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mosmob

Gene
mosmob
Protein
Modulator of smoothened protein
Organism
Danio rerio
Length
167 amino acids
Function
Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation.
Mass
18.192 kDa
Sequence
MDKLTIISGCLFLAADIFAIASIANPDWINTGGQEGALTVGLVKQCQTIHGRNRICVSPSLPPEWVTTLFFIILGIVSLTITCGLLVISHWRREATKYARWIAFMGMVLFCMAALIFPVGFYINQVGGQPYKLPNNTVVGSSYVLFVLSIFFTIVGLLFAGKVCLPG