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osgep

Gene
osgep
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Dictyostelium discoideum
Length
336 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Osgep likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
37.202 kDa
Sequence
MVYIMGFEGSANKLGIGIVKDDGTILSNIRHTFITPPGEGFLPKDTAKHHRSFILSLVEKSLEESKLKPSDIDCLAYTKGPGMGPPLRSVAVTVRMLSQLWDRPIVAVNHCIAHIEMGRLITGAVDPTILYVSGGNTQVISYSLKKYRIFGETIDIAVGNCLDRFARVIQIPNDPSPGYNIEQLAKKGKNLIELPYITKGMDVSFSGILSSIEGMVKNKQNKTQHSVEDLCYSLQEHLFSMLVETAERALAHCGQNEVLAVGGVGCNQRLQEMIQQMISQRNGKSFAIDERYCIDNGAMIAWAGYLIFKNGTTTPLSQTTTTQRFRTDQVDVTWRD

Gene
osgep
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Nematostella vectensis
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Osgep likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.988 kDa
Sequence
MPTVIGFEGSANKLGIGIIRDGVVLSNPRHTYITPPGQGFMPRDTAKHHQEHAIDILRRALDEAQIRPQDIDCICYTKGPGMGAPLVAVAVVARTVAQLWKKPIIGVNHCIGHIEMGRLITGANNPTVLYVSGGNTQVIAYLQKRYRIFGETIDIAVGNCLDRFARVLKLSNDPSPGYNIEQMAKKGKKLIELPYTVKGMDVSFSGILSYIECMAHKLLSSEECTPEDLCFSLQETVFAMLVETTERAMAHCGSNEVLIVGGVGCNKRLQEMMDVMAKERGAKLYATDERFCIDNGAMIAQAGWEMFQTGSVTPLEQTTCTQRFRTDEVEVTWRD

Gene
Osgep
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Rattus norvegicus
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.357 kDa
Sequence
MPAVLGFEGSANKIGVGVVRDGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALTEAGLTPKDIDCIAYTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPYTVKGMDVSFSGILSFIEDAAQRMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNVRLQEMMATMCQERGAQLFATDERFCIDNGAMIAQAGWEMFQAGHRTPLQDSGITQRYRTDEVEVTWRD

Gene
osgep
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Xenopus laevis
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Osgep likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.936 kDa
Sequence
MTIVVGFEGSANKIGVGIIQDGKVLSNPRRTYITPPGQGFMPSDTARHHRSCILDVLQEALEESNIKPEDVDCVAYTKGPGMGAPLLSVAIVARTVAQLWKKPLLGVNHCIGHIEMGRLITGAENPTVLYVSGGNTQVIAYSERCYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKKGKKFVELPYTVKGMDVSFSGILSYIEDMSHKMLSSGECTPEDLCFSLQETLFSMLVEITERAMAHCGSQEVLIVGGVGCNVRLQEMMGVMCEERGAKIFATDERFCIDNGAMIAQAGWEMFRAGQVTNLQDSWITQRYRTDEVEVTWRD

Gene
OSGEP
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Bos taurus
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.502 kDa
Sequence
MPAVLGFEGSANKIGVGVVRDGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTEAGLTSEDIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGATNPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPYTVKGMDVSFSGILSFIEDVAQRMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSQEALIVGGVGCNVRLQEMMETMCQERGARLFATDERFCIDNGAMIAQAGWEMFQAGHRTPLSESGITQRYRTDEVEVTWRD

Gene
osgep
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Danio rerio
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.728 kDa
Sequence
MTIVIGFEGSANKIGIGIIKDGEVLSNPRRTYITPPGQGFLPGETAKHHRSVILTVLQEALDEAGLKAADIDCVAYTKGPGMGAPLVTVAIVARTVAQLWGKPLLGVNHCIGHIEMGRLITNAQNPTVLYVSGGNTQVIAYSERRYRIFGETIDIAVGNCLDRFARVIKISNDPSPGYNIEQMAKKGNKYIELPYTVKGMDVSFSGILSYIEDAAHKMLSTDQCTPEDLCFSLQETVFAMLVEITERAMAHCGSQEVLIVGGVGCNLRLQEMMGVMCKERGARIFATDESFCIDNGAMIAQAGWEMFRSGHVTELPDSWITQRYRTDEVEVTWRD

Gene
OSGEP
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Homo sapiens
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.427 kDa
Sequence
MPAVLGFEGSANKIGVGVVRDGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTESGLTSQDIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGATSPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPYTVKGMDVSFSGILSFIEDVAHRMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSQEALIVGGVGCNVRLQEMMATMCQERGARLFATDERFCIDNGAMIAQAGWEMFRAGHRTPLSDSGVTQRYRTDEVEVTWRD

Gene
Osgep
Protein
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Organism
Mus musculus
Length
335 amino acids
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Similarity
Belongs to the KAE1 / TsaD family.
Mass
36.301 kDa
Sequence
MPAVLGFEGSANKIGVGVVRDGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALAEAGLTSKDIDCIAFTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPYTVKGMDVSFSGILSFIEDAAQRMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNLRLQEMMGTMCQERGAQLFATDERFCVDNGAMIAQAGWEMFQAGHRTPLKDSAITQRYRTDEVEVTWRD