About Products Protein Database Contact

mab-5

Gene
mab-5
Protein
Homeobox protein mab-5
Organism
Caenorhabditis elegans
Length
200 amino acids
Function
Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration (PubMed:8898225, PubMed:23784779). During postembryonic development, required for posterior-specific pattern formation (PubMed:2903796). Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation (PubMed:2903796, PubMed:21307099).
Similarity
Belongs to the Antp homeobox family.
Mass
22.399 kDa
Sequence
MSMYPGWTGDDSYWAGAGTTASSQSASSGTSASASSSAAAAAAANNLKTYELYNHTYMNNMKHMLAAGWMDNSSNPFAYNPLQATSANFGETRTSMPAISQPVFPWMKMGGAKGGESKRTRQTYSRSQTLELEKEFHYHKYLTRKRRQEISETLHLTERQVKIWFQNRRMKHKKEAKGEGGSNESDEESNQDEQNEQHSS

Gene
mab-5
Protein
Homeobox protein mab-5
Organism
Caenorhabditis elegans
Length
200 amino acids
Function
Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration (PubMed:8898225, PubMed:23784779). During postembryonic development, required for posterior-specific pattern formation (PubMed:2903796). Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation (PubMed:2903796, PubMed:21307099).
Similarity
Belongs to the Antp homeobox family.
Mass
22.399 kDa
Sequence
MSMYPGWTGDDSYWAGAGTTASSQSASSGTSASASSSAAAAAAANNLKTYELYNHTYMNNMKHMLAAGWMDNSSNPFAYNPLQATSANFGETRTSMPAISQPVFPWMKMGGAKGGESKRTRQTYSRSQTLELEKEFHYHKYLTRKRRQEISETLHLTERQVKIWFQNRRMKHKKEAKGEGGSNESDEESNQDEQNEQHSS