Description
Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation.
Sequence
MDKLTIISGCLFLAADIFAIASIANPDWINTGGQEGALTVGLVKQCQTIHGRNRICVSPSLPPEWVTTLFFIILGIVSLTITCGLLVISHWRREATKYARWIAFMGMVLFCMAALIFPVGFYINQVGGQPYKLPNNTVVGSSYVLFVLSIFFTIVGLLFAGKVCLPG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service