSSMIIKMFSRDNEDAAMFQNLKKGMWVKVRGSVQNDTFVRDLIMMAQDVNEIAGVKRLDTAEEKRAELHLHSPMSQMDATSSVDSLFKQAADWGHKAIAITDHSVAQSFPEAYGAGQKYGLKVIFGIEANLIDDGVPIAYNDQHIALEDATYCVFDVETTGLSAVYDTIIELAGVKMKNGEIIDKFEAFIDPGHPLSATTINLTGITDDMVKGSDPIDVVLKRFKEWSGDDILVAHNASFDMGFINTAYEKVGLEKAENAVVDTLELARFLYPHFKNHRLNTLTKKFNIILEQHHRAVFDAEATAYLAWKLIKDAKEMHNIDFHDSLNDYMGEGDAYKRARPFHATIYAQTAVGLKNLFKLITMSNINYFYRVPRIPRSQLKKLREGLIIGTACSQGELFEAMMQKGMQAAEKVAEFYDFIEVQPKPVYAPLIERELVRDEKALEEILKNIVRVGEKTGKPVVATGNVHYKDPVDKIYRKILIHSQGGANPLNRAELPDVHFRTTDEMLKEFAFLGEEKAKEIVVTNANLVVDWMEDLKPIKDELYTPKIDGAEDEVRNMSYAMAHQLYGEKLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYLCPNCKDSEFFDDGSVGSGFDLPDKDCPHCGTPYQKEGQDIPFETFLGFKGDKVPDIDLNFSGDYQPVAHAYTKEIFGEDYVFRAGTIGTVAEKTAFGYVRNYERDMNMTIRGAEIDRLVAGCTGVKRTTGQHPGGIIVIPDYMDVYDFTPVQFPADATDSEWKTTHFDFHSIHDNVLKLDILGHDDPTAIRMLQDLSGIDPKTIPTDDPDVMKLFGSTESLGVKPADIDSKTGTLGIPEFGTRFVRQMLEQTKPTTFSELVQISGLSHGTDVWLGNAEELIKNKTCELPDVIGCRDDIMVFLIYQGLESSLAFKIMESVRKGKGLTEEMEEAMMANKVPLWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHYPLYFYATYFTVRADDFDLTSMVNGKEAVKATMKEVNDKGMEASTKEKNLLTVLEIANEMLARGFHFQKVDLYKSSADEFIIDGDSLIPPFNAIPSLGTNVAKQIVAARENGEFLSKEDLQQRGKVSKTIIQYMDDQGCLEGLPDQNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

Length

1444 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.733 kDa

Sequence

MTAKEEEKQERFQLLMTQIGLQDVTTYEEFTKDAKIEKLVADKKNKTWQFHLHVPQIFPAALFHMMDVGMKRAFSQIAETEMQIVPENQTINETLIQDYWNLIVEPIGKQSPMIGKLLMEQKPTFKEPHFIEVAVHNDMEEATIQQRFQTKIIESYGKAGFPRLAMKMHMLDQSETDEYKAFAQAKQEEDQKKAAEAVQVMQKRQAEGQSGGGGAAPLTGPFQIGYKIKDDEEVKRLGDIYDEERRITVQGLIFATEIRELRSGRSLLQFKITDYTSSMIIKMFSRDNEDAAMFQNLKKGMWVKVRGSVQNDTFVRDLIMMAQDVNEIAGVKRLDTAEEKRAELHLHSPMSQMDATSSVDSLFKQAADWGHKAIAITDHSVAQSFPEAYGAGQKYGLKVIFGIEANLIDDGVPIAYNDQHIALEDATYCVFDVETTGLSAVYDTIIELAGVKMKNGEIIDKFEAFIDPGHPLSATTINLTGITDDMVKGSDPIDVVLKRFKEWSGDDILVAHNASFDMGFINTAYEKVGLEKAENAVVDTLELARFLYPHFKNHRLNTLTKKFNIILEQHHRAVFDAEATAYLAWKLIKDAKEMHNIDFHDSLNDYMGEGDAYKRARPFHATIYAQTAVGLKNLFKLITMSNINYFYRVPRIPRSQLKKLREGLIIGTACSQGELFEAMMQKGMQAAEKVAEFYDFIEVQPKPVYAPLIERELVRDEKALEEILKNIVRVGEKTGKPVVATGNVHYKDPVDKIYRKILIHSQGGANPLNRAELPDVHFRTTDEMLKEFAFLGEEKAKEIVVTNANLVVDWMENLKPIKDELYTPKIDGAEDEVRNMSYAMAHQLYGEKLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYLCPNCKDSEFFDDGSVGSGFDLPDKDCPHCGTAYQKEGQDIPFETFLGFKGDKVPDIDLNFSGDYQPVAHAYTKEIFGEDYVFRAGTIGTVAEKTAFGYVRNYERDMNMTIRGAEIDRLVAGCTGVKRTTGQHPGGIIVIPDYMDVYDFTPVQFPADATDSEWKTTHFDFHSIHDNVLKLDILGHDDPTAIRMLQDLSGIDPKTIPTDDPDVMKLFGSTESLGVKPADIDSKTGTLGIPEFGTRFVRQMLEQTKPTTFSELVQISGLSHGTDVWLGNAEELIKNKTCELPDVIGCRDDIMVFLIYQGLESSLAFKIMESVRKGKGLTDEMEEAMMANKVPLWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHYPLYFYATYFTVRADDFDLTSMVNGKEAVKATMKEVNDKGMEASTKEKNLLTVLEIANEMLARGFHFQKVDLYKSSADEFIIDGESLIPPFNAIPSLGTNVAKQIVAARENGEFLSKEDLQQRGKVSKTIIQYMDDQGCLEGLPDQNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)

Length

1444 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.974 kDa

Sequence

MTAKEEEKQERFQLLMTQIGLQDVTTYEEFTKDAKIEKLIADKKNKTWQFHLHVPQIFPAPLFHMMDVGMKRAFSQIAETEMQIVPENQTINETLIQEYWNLIVEPIGKQSPMIGKLLMEQKPTFKEPHFIEVAVHNDMEEATIQQRFQAKIIENYGKAGFPRLAMKMHMLDQSESDEYKAFAQAKQEEDQKKAAEAVQVMQKRQAEGQNGNSSAAPLSGPFQIGYKIKDDEEIKRLGDVYDEERRITVQGLIFATEIRELRSGRSLLQFKITDYTSSMIIKMFSRDNEDAAMFQNLKKGMWVKVRGSVQNDTFVRDLIMMAQDINEIAGVKRLDTAEEKRAELHLHSPMSQMDATSSVDSLFKQAADWGHKAIAITDHSVAQSFPEAYGAGQKYGLKVIFGIEANLIDDGVPIAYNDQHIGLQDATYCVFDVETTGLSAVYDTIIELAGVKMKNGEIIDKFEAFIDPGHPLSATTINLTGITDDMVKGSDPIDVVLKRFKEWSGDDILVAHNASFDMGFINTAYEKVGLEKADNAVVDTLELARFLYPHFKNHRLNTLTKKFNIILEQHHRAVFDAEATAYLAWKLIKDAKEMHDINFHDSLNDYMGEGDAYKRARPFHATIYAQTDVGLKNLFKLITMSNINYFYRVPRIPRSQLKKLREGLIVGTACSQGELFEAMMQKGMQAAEKVVEFYDFIEIQPKPVYAPLIERELVRDEKALEEILKNIVRVGEKAGKPVVATGNVHYKDPVDKIYRKILIHSQGGANPLNRAELPDVHFRSTDEMLKEFAFLGEEKAKEVVVTNSNLVVDWMEELKPIKDELYTPKIDGAEDEVRNMSYDMAHQLYGENLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYLCPNCKDSEFFDDGSVGSGFDLPDKECPHCGTAYQKEGQDIPFETFLGFKGDKVPDIDLNFSGDYQPVAHAYTKEIFGEDYVFRAGTIGTVAEKTAFGYVRNYERDMNMTIRGAEIDRLVAGCTGVKRTTGQHPGGIIVIPDYMDVYDFTPVQFPADATDSEWKTTHFDFHSIHDNVLKLDILGHDDPTAIRMLQDLSGIDPKTIPTDDPDVMKLFGSTESLGVKPADIDSKTGTLGIPEFGTRFVRQMLEQTKPTTFSELVQISGLSHGTDVWLGNAEELIKNKTCELPDVIGCRDDIMVFLIYQGLESSLAFKIMESVRKGKGLTEEMEEAMMANKVPLWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHYPLYFYATYFTVRADDFDLTSMVNGKEAVKATMKEVNDKGMEASTKEKNLLTVLEIANEMLARGFHFQKVDLYKSSADEFIIDGDSLIPPFNAIPSLGTNVAKQIVAARENGEFLSKEDLQQRGKVSKTIIQYMDDQGCLEGLPDQNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactobacillus reuteri (strain DSM 20016)

Length

1443 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

163.272 kDa

Sequence

MGLSRQELFGKLLEQIHFPEKDNSAFRNAAVQSVVVHKKSRQWEFHLIFNKALPYDLFTQFNQSLQLGFKDIAKVSLKISTPMTELDESQIANYWQFIINKAISDTPMLQQACLQTAPEVKDGRVTLVVENEVIKDLLAQKALDKIEKSYQELGFPKFRIHPFVDQSASQAKIEELKAKHEKADAALAAKAAARIKKNEAAKKTAKKSAPVAPADGPVQLGRMIDSKQNVIQMKDIEGEERSVVVEGYVFNAEIRELRSGRQLLTFEITDYTSSFSVKKFSRNSDEEAQFANIKAGMWLKVRGPVQEDTWMRDLVITAYDVNEVTHIARQDKAPQDDKRVELHTHTTMSQMDATNSITELATRAHKWGHPAIAVTDHGNVQAFPEAFSVAQKTGIKMLYGMEANVVDDGIPLVYNENHEELAHQTYVIFDVETTGLSAIYDKVIELSAVKMQDGNVLERFDEFIDPGFPLSEQTTNLTSITTEMVQGSKTEEEVFQMFKDFCKGCIIAGHNVSFDMGFMNTGYERHQMGKIAEPVIDTLPLARFLYPDMRGYRLNTLSKKFKVALEHHHRANYDSEATGHLLYKFLKDAEARYDVKYVDDLNKHMEENNAYRHARPFHVTIFAQTQAGLKNLFKLVSLSNVEYFYRVPRIPRTVLTKYREGLLLGTACSSGEVFTAMMEKGYDQALEKARYYDFIEVQPKPNYAPLLEQHVIADEGHLEDILKNMVKLGDELEKTVVATGDVHYLDPHDGIYRKILINSQGGANPLNRTERPEVHFRTTDEMLNEFAFLGEEKAHELVVENSNKIAAEIDDNIRPVKDKLYPPHMKGAEQEIQDRTWNTARKWYGDPLPQLVQDRIELELNSIVKNGFSVHYLIAQRLVAKSNKDGYLVGSRGSVGSSVVATLSGITEVNPLPPHYRCPNCQFTHFYTQGEYSSGFDLPDKKCPKCGTLMVKDGHDIPFQTFLGFKGNKVPDIDLNFSGDYQPIAHNYMKVLFGEKNVFRAGTIGTVADKTAYGYVKAYERDTEKEFRKAEEDRLAKGATGVKRTTGQHPAGIIIVPDDMDIYDFTPVQYPADDQTAAWETTHFDFHSIHDNILKMDILGHDDPTMIRALQDLSGIDPQSIPMDDPGVMALFSSPKVLGVTEEQIQSKTGTLGLPEFGTRFVRGMLEDTHPKNYSQLLQISGLSHGTGVWLDNAQELIKQGIATIANVIGCRDNIMTDLIHYGMDSEISFQIMEHVRKGRGIPDEWQEKMHEANVPQWYMDSCLKIKYMFPRAHAAAYVLMALRIAYFKVYFPLVYYCAFFSVRADDFDVVAMSHGKDAVKQRMKEINDKGNDASAKEKNLLTILELANEMLERGFKFKMVDIEKSDASDWLIDGDSLIAPFRAVPGLGLNVAKQIVAAREERPFLSKEDLAERGKVSQTLIDFLTDNHVLDKLPDENQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129)

Length

1443 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

165.102 kDa

Sequence

MVFDTETEKGKRIWALSQFLVKKNILDHNELHQLNNRIELVYLENDRENALFLVALTLKKPLTIDIWNALYEGFQDAEGAELRITFQEDATFFKDGSTKSSVTLAIIKDYFKSFFGKDKKYRILLEQELTHPNFLSYSNHELKANCQSQELDQWLIEQRQAFIKWMHQAGFTHFGFVSLFNPPAEKQLKVKSMKVSKYDKQFETEVFSTEFVPIHKINQQMDEIKLMGQIFELKDFPGYNNLRNTLNIYVTDFQLGGSLILKWFYKDPKTIEGIKIGTWVKATVKVERDAKTQLLQGIIKEISPIETPAYYRRPDQDKQKRVELVFHTKMSAFDGINSVQEYAQFAKERDWKTIAVTDKDNIHIYPTLYEVAKKYGLKAIYGLECNLIDDHIKIVSNPDKTKLKDATFVIFDIETTGLHGRYDSVIEFAGIKVKHNREVERMQFFLKIDGPLPAAVTEITKITQAQLEDGMEQQAGLEKLRAWLDGCVMVAHNGLSFDLPFLQTQFEKYNIAPLTNPLIDTLALSWALNPGFASHTLSNICAKLKFDFDDERLHRADYDTQALKKVFDYFKEQVELMGITNLEQLDQELNQQCHFELLKRTFTNTGIIYIKSQSGFAKLYELLSIALTDNNATRPLVLTSTLQKFAKSFVITDNPVQGDIFKAALTKPLKELEAAIKRVDFVLIAPPGAYAGYTIREGLKKEAIPNAIKLVVDTAQRLNKLVAVASDAYFIHPWENEYYKAIVCAKGLGGRWHRHFNYKEREQRVPNVFVRTTGEMLNEMSFLGEQLAYELVVENTNKLAKQLTADDLVPVQTKLQPPVIEGSNENLAAKTWSQAKAIYGDPLPKLIEQRIQEELKAIIDNGFGIIYWISHLLVKQSVQDGYFVGPRGSIGSSLVANLIGISEINPLVPHYLCESCQYFEVNEEVDDGYDLMVRDCPKCGAKAAFKGDGHNIPFATFMGFAGDKIPDIDLNFSSEYQAKAHAYVRELFGEQYTFRAGTIATVAEKTAYGYARNYFEIIKQTELATAPEIERFKQKLVGIKRTTGQHPGGIMIFPNHKSVYEFTPCGYPADDTSSDWKTTHFEYDALGNTILKLDILGQDDPTMLKHLGDLTHVNPQNIPRFDKKLTEMFWSVNPLKLKPHYLDEPTGAIGIPEFGTKFVRKILEQTKPKGFGDLIRVSGLSHGKNVWADNAQKILKDQNLSLKDVIACRDDIMLYLIHKGMQAKDAFEIMEKVRKGIALNAKEVQLMQSNGVEQHWINSCLKISYLFPKAHAAAYVLMAWRIAWFKLYHPLSYYACLLSFKLKEHDVSGFKSGVSFVKQKLEELNTLYRIKRIKPKEAELLTSYEVYLEMMARGIKLEQISLTHSHATRFVEHNGMLIAPFITIPGMGEAVANSIIEARNEKPFSSLDDFKKRTKITKKHIEAFTQMQLLDEFREQDNQKKLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Ureaplasma parvum serovar 3 (strain ATCC 700970)

Length

1442 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

166.229 kDa

Sequence

METKNALFKKIVKISDQLLNKISIKKLTKDKKNNLFVYFDEFVDVTIIDELHQLSKTTLMHDLQIWYINNLKEVDHKKILTFFKKISEQNANLIFLEQINDLNTKIEYNSNLNSLILKINDKLIYDHFIANKLEILNILKVWSLPYSNFEIHFENLSSLLNEKHEQAVNEIISHHIQQQKHLEQQISQQQNFYNNQKANFNYYKNPSNKTITKLIDINPLMNNAKIRAYVFLKKIDILKSGAIAYKLNVIDDSETLTIMTYLPSGEHPLKKFLDELKIDQLIEAEIDIVLDNMSKSGQVPIGKIKKICCVEDKHVKKQITPRLELNFHTKMSSLDAIISTQELIDFAVKNQLKTIGITDRNVVQAYPEIAKFSKKQDLKIIYGLETEELEDQIPLVLNVRDQNLDNATYVIFDIETTGLFPNFDEIIEFGAVIMQNNKQIGEKIQFFIKPIQQINENVTNLTNISQEMVNNAIDEKTALLKIKEIFDDHILVAHNGINFDINFINQRLLKWGLEPLKNPSIDTLMISRAINPFKSHRLGAICKKYEVDYNDESAHRADYDAIVLADVFKVMKNNLFNDFGITNLSEINTKLQTTMLKNRSFGNWINLYIKNQANVKDMYELVSISHTDMYYTRPTITTSFLANKKDKLIISNSIHESDLINALYSKNDEEIKRLIQRYDFITLPSLGSQKHLVYAKKITIENVQKAFKKLIYLALELNKIIIYSSSPYYFFKDDKKFYDVYVNTKGLEGKAHRFANEVYVPDLEYIDQKNAIDELAYLEDEKLINLIINENPVHINSWFDDSIQPLKEGLYAPKMEGVDQKTIDYVYHTAKKIYGENLPTIVEQRIKKELNSIIKHGFSVVYWISHLLVEKSMQDGYGVGSRGSVGSSLVATFLNITDVNPLTPHYLCPNCKKCEFITNADDGFDLAPKSCEQCQTPMLTDGHNIPFETFLGFDGDKVPDIDLNFSGVYQAVAHNFIKSIFGETHSYRAGTIGTMAQTSAENTVKKYFENRFNENKIIRDSTVSLYVQKCIDSKRTTGQHPGGIIIVPKEYSIWDFSPYNFPANDINETWKTTHFAFEYLHDSLLKFDILGHDNPTILKLLKDYTGIDERDVPMYDPLVMKSFSDISALNIKPSDVLNETTGAISIPEFGTRFVRGMLVDTKPKSFADLIRISGLSHGESVWLGNAQSLIKSGKLLKDVIACRDDIMTYLIRQNVEPKTAFLIMEDVRKGKKIKPEHQIILKELKVPEWYIESANKIKYMFPKAHATAYVMHAWKFAWYKIYYPLEYYAAFFSVRADNFDLFVINQGKEFIEKTYNDIEQRSKSRDPQKKVSSRELALQPIYEIVIELLARGFKISNISIEQSQATSYVIDKENNAIIPPFIAIQGLGETVANSIIEARNQKVFSTIEDLKNRTKISRTDLKNLRVLGVLDHLSETEQLTLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Ureaplasma parvum serovar 3 (strain ATCC 700970)

Length

1442 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

166.229 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus epidermidis (strain ATCC 12228)

Length

1442 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

163.421 kDa

Sequence

MVIILAMTNREKFKVLADQIKISNQLEQDILEQGELTRIDVSNKNRTWTFQISLPHFLSHEDYLLFTHAIEEEFKEIATVAIDFSIKDTNNQDEFALKYFGHCIDQTRLSPKVKGQLKQKKLIMSGNVLKVLVSNDIERNHFDKACNGSLVKAFRQCGFEIDKVVFETDSTNHDDDLASLEAHIQQEDEQSAREATEKLEKMKAEKAKQQDNNESTVEKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVELKVTDYTDSLVLKMFTRKNKDDLDHFKALSVGKWVRAQGRIEEDTFVRDLVMMMSDIEEIKKTPKQDKAEDKRVEFHLHTSMSQMDGIPNISAYVEQAAKWGHQALAVTDHNVVQAFPDAHNAAEKHGIKMIYGMEGMLVDDGVPIAYKPTDRNLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLTDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVNNHLEINKKLTNEDAYKRARPSHVTLIVQNQEGLKNLFKIVSASLVKYYYRTPRIPRSLLNEYREGILIGTACDEGELFTAVMQKDQSEVEKIAKFYDFIEVQPPALYQDLMDRELIRDNETLTQIYKRLIDAGKSANIPVIATGNAHYLYEHDAIARKILIASQPGNPLNRSTLPEAHFRTTDEMLDDFHFLGEEKAYEIVVTNTNELANKIEKVVPIKDKLFTPRMDGANEEIRELSYSNAKKLYGEDLPQIVIDRLEKELDSIIGNGFSVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICSHCKTSEFFDDGSVGSGFDLPDKKCPTCGNELIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGFVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQFPADDQSAAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKETMQIFSGPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIRQGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKTMEFVRKGRGLTDEMVEAMKENNVPDWYLDSCRKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYAAYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGFRLQPISLEKSQAFDFIIEGDTLIPPFISVPGLGENVAQRIVEAREEGPFLSKEDLNKKAGLSQKVIDYLDELGSLPDLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain Mu3 / ATCC 700698)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.693 kDa

Sequence

MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYTNARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain bovine RF122 / ET3-1)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.656 kDa

Sequence

MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFIHAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGAPIAYKPQDVVLKDATYVVFDVETTGLSNQYNKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNQDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain COL)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.663 kDa

Sequence

MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain Newman)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.663 kDa

Sequence

MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain Mu50 / ATCC 700699)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.693 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain N315)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.693 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain MRSA252)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.709 kDa

Sequence

MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKSKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEYKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGETLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain MSSA476)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.663 kDa

Sequence

MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus epidermidis (strain ATCC 35984 / RP62A)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.983 kDa

Sequence

MAMTNREKFKVLADQIKISNQLEQDILEQGELTRIDVSNKNRTWTFQISLPHFLSHEDYLLFTHAIEEEFKEIATVAIDFSIKDTNNQDEFALKYFGHCIDQTRLSPKVKGQLKQKKLIMSGNVLKVLVSNDIERNHFDKACNGSLVKAFRQCGFEIDKVVFETDSTNHDDDLASLEAHIQQEDEQSAREATEKLEKMKAEKAKQQDNNESTVEKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVELKVTDYTDSLVLKMFTRKNKDDLDHFKALSVGKWVRAQGRIEEDTFVRDLVMMMSDIEEIKKTPKQDKAEDKRVEFHLHTSMSQMDGIPNISAYVEQAAKWGHQALAVTDHNVVQAFPDAHNAAEKHGIKMIYGMEGMLVDDGVPIAYKPTDRNLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLTDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVNNHLEINKKLTNEDAYKRARPSHVTLIVQNQEGLKNLFKIVSASLVKYYYRTPRIPRSLLNEYREGILIGTACDEGELFTAVMQKDQSEVEKIAKFYDFIEVQPPALYQDLMDRELIRDNETLTQIYKRLIDAGKSANIPVIATGNAHYLYEHDAIARKILIASQPGNPLNRSTLPEAHFRTTDEMLDDFHFLGEEKAYEIVVTNTNELANKIEKVVPIKDKLFTPRMDGANEEIRELSYSNAKKLYGEDLPQIVIDRLEKELDSIIGNGFSVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICSHCKTSEFFDDGSVGSGFDLPDKKCPTCGNELIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGFVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQFPADDQSAAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKETMQIFSGPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIRQGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKTMEFVRKGRGLTDEMVEAMKENNVPDWYLDSCRKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYAAYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGFRLQPISLEKSQAFDFIIEGDTLIPPFISVPGLGENVAQRIVEAREEGPFLSKEDLNKKAGLSQKVIDYLDELGSLPDLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus haemolyticus (strain JCSC1435)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.95 kDa

Sequence

MAMTNQEKFKVLADQIKVSNQLDQTIIEKGELTRVDVSNKNRTWEFQITLPYFLSHEDYLIFTNAITEEFKEIAKVDWHFTIQDTSNQDEHAIKYFGHCIEHTALSPKVKGQLKQKRLIMSGNVLKVMTSNDIERNHFDKVCNGSLVKAFRKCGFDIDKVVFETDDSSSYDDLASLEAHIQEEDEKSAREATEKIEKIKAEKAKQQDNNESNVDKCQIGKPIQIDNIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVELKVTDYTDSLVLKMFTRKNKDDLDHFKALSVGKWVRAQGRIEEDTFVRDLVMMMTDIEEIKKTPKQDKAEEKRVEFHLHTSMSQMDGIPNISAYVNQAAKWGHKAIAVTDHNVVQAFPDAHGAAEKNGIKMIYGMEGMLVDDGVPIAYKPTDRDLKEATYVVFDVETTGLSNQYDQIIELAAVKVKDGEIIDKFERFSNPHEKLSETIINLTHITDDMLTDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTESTAYIFIKMVQQMKELGVTNHKDINQKLSNEDAYKRARPTHVTLIVQTQEGLKNLFKIVSASLVKYYYRTPRIPRSLLNEYREGILVGTACDEGELFTAVMQRDQSEVEKIAKYYDFIEVQPPKLYQDLIDRELIRDTETLYEIYERILKAGESTGIPVIATGNAHYLYEHDAIARKILIASQPGNPLNRSTLPEAHFRTTDEMLDEFHFLGEEKAHEIVVKNTNELADRIEKVIPIKDQLFTPRMDGANEEIRELSYTNAKKLYGEDLPQIVIDRLEKELASIIGNGFSVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFDDGSVGSGFDLPDKQCSTCGAELIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQSASWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKETMQIFSSPESLGVTEEEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIRSGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKTMESVRKGKGLTEEMIDAMKENNVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKESIKNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGFRMQPISLEKSQAFDFIIEGDTLIPPFISVPGLGENVAKRIVEAREDGPFLSKEDLNKKAGLSQKIIEYLDDLGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)

Length

1438 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.441 kDa

Sequence

MAMTNEEKFKILADQIKITEHLDSEILENSELTRVDVKTSDRTWVFQITFPHFLTIENYLLFTGAIIEEFKTIADVKCNFTVKDKTNQDEFAIKYFSHCIDQTKLSPKVKGQLKQKRLIMSGDVLKVMCQNDVERDHFDKACNGSLIAAYQQCGFNISKVVFETDSAVNDGDLASLEAHIQEEDEKSAREATEKLEKMKAEKAKQQDNNESDVSKCQIGKPIQVENVRQIDSIIEEEFKAAVEGVIFDINLKELKSGRHIVELKVTDYTDSLVLKMFTRKNKDDLAHFKALSVGKWVRAQGRIEEDTFVRDLVMMMSDIEEIKKATKQDKAEDKRVEFHLHTSMSQMDGIPNISDYVDQAAKWGHKAIAVTDHNVVQAFPDAHSAAEKNGIKMIYGMEGMLVDDGVPIAYKPKDCDLKTATYVVFDVETTGLSNQYDKIIELAAVKVKDGEIIDKFERFSNPHERLSETIKNLTHISDDMLVDAPEIEEVLTEFKSWVGDAIFVAHNASFDMGFIDTGYEHVGIGASTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYMFIKMLKQLEALGVHNHQDINTSLSNEDAYKRARPNHVTLIVQNQDGLKNLFKIVSASLVQYYYRTPRIPRSLLDEYREGILVGSACDEGEVFTAVMQKDQSQVERIAKYYDFIEVQPPALYQDLIDRELVRDNETLHEIYNRLIRAGDVNNIPVIATGNAHYLNEHDAIARKILIAAQPGNPLNRSTLPKAHFRTTDEMLDELHFLGEEKAYELVVQNTNDLADKIERVVPIKDELFTPRMEGANEEIREMSYDNAKALYGDDLPQIVIDRLEKELESIIGNGFSVIYLISQRLVKKSLNDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPECKQSEFFDDGSVGSGFDLPDKKCESCGCDLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPEAHNYTKELFGEDKVFRAGTIGTVAEKTAFGFVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPVQFPADDQGSSWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKETMGIFSSPEPLGVTSDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVRISGLSHGTDVWLGNAQDLIRSGKCDLASVICCRDDIMVYLMYNGLEPSLAFKTMEFVRKGKGLTDDMVEAMVDNEVPDWYLDSCRKIKYMFPKAHAAAYVLMAVRIAYFKVHYPLYYYASYFTVRASDFDLISMIKDKESIRNTVNDMYSRYMDLAKKEKDTLTVLEIMNEMAQRGYRMQPISLEKSKAFEFIIEGDTLIPPFIAVPGLGENVAQRIVEARDEGPFLSKEDLNKKAGLSQKVIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Bacillus subtilis (strain 168)

Length

1437 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.663 kDa

Sequence

MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKSWHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTSSIEVQDAEVSESIVQDYWSRCIEELQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPDLQLDAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITVQGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIKAKTREDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEANLVDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDMLQDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVAYKKLLEVEKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDIELTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANITKLGEKLNKPVVATGNVHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEEKAKEIVVTNTQKVASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKELKSIIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLVQGCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELSEVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMEDINAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRSSATEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)

Length

1437 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.045 kDa

Sequence

MSLNQQEMFEKLLEQIEMPTGPEFTEAAIDKLTVHQASKVWEFHLHFQHVLPYTQFMTFQNKLQIAFKEIARVTFTIVTDDTEVNGRELAEYWEWIVQHSGIKSPLVQSLCNSNVPTYEDGRVILLAENEVIQNFLTNQALGPIESTYHRLGFPKFSVHTMIDESASQAKIKEFHEQKAKSDQALAQKAEAAIKKANEKRQKQADAPAPIDGPVQLGKQINPQEPAKQMVQITEEERSVVVEGYVFDMEVRTLRSQRQLLILKVTDYSSSMVVKKFSRNADDEAQFAALKPGMWVRVRGSVQEDSFMRDLTINAYDINETSHASRQDTAPADEKRVELHLHSNMSQMDATNSVSDYVKQAAKWGHPAIAITDHSGAQAFPEAFAAGEKNNIKILYGVEANMVDDGVPIAYNDAHVDLKESTYVIFDTETTGLSAIYDRVIELSAVKMVKGNVVDQFEEFIDPGFHLSETTTNLTSITDDMVRGSKSEEEVFKLFREFYGDAIVVGHNVTFDIGFMNTGYARHHMGPITNPIIDTLTLARWLYPNLRGYRLNTLAKKFNVNLEHHHRAIYDAETTGHLNHLFLKDAEDRYQVQFHDQLNDHMNENAAYRHARPFHATLYAQTQAGLKNLFRIISLSNVEYYYRVPRVPRSVLNKYRDGILVGSACSSGEVFTAMMQKGKEEARQKAGYYDFLEVQPKPAYSALIESGLIADTDHLEEIISNMVELGHEMNIPVAATGDVHYLNPEDKIYRKILIHSQPGNPLNRTERPDVHFRSTDEMLKDFDFLGTETAHEVVVDTPRALADQFEIVRPVKDKLYTPRMKGAEAEIEKLTMDRAHAWYGNPLPEIVQKRVDKELKSIIGNGFSVIYLIAQRLVFKSNKDGYLVGSRGSVGSSIVATLSGITEVNPMPPHYRCPNCQYSHFYTNNEYGSGYDLPPKDCPECGTDMVRDGQNIPFETFLGFYGNKVPDIDLNFSGDYQPIAHNYTKVLFGEKNVYRAGTIGTVADKTGYGYVKAYERDTNQTLRSAEVDRLAKGTTGVKRTTGQHPAGIIVVPDYMDIYDFTPVQYPADDQSAAWQTTHFDFHSIHDNILKIDILGHDDPTMIRMLQDLSGVQPESIPPVDPHVMKIFSSPEVLGVTEDQIFSKTGTLGIPEFGTRFVRGMLEETHPSTFNELLQISGLSHGTDVWLGNAEELIKDGTVTLAEVIGCRDNIMTDLIHYGMESDMSFQIMEHVRKGRGIPDEWQQAMKDANVPDWYIESCLKIKYMFPRAHAAAYILMALRVAYFKVYFPLIYYTAYFSVRADDFDLVAMAHGKDAVKASMKAITDKGMDASAKEKNLLTVLELANEMLERGFKFSMVDLDKSDASDWLIDGDTLIAPFRAVPGLGLNVAKQIVAARADKPFLSKEDLSKRGKVSKSLIDFMTENGVLSDLPDENQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)

Length

1437 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

161.831 kDa

Sequence

MSLSENEQFRVLLEQIDLLDNAELKDGSIKDLTVHSNSKRWTFSFEFNDILPLQIFVEFHHQLVNTFGSIAQIDFSIDTINKNNVATHATDYWDWIIKNSGIQSSLLQVLCDKSIPEFKDGQLVVKVDNQITKNFLNDDVLQTLSNTYQKVGFGPIKIKPTIDDNTAQERLQAYHEEKIKRDQAIVQKATEAIKKAESKKKASDKAMPEFNGKVQMGKPINGKDNIVQLRDITQEERSVSIEGYIFDAEVKTLRSERQLLIFKVTDYTSSITIKKFSRNEADEQLFSAIKKGLWVRVRGSIQEDSFMKDLTMNAYDIMEVDHADRQDTATDKRVELHLHTNMSTMDATNGISDLVGQAAKWGHPAVAVTDHAGLQAFPEAHAAGKKSGIKTLFGVEANLVDDGVPIGYNSEHCPLKGGKYVIFDVETTGLSAIYDKVIELSAVKMENGNVIDQFEEFIDPGFPLSETTINLTSITDEMVRGSMSEKEVFTKFREFYEDAIIVGHNVTFDIGFMNTGYLRHGMEEIKNPIIDTLTLARFLYPTLKGYRLNTLAKKFGVALEHHHRAIYDSETTGHLCYLFLKDAEERYGIEYHDQLNDHMTENEAYKHARPSHAILIAKTQAGLKNLFKLVSMSNVKYYYRVPRIPRSELEKLREGIIVGSACSSGDVFTAMMQKGYADARRKAKFYDYLEVMPKPVYQPLIEQELVSDNKKLEEIIANIVKLGEDLDIPVVATGDVHYLNPQDYIYRKILINSQGGANPLNRSELPDVHFRTTDEMLEDFSFLGPEVAHKIVVENSNKIADSVDDGISPVKDKLYTPKMPGAEDRIKQLSMDRAHALYGEVLPEIVQERLDKELTSIIGNGFSVIYLIAQRLVHKSNKDGYLVGSRGSVGSSFVATMSGITEVNPLPPHYRCPKCQYSFFYTKGEYGSGYDLPDKECPECGTWMIGDGQDIPFETFLGFKGDKVPDIDLNFSGDYQPIAHNYMQVLFGKDNVFRAGTIGTVADKTAFGYVKAYERDTNQHLRGAEIERLAKGATGVKRTTGQHPAGILIVPDYMDVYDFSPIQYPADDQTAAWETTHFDFHSIHDNILKMDILGHDDPTMIRKLQDLSGIDPETIPTDDPGVMKIFSGPEVLGVDENQIQSKTGTLGIPEFGTRFVRGMLEETHPTSYSELLQISGLSHGTDVWLGNAEELIKAGTVTLKEVIGCRDNIMMDLIHYGLDSQSSFQIMESVRKGKGIPEGYEDKMRAANVPDWYIESCGKIKYMFPRAHASAYVLMALRIAYFKVYYPLVYYAAYFTVRADDFDIVSMARGKESLKNRMQEINDKGNDASTKEKNLLTVLELANEMLERGFEFKMIDIEKSDAEEWLIEGKSLIAPFNALPGLGLNVAKQIVAARADKPFLSKEDLSKRGHVSQTLIDFMTENNVLSELPDENQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain USA300)

Length

1436 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.46 kDa

Sequence

MTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain NCTC 8325)

Length

1436 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.46 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus (strain MW2)

Length

1436 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.46 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)

Length

1435 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

161.926 kDa

Sequence

MLMSLTNEQQERFQILLQQLQIPDDLINQYLQGGGIERLVIDKANKSWHFDLQVPRILPTELYELLETKLKQSFSHIARTTFALETENKQFTEEEVRAYWPLCTERITFSPMFAYLKKQLPQVNGVKLLINVNNELESTALKKNVAKPVGDQYEVFGFPRFQLDTHIQQNTEEMQKFREQTQQEDRERVIQAMEEMAKKQAEESSVVYEGPITLGYLIKPDEEITPMREIQDEERRKTVQGYVFHVETKELRSGRTLLTLKITDYTDSIMIKMFSRDKEDIPMLQSLKKGMWVKARGSVQNDTFVRDLVMIANDINEITGPSRKDKAPEGEKRVELHLHTPMSQMDAVTPVSKLVAQAGKWGHEAIAVTDHAVAQSFPEAYSAGKKAGVKVIYGVEANLVNDGVPIAYNEAHRLLAEETYVVFDVETTGLSAVYDTVIELAAVKVKGGEIIDRFESFANPHQPLSATIIELTGITDDMLTDAPEVDEVFKKFEEWMGDHTLVAHNASFDMGFINVGFKKAGLEKTNNPVIDTLELARFLFPEMKNHRLNTMCKKLDIELTQHHRAIYDTEATGYLLVKMLKDVIEKGFEYHDQLNDSMGQGDAYKRGRPSHMTLLATSDVGLKNLYKLVSYSHLNYFYRVPRVPRSLLKKYREGILVGTACDKGEVFEAMMQKAPEEVEEIAQFYDYIEVMPPEVLRHLVERELVRDEGQLKTIISNLVKLGETLDKPVVATGNVHYLDPEDAMYRKILVSSQGGANPLNRHSLPPVHFRTTDEMLECFSFLGEDKAKEVVVTNTQKIASLIGDVHPVKDDLYTPKIEGADDETRDMSYKMARSIYGEELPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVGSRGSVGSSFVATMMEITEVNPLPPHYVCPKCKQSEFFNDGSVGSGFDLPDKECPACNIPYVKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKVLFGEDYVYRAGTIGTVAEKTAYGYVKGYANDHNLTIRNAEIDRLVAGCTGVKRTTGQHPGGIIVVPDYMDIFDFSPIQYPADSIGAEWRTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFSGPESLGVTEEQINCKTGTLGIPEFGTKFVRQMLEETKPTTFSELVQISGLSHGTDVWLGNANELIYNGTCTLSEVIGCRDDIMVYLIYQGLDPSLAFKIMESVRKGKGVPEEWEEDMKNNNVPGWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKVHFALLFYAAYFTVRADDFDVEAMAKGSASIRARIDEIAQKGLDAAPKEKSLLTVLEMTLEMCERGYSFQKVDLYRSHATEFIIDGDTLIPPFNAVPGLGTNAALSIVEARKNGDFLSKEDLQQRSKVSKTIIEYLDSQGCLGDLPDQNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Mycoplasma pulmonis (strain UAB CTIP)

Length

1435 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

166.375 kDa

Sequence

MQESFLNFCQEINFDIPEYLKNTKIANPYHDEEKSFFSCEIDFLETPKFEDFKSFYLKTKNFLNQLVKEQKLLFKIENIFYEKSEIKKYLDWIAEHFFKNFDFKNTFRIDDLKVNLDGKIFLTAHSKHSFDLYKDFVEFANKKMQSFGFENFLLKLELNQIEITNNQPLVSSINSQVKTQASSENQSFKKSNFYNKKRHIQLSLKELIKTQEMFVSVVGMVFKKEIITTNSKTKIFKISITDFQEATRAQKFSYLEKDQEIFDSIQINDWVNVCGEIQLEKMSLKQFIKIEKIEKIRSPIKDRQDNEKEKRIELSFRSKMSTMDGILSPLDIVKQAKKFNHSSIAILDHNSVQAFPDFHNLTYKDKDFKVIYGMTLSVISKRNKIFVEPLKDKFFDYKILDQEYVVYDIETTGLSPMLNELIQFGASVIKNGRIIETHHFFIKPKSKLDSFTTKLTGITQEHLEKGYELQEALEKISSIFKARIMVAHNAAFDHNFLKQKFIDNNIEFEEMISIDTLNLAKVLNPIYRSYRLGEVASKLSVVYDPSIAHRADYDSSVLTNIFILQMSHLKEKGINLFKELNSLSSEKFYSKMFAKDISIIAKNQAGLKELFKINSDVLTKYYFANPKMFWEDIKRSKNLLIGSGGLNSPLIDKLLFSTQEDVLNEIDKYDYIEIPSPNNFSHFWTTKFSDQQIKIQLQKLIKWAKEKNKIIVAIGEPRYNEKWQKIIHEIYINSTGIENSLHPLFIIKKDMDTFYPEQIYKTTNEMKQEFSFLYDPELIEEIVVKNPNLISSQIEKIQVIKDKLYTPKFDDSHIKLKKLVYENAWKKYGKNLPEIIEQRIEKELTPILNYGFDVIYWISSILVQKSLSDGYLVGSRGSIGSSLVATLSGITEVNPLAPHYICSKCQYFELVKDPMTNSGFDLDDKKCPKCNSFLDKDGQTIPFETFLGFKADKVPDIDLNFSGEYQGKIHDEVKRLFGSKHTFRAGTISTVAEKTAYGYIKKYLETASLDYSDNFVDFLTEKSTGVKRTTGQHPGGIIIIPKEFDVEDFTPVNFPANDTESSWKTTHFDFHAIHDNVLKLDILGHDDPTALKMLEKLTGVNVKDIPKKDEKIISIFTSPKALGISSEEILGEKTGALGIPEFGTNFVRQMLSEAKPKTFADLVSISGLSHGTDVWINNAHYIIQSLGKTLDQVISCRDDIMVDLIKKGVPIDLSFTIMEQVRKGKGLSLEQKRKLIEHGIENWYIESMEKIKYMFPKAHATAYVLMAWRVAFYKVYYPLEYYATYFSTRTEFFDIEIMSKDKLTLESKIKELAYRENLRNDNQLTTKEKNTLPTLYIANEMKARGFNIQNINLKISLANDWIIDKNSKSLIPPFNVIDGLGETLAQKIVDSRNEKEFLSVEDFINRTGINSTLVEKFKSMGIFEQIPETNQIFLI

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Staphylococcus aureus

Length

1435 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.477 kDa

Sequence

MTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNKQSAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFEKFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKATTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPNSDRIRRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYIFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLYQKIIEYLDELGSLPNLPDKAQLSIFDM

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

Length

1433 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.126 kDa

Sequence

MNEEQRVRQERFKLLMEQLLIPEDVTANHLKDGKIEKLTIKKDERRWHFQLSIPTVLPASIYELLADRLVQTFSHIAKVSFQIQYGQPDLSEQVWQSYWPLIVAKLTNISQPLKEMLEKQTPRFDGKRLVIQVGNETEAIALKRKLTEPLQQAVQSFGFPAVQLDAEVKESKQAFEKFVEQRKQEDHSKVVEAILEKKKLEQQVEKKMKEEKLTIGYPIKDEPVPLETIVEEERRITVQGYIFAAETKELRSGRTLLTFKITDYTDSILVKMFSRDKEDIPLLQAVKKGMWVKVRGGVQNDTFVRDLVMIANDVNEVSGKETKDEAPDDEKRVELHLHTAMSQMDGISSAGAYVTQASKWGHKAIAITDHGVVQAFPEAYGASQKHGIKVIYGVEANLVDDGVPIAYNEAHIPLLDSEFVVFDVETTGLSAVYNKIIELAAVKVKNGEIIDRFERFADPHEPLTNTIIELTGITDDMLKGQPEVEQVLNEFHAFIGDAVLVAHNASFDMGFLNTGFQKMGLGEAKNPVIDTLELGRFLYPTLKNHRLNTLCKKFDIELVSHHRAIYDAEATGHLLWRMVKDATERDILYHDQLNDNMGEGNFHRQRPSHCILLAQTQEGLKNLYKLVSMAHVEYFYRTPRIPRSQLQKHREGILVGSGCDKGEVFEGMMQKTPQEVEEIAKFYDYIEVQPLANYEHLIEKELVKSREALQEIVANIVKLGEQLGKPVVATGNAHYLKEEDYIYRKILIASQGGANPLNKQTLPQVHFRTTSEMLEAFAFLGEEKAKEIVVTNTNHIADQIEEIHPIPDKLYTPKIEGADEEIRQMSYNRARKIYGDPLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYVCPNCHHSHFFNDGSVGSGYDLPDENCPKCGTPYVKDGQDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKELFGESYVYRAGTIGTVAEKTAYGYVKGYQSDHDLHFRGAEIDRLVTGCTGVKRTTGQHPGGIIVVPDYMDIHDFCPIQFPADDRGAEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFSGPDVLGVTEEQILCKTGTLGIPEFGTRFVRQMLEETKPSTFSELVQISGLSHGTDVWLNNANELIYNGTCELKDVIGCRDDIMVYLIYKGLEPSLAFKIMEFVRKGKGLQPEWIEEMKKHDVPDWYIGSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHYPILYYASYFTVRADDFDLDTMVKGSAAIRAKIEEINGKGLDASPKEKSLLTVLELALEMVERGFSFQKVDLYRSEATEFLVEGNTLIPPFNALTGVGTNAAINIVKARDEREFLSKEDLQQRSKITKTVLENLDAHGCLEGLPESNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

Length

1431 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

162.928 kDa

Sequence

MELPKEMEEYFSMLQREIDKAYEIAKKARAQGKDPSLDVEIPQASDMAGRVESLVGPPGVAERIRELVKEYGKEIAALKIVDEIIDGKFGDLGSKEKYAEQAVRTALAILTEGVVSAPIEGIASVKIKRNTWSDNSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRTVSRLQYHPSPEEVRLAMRNIPIEITGEATDEVEVSHRDIPGVETNQLRGGAILVLAEGVLQKAKKLVKYIDKMGIEGWEWLKEFVEAKEKGEEIEEEGSAESTVEETKVEVDMGFYYSLYQKFKSEIAPNDKYAKEIIGGRPLFSDPSRNGGFRLRYGRSRVSGFATWGINPATMILVDEFLAIGTQLKTERPGKGAVVTPVTTIEGPIVKLKDGSVVKVDDYKLALKIRDEVEEILYLGDAVIAFGDFVENNQTLLPANYCEEWWILEFTKALNEIYEVELKPFEVNSSEDLEEAADYLEVDIEFLKELLKDPLRTKPPVELAIHFSEILGIPLHPYYTLYWNSVKPEQVEKLWRVLKEHAHIDWDNFRGIKFARRIVIPLEKLRDSKRALELLGLPHKVEGKNVIVDYPWAAALLTPLGNLEWEFRAKPLHTTIDIINENNEIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGSSRDIKKAAEEGKVAEVEIALFKCPKCGHVGPEHICPNCGTRKELIWVCPRCNAEYPESQASGYNYTCPKCNVKLKPYAKRKIKPSELLKRAMDNVKVYGIDKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHFRPREIGVSVEKLRELGYTHDFEGNPLVSEDQIVELKPQDIILSKEAGKYLLKVAKFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRIIGFVDALVGYAHPYFHAAKRRNCFPGDTRILVQINGTPQRVTLKELYELFDEEHYESMVYVRKKPKVDIKVYSFNPEEGKVVLTDIEEVIKAPATDHLIRFELELGSSFETTVDHPVLVYENGKFVEKRAFEVREGNIIIIIDESTLEPLKVAVKKIEFIEPPEDFVFSLNAKKYHTVIINENIVTHQCDGDEDAVMLLLDALLNFSRYYLPEKRGGKMDAPLVITTRLDPREVDSEVHNMDIVRYYPLEFYEATYELKSPKELVGVIERVEDRLGKPEMYYGLKFTHDTDDIALGPKMSLYKQLGDMEEKVKRQLDVARRIRAVDEHKVAETILNSHLIPDLRGNLRSFTRQEFRCVKCNTKFRRPPLDGKCPICGGKIVLTVSKGAIEKYLGTAKMLVTEYKVKNYTRQRICLTERDIDSLFETVFPETQLTLLVNPNDICQRIIMERTGGSKKSGLLENFANGYNKGKKEEMPKKQRKKEQEKSKKRKVISLDDFFSRK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)

Length

1428 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

161.813 kDa

Sequence

MDISKKEKLKLLLEQIRMPDNEIEAHFSNSYLDKVEVHKADKKWHFYINIDHVLPFQTYQLFHHSLKESFASIAEVSLTLSAENRHCPEGDIQIYWKHFIAQTSLSPAYRDLVLDQAPEVSNNKIMLTARNEAEASALKKRLEAKFHDFCLSIGSLPYTLEVEVKTNTEAMQEFRDKKALEDQQLVMKTVQEKEKRDKDKSVPDQQPLAIGYKIQDEPITMDQIIDEERRITVQGYVFDAEVRELRSGRSLLIIKATDYTDSIQIKMFSKGDEDAAKFASVKKGMWVKARGSIQTDMYTNELAMMAKDIHEIHVSQRMDDASEDKKRVELHTHTTMSQMDAVVSPEALVEQAAKWGHKAIAITDHAGVQGFPDAHNAGKKHGVKVLYGVEANLVDDGVPIAYNEADRNLYEDTFVVFDVETTGLSAVYDTIIELAAVKIKGGEIVDRFESFANPHHALSQTTIDLTGITDDMVNDAPEVADVLKDFHTWMGNDILVAHNASFDMGFLNQGFQRIDYEKASNPVVDTLELARFLLPELRNHRLNTLCKHLDIELTQHHRAIYDAEATGYLLWKLVQRLVEKEISNHLELNNHMGENNAYQRSRPYHCTLIAQTEEGLKNLYKLVSRAHIDFFYRVPRLPRSVLQKHREGILVGTACDKGEVFETMMQKSEEEAEQVADFYDYIEVQPPENYTHLIEKDLVQNESQILDILRKLVNLGDKMKKTVVATGNVHYLHEHDKQYRQILIGSQAGNPLSRHKLPDTPFRTTTEMINCFHFLGEKKANEIVVDNTQKLTDSIEEISPVKDGLFTPNIEGAEQEMRDLCYNKAKEVYGEPVPQIVVDRLEKELESIIGNGFAVIYLISQKLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLVPHYVCKHCHHHEFFTDGSVASGFDLPDKDCPGCGKGLTKDGQDIPFETFLGFKGDKVPDIDLNFSGDYQPRAHNYTKELFGIDNVYRAGTIGTVAEKTAYGYVKGYASDNQFVYKNAEVDRLVQGCTGVKRTTGQHPGGIIVVPSDKEIYDFTPIQFPADDRNSEWRTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGMDPKNIPTDDEEVMKIFSGTESLGVTPEQINCKTGTLGVPEFGTKFVRQMLEDTKPKTFAELLIISGLSHGTDVWLGNAQELINDGICQLPDVIGCRDDIMVYLMHKGLDPSMAFTIMEFVRKGKGLKDEWIDEMKKHAVPDWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPILFYAAYFTVRADDFELDTMIKGSDAIRKRIEEITVKGNDASPKEKNLLTVLEISLEMCERGFSFKKVDLYQSSATDFIVEGDSLLPPFNAVDGLGTNAALNIVKAREEGEFLSKEDLRERSKISKTVLEYLDNHGCLEGMEDKNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Clostridium tetani (strain Massachusetts / E88)

Length

1427 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

162.36 kDa

Sequence

MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKFQYFKEIEVLSYRDVSGINLKDICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKLQYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDKSNGKCNYLDFKEEQEALIIKNIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVFKTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSYAREIVIMARDIVKLNKIEKMDIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAVAITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPIAINAGHRTLEDSYVVFDIETTGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEEVLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKLNVVAKHLGIPLLNHHRAVEDAKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSPTYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLINKYREGLMIGSACEAGQVYKEVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNMPVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKAVVTNTVKIADSIDNIKPIPDETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEKELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSSLVATMTDITEVNGLPPHYVCPGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLGCSGVKRTTGQHPGGIMVVPQDNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKALGVNAEELKCEVGTYGLPEFGTKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTYLIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAYVMMAVRIAYFKVYYPTAYYATYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKDKGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGIRIPLSAIQGVGENAAKNIVEAREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)

Length

1401 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

158.806 kDa

Sequence

MVPATFLENMQIKKVRVEKKSRKLTVVVSSFSSNAQKLSEFQSFLEESFPSLKEIKIVVESPSLSTVEEVLENWEKVVLELSEEYPSSLSFLKTCDVAKEGQNRITVKAPTYAIYEMAKSSKLDFAIREFLRNRYELNLDVELIFSEEGEEIAEKIIEEDIKAIEEVIQKDEKSKKEKSRSEENRVLLGKEMKAKPISIKDVSAETDEVVIEGEIFSIDFKELKSKVLMVFDITDYTSSILVKTFLTEEKYEILKDEIDVGTFVRLRGNVIYDKYEGDLVIDLKDLELIPPKKRMDLSEEKRVELHLHTQMSTLDAVPSATEVIKRAAEWGHKAVAITDHAVVQAFPEAMEASREYGVKVIYGMEGYMVDDGIPIVTGESEASLEGEFVVFDIETTGLSNINDEIIEIGAVKIKNKKIVDTFETFVNPQIPISSFITKLTGIDESMVKDAPLIEEVLPKFLEFAKGAVLVAHNANFDVSFIKSKAKKLGLTVENTVLDTLELSRHLYQDLKNYKLDTLAEFFEVKLLHHHRAVEDAKATAEIFIKMLEKLQEIGIKSVSEINSVLMEREVDVKKLPVYHVTILVKDQKGLRNLYEIISRSNLEFFHRTPRIPKSLLVKMREGLIIGSACEQGEVFRALVSNLEEKKLEDIINFYDYLEIQPVGNNEFLIERGEVRSVEELKEINRKIYELGKKYNKLVVATGDVHFLDPWDDVYRKILMAGKGYKDADRQPPLYFRTTEEMLMEFEYLGEEAAREVVIENPNKIAEIVEDVKPIPEGTFPPVIEGAEEELRRITLEKAHEIYGDPLPPIVQERLDRELNAIINNGYAVMYVIAQKLVSKSLQDGYLVGSRGSVGSSLVATMSGITEVNPLPPHYVCPKCKHSEFVTDGSFGCGVDMPDKYCPNCGTLMKKDGFDIPFEVFMGFEGDKEPDIDLNFSGEYQPIAHRYTEELFGKGHVFRAGTIGTLADKTAYGYVKKYFEERNLTVHKSEIKRLTMGCTGIKRTTGQHPGGVMVVPKDKSIYDFTPIQRPADAEDTDVITTHFDYHSLSGKLLKLDILGHDDPTVIRMLEDLTGVNARKIPLDDKKTMSLFTSVEALGIDPEELGTPVGTLGLPEFGTKFVRQMLIETRPTTFDELVRISGLSHGTDVWLNNAQDIIREGIATLKEVIAARDDIMLYLISKGMDKKLSFKIMENVRKGKGVTQEEIEEMKKHGVPDWFIQSCQKIKYMFPKAHAVAYVIMAFRIAYFKVYYPEAFYATYFTVRADDFNLDIVLGGKESIKRAIKEIEAKGNNATPKEKNLLTVLEVALEMYLRGIKFTNVDLYRSDAEKFLITEEGLLPPLNSLEGVGIQAAKAIAQERENGKFISIEDFRNRTRVSKTVIEILKQYGCLEDLPESNQLSLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Length

1395 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

153.633 kDa

Sequence

MREADEQYFETLETQLEAAFDVAERAKERGGDPKPEVEIPTARDMADRVENILGIDGVAERVRELEGQMSREEAALELVEDFVEGTVGDYDSREGKVEGAVRTAVALLTEGVVAAPIEGIDRVELLENDDGTEFINVYYAGPIRSAGGTAQALSVLVADYARALLGIDQYKAREEEIGRYAEEIDLYDKDTGLQYSPKEKETKFIAEHMPIMLDGEATGDEEVSGYRDLERVDSNSPRGGMCLVLAEGIALKAPKIQRYTRNLDEVDWPWLQDLIDGTIGKDEADEGDSAEDANGDDAGEGADDDGGDEADEQAGPPRVEPADKYLRDLIAGRPVFSHPSKSGGFRLRYGRSRNHGFATAGVHPATMHLVDDFLATGTQIKTERPGKAAGVVPVDTIEGPTVRLANGDVRRIDDAEEALAVRNGVEKILDLGEYLVNYGEFVENNHPLAPASYTVEWWEQDLAAAGADVQAMQDSPHIDLADPSAEEAIEWATEYDAPLHPKYTYLWHDVSIEQVCALADAVEDAQVAQADGAYADPEMDGTAGDAHSDDGALVLPRSDAVQQTLEHLLIGHTQDEETITVTDWVPLVRTLGFSRSLERDWTREDLSEHARTYGESESLDAIGVAEDAEREDGQNAIKAINEVAPFQVRERAPTRIGNRMGRPEKSERRDLSPAVHTLSPIGEAGGAQRDVAKATKHADDMSDTPGQVEVEVARRRCPDCGTETHQANCAECSGTTEPVYVCPDCEAEVERDESGRAECGRCETLASPTQYKVLDLQEAYRDALQNVGERETAFEQLKAVKGLTSEEKVPEPMEKGILRAKHDVSAFKDGTVRYDMTDLPVTAVRASELDVSAERLRGLGYTEDIHGDPLTHEDQLVELKVQDIVLSDGAAEHMLQTARFVDDLLEQYYGLERFYEFDDREDLVGELVFGMAPHTSAATVGRVVGFTSAAVGYAHPYFHAAKRRNCFHPDTRLWYEDENDDWEYGTIEELVESRLDDPQEDDFGTLVQELDGDLTVSSLGENGPCRQPVDAVSKHPAPDHLVEVAVGDRTLRVTPDHTMLRAGPDGIEEVPASDLAAGDDLPAYDGGETTTMTARGEASTAATDGAAPTDTVEAVEYVESDVDHVYCLTVADTHRVAVEGTYVGQCDGDEDCVMLLMDGLLNFSKSYLPNQRGGQMDAPLVMSSRIDPSEIDDEAHNMDIMDAYPREFYEATREMKDPTEVEDVMKIAEETLGTDREYTEFRHTHDTANIAAGPDLSAYKTLGSMEDKMDAQLEISRKLRAVVESDVAERIIEYHFLPDLIGNLRAFSRQEVRCLDCGESFRRAPLTGDCRECGGRVNLTVHEGSVNKYIDTAIRVADEFGARDYTKQRLKILERKIESVFENDHNKQSGIADFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)

Length

1370 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

150.296 kDa

Sequence

MRPTDETYFETLETGLDDAFEVAEAARERGEDPTPNVEIPVAKDMADRVENILGIDGVAERVRDLDGEMSREEAALELVADFVDGRVGDYDTDAGKIEGAVRTAVALLTEGVVAAPIEGIDRVEVNDNDDGTQYVAVYYAGPIRSAGGTAQALSVLVADYARAMLGIDAFKPRDDEIERYAEEVDLYDSETGLQYSPKDAETTFITEHCPVMLDGEATGNEEVDGFRDLERIDTNSPRGGMCLVLAEGIALKAPKIQRYTRNLDEVAWPWLQDLIDGTIGADDADEDTPDAGSDSDATDEGDAPSASTDAEEPPRAAPSDKFLRDLIAGRPVFGHPSKNGGFRLRYGRARNHGNATAGVHPATMHLLDDFLATGTQIKTERPGKAAGIVPVDSIEGPTVKLANGDVRHINDPADALDVRNGVAEILDVGEYLVNYGEFVENNHELAPASYAPEWWIQDLDAAGADVQALRDSPYVDLTAPTADQAMAWATDYDAPLHPAYTYLWHDIDVEQFRALADAVADAHTDASDDDDRGVLVLDHTTTVRETLEALLVTHHQGDDTIRVDDWLPLARSLGVTESLDREWETLSEAAAEWPNAVRAVNEVAPFSVQERAPTRIGNRMGRPEKSESRDLSPAVHTLFPIGDAGGSQRDVADAARYAPDMSDTPGEIPVRVGDRVCPSCDEHTYESRCPDCGDWTDPHYECRDCGAVATPDESGRVECPNCGRDLDNVTTQVIDINDEYHGALRAVGERENAFDQLKGVKGLLSAEKTPEPMAKGVLRAKHDVTAFKDGTVRYDMTDLPVTAVTPAELDVTAGQFRELGYNQDIHGDPLEHDDQLVELRVQDVVLSDGAADHMLKTADFVDDLLTQYYGLDAFYDLDDRDDLVGELVFGMAPHTSAAVVGRVAGFTSASVGYAHPYFHAAKRRNCFHPETNVWFRDESGEWHHDPIETLVEARLDPDTADEDDFGALVQALDGDVFVPSVTEDGEETLQRVEAVSKHPAPDHLLAVETKRGRELTVTPDHSMRRWTGDGIERVDARELTAGDALPAPTQVPGDGETATSELRSESLDGTHPQRRFGDGGSVRTDEVVSVEPVRSSVDHTYSLTVAETNTLVANGLFTGQCDGDEDCVMLLMDGLINFSKSYLPDKRGGRMDAPLVMSSRIDPAEIDDEAHNIDIDREYPREFYEATRELADPEDVADLITLAESTVGTDEEYTGFGHTHATSNIHLGPSLSAYKTLGSMMDKMDAQLELARKLRSVAETDVAERVIEYHFLPDLIGNLRAFSRQETRCLDCGEKYRRMPLSGDCRECGGRVNLTVHEGSVNKYMDTAMRVATEYDCREYTKQRLEIMDRRLESVFEDDTNKQSGISDFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Length

1367 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

155.363 kDa

Sequence

MKKIENLKWKNVSFKSLEIDPDAGVVLVSVEKFSEEIEDLVRLLEKKTRFRVIVNGVQKSNGDLRGKILSLLNGNVPYIKDVVFEGNRLILKVLGDFARDRIASKLRSTKKQLDELLPPGTEIMLEVVEPPEDLLKKEVPQPEKREEPKGEELKIEDENHIFGQKPRKIVFTPSKIFEYNKKTSVKGKIFKIEKIEGKRTVLLIYLTDGEDSLICKVFNDVEKVEGKVSVGDVIVATGDLLLENGEPTLYVKGITKLPEAKRMDKSPVKRVELHAHTKFSDQDAITDVNEYVKRAKEWGFPAIALTDHGNVQAIPYFYDAAKEAGIKPIFGIEAYLVSDVEPVIRNLSDDSTFGDATFVVLDFETTGLDPQVDEIIEIGAVKIQGGQIVDEYHTLIKPSREISRKSSEITGITQEMLENKRSIEEVLPEFLGFLEDSIIVAHNANFDYRFLRLWIKKVMGLDWERPYIDTLALAKSLLKLRSYSLDSVVEKLGLGPFRHHRALDDARVTAQVFLRFVEMMKKIGITKLSEMEKLKDTIDYTALKPFHCTILVQNKKGLKNLYKLVSDSYIKYFYGVPRILKSELIENREGLLVGSACISGELGRAALEGASDSELEEIAKFYDYIEVMPLDVIAEDEEDLDRERLKEVYRKLYRIAKKLNKFVVMTGDVHFLDPEDARGRAALLAPQGNRNFENQPALYLRTTEEMLEKAIEIFEDEEIAREVVIENPNRIADMIEEVQPLEKKLHPPIIENADEIVRNLTMKRAYEIYGDPLPEIVQKRVEKELNAIINHGYAVLYLIAQELVQKSMSDGYVVGSRGSVGSSLVANLLGITEVNPLPPHYRCPECKYFEVVEDDRYGAGYDLPNKNCPRCGAPLRKDGHGIPFETFMGFEGDKVPDIDLNFSGEYQERAHRFVEELFGKDHVYRAGTINTIAERSAVGYVRSYEEKTGKKLRKAEMERLVSMITGVKRTTGQHPGGLMIIPKDKEVYDFTPIQYPANDRNAGVFTTHFAYETIHDDLVKIDALGHDDPTFIKMLKDLTGIDPMTIPMDDPDTLAIFSSVKPLGVDPVELESDVGTYGIPEFGTEFVRGMLVETRPKSFAELVRISGLSHGTDVWLNNARDWINLGYAKLSEVISCRDDIMNFLIHKGMEPSLAFKIMENVRKGKGITEEMESEMRRLKVPEWFIESCKRIKYLFPKAHAVAYVSMAFRIAYFKVHYPLQFYAAYFTIKGDQFDPVLVLRGKEAIKRRLRELKAMPAKDAQKKNEVSVLEVALEMILRGFSFLPPDIFKSDAKKFLIEGNSLRIPFNKLPGLGDSVAESIIRAREEKPFTSVEDLMKRTKVNKNHIELMKSLGVLGDLPETEQFTLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995)

Length

1367 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

155.335 kDa

Sequence

MEKIENLKWKDVTFESIEIDPDAGVVLVSVEKFSSEVENLVSLLEKETRFRVIVNGAQKSNGDLKGKILSLLNGNVPYIKDVVFEGNRLILKVLGDFARDRIASKLRSTKKQLDELLPPGTEIMFEVVEPPEDLLKKEVPQPEKREEPKGEELKIEDENHIFGQKPRKIVFTPSKIFEYNKKTSVKGKVFKIEKIEGKKTVLLIYLTDGEDSLICKVFNDVEKVEGKISLGDVIVATGDLLLENGEPTLYVKGITKLPEAKRMDNSPVKRVELHAHTKFSDQDAITDVNEYVKRAKEWGFPAVALTDHGNVQAIPYFYDAAKEAGIKPIFGIEAYLVSDVEPVIRNLSYDSSFENATFVVLDFETTGLDPQVDEIIEIGAVKIQDGQIVDEYHTLIKPSREISRRSSEITGITQEMLENKRSIEEVLPEFLGFLENSIIVAHNANFDYRFLRLWIKKVMGLDWERPYIDTLALAKSLLKMRSYSLDSVVEKLGLGPFRHHRALDDARVTAQVFLRFVEMMKKIGITKLSEIENLKDTIDYTALKPFHCTILVQNKKGLKNLYKLVSDSYIKYFYGVPRILKSALIENREGLLVGSACISGELGRAALEGASDSELEEIAKFYDYIEVMPLDVIAEDEEDLDRERLKEVYRRLYRIAKKLNKFVVMTGDVHFLDPEDARGRAALLAPQGNRNFENQPALYLRTTEEMLEKAMEIFEDEEIAREVVIENPNRIADMIEEVQPLEKKLHPPIIENADEIVRSLTMKRAYEIYGDPLPEIVQKRVERELNAIINHGYAVLYLIAQELVQKSMSDGYVVGSRGSVGSSLVANLLGITEVNPLPPHYRCPECKYFKVVEDDRYGAGYDLPDKKCPVCGAPLRKDGHDIPFETFMGFEGDKVPDIDLNFSGEYQERAHRFVEELFGKDHVYRAGTINTIAEKSAVGYVRSYEEKTGKKLRKAEMERLVSMITGVKRTTGQHPGGLMIIPKDKEVYDFTPIQYPANDRNAGVFTTHFAYETIHDDLVKIDALGHDDPTFIKMLKDLTGIDPMTIPMDDPDTLAIFSSVKPLGVDPVELESDVGTYGIPEFGTEFVRGMLVETRPKSFAELVRISGLSHGTDVWLNNARDWINLGYAKLSDVISCRDDIMNFLIHKGMEPSLAFKIMENVRKGKGITEEMESEMRKLKVPEWFIESCKRIKYLFPKAHAVAYVSMAFRIAYFKVHYPLQFYAAYFTIKGDQFDPVLVLKGKEAIKRRLRELKAMTGKDVQKKNEESVLEVVLEMILRGFSFLPPDIFKSDAKKFLIEGNSLRIPFNKLPGLGDSVAESIVRAREEKPFTSVEDLMKRTKVNKNHIELMRSLGVLGSLPETEQFTLF

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Length

1367 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

155.363 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase III PolC-type

Organism

Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995)

Length

1367 amino acids

Function

Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Similarity

Belongs to the DNA polymerase type-C family. PolC subfamily.

Mass

155.335 kDa

Sequence

Protein

DNA polymerase III PolC-type: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)

Length

1286 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

143.304 kDa

Sequence

MADISPRMQEYYDRLNAGLAQAMEVAKTARKTGLDPETVVEIPIANDLADRVEAQVGIPGVAQMIRELEAVMSREEASLHIGDYFAEKKFGETTKEEILDHAIRTAMALLTEGVVSAPIEGIAKVAVKKNDDGSEYLAIYYAGPIRSAGGTAQALSVLVGDYVRRILGMSRYMPREEEIERYIEEIRQYNSIMSLQYLPSEREIRLIISNCPVCIDGEPTEKEEVSGHRNLERVETNTVRGGMALVIAEGLALKAPKVLKNVRKMKMDGWDWLEEMIQATAGSSSSEEKEVGIHPKDKFLRDLIGGRPVFSYPMREGGFRLVYGRSRNTGLAAAGLNPATLHILGDFLAVGTQMKIERPGKAAGISPVDSIQGPTVRLINGDVVRIHDAKRARELSSQVSHIIDVGEILISYGEFMENNHVLVPSAYCESWWRLEGGTTRPADEDEAILQCESGLYLHPDYLYLWDDLKPAEIRSLAEFIHKHGTLADKTLILPLDPTIKEYLERVLCEHQVREGMIRITPCRIVLKCLGLDSSLALSDSWEKELPESALDLVQFLSGMKMRSKAGTRIGGRMGRPGKSKPREMKPAPHVLFPVGEAGGSRRSVQEASKFSYQANTEGGNLQLEMGVRRCPACGTESYKNRCSCGTHTEPVLSCSRCGIEVQGPVCPQCGMEPTSVRQYTVNVRQMLQQAFADLGMRDRDVELVKGVKGLVSRNKPVELIEKGVIRAANKLFVFKDGTVRFDIIDMPLTHFRPREIGVSVERLRELGYLQDIYGVPLQNPDQVLELPPQDILVPEGCGDYLFSCTRFIDTLLEKVYGLPPFYNLETRSDLVGHLVIGLAPHTSAGVLARIIGFSKANVGYGHPFFHAAKRRNCFHGDTLIEIYADGILEEIPIRRFVLEHLDLSQAGVDALGTFYADPVRPAHVRSVDTGGIPHLRKITSVSVHKAPANLIQFSTSRGKNLLVTPDHAMLVWDVSYLRKIRALEVKIGDAVPVWESGVVISDRIVSIDYVPCEDERVYCLTVDRDHNVVGNGIFTGQCDGDEDCVMLLLDGLINFSRSFLPVTRGGSMDAPLVLTSRIDPTEIDKESHNLDVCATYPIEVYETALRYGNAKDVESLVDRVERRLNTPAQIEGFFFTHDTSDISAGPLETMYTQLQSMLDKLDCELSLAKRIRAVDEHDVAERVLKTHFIRDLQGNLSAFSKQKFRCTKCNTSYRRMPLAGKCKCGGNIIPTVHEGSVKKYLQMSRQICEEYNITEYTRQRIEVIDMNIESTFGEEKVEQMGLADFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)

Length

1285 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

142.303 kDa

Sequence

MEVSPAIARYFEELEGELDAAIRLAAAARARGLDPRTEIEIPVASDLADRVEALLGYKGIAARIRELEAEMSREEAALRIGDDFAARKFGETTPEEILDHAIRAAMALLTEGVVAAPTEGIGKVSLGKNDDGTDYLKIYYAGPIRSAGGTAQALSVLVGDYVRQALGINRYIPRPEEVERYIEEIRQYNNIMSLQYLPSEKELRMIIENCPVCIDGEPTEQQEVSGYRNLERVETNTVRGGMALVVAEGLALKAPKVLKNVRKMKMEGWDWIEEMIGGGPKSDDDDASAAIKPKDKYIRDLIGGRPVFSYPMRKGGFRLRLGRARNTGFAAAGFNPATLHILGDFLAVGTQMKVERPGKAAGVVPVDSIQGPTVKLRSGEVRRVDDAAEARRLAGQVDEILDVGEMLVSFGEFMENNHPLMPPAYCEEWWMLEGGPRHPENELEAIEFALDGVPLHPDYTYMWDDVAPADIARLAEAVGTGGTVEDGVLMIRNTPETKAILEELLIPHHLSGDRLAIREHLAFLACLGLTLQLTKRPAWQDAPMENSLDLVMHLSGFTVRSRAGTRIGGRMGRPGKSKPREMRPPPHSLFPIGDEGGARRSFQAACSSKPRSNTDGGVIEAEVGERQCPACGAFTYKNLCECGAHTNPVFRCPRCGKDVGQDVCPRCNAETVCLQKVTINVKAEYLAAMESLGVRESSVALLKGVKGLISRERPVEPIEKGILRALQNLYVFKDGTVRYDMIDLPLTHFRPDEVGVPIERLRELGYTHDTYGRELVSDDQVLELRHQDILVSEGCGEWLVRVAKFVDDLLVRLYGLEPFYKAEKPLDLVGHLLMGLAPHTSAGVLVRLIGFSKAPVGYGHPFFHAAKRRNCFAGDTEITVSDGRRWMSLPIRQFVTENFDISKPGLDHVGTFYSDPRQPFYVRSIDSQGKTSLKRVTSVSVHRAPAHLVRFATRRGRVLTVTPDHAMLVWDTDYLRKIKALEVAVGDRVPVEEGGLVVADEVVSRETVQALDDRVYCLTVAENHTLVANGIFCGQCDGDEDCVMLLLDGLINFSRAYLPETRGGTMDAPLVLTTRIDPSEVDKESHNVDVCDHYPIEVYNGCLAYAHPKDLDAFVDRVERRLGTPAQCEGFLFTHQTSNISAGPLESTYTRLGSMLDKLEAELDLAKRIRAVDEDDVAERVLNTHFIRDLQGNLNAFSKQKVRCMKCNAKYRRMPLAGKCTRCGGHVIPTVHEGSVKKYLEMSRNICATYAISDYTKQRVEVLFMQIESTFGEPPEKQLGLADFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Length

1263 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

143.169 kDa

Sequence

MELPKEIEEYFEMLQREIDKAYEIAKKARSQGKDPSTDVEIPQATDMAGRVESLVGPPGVAQRIRELLKEYDKEIVALKIVDEIIEGKFGDFGSKEKYAEQAVRTALAILTEGIVSAPLEGIADVKIKRNTWADNSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSGKHIERMVEEVDLYHRAVSRLQYHPSPDEVRLAMRNIPIEITGEATDDVEVSHRDVEGVETNQLRGGAILVLAEGVLQKAKKLVKYIDKMGIDGWEWLKEFVEAKEKGEEIEESESKAEESKVETRVEVEKGFYYKLYEKFRAEIAPSEKYAKEIIGGRPLFAGPSENGGFRLRYGRSRVSGFATWSINPATMVLVDEFLAIGTQMKTERPGKGAVVTPATTAEGPIVKLKDGSVVRVDDYNLALKIRDEVEEILYLGDAIIAFGDFVENNQTLLPANYVEEWWIQEFVKAVNEAYEVELRPFEENPRESVEEAAEYLEVDPEFLAKMLYDPLRVKPPVELAIHFSEILEIPLHPYYTLYWNTVNPKDVERLWGVLKDKATIEWGTFRGIKFAKKIEISLDDLGSLKRTLELLGLPHTVREGIVVVDYPWSAALLTPLGNLEWEFKAKPFYTVIDIINENNQIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGSSRDIKKAAEEGKIAEVEIAFFKCPKCGHVGPETLCPECGIRKELIWTCPKCGAEYTNSQAEGYSYSCPKCNVKLKPFTKRKIKPSELLNRAMENVKVYGVDKLKGVMGMTSGWKIAEPLEKGLLRAKNEVYVFKDGTIRFDATDAPITHFRPREIGVSVEKLRELGYTHDFEGKPLVSEDQIVELKPQDVILSKEAGKYLLRVARFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRIIGFVDALVGYAHPYFHAAKRRNCDGDEDSVMLLLDALLNFSRYYLPEKRGGKMDAPLVITTRLDPREVDSEVHNMDVVRYYPLEFYEATYELKSPKELVGVIERVEDRLGKPEMYYGIKFTHDTDDIALGPKMSLYKQLGDMEEKVKRQLTLAERIRAVDQHYVAETILNSHLIPDLRGNLRSFTRQEFRCVKCNTKYRRPPLDGKCPVCGGKIVLTVSKGAIEKYLGTAKMLVANYNVKPYTRQRICLTEKDIDSLFEYLFPEAQLTLIVDPNDICMKMIKERTGETVQGGLLENFNSSGNNGKKIEKKEKKAKEKPKKKKVISLDDFFSKR

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Nanoarchaeum equitans (strain Kin4-M)

Length

1243 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

142.593 kDa

Sequence

MVYYDILAKELEKLYEIAEKARAQGYDPKDIVEIPLANNMGERVAHLISAIHEQLDVKKTAELILELEKQYGFLDWRVGLKLIDYALEGKLIPYDDILKRIDLGVRLALGYITMGVVSAPLEGLVELRIKKRKDGKPYLALYYAGPIRGAGGTAAAVSVLFADYARKKAGLYEYDPTKEEIERYKIEIDSYHNKVARLQYKPSDEEIEFLVKHIPVEINGDPTSDKEVPSYKNLERVETNRIRGGMCLVIAEGIAQKAKKIYGKITEWGKEFGLEHWEFLGEYLKLQKEIQAKLAAESGGEIEGKEIKRKITLFLDEIKKEEITVKYPTPAGKYLQEITAGRPIFSLPMAIGGFRLRYGRSFATGFATSGIHPATMFLTYGFLAIGTQMRGERPKKSTIVTPVTSLHPPIVKLKDGTVKKVHSVVEAIKIANDVEEILFLGDILTAFGDWLNEKANLVPSPYVEEWWIQEFDRAAMKKTDYKIEFDVMKPRKLFKIEGLENLSQYLGIPKDRLEEIIRKPFSRKPTIDEAITISEKLGIPLHPEYTPFWVHITKEELIKLIEELRKAKIQNNKIYFHESQKELKAILEKLFIEHFREGEYFYINESMTKSLLYQLDNLNLEKAKKEFDNAIDALDLVNRLSPIEIRDVAGVYVGFRAGRPEKAKMREMTGRPHGLFPVGEEGGKMRNVIEAYNKGYVKAEFALYYCNHCKRYTIYRKCEVCGNKTKEVYVCKEIINRLKTSLFKQYKDWKKVEEEIASHLWAEAVTHSKNNCREPKRYSLIKLNIKHYVDRAVQKLKLFNIPKLVKGVRGTSNKDHIVERLEKAFLRSVSDVYVNKDGTIRYDGTQIPLTHFRPKDLIGVTIEKLKELGYTHDIYGNPLEREDQILQLKPQDIILPYGILVKSRLNKNKIVRTDAAEAFKKVANFVDEELKRLYNLEPYYNIEKAEDLIGKIVFGIAPHTSAAVVGRIIGFTPIQGIIAHPIWHAGQRRNCDGDETAVMLGLDALINFSREYLPDKRGARTMDAPLVLTLKLELKAVDDEVHDMDIVYNYPLEFYYETLKGSPAKDVKKQCGILTLGDFLKEEDISKIPIGFTHPTKSIRLGNKVSLYKRLKTMQQKTEWQLKLAERIRAVDENIVAEIVIEKHFMPDIKGNLRGFSSQVFRCTKCDTTYDRVPLSGKCPKCGGNIVFTVHEGTIKKYLPTSLYLARKYKIKKFTKQSLFLLDRRIKQIFGGEKKSLADFINS

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)

Length

1240 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

140.145 kDa

Sequence

MNRAREELDRYRETLEEVSSRFVDVATKARQRREDPKPEPEVMLATSIGERVEGLLQVENVADRLEELEEELGDREEATFRIVEEVIKGELKVKGDLPLHKRIDYAVRIGLAVLTEAVVSAPLEGIAAVEIRERGTGHRVVDESEPPHEEPKLVCTECGKEVDPENCYLAVKYAGPIRAAGGTAAALSALLADYARQVAGLPRFNPDDFDHDLVGRYVEEVVTYLDKVGSFQYNPSEEEVELVAKNIPIEIDGEPTEEVEVQGHRDIPHLPNQLRGGALLVICEGICQKAPKLIKRVEKYGIDGWEFLEKLVNKGSDDEEEGEEEKTKIKPNDKYMGELVAGRPLLSHPSAKGGFRLRYGRARNTGFAAVGVHPSLMYVTKGFIVIGTQLKVERPGKAACVLPVTEIEPPVVKLRDGSVVRLDDPREAKELVEKDEIEEILDLGEMLVAVGEFIENNHPLVPPAYCPEWWVKEVPDVVKVIGLRKNLPNDVFEKLKDVPLKRLVKEASRLSGNGNNLDGFLNGPVKVARSIVELVRKEVIPRLSSPERMSVEEAIELSREYGVPFHPKYTFLWHDVKPKDVDELREALEVAGSEWGNLRVEFENDGEIKRILEDLLVPHRLEDDTIVVEEPWASALLAQLGYDPESGEFREQDEDLDYLLDYLVIRDETCRYVSKLAGFPIREKAPTRIGARMGRPEKARERKMSPPPHVLFPIGIAGGNQRDIMKFHRGESEDTDRVEVCYRICPECDRLVPYRVCPFCGTETVQYCNRCDEPADECDCEEPDPVVRADIERNDDPYSSLPVRELVRRAEEEVGTTDTLKGVKGMTSRLKMPEPLQKGILRAKRDLFVFKDGTLRFDCNDCPLTHVRLKEVGLTPFKARLLGFERDINGDPVVSEDQVVELYPQDVVLPRKAAEWAVRVCQYLDDLLRKYYGLEPVYGVEKPEDLIGHLIVTLAPHTSCGVVGRVVGIADINCWYNHPIINAARRRNCDGDEDAFMLLLDVLLNFSRLYLPDKRGGLMDAPLVLTAVVDPYEIDDEVWNMDVCGDYPLELYRKALEYADAGEAEELIERLEDRLDLPRGLQFTHDTEAIDLGPTVTRYSRLEKMEEKLEEQLDLARRIRAVDESDVAKIVLDSHFLPDIKGNLRKFGRQKFRCSRCNAKFNVPPLSGKCPRCGGDVLLTIYPATATKYLEPAKRLVEEFGTHDEEWRTIASEVELLEEEAKTLFGSDHSVSLKKFFGET

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)

Length

1198 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

132.156 kDa

Sequence

MREDDEQYFRRLESDLDTALSVAREARKRGGDPTEDIEIPIAKDMADRVENILGIDGVAERVREMEADPDLSREEAALELAADFANDEVGDYETRAGKVEGAVRTAVALLTEGVVAAPIEGIDRVELLENDDGTEFINIYYAGPIRSAGGTAQALSVLVADYTRTLIGIDEYKARNDETERYAEELSLYDDETGLQYAPKDEETKFIAEHMPIMLDGEATGDEEVSGFRDLERVDTNSARGGMCLVLGEGIAQKAPKIQRYTSQLDEVDWPWLQDLIDGTYKTGEDTDEADADSDDGTDEDAADDSDIDDSSAGDEEADAPSGPPRPDPQKKFLRDLIAGRPVFGHPSEPGGFRLRYGRARNHGFATAGVHPAAMHLIDDFLATGTQIKTERPGKAAGVVPVDTIEGPTVKLANGDVRRVDDPEEALEIRNGVEAILDLGEYLVNYGEFVENNHPLSPAAYAPEWWTQDLAAAGADVQALADSPRVDLEHPSAEQALEWAERYDAPLHPEYTYLWHDLDVERFEALAAAASEGHWAETDGAQQTRPPDGAAESTLVVPRSEPVREALEVLLVEHTQGEETLTVPDAEPLVRSLGLTEGLERTWDELSTAARSYDDGDNAVRAVNEVAPFEVRERAPTRIGCRMGRPEKSEKRDLSPAVHTLFPIGEAGGSQRDIAEAATHAESMQDTPGEVEVQVGRRQCPACDTETFRARCPDCESVTDPRYVCYDCNIDVDPDESGRAICPNCEREADAVQNRTVNVHEEYRSALSNVGERENAFDVLKGVKGLSSEHKVPEPIEKGVLRAKHGVSAFKDGTVRYDMTDLPVTSVRAAELDVTADQLRSLGYETDIHGEPLTHEDQLVELRVQDVVLSNGAAEHMLRTADFVDDLLEQYYGLEPFYDAEDRDDIVGELVFGMAPHTSAAVVGRVIGFTSAAVGYAHPYFHAAKRRNCDGDEDCVMLLLDGLLNFSKTFLPDQRGGRMDAPLVMSSRIDPAEIDDEAHNMDIVSSYPRAFFEATREMADPGEVESLIQLGEDTLGTADEYRGFEHTHDTVDLAAGPDLSAYKTLGDMMEKMDAQLELSRKLRSVDETDVAERVIEYHFLPDIIGNLRAFSRQETRCLDCGEKYRRVPLTGDCRECGGRVNLTVHQGSVNKYIDTAIQVAEEYGCREYTKQRLRILDRAVESIFEDDTNKQSGIADFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)

Length

1152 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.786 kDa

Sequence

MGETIASEEMHRYFDGLEARLKEAIEIANRARARGGDPRPVVEIPLAKDLADRVENLIGVKGVAEKIRELEARMSREEAALEIGKQVAEGVVGSFPSKKDAVEAAIRVSMAVLTEGVVAAPIEGIDKVDLGKNDDGSQYIRIFYSGPIRSAGGTAQALSVLVGDYVRRGIGIDRYKPREEEVERYVEEILLYKRVASLQYTPSEDEIRLIVRNCPVCIDGDPTEEAEVEGHRDLERIGTNRVRGGMCLVLAEGLALKAPKVKKHVNKLKMDGWDWLETLIGGAKSGESDEDEQKNKIKPKDKYIRDLIAGRPVFSHPSRPGGFRLRYGRSRNTSFASAGINPAGMVLLDDFITNGTQLKIERPGKAAAMSAVDSIEGPTVRLFSGDLIRVDDIKEAYEVRQQVEVIVDIGEILINYGDFLENNHPLMPSPYVFEWWIYDYESVCSEKILEKDLKNPSASLALKLAEKYNVPLHPKFTYLWHDINRNEFEALRKFVAEKGTFLEGEGEGEGEGILKLPLEDSVKEGIKPVLEKLLVLHKVKEGGIFVEEALPFILCLGLDRSLKEKVSMPDTGDMVEAAGILSGFKVYPKAPSRIGARMGRPEKSDLRKMSPAAQVLFPISNAGGMTRNLVSASDYTSCMNAKIGEIEVELGLRECPACGKESYFWRCECGEFTNPKLSCPRCKIDVRGAETCPKCGRKPTSVANVKLDFRPIYKQAFENVGERERMDIIKGVKRLMNGQMTPEPLEKGILRAKHDVYIFKDGTVRYDMSDIPLTHIRADELGITAARLRELDYKEDIYGKPLERDDQVVCLKVQDLLLSYDGAEYMLRTAKYVDELLVKYYKVEPYYNAETIQDLVGVLMIGLAPHTSAGVLGRLIGFTKASVGYAHPFFHASKRRNCDGDEDCVMLLMDGILNFSRSYLPEKRGGKMDAPLVLTTRIDPKEVDKEAHNIDLLARYPLEFYRATQEIKNPTEIESIMDLVSSRLGKPDQYEHFMFTHDTSNIAAGPLKSSYKTLGSMIEKMEAQLSLAGKIRAVDAPDVAERVLKSHFLPDLIGNLRSFSRQRMRCIKCGEKFRRPPLTGACPKCGGNVVLTVHEGAVRKYLEISKEIGERYGVSSYTRQRIELLDYDICSLFENHKVKQLGLSDFMSGSAR

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanosarcina barkeri (strain Fusaro / DSM 804)

Length

1146 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.094 kDa

Sequence

MGETIASKEMHEYFDELEARLKKAIEIANTARARGGDPKPVVEIPLAKDLADRVENLIGVEGVAAKIRVLEEKMSREECALEIGRQVAEGEVGNFATKKDAVEAAIRVSMAVITEGVVAAPIEGINKVELGKNDDGSEYIRIFYSGPIRSAGGTAQALSVLVGDYVRRGIGIDRYKPRPEEVERYVEEIVLYKRVASLQYMPSEDEIRLIVKNCPVCIDGDPTEEAEVEGHRNLERIGTNRIRGGMCLVLAEGLALKAPKVKKHVNKLNMDGWDWLDILIGGAKTGGDEEDEKKNKIKPKDKYIRDLIAGRPVFSHPSRPGGFRLRYGRSRNTSFAAAGINPSTMVLLDDFITNGTQLKVERPGKAAAMSAVDSIEGPTVRLYSGDLVRIDDIKEAYELRSQVEVIVDIGEILINYGDFLENNHPLMPSPYVFEWWRYDYEAACSEIIPEDELKDPSSALALRLAEEYDVPLHPKFTYLWHDINRTEFEALRKFVVGRGNFSVEDEILRLPLKACIENGVKLILEKLLVLHRVKADTILIKEALPFILCLGLDCHLKEKAPMPDTDNMVNATAFLSGFKVLPRAPSRIGARMGRPEKANLRKMSPAAQVLFPIGNAGGLTRNLVSASNYSVSMNGKIGEIEVEMGIRECPACGKETYFWRCDCGEYTRPKLFCPRCKIEVRNSETCPKCGRKPTSVSNVKLDFRSIYKRAFENVGEREKMDLIKGVKRLMNGQMTPEPLEKGILRAKHDVYIFKDGTVRYDMSDIPLTHVRADEIGITAAKLRELGYVEDIYGNPLERDDQIVCLKVQDLVISYDGGGYMLRTAQYVDDLLVKYYGVEPYYNAKTIQDLVGVLLIGLAPHTSAGVLGRLIGFTRASVGYAHPFFHASKRRNCDGDEDCVMLLMDGILNFSRAYLPEKRGGKMDAPLVLTTRIDPKEVDKEAHNIDLPARYPLEFYRATQEIKNPTELEGIMDLVSSRLGTPEQYEHFMFTHDTSDIAAGPLNSSYKTLGSMIDKMEAQLSLANKIRAVDAPDVAERVLKSHFLPDLLGNLRSFSRQRMRCIKCGAKFRRPPLTGACPKCGGNVVLTVHEGAVRKYLEISKEIGKRYGVSSYTQQRIELLDKDICSLFENHRVKQLGISDFMSGSAR

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)

Length

1145 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

127.679 kDa

Sequence

MGETIASEEMHEYFDGLEARLKEAIEIANRARAQGGDPKPTVEIPLAKDLADRVENLIGVQGVAAKIRELETRMSREEAALEIGKQVAEGVVGSFPTKKDAVEAAIRVSMATLTEGVVAAPIEGIDKVELGKNDDGSQYIRIFYSGPIRSAGGTAQALSVLVGDYVRRGIGIDRYKPREEEVERYVEEILLYKRVASLQYTPSEDEIRLIVRNCPVCIDGDPTEEAEVEGHRDLERIGTNRVRGGMCLVLAEGLALKAPKVKKHVNKLKMDGWDWLETLIGGAKSGGSAEDEQKSKIKPKDKYIRDLIAGRPVFSHPSRPGGFRLRYGRSRNTSFASAGINPASMVLLDDFITNGTQLKVERPGKAAAMSAVDSIEGPTVRLFSGDLVRIDNIKEAYELRPQVESIVDIGEILINYGDFLENNHPLMPSPYVFEWWQYDYEAACPEKTPEEELKNPSSALALRLAEEYNVPLHPTFTYLWHDINRNEFEALRKFVVEKGTFDGEGTLKLPLTASFEEGIKPLLEKLLVLHRVKEDKILVEEALPFVLCLGLDSSLKEKAGMPDTDDMVEAAGVLSGFKVYPRAPSRIGARMGRPEKSDLRKMSPAAQVLFPINNCGGITRNLVSASDYTSCMNGKIGEIEVELGLRECPACGKETYFWRCECGEFTNPKLSCPRCKIDVRGAETCPKCGRKPTSVANVKLDFRSVYKQAFENVGEREKMDLIKGVKRLMNGQMTPEPLEKGILRAKHDVYIFKDGTVRYDMSDIPLTHIRADELGITATKLLELGYREDIYGNPLERDDQVVCLKVQDLVISYDGGEYMLRTAKYVDDLLVKYYKVGPYYNAETIQDLVGVLLIGLAPHTSAGVLGRLIGFTKASVGYAHPFFHASKRRNCDGDEDCIMLLMDGILNFSRSYLPDKRGGKMDAPLVLTTRIDPKEVDKEAHNIDVPARYPLEFYRATQEIKNPTELESIMDLISGRLGTPEQYEHFMFTHDTSDIAAGPLNSSYKTLGSMIEKMEAQLSLANRIRAVDAPDVAERVLKSHFLPDLIGNLRSFSRQRMRCIKCGEKFRRPPLTGACPKCGGNVVLTVHEGAVRKYLEISKEIGERYGVSSYTRQRIELLDYDICSLFENHKVKQLGLSDFMSGSAR

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)

Length

1145 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

127.582 kDa

Sequence

MAEIVASDEMNEYFNTLEGTLKKEIDIVNDARSRGKDPKPHVEIPLAKDLADRVENLIGVKGVAELIRKLEETMSREEAALALGREVAQGKVGEFDSKSEAIEAAIRVSVAMLTEGVVAAPIEGIDRASIGKNDDGSEYVSIFYAGPIRSAGGTAQALSVLVGDYVRRGVGIDRYKPRKEEVERYIEEIMLYKRVASLQYTPSEEEIRLIVENCPICIDGEPTEAEEVEGHRNLERIDTNRVRGGMALVLAEGLALKAPKIQKHVKNLKIDGWEWLEQLISGVKSSSESDEDEETDGKPKIKPKDKYMRDLIAGRPVFSHPSRPGGFRLRYGRSRNTSFAAAGISPAGMIVMDDFIAPGTQLKVERPGKAAGMAPVDSIEGPTVRLNNGDVIRIDTIDEAYALRSEVEEIIDIGEILINYGDFLENNHPLAPSPYCFEWWIQEYRKAAPDTETNEAELKEPTQEVALDLCKELNIPLHPKFTYLWHDIDNSQYTALADLISKDGLLEADGSFLKLPLQRTIDTGMKKVLEDLLVQHKIQGQALTIEEPLPLIHSLGLDEELSKGWDSLGHEELLENINEIAGFVVRPRAPTRIGARMGRPEKSDKRKMTPAPHALFPIAEAGGNTRSLEKAANFKVNTNSKAGTIPVEIGNRICPACGVEGFEFRCECGEYTLPKLFCPRCGISVNKEKCPKCNSKTTCTSMRKIDFKSIYQKAFESIGERDHLDSFKGVKKMMSKHMTPEPLEKGILRAKHGLFTFKDGTVRYDMSDIPLTHIRPAEIGVSCERMIELGYLKDIYGKPLIDSEQVLCLKVQDLVISYDAADYILRITQYIDDLLVKYYKVAPYYNAKHIDDIVGVLLMGLAPHTSAGVLGRLIGFTTASVGYAHPYFHAAKRRNCDGDEDCVMLLMDGLLNFSRDYLPDKRGGQMDAPLVLTTRLDPSEVDKEAHNIDMCASYPLEFYEATQNIANPKDFEGTMDLVSGRLGTTLQYEEFMFTHDTSNIAAGPLKSAYKTLGTMVEKMDAQLELAKKIRAVDAPDVAERVLTSHFLPDMFGNLRAFSRQRTRCVKCAAKFRRPPLTGSCPKCGGRVILTVHEGAVKKYLQVSIKIAEEYNVSSYTKQRIELIGYDMKSLFENDKSKQMGLSDFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Length

1143 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

129.368 kDa

Sequence

MDATLDRFFPLFESESNEDFWRIEEIRRYHESLMVELDRIYRIAEAARKKGLDPELSVEIPIAKNMAERVEKLMNLQGLAKRIMELEEGGLSRELICFKVADEIVEGKFGEMPKEEAIDKAVRTAVAIMTEGVVAAPIEGIARVRIDRENFLRVYYAGPIRSAGGTAQVISVLVADYVRRKAEIGRYVPTEEEILRYCEEIPLYKKVANLQYLPSDEEIRLIVSNCPICIDGEPTESAEVSGYRNLPRVETNRVRGGMALVIAEGIALKAPKLKKMVDEVGIEGWEWLDALIKGGGDSGSEEEKAVIKPKDKYLSDIVAGRPVLSHPSRKGGFRLRYGRARNSGFATVGVNPATMYLLEFVAVGTQLKVERPGKAGGVVPVSTIEGPTVRLKNGDVVKINTLSEAKALKGEVAAILDLGEILINYGDFLENNHPLIPASYTYEWWIQEAEKAGLRGDYRKISEEEALKLCDEFHVPLHPDYTYLWHDISVEDYRYLRNFVSDNGKIEGKHGKSVLLLPYDSRVKEILEALLLEHKVRESFIVIETWRAFIRCLGLDEKLSKVSEVSGKDVLEIVNGISGIKVRPKALSRIGARMGRPEKAKERKMSPPPHILFPVGMAGGNTRDIKNAINYTKSYNAKKGEIEVEIAIRKCPQCGKETFWLKCDVCGELTEQLYYCPSCRMKNTSSVCESCGRECEGYMKRKVDLRELYEEAIANLGEYDSFDTIKGVKGMTSKTKIPERLEKGILRVKHGVFVFKDGTARFDATDLPITHFKPAEIGVSVEKLRELGYERDYKGAELKNENQIVELKPQDVILPKSGAEYLLRVANFIDDLLVKFYKMEPFYNAKSVEDLIGHLVIGLAPHTSAGVLGRIIGFSDVLAGYAHPYFHAAKRRNCDGDEDCFMLLLDGLLNFSRKFLPDKRGGQMDAPLVLTAIVDPREVDKEVHNMDIVERYPLEFYEATMRFASPKEMEDYVEKVKDRLKDESRFCGLFFTHDTENIAAGVKESAYKSLKTMQDKVYRQMELARMIVAVDEHDVAERVINVHFLPDIIGNLRAFSRQEFRCTRCNTKYRRIPLVGKCLKCGNKLTLTVHSSSIMKYLELSKFLCENFNVSSYTKQRLMLLEQEIKSMFENGTEKQVSISDFV

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)

Length

1141 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

126.42 kDa

Sequence

MAELVTSPAYRAYLDGLIAGLDRAMEIANKAKSLGVDPRPYVEIPIASDLAGRVEALLGYKGVAAKIRELEDRMSREEAALKIGDAFVGKEFGESTREDILDHAIRTSMALLTEGVVAAPTEGIGKVAVRRNDDGTEYLSIYYAGPIRSAGGTAQALSVLVGDYVRRLLNIDRYKPREEEIERYVEEIKQYNNIQSMQYLPKDDDIRLIIRNCPICIDGEPTEQEEISGYRNLERVETNVVRGGMGLVIAEGIGLKAPKIQKNVAKMNLDGWEWLEELISGNTPAQEVEEEPGVHPKDKYMRDMLAGRPSFSYPMRKGGFRFRLGRCRNTGLATCGFNPATLHILDDYLAVGTQMKVERPGKACGVVPCTDIEGPTVRLKSGELRRIDTLDDANKYYDQVEYILDIGEILISFGEFMENNHVLMPPSYCEEWWIQEGGPRHPKNEAEALSFVLEGAYLHPDYTWFWDDCSEGQLIFLSDKVAGTGSLREGVLYIPEDPAVKSVLEELLVPHTVEEGFYVVRTPLALIMGLGLTDTLAKSPTWKTLPPFSNGLSMAISLSGLKMRSKAGTRVGGRMGRPGKSAPRKMKPPVHVLFPIGESGGMKRSIDNAAKICSSDSEENFRGTSVTTGQVEGLIQVQTGERRCPKCGTVTFKSRCADCGTHTDAVYRCPHCNQLGEEGQESCPKCGANLVCSKESIVSLGQEYAAALKNVGMSASSSPELKGVRGLISRERVVEPLEKGLLRAKNNIFVFRDGTIRYDMIDLPLTHFRPAEVGVSVEKLRSIGYTQDMHGADLTDASQLVELHPQDIMVSVDCGEYLVRVAAYVDELLEKVYGMEAFYHVKTPEDLVGHLVMGLAPHTSAGVLARIVGFTKAKAGYAHPYYHAAKRRNCDGDEDCVMLLMDGLLNFSRSFLPSTRGGTMDAPLVLTTTLNPKEVDKETLNVDVMPRYPLEVYTACLTYRAPKEVGKFVDYVEKRVETPGQFEGFSFTHDTTDISEGPIDTMYTNPILKGTADKIKAELGLADRIRAVDTNDLAERIINSHLMPDMIGNLRSFSKQAFRCPKCKTSYRRIPVSGKCNKCGGPVKATMHKGNVTKYLEISKYMAEHYTLSDYTNQRIQVTEMNINSTFGEEEKVQMDLSDFF

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

Length

1139 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

129.402 kDa

Sequence

MIVMVHVACSENMKKYFENIVDEVKKIYRIAEECRKKGFDPTDEVEIPLAADMADRVEGLVGPKGVAERIRELVKELGKEPAALEIAKEIVEGKFGNFDKEKKAEQAVRTALAVLTEGIVAAPLEGIADVKIKKNPDGTEYLAIYYAGPIRSAGGTAQALSVLVGDFVRKAMGLDRYKPTEDEIERYVEEVELYQSEVGSFQYNPTADEIRTAIRNIPIEITGEATDDVEVSGHRDLPRVETNQLRGGALLVLVEGVLLKAPKILRHVDKLGIEGWDWLKDLMSKKEEKEEEKDEKVDDEEIDEEEEEISGYWRDVKIEANKKFISEVIAGRPVFAHPSKVGGFRLRYGRSRNTGFATQGFHPALMYLVDEFMAVGTQLKTERPGKATCVVPVDSIEPPIVKLKNGDVIRVDTIEKAMDVRNRVEEILFLGDVLVNYGDFLENNHPLLPSCWCEEWYEKILIANNIEYDKDFIKNPKPEEAVKFALETKTPLHPRFTYHWHDVSKEDIILLRNWLLKGKEDSLEGKKVWIVDLEIEEDKKAKRILELIGCCHLVRNKKVIIEEYYPLLYSLGFDVENKKDLVENIEKILESAKNSMHLINLLAPFEVRRNTYVYVGARMGRPEKAAPRKMKPPVNGLFPIGNAGGQVRLINKAVEENNTDDVDVSYTRCPNCGKISLYRVCPFCGTKVELDNFGRIKAPLKDYWYAALKRLGINKPGDVKCIKGMTSKQKIVEPLEKAILRAINEVYVFKDGTTRFDCTDVPVTHFKPNEINVTVEKLRELGYDKDIYGNELVDGEQVVELKPQDVIIPESCAEYFVKVANFIDDLLEKFYKVERFYNVKKKEDLIGHLVIGMAPHTSAGMVGRIIGYTKANVGYAHPYFHAAKRRNCDGDEDSFFLLLDAFLNFSKKFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDTMWSYPLEFYEKTLEMPSPKEVKEFMETVEDRLGKPEQYEGIGYTHETSRIDLGPKVCAYKTLGSMLEKTTSQLSVAKKIRATDERDVAEKVIQSHFIPDLIGNLRAFSRQAVRCKCGAKYRRIPLKGKCPKCGSNLILTVSKGAVEKYMDVAEKMAEEYNVNDYIKQRLKIIKEGINSIFENEKSRQVKLSDFFKIG

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)

Length

1134 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

126.003 kDa

Sequence

MPPKTSEAQEAYFKKLEAEFLHCREIATAARRKGYDPSLEVEIPSATDLADRVEVIMGVPGLAAHIRKCEEKMSREEASLQVAADIAEGLVGKFKDEEEAVQCAVRTAVAVLTEGVVAAPLEGISAVKLAKNDDGTEYIKVYFAGPIRSAGGTAEALAVLAADYVRRKTGRAPYKIRDVEVERFVEEIMLYKSIAHLQYTPTDEEIRLIVRNCPVCIDGEPTEQEEVQGYRNLERVETNRVRGGIALVIAEGIILKAPKVKKHVDKLKFDGWEWLDKIIAGSKPAGGENKEEEKKIKPKDKFLADLIAGRPVFGHPSRAGGFRLRYGRSRNTGFATAGIHPASMTIMDDFIATGTQLKVERPGKAAAMVPVDSLEGPTVRLFNGDVVRISDEKTALKVRPDVSQILDNGEIIINYGDFLENNHTFVPSPYVEEWWIQDLEEKTKDKVEVNSPEEAFAVSEKYGVPLHPKYTYMWMDLTTDDVVYLARYISASGMVENGELRLPVEQRSKSLLEILLIPQKVRDNTVILSAEDTYILCRCLGLNPDLSMKNPDAYAGLDSHAWKAVSALCGVTVMDRAPARIGARMGRPEKSKLREMKPPVHVLFPVGEAGGMRRSLQDASAYSKSMTDRIGEIEVEVGRRKCPDCGKMTYMVACECGGHTIPVYGCPDCGISGIEGDCPKCHKPTTPNVKQKIDVKGLYAAALKRVGERDNFEVLKGVQGLISKEKTPEPLEKGILRAKHEVFVFKDGTIRYDMSDVPLTHFIPREIGLSVEKARELGYEKDTYGAPLESPEQVCELRVQDIILSHDASNYLLKVCAFLDDELEKYYGLPRYYNVHEEQDLIGHLVIGLAPHTSAGVLGRIIGFVSSSAGYAHPFFHAAKRRNCDGDEDCVMMLMDGLLNFSLSYLPDRRGGKMDAPLVLSMRIDPKEIDKESHNIDVMARYPKEFYLATREFKAPKDVEKIMDLVSKRLGTPEQYEGFKFTHGTSDIAAGPANSAYKTLGSMEDKLKAQLELGRRLRAVDEKDVAERVINSHFLPDLIGNLRAFSTQQMRCVKCGERYRRPPLTGTCPRCGGGRVILTVHEGAVTKYMDVSLAIAKEYGVPSYTIQRLELLSLSIKSLFENDKSKQTGLADFM

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanococcus maripaludis (strain C5 / ATCC BAA-1333)

Length

1131 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.289 kDa

Sequence

MLHVSASKGMTEYFKNILDNVKNLYDLAEGCRKSGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSDLGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAHVKIKKNNDGGEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDKFKPTDDEVERYGEEVDLYQSEVTTFQYQPKAEEIRVAVRNISVEITGEATDDVEVSGHRDLPRIETNQIRGGALLALVEGVLLKAPKILRHVDKLGIEGWDWLKELKSKKEELVEEIEEENDEFNYEEEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVKLNDKSVLKIDTVEKAKQYRDDVEEILFLGDILVNYGDFLENNHTILPSSWCTEWYEKILKSENLEYTKEFIENPDQKEVVKYAKLTNTPLHPKYTYFWHDISKDNINVLRNWIIGGRYNESNDSWGLTYDPEDPEISIVKRYLELIGCPHTVVDEKVEIFEYYPLLYSLGYDFDEKQDVVEDIEEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAASRKMKPPVNGLFPIGNAGALVRLINKAVDEGKTDEIEISNVKCSCGNVSLYRTCPFCGSSVEPSGPSRIKLPIKEYWYKALENLKINKAGDVKCIKGMTSKDKIIEPLEKAILRAKNDIFVFKDGTTRFDCTDVPVTHFRPVEIHGDIEKLKSLGYLKDIHGNPLENENQVLELNVQDVIVPESCMDYFLNVSKFIDDLLEKYYKKDRFYNVNKREELVGHLIIGMAPHTSAGMVGRIIGYSKANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEGIAPKEIKKIMETVEDRLDKESQYEGIGYTHETLKIDEGPLVCAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGICRKCGSRLILTVSKGAVEKYMDVSQTMAEKYNASDYIKQRLEIIRSGIDSLFVNDKRKQVKIEDFFK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanococcus maripaludis (strain C6 / ATCC BAA-1332)

Length

1131 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.285 kDa

Sequence

MLHVSASKGMAEYFKNILDNVTELYTLADDCRKSGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSDLGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAHVKIKKNNDGSEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDKFKPTEDEVERYGEEVDLYQSEVTTFQYQPKAEEIRVAVRNISVEITGEATDDVEVSGHRDLPRVETNQIRGGALLALVEGVLLKAPKILRHVDKLGIEGWDWLKELKSKKEEVIEEIEEEKDDFNYEEEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVKLNDKSVLKIDTVEKAKQYRDDVEEILFLGDILVNYGDFLENNHTILPSSWCVEWYEKILKSENLEYTKEFIENPDQKEAVTYAKLTKTPLHPKYTYFWHDISKDNINVLRNWLIGGKYNENNDSWELTYNLEDSEIATSKRYLELIGCPHTVTAETVEIFEYYPLLYSLGYDFDKKQDIVEDIGEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAASRKMKPPVNGLFPIGNAGALVRLINKAVEEGKTDEIEISNVKCSCGNVSLYRTCPFCGSSVEPSGPSRIKLPIKEYWYKALENLKINKAGDVKCIKGMTSKDKIIEPLEKAILRAKNDIFVFKDGTTRFDCTDVPVTHFRPVEIHVGIEKLKFLGYLKDIHGNPLENENQVLELKVQDVIVPESCMDYFFNVSKFIDDLLEKYYKKDRFYNVNKREELVGHLIIGMAPHTSAGMVGRIIGYSYANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEGIAPKEIKKIMQTVEDRLDKDSQYEGIGYTHETLKIDEGPLVCAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGVCRKCGSRLILTVSKGAVEKYMDVSQTMAEKYNASDYIKQRLEIIRSGIDSLFVNDKRKQVKIEDFFK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanococcus maripaludis (strain C7 / ATCC BAA-1331)

Length

1131 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.38 kDa

Sequence

MLHVSASKGMTEYFKNILDNVTELYTLADDCRKSGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSDLGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAHVKIKKNNDSGEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDKFKPTEDEVERYGEEVDLYQSEVTTFQYQPKAEEIRAAVRNISVEITGEATDDVEVSGHRDLPRVETNQIRGGALLALVEGVLLKAPKILRHVDKLGIEGWDWLKELKSKKEEVIEEIEEEKDDFNYEEEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVRLKDKSVLKIDTVEKAKQYRDDVEEILFLGDILVNYGDFLENNHTILPSSWCTEWYEKILKSENLEYKKEFIENPDQKEAVNYAKLTKTPLHPKYTYFWHDISKDNINVLRNWIIGGKYNESNDSWEVTYDSENPEISNAKRYLELIGCPHTVTGEKLEIFEYYPLLYSLGYDFDEKRDIVEEIEEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAASRKMKPPVNGLFPIGNAGALVRLINKAVEEGKTDEIEISNVKCSCGNVSLYRTCPFCGNSVEPSGPSRIKLPIKEYWYKALENLKINKAGDVKCIKGMTSKDKIIEPLEKAILRAKNDIYVFKDGTTRFDCTDVPVTHFRPVEIHVGIEKLKSLGYLKDIHGNSLENEDQVLELKVQDVIVPESCMDYFFNVSKFIDDLLEKYYKKDRFYNVNKRDDLVGHLIIGMAPHTSAGMVGRIIGYSNANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPIEFYEKSLEGIAPKEIKKIMQTVEDRLDKDSQYEGIGYTHETLKIDEGPLVCAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGVCRKCGSRLILTVSKGAVEKYMDVSQTMAEKYEASDYIKQRLEIIRSGIDSLFVNDKRKQVKIEDFFK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanococcus maripaludis (strain S2 / LL)

Length

1131 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.381 kDa

Sequence

MLHVSASKGMTEYFKNILDDVSNLYNLAEECRKNGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSEFGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAYVKIKKNSDNSEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDRFKPTEDEVERYGEEVDLYQSEVTTFQYQPKAEEIRVAVRNISVEITGEATDDVEVSGHRDLPRVETNQIRGGALLALVEGVLLKAPKILRHVDKLNIEGWNWLKELKSKKEEVIEELEEENDEYNYEDEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVKLNDGSVLKIDTVEKAKQYTDEVQEILFLGDILVNYGDFLENNHTVLPSSWCTEWYEKILKSQNLEYTEEFIKNPGQKEAVNYAKITKTPLHPKYTYFWHDISKENISTLRSWVIGGKYNPSNDSWELNYDPEDEEISNAKRYLELIGCPHIVMEEKVEIFEYYPFLYSLGYDFDEKRDMIDNIDEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAAARKMKPPVNGLFPIGNAGALVRLINKAVDEGKTDEIEIANVKCSCGKVSLYRTCPFCGNSVEPTGPSRIKLPIKDYWYKTLENLKINKPGDVKCIKGMTSKDKIIEPLEKAILRAKNNIYVFKDGTTRFDCTDVPVTHFKPVEIHVPIEKLKSLGYLKDIHGNPLENEDQVLELKVQDVIVPESCMDYFLNVSGFIDDLLEKYYKKDRFYNVNTREDLVGHLIIGMAPHTSAGMVGRIIGYSNANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEGIAPKEIKKMMETIEDRLDKDSQYEGIGYTHETSKIDEGPPICAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGVCRKCGSRLILTVSKGAVEKYMNVSQTMAEKYDASDYIKQRLEIIKSGIDSLFVNDKRKQVKIEDFFK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)

Length

1131 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

128.607 kDa

Sequence

MLHVSASKNMTEYFKSILNDVNNLYFIAEECRKLGYDVVDKVEIPLAKDMADRVEGIVGPPKVSERIRELVMELGKEPAALEIAKEIVEGRFGEFGKEEGAEQAVRTALAVITEGIVAAPLEGIAHVKIKKNHDGTEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMNLDKFKPTDDEVERYGEEIDLYQSEVTTFQYQPKIEEIRTAVRNISVEITGEATDDVEVSGHRDLERVETNQIRGGALLALVEGVLLKAPKILRHVDKLEIEGWNWLKELKNKKEEINEDIKDEKEDFNYEEEEDLSQYDDCEIEEVTKFIGEVIAGRPVFAHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIDPPIVKLNNHSVLKIDTVEKAIKYRKDVLEILFLGDILVNYGDFLENNHVMLPSSWCVEWYEKILKVNNIPYSTEFISNPSPKEAVKFAITTKTPLHPVYTYHWHDISKENIYSLRNWILRGNFNKNSDKWEISYDLENPEDISNKRFLELIGCCHEVVDGKIFILEYYPLLYSLGYDYENSFDSVENLEEKVSNAKNNMHLINLLSHFEIRRNTYIYVGARMGRPEKAASRKMKPPVNGLFPIGNAGALVRLINKAVEGGKTDEIEISNVMCSCGKVSLYKKCPFCGKSVIPTGPTRIKLPIKDYWYNALENLKINKPGDVKCIKGMTSKDKIIEPLEKAILRAVNDVYVFKDGTTRFDCTDVPVTHFKPCEINVSVNRLKELGYLRDINGNSLENDKQVLELKVQDVIVPESCMDYFLNVSKFIDDLLEKYYKKNRYYNSSNKEDLVGHLIIGMAPHTSAGMVGRIVGYSKANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFLNFSKKFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEMVTPKEIKKLMETVEDRLGKDEQYEGIGYTHETLKIDEGPLICSYKTLGSMMDKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRIPLKGVCRKCGSRLILTVSKGAVEKYMNVSQTMAEKYNVSDYIKQRLEIIRSGIDSLFTNDKRKQVKIEDFFK

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)

Length

1117 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

124.988 kDa

Sequence

MDYFGMLEEKTKELYAIAREARKQGKDLELEPEIPLAKDLAERVEGLVGPEGVAKRIKELEKSMSREEVAFQIAKEIATKDDVEGQPNDYEVQEANADSAIRTALAILTEGVVAAPLEGIAKVKIKDNSDGTKCFGVYFAGPIRSAGGTAAALAVLLGDYIRMSQGLDRYKPTDDEIERYVEEVELYESEVTNLQYSPTPDEVRLAIRGIPVEVTGEQTDPVEVQNRDLPRVETNNLRGGALLAVAEGVIQKSRKIVKYAKTLKIDGWDWLEYFTAPKSTKEEEKKKEESSENKPKKKAKYMEDIIGGRPVMSYPGAKGGFRLRYGRTRDSGLASMAIHPATMEIVEFLAIGTQMKIEKPGKGNCVVPCDSIEGPIVKLKNGDVIQVNDVSKAISIRRDVNEIIFLGDMLVAFGEYLRGNIPLDVSAWCEEWWAQEIEASEYFKETHDTFGIDFNENMELNALLKLDIDAKKAFDIAKKTNTPLHPKFTFYYNDVTKEELNDLHNYLYSLIDSPEDVFKSDMNRIPIDYHKRIIEVLGIPHHVNNKSLIMSNDNLYTLMSVLNKSLSPDEDMETIEAVNMISPVSIKSKAPTYIGGRVGRPEKTKERLMKPAPHSLFPIGNYAGNIRNIVEAAKKGTIKVTLAKCKCTNPDCKVSSFKALCPVCGSRTELESSAAKNIKLDKLLMDAFENVNVRRLDEVKGVKGLISEDKYPEPLEKGILRARNDVFTYRDGTIRHDSTDLPLTHFIPREVGVPYEKILEMGYTEDIYGKPITNDNQIIEIKIQDIVVSESCGDYLLKVSKFIDDLLIRYYHMEPFYNAENRVDLVGHLIAGLAPHTSAGVLGRIVGFTKASCCYAHPYFHSAKRRNCDSDEDAVMLLLDALLNFGKTYLPSTRGGSMDAPLVLSIRIDPEEIDDESHNIDCMKRIPLEIYHKTEEGGVKPSDVNDLVDNVESRLGTDNQYHGLMYSHPTSSIHAGPKICLYKTLQTMTDKVESQIALAELLRAVDQKGVVEGVLNSHFLPDMAGNIRAFSRQKVRCTKCGAKYRRIPLSGECTCGNNLILSISKGSVLKYLDISKDLSHRYPINPYVVERIEILETGINSLFESDKSKQSSLDAFF

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Cenarchaeum symbiosum (strain A)

Length

1112 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

121.039 kDa

Sequence

MSGGDVEEYLRGADMPEEYRRYYSSLSGGTYDIFEKAASAKSNLADSSGMVEPKIAVDLSDRVAKMHDLDIAGPLRELLATKGKELAALMLAKEIMDGKYLPEADIEKRIDSAVRVGLAVVTEGVTIAPLQGIADVITKKNKDGSEYLSVSIAGPMRSAGGTESAVTMLIADYVRRQAGLAEYQADSLDDETGRFIEELRIYEREVGSFQFHVLDEDIRAVISHLPVELDGVDTDPYEVVNHKGMSRIQTDRVRGGALRVLNDGLIGRSKKLLKRIELYGLDGWEWLAELKGAVQTGENKEDAAAKRMREVITGRSVLSMPNRLGGFRLRYGRACNTGYTSVGFHPAVAEILDHTIAVGTQVKIDIPGKGATVAFVDTIEAPTVRLAGGDVVKIRDVAHGIELKGSIERILHLGDMLISFGDFLENNAQLVPSGYVEEIWKMDMEAAGAAQGSPSSADEAVRISRELGVPLHPRYLYYWDQISHEELAMLLSPLDKGDAISYPAACKPVLEKLGVPHKAGPEGPVLEGDEARIFRELILDNPPGPDASAPVPELISRSSGITIRDKFSTSIGVRIGRPEKAAPRQMRPPTHCLFPVGGTGGPTNNLLKSAARPGFSADILSRRCPGCGEPSISIRCWACGERTAVERTCMQCGTDVDGEECERCGRPGLAHSRVEFPLKKMLVSAQEKTGVRAHDPLKGVKELAHQDRIAEPLEKGLIRQSRSLTVFKDGTVRFDATNSPMTHFKPSWIGTSAEKLRELGYETDVDGKKLEGPDQLVELRMQDIVIPLEGAKYLVSACGYIDAELDKLYGAPPFYKVPDLGGLIGHLVVGLAPHTSVGVAARIIGYTETHVCFGTPNWHSAKRRDADGDADSIILLMDALLNFSRHYLSDRIGGLMDAPLLIQPLVLPHESQSQAHNIEVVKRLPPGFYEAAAARKKASEVGCVEIVKSRLETAGQFGGYHFTHGTSSLTTSRPRSAYSTLGSMLDKLDLQIRNANLIAAVDAAEIISNVISTHLVPDIMGNLRAYARQNFRCTACGKSYRRIPLAQRCSCGNGLIQTITRASVEKYLKLAKRLVNEYDVGAYQRGRIHALSDEIELVFGKGGGDQALLTDF

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)

Length

1109 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

122.895 kDa

Sequence

MSAEYFERLERGLREEMEIARRARSKGLDPETDVEIPIAVDLAERVEKLVSIPGVAERIREFEVQGLSREEAALAIGRDFAEGRLGKGASRLDAIDMAIRTSVALLTEGVVAAPIEGIARVGLGKNDDGSEYLKVYYAGPIRSAGGTAQALSVLVADYVRRSMGIAPYKPTDEEIERYVEEIGLYKRLQHLQYTPSDDEIRTIIRNCPVCIDGEPTEEEEVSGYRDLPRVETNRVRGGIALVSAEGIALKRPKIKKHVSKLGIDGWGWLDVLGGEKKDGGGSSGKFLRDLIAGRPVFSHPSRPGGFRLRYGRSRNTGLAAAGINPATMMVLNQFLAPGTQIKVEQPGKAAAVAPVSSIEGPTVRLTNGDVVRIDDPSSFPWISSPEALRRNISKIIDLGEILVSFGDFMENNRPLAPASYTFEWWAEEFRRAGGDPAGMEHVDGRTAIRLSRDFGVPLHPDHTYLWHDITLDELDLLADAASDGEIDGDALLMDMREDVKEVLEKLLVHHKVRDGMIVVEDALPLLLCLGVDETGRRWRREDLNADNALSAVNQLSGLVIRARAPTRIGCRMGRPEKSDRREMRPPPHVLFPTGSEGGKSRLVNEAAEHGFIEVVVERRRCPSCGKEGFAFRCECGAHTERVRACLSCGVRADDKCPRCGTETSAATRMRIDVKGTLARALESLGERVDNIRGVMGLTSRDSTPEPLEKGVLRAKHGVFIFKDGTSRYDLTDLPLTHFRPREIGTSVDALLDLGYTHDIHGKPLESDDQILELKVQDVVLCRNAGDWLLRVSKFIDDLLVKFYGLEPYYNAERPEDLIGRLMIGLAPHTSAGVLCRLIGFTRASAGYAHPYFHAAKRRNCDGDEDCVMLLMDALLNFSRSYLPEKRGGKMDAPLVLTTRINPAEVDKEAHNLDLSFIYPLEFYEATLRNANPKDVEGLIDLVSKRLGSEGQYCGFGFTHDTDDIAGGPRNSSYKTLETMIDKMKSQLELAKLIRAVDATDVAERVINSHFLPDLMGNLRAFSRQSVRCVKCNAKYRRPPLSESCPKCGGRLVLTVHEGSVRKYLEVSMKVAEEYGVSSYTRQRLELIQMEIESLFRSDKVKQTGLADFV

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

Length

1092 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

123.06 kDa

Sequence

MMDYFNELERETERLYEIARKARARGLDVSTTPEIPLAKDLAERVEGLVGPEGIARRIKELEGDRGREEVAFQIAAEIASQAVPDDDPEEREKLADQALRTALAILTEGVVAAPLEGIARVRIKENFDKSRYLAVYFAGPIRSAGGTAAALSVLIADYIRLAVGLDRYKPVEREIERYVEEVELYESEVTNLQYSPKPDEVRLAASKIPVEVTGEPTDKVEVSHRDLERVETNNIRGGALLAMVEGVIQKAPKVLKYAKQLKLEGWDWLEKFSKAPKKGEGEEKVVVKADSKYVEDIIGGRPVLAYPSEKGAFRLRYGRARNTGLAAMGVHPATMELLQFLAVGTQMKIERPGKGNCVVPVDTIDGPVVKLRNGDVIRIEDAETASRVRSEVEEILFLGDMLVAFGEFLRNNHVLMPAGWCEEWWIQTILSSPKYPGDDPLNLSYYRTRWNELEVSAGDAFRISEEYDVPLHPRYTYFYHDVTVRELNMLREWLNTSQLEDELVLELRPEKRILEILGVPHRVKDSRVVIGHDDAHALIKTLRKPLEDSSDTVEALNRVSPVRIMKKAPTYIGTRVGRPEKTKERKMRPAPHVLFPIGKYGGSRRNIPDAAKKGSITVEIGRATCPSCRVSSMQSICPSCGSRTVIGEPGKRNINLAALLKRAAENVSVRKLDEIKGVEGMISAEKFPEPLEKGILRAKNDVYTFKDATIRHDSTDLPLTHFTPREVGVSVERLRELGYTRDCYGDELEDEDQILELRVQDVVISEDCADYLVRVANFVDDLLERFYDLERFYNVKTREDLVGHLIAGLAPHTSAAVLGRIIGFTGASACYAHPYFHSAKRRNCDSDEDSVMLLLDALLNFSKSYLPSSRGGSMDAPLVLSTRIDPEEIDDESHNIDTMDMIPLEVYERSFDHPRPSEVLDVIDNVEKRLGKPEQYTGLMFSHNTSRIDEGPKVCLYKLLPTMKEKVESQITLAEKIRAVDQRSVVEGVLMSHFLPDMMGNIRAFSRQKVRCTKCNRKYRRIPLSGECRCGGNLVLTVSKGSVIKYLEISKELASRYPIDPYLMQRIEILEYGVNSLFESDRSKQSSLDVFL

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)

Length

1088 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

122.362 kDa

Sequence

MTILHSTMLSEVLDLESYRKKISDEVRECFDLASQARELGMDVTDKVEIPLASDMAERIEALIGISGIADQIRDLSKKMSREEVSLEMSRRVANIFKDNKKEALDKAIRVGLAILTEGILVAPLEGIADVYIGKNADGSDYVGISYAGPIRGAGGTAQALSVLIGDVVRRELGITRYIPTEEEIERYIEEIESYDRIKHLQYLPTPDEIKLVVKNSPVCIDGEGSEEEEVSGHRDMARVKTNRIRGGMCLVLCEGLVQKARKILKYTSSMHLEEWSFLSSISGKSDDKGSKKSDKFLKDIVAGRPVFSHPSRPGGFRLRYGRSRVSGLAAASLNPATMYIMGKFIAIGSQIKVELPGKAAAVTPCDTIDGPTVLLRNGDHVKINNIEKAKELYDEVVEITDAGEILIAYGDFLENNYNLPTASFTKEWWMQYLPDGLDGNEVDQFRAVELSRQYNIPLHPDFDYYWHDISFEELEYLISAVENGRLSDNSFLIPYSASEVLIKLGVQFKRSGNFLVLNQYYPLLVSLGYDVFEDKIKRVKPYQRKSSVLETVNYLSGITIKPRAPTRVGSRLGRPEKAGDRKMKPMVHSLFPVESYGEARRSILNANKKTDGTYKAEVFFYRCTSCGYESPSPTCPKCGSRSKPIGTKNSEIDLSVILRKAEDRLGIKLDELKEFKGVKKLMSKEKVAEPIEKGILRAIHGISVNKDGTCRFDMSDIPITHFRYKEIGISKEKLSELGYEVKDVNEIFPQDVIIPRKAAKYLFDVSKFIDDLLVRYYGLPPFYSLKSEEDLVGHLVIGLAPHTSGGVVGRIIGFSDVNAFYAHPFFHAAKRRNCDGDEDSVMLLMDGFLNFSARYLPSTTGGLMDAPLVLSVLINPDEIDKEALNVDTLQKYPLIFYEATERHAAPSELEETMMTMKVRIKKTATYRNSSYTFDTSDINKGVLVSSYKTLATMDDKISEQLGLARRIRAVDADDVAARVISTHFLPDMYGNFRRFFSQEFRCTKCNAKYRRIPLSGRCMKCGSDSLTLTIHKGSVIKYLDETLKIEKEYNIPKYLKERIDNLARTIKETFPDEEKPDAAIKITGLDMY

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

Length

1087 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

122.284 kDa

Sequence

MIMSQKPFDLEGYRKYITEKVREAFNVAQEARAKGLDVSDHVEIPLASDMAERIEALIGIKGIAQEIRDLSSRMSREEVSLEMSRRIAAMFKDNRKEALDKAIRVGLAILTEGILVAPLEGIADVYIGKNQDGSEYVGISYAGPIRGAGGTAQALSVLIGDVVRRELGISRFQPTEDEIERYIEEIESYDRIKHLQYMPTPDEIKLVVRNSPICIDGEGSEEEEVSGHRDMERIKTNRIRGGMCLVLCEGLVQKARKILKYTSSMHLDDWNFLANLGGKAEGKSSKKSDKFLKDIVAGRPVFSHPSRPGGFRLRYGRSRVSGLAAASLNPATMYIMGKFIAIGSQIKVELPGKAAAVTPCDTIDGPTVLLKNGDHVKINDIEKAREVYDDVVEITDAGEILIAYGDFLENNYPLPTPSFTVEWWEQYLPDGVNAKDIDQFSAVEISRKYGIPLHPYYDYYWHDISFEDLEFLVKNAEQWSITEDGMRVPYPAFDVFIRLGIEFRRSGDYLIIRDYYPLLISLGYDVRNGKIVNVKKYERKGSVMETVNYLSGLIIKPRAPTRVGSRLGRPEKAGDRKMKPMVHSLFPVESYGEARRSIIGANKNSEGSYKAEVFFYRCNSCGFETPTPVCPRCGGHCSPLGEKTGSIDLESILNRAESILGISLDSLKEFKGVKKLMSKEKVAEPIEKGILRAVHDISVNKDGTCRFDMSDIPITHFRYREIGIDERTLADLGYEVRDVNELFPQDVIIPRKAAKYLFNVSRFIDDLLVKYYNMPPFYSLESEEDLIGHLIIGLAPHTSGGVVGRIIGFSDVNAFYAHPFFHAAKRRNCDGDEDSVMLLMDGFLNFSARYLPSTRGGLMDAPLVLSVLINPDEIDKEALNVDTLSRYPVLFYEAAERHASPAEIEDTMMTMKVRIKKTGTYMGSSYTMDTSDINSGVLVSSYKTLGTMDEKINEQLGLAKKLRAVDADDVAARVISTHFLPDMYGNFRKFFSQEFRCTKCNAKYRRIPLSGRCQKCGSTSLTLTIHKGSVVKYLNETLKIAENYRLPDYLKARIDNLARTIKETFPDTEEEEKPEPREVKITGLDMY

Protein

DNA polymerase II large subunit: polC

Gene

polC

Protein

DNA polymerase II large subunit

Organism

Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)

Length

1080 amino acids

Function

Similarity

Belongs to the archaeal DNA polymerase II family.

Mass

121.576 kDa

Sequence

MIDHSLFDYNERLRKETYECYEIAKKARAMGLDVSDEVEIPIANDMAERVEELIHISGIAGEIRELSKSMSREELSLHISKKVASLLKDNRVEALDKAVRVGLAILTEGILVAPLEGIKDVKINKNDDGTEYVSIVYSGPIRSAGGTAQALSVLIADIVRRELNIGSFSPTDDEIERYIEEVEAYNRLKHLQYMPTPDEIRLVLKNSPVMIDGEGSEEEEVSGHRDMKRITTNRIRGGMCLVLCEGLIQKAKKVLKYTNVMHLNEWNILENIGKNKSDEKTENKSEKYLKDIIAGRPVFGYPNRPGGFRLRYGRSRVSGLAAASINPVTMKILNDFIAIGSQIKVELPGKAAAITPCDSIDGPMVLTRSGDHIKVKSIEQAEKIKNDIERITDLGEILIAYGDFLENNRNLDLSPFTREWWEYYLNDELSIYKSRDPDQFDAVNISRKYKMPMFPGYDYFWHDITMEELNLLINAIANGIINDDSMMLDASVSEILIKLGIEFKKHNNKLILHEYYPLIVSCGFDLINEKIVKVSDERKNDVLGTVNALSGIEIKPRAPVRVGARLGRPEKAGDRKMKPKVHGLFPLMNYGGSTRSIINAARSGSIMDIELGARICRACGTETPFVRCPKCGMPTEDSDSEKKFKIDISKALDDAALRVSTDIGTIKELKGVKKLMSRRSVIEPLEKAILRAKHGISINKDGTCRYDMSDIPITHFKYNEISLTRQRLMELGYSDSDINEIYPQDIIIPRDAASYLLNVSKFIDDLLVNYYGLGPYYMCNSEDDLIGHLVIGLAPHTSGGIVGRIIGFSDVNGCYAHPFFHAAKRRNCDGDEDSIMLLLDGLLNFSKKYLPSTTGGLMDAPLVLTLILDPEEIDKEALNVDTLQRYPLDFYIATEKNAPPASIENMMKTMKVLIKDGRYTGISYSFDTGDISYGTRLSAYKTIGSMEEKIEKQLGLARILRSVDENDVAARVLSSHFLPDIYGNFRSFFTQEFRCTKCNAKYRRVPLSGRCLRCGSSNIILTIHHGSIVKYLNETKKVMNEYKLPDYLVFRINRLLEQIESTFDIENGNDTTLDALIENE

Protein

DNA polymerase II large subunit: polC