nurA

DNA double-strand break repair nuclease NurA

451 amino acids

Involved in DNA double-strand break (DSB) repair (PubMed:18957200). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (PubMed:18957200). Exhibits 5' endonuclease activity and both 5' and 3' exonuclease activities (PubMed:22064858).

Belongs to the NurA family.

51.609 kDa

MRLLSKQSIERITKILLDELENVRENEQIRNIINSWKPLPSPEKSSIYAVDGSRSVSRLSGTVIYFLSALAVGSGKQLRLSYANAIKSNYGTSDQIVRMQMETLENMLGYLAYRKLEGEKRAILMDGTLTGSLVRPPVYPEDIRSLNVMRALIGESDFENLLNEFLEKLRDHYRKVEEHLEKNGNYDSPILTDNVVEKLRKKYIDTKVIAYGSGKVKVKIPRKALGYSPRVIPIEVLESSRGKSVDELLQELDEEKVELYLGKDDIYDALHMTLSYIEYLYSIDKLLEVKNLAYIAKSFYTKTLARTLGVEIVDTALLDAVIRTLIGHEKEGYLEIEHAVVPPKWSFPDFLLSKFRNIEKLIDKGIHLAYVRFEQGDVIYMLQSTTNIEKILPLILHHKAGGYLRPLQLAHHGVKISYKEARHTLEALINALRNRDPALKIFVKYGRSPLE

nurA

Probable DNA double-strand break repair nuclease NurA

389 amino acids

Involved in DNA double-strand break (DSB) repair (By similarity). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity).

Belongs to the NurA family.

45.314 kDa

MFFKIFVENTVILPNPLILTKIEGLLMIEYLLKNREQIIKKMEKINDINRKEVEEKWILDNFENPKDMGFAGGDGSCNKLDYISFSFYGVGAVSFIHGRGEKVKKAKEEYIFDITHPLDIEDRIRRYMLTLELKTALYVLKNYNIDYYIFDGSLFSLLIFTKKGIEMYERELEEIYNEYGKEFNKKIDEETKSGEIGIISKDLNLELNKKILVEHVEYILTLTKLINEFKDRIIGISKTSKINIYFDKNMPDIAIFTKYTDKSGYSEPIDFVNKLGDEKKEKHKQLSSVVKGINFIKNKPFYAKIDTAYIQFVRLEDNCGVVGLTSFNKIDKEVLSSLKEISINGYPYILKKSHETVEITTKKLEAIAKLLNIDDPIARHILGKKKKKF

nurA

DNA double-strand break repair nuclease NurA

339 amino acids

Involved in DNA double-strand break (DSB) repair (PubMed:22135300). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Processes linear dsDNA probes with 3' or 5' single-stranded overhangs or blunt ends (PubMed:22135300).

Belongs to the NurA family.

39.125 kDa

MIRKIYDKLVESHNEIKNQIYNIANYLKQEIQDKVNEYWNEYVINHEQSETCKFVAIDGGSFGRPMRIGIVYAVGAESVIGDNKGVKTLSEDGQIGIFKPGNDAQERISLLMEALELSLALRDGSKGDYILMDGSLSKKIGNKVDIQQFSDEELKLIRNVDLNGIISIKDERKMRDLLMLLNQFLVSKIIEEYDGNVLWISKVSRGRDLFGTDYPDITVLELFTEKRGFSKLIIKNIDIEKISEIPEIEVLRKMEYTTFYTRLDNGKRVIRVDIVGRVDEKIVKEIMDRLSGVSIKGYPFPLLKAHMDVRFSAMDREKIIKLVGSKLHKDIEWWPSQFY

nurA

DNA double-strand break repair nuclease NurA

332 amino acids

Involved in DNA double-strand break (DSB) repair (PubMed:12052775). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Exhibits both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double-stranded DNA (PubMed:12052775).

Belongs to the NurA family.

38.888 kDa

MIDKAYEELIKMKEKIMRDSYTIHKELSESVESILNELWINYSPESVEHSKKLLAIDGGMWVKETRQGVIFIVNAKAIVFEGINEINSEGKVLVHIFSPGNYAKERIELLMQLLELQLALKLVENVDYVLLDGSFSKKLGRHKSELKVDLLDDIVSIDKILSLEEKDEDNMLRFLIAENQLVLSELVSRYKDKLLFISKNSKSSDLFKQAYSDITILELFTQNCGYSKILEKKIDENYILSRKASKLLSGLNYYFTNLRLEPSERLFRLDFFNADKIFEYLKVLKPVSLKGYPYPLIKVHKDVRVGKEDRERIYSILEMKRKDISWWPSQFY

nurA

DNA double-strand break repair nuclease NurA

331 amino acids

Involved in DNA double-strand break (DSB) repair (By similarity). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity). Exhibits both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double-stranded DNA (PubMed:18194801).

Belongs to the NurA family.

38.016 kDa

MIKDVYELLLSRKNEIEKQISLLDETSNNLLKEKIKEKWKEYCQTQGKLSTVLAIDGGMWIKELRSGIVYIVNAEIVKAEGFNVTPIDSKALIGVLRPGNMAKERVSLLMQLLELKLGLKHGDKAEYILFDGSIVKKIGKHKFSTKISLLDDIDVMDDKIYSLEENDEELMHKYLVAENQLVMSALISKYKGKLVWISKNSKSTELFQENISDVSLLELFTKNCGYTIGIEKKISSENIISPKASTILSNASFYSFYTRLKEGEKILKIEMFNNEIENIISILSPISIKGYPYPLLKVHTDVKVSRQDRERIKQLLNIKKKDIEWWPSQLF