Protein
Monoterpene epsilon-lactone hydrolase
Organism
Rhodococcus erythropolis
Function
Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone derivatives of dihydrocarvone (4R)-4-isopropenyl-7-methyl-2-oxo-oxepanone and (6R)-6-isopropenyl-3-methyl-2-oxo-oxepanone, and ethyl caproate.
Similarity
Belongs to the 'GDXG' lipolytic enzyme family.
Sequence
MSATDTARAKELLASLVSMPDATIDDFRALYEQVCATFELPDDAQVEPVDANGADALWVSAPGVSADTVAVVVHGGGFTMGSAHGYRELGYRLSKSGNLRALVVDYRLAPESPFPAPVDDVVAAYRYARSLDGVENVFLVGDSAGGGIAMSALITLRDAGEQLPDAAVVLSPLVDLAGESPSLVDRAHLDPLPAAVLVNGMGGLYLNGLDVRHPVASPMHGDLTGLPATLVLVGTDEGLHDDSTRLVDKLKAADVEVQLEIGEGLPHIWPIFSFHPDAVAATDRIGEFLRSHVAAPR