Protein
DNA mismatch repair protein MutL
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Function
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker, a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
Similarity
Belongs to the DNA mismatch repair MutL/HexB family.
Sequence
MPTPIHVLPPHVARLIAAGEVVSRPLDVVRELVENALDAGASRIEIEVDGGGLERVQVRDNGSGIAAQSVPLAPARHATSKLTAGPETGSLSVTTLGFRGEALWAAAQAGELELTTRPAAQVGAARLRAQGDAVEVSRTSAPAGTTVTVSQLFARLPARLRTQASAAAEVRDITALLGRYVLHHSALHWRLTVDGDPRLTHAPADHRGAVATVYGPLSANRVLTLDTPGVRGVVSRPELTRARRDRMHFAVNGRPIVAPPELERAVIDAYAELLPAGTAPLCVLDLTVAPEDYDPNIHPAKQVVALADLPAVALRVRDAVAGALAGHPLVRAAPALIAPPEPHPAPTAGNFPDLTLLGVYQELYLLAQGEGDLWVVDAHAAHERALYERLGRELGTAAPLELPTPELLHLTPEQTARLHERGAELRGWGLTIEDFGAGLARLRTLPAALAALPVPRLHEVVVETALSGGPDPRREVLARLACLPALKAGMLDAERGALVLAALRECEQPWACPHGRPTVLRLSERDLAHAFGRRGVRDVARGRDSVV