Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
Similarity
Belongs to the ATP-dependent DNA ligase family.
Sequence
MNTNRRSRSPDEEALEEDQHQYGAGTLSLEELDEHFPNRPRNHSKTFPFSDLFRTLFNPLIDCKPSTSGGTVRGPKPGRGGHFSKVSYHEQRRHIIERFMSRWRSEVGNDFYPAMRLILPDKDRDRGVYGLKENTIGKLLVKVMKIDRNSEDGYNLMHWKLPGGQSGVSRSVGDFAGRCLEVVSKRAMRAQPGDLTIADVNVLLDRLAAASGEAEQLPIFEEFYRQMNAEEMMWLVRIILKDMRVGATERTFLNLWHPDAEALFSVSSSLRRVCWELFDPEFRLEQQETGIKLMQCFQPQLAQFQMTTTWEKLVKNLGVTEENPEFWIEEKLDGERMQMHMIEDDTVPGGFRFAFWSRKAKDYTYLYGESLGDEQSALTRHLHKAFDDGVRNLILDGEMITWDIDIDKMVPFGTLKTAALEQQKNPSKAGPRPLYRVFDILLLNDKPLTEYTLNDRRRALERAVVGVHRRLEILPFERATSPDAIEPLLRRVVAEASEGLVLKNPRSRYSLNSRNNDWIKVKPEYMSDFGESLDCVVVGGYFGSGRRGGTLSSFLCGVRVSQNFIKSGNASAEKCLSFVKVGGGFKAEDYAEIRHHTEGKWQDWDPSSPPTEYIELGGGEKLQYEKPDVWIRPSDSVVISVKAASITQSDQFAMGWTLRFPRFRKLRLDRAWDSALDMDEFEVLRSKIKDQEQERKKMEMENRKRKPATKRARKDLVIAGMSDPSSSSAATPVIAPKETREASKRLFEGLDFCVLSDSLKPNKMTKPALEKLIKDHGGRIHQQVMDHSGQGKIIIPIADKNVIKVASLRKANPEMDIIRPKWIFDCLVQPMPFTKQKENKKGYLLPFEPTHLFHSGSEETSEEAEQAVDKFGDSYAGDLADINELKAIMEGMESDDYVSDSDWDSDSGRGRGGGDGFDMNHFLDHLEEQGTSLDDLRSFMFRRCRVFFALPSAGNGDGAAESKALRLKNYIRFGNGKVVDELETATHVVVVTAPLGESSKKEEREIAAELRYKISLREMGSPMPRIVKGEWVEDSWKEGTVVDEEEYVAG