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kynU

Gene
KYNU
Protein
Kynureninase
Organism
Homo sapiens
Length
465 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Similarity
Belongs to the kynureninase family.
Mass
52.352 kDa
Sequence
MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN
Protein
Kynureninase: KYNU

Gene
kynu
Protein
Kynureninase
Organism
Nematostella vectensis
Length
465 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
52.709 kDa
Sequence
MAYKPTQTLRKLAEKSSLDIVSREFADYMDSKDPLRKMRDEFFYPRVKDLPGVDLSLVDGDQDSIYFCGNSLGLQPRGCRELIDRSLTKWEQMGVLGHTSGWCPWKPIEDILIKPMAEIIGAKDIEVVAMNTLTVNLHMMMVPFYRPTPQRYKILMEGKAFPSDQYAAQSQVHFHGFDPDKDIIEVFPREGEQSLRTEDILSAIEEHGNSITLVLFSGVQYYTGQFFDMKTITAAAQKKGCVVGWDLAHAVGNVELHLHDWNVDFACWCTYKYLNSGPGGIAGAFVHEKHAYNFELPKFAGWWGTDRNSRFQMRKEFEQIPGAHGYQCSNPPVFQCLLLRASLDVFEKTSVKEIRAKGDLLTAYLELLLLHYFSPSNDITKNGNTPHVSIITPADPKDRGCQLSVKFSVPVDKVFEELCKRGFVGDIRHPDVMRIAPAPLYNSFADVHRFISMLNAAFKTITPNS
Protein
Kynureninase: kynu

Gene
Kynu
Protein
Kynureninase
Organism
Mus musculus
Length
464 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Similarity
Belongs to the kynureninase family.
Mass
52.325 kDa
Sequence
MEPSPLELPVDAVRRIAAELNCDPTDERVALRLDEEDKLSHFRNCFYIPKMRDLPSIDLSLVSEDDDAIYFLGNSLGLQPKMVRTYLEEELDKWAKMGAYGHDVGKRPWIVGDESIVSLMKDIVGAHEKEIALMNALTINLHLLLLSFFKPTPKRHKILLEAKAFPSDHYAIESQIQLHGLDVEKSMRMVKPREGEETLRMEDILEVIEEEGDSIAVILFSGLHFYTGQLFNIPAITKAGHAKGCFVGFDLAHAVGNVELRLHDWGVDFACWCSYKYLNSGAGGLAGAFVHEKHAHTVKPALVGWFGHDLSTRFNMDNKLQLIPGANGFRISNPPILLVCSLHASLEVFQQATMTALRRKSILLTGYLEYMLKHYHSKDNTENKGPIVNIITPSRAEERGCQLTLTFSIPKKSVFKELEKRGVVCDKREPDGIRVAPVPLYNSFHDVYKFIRLLTSILDSSERS
Protein
Kynureninase: Kynu

Gene
Kynu
Protein
Kynureninase
Organism
Rattus norvegicus
Length
464 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Similarity
Belongs to the kynureninase family.
Mass
52.47 kDa
Sequence
MEPSPLELPVDAVRRIATELNCDPTDERVALRLDEEDKLKRFKDCFYIPKMRDLPSIDLSLVNEDDNAIYFLGNSLGLQPKMVKTYLEEELDKWAKIGAYGHEVGKRPWIIGDESIVSLMKDIVGAHEKEIALMNALTVNLHLLLLSFFKPTPKRHKILLEAKAFPSDHYAIESQIQLHGLDVEKSMRMIKPREGEETLRMEDILEVIEKEGDSIAVVLFSGLHFYTGQLFNIPAITQAGHAKGCFVGFDLAHAVGNVELHLHDWDVDFACWCSYKYLNSGAGGLAGAFIHEKHAHTIKPALVGWFGHELSTRFNMDNKLQLIPGVNGFRISNPPILLVCSLHASLEIFQQATMTALRRKSILLTGYLEYLLKHYHGGNDTENKRPVVNIITPSRAEERGCQLTLTFSISKKGVFKELEKRGVVCDKREPEGIRVAPVPLYNSFHDVYKFIRLLTAILDSTERN
Protein
Kynureninase: Kynu

Gene
kynu
Protein
Kynureninase
Organism
Monosiga brevicollis
Length
460 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
51.259 kDa
Sequence
MHLARELGVNLADQRLAQALDEADPLAHLRQEFSIPQMKDIKQADLKLVEAESDCIYLCGNSLGLMPKRTRTIVNEELDTWATGGVTGHFPDGPGKRPWVSIDETVTDKCARVVGALPEEVAIMNTLTVNLHLLMVSLAHTMARQVPFYRPTSDRFKILVEAKAFPSDHFAVLSQLRMHGHDESALIEVKPREGEHNIREEDLLAILEEQGDSIATVLVGGVHYYTGQFFDLQRLCAAAHNKGCTFGVDLAHAVGNVPLQLHDWDIDFACWCTYKYLNSGPGGIAGAFIHKKHEGTSRPYLQGWWGVQLNERFRMDHDASFMPGVRGLQLSNPGVLQTVALLGSLEIYEQTDMASLRAKSLKLTAYLEQLMQALVNEEGHAPRFEIITPTDPERRGCQLSILFKVDIDAAFEALEKRGVVCDVRRPDVMRIAPVPLYNTFTDVYRFVTTLRDALNASASS
Protein
Kynureninase: kynu

Gene
kynu
Protein
Kynureninase
Organism
Dictyostelium discoideum
Length
451 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
50.799 kDa
Sequence
MDKFFEYIKNQNLSLEDEKLADKLDQLDQLSSIKEEFYFPITKDIATDLSRVKDEDLDKPVIYLTGNSLGLQPKEIEKQLVCNYLNDWRKYGVEGHHKGDHPFIHIDEEIQASLSKIVGALPSEVCPMNSLSTNIHVLLSNFYKPTQTRHKIIIEYGAFPSDLYVTESQIRHNSFNPETSLIKIKPRDGEYTLRTDDIINVLKEHGDSVAVVMLSGIQYFTGQFFDMKKITEVGHEIGAIVGWDLAHAAGNVELSLHDWNVDFACWCTYKYLNSGPGCIAGIFVHSKHTESFNLSTDSRLLGWFGNKLSNRFQKEKEFVAEDGALGFRMSNPSVADCTALRASLSVFEKAGGIKKLAEKSTIITGYLEYLLTHKLKTTDVQIITPSEANQRGSQLSLLIKGIKASQLKVNLSNSGIVCDVRDPDVIRVAPAPLYTSFNDVKYFIQKLNENM
Protein
Kynureninase: kynu

Gene
kynU
Protein
Kynureninase
Organism
Shewanella woodyi (strain ATCC 51908 / MS32)
Length
430 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.545 kDa
Sequence
MIFENTLAFAQQQDRNDPLAHYSDQFHHPVIDGKEVLYFTGNSLGLQPKTAKEHINQELEDWAKWGVEGHFHAVNPWVSYHEILTPASAELVGANESEVVCMNSLTTNLHLLFVSFYKPTAKRFKIISEAKMFPSDRYLLETQVRHHGLDPDDAIIEISPREGEYLIREEDIIAAVNDNADELALLFFGGVNYFTGQLFDMQRLTKAAHGVGALAGFDLAHAVGNVPMHLHDWDVDFAAWCTYKYLNSSAGNVGGIFVNDRHGNNTKINRFGGWWGHNKERRFLMENSFEPMTGAEGWQISNAPVMGMAILKSSLDIFHEAGIENLRAKSLKLTAYLEFVFNDIVNQFTDIKLEIITPTDPTQRGCQLSIKLVGTNKEFFEALTKAGVIADFREPDVIRLAPTPLYNSFEDVYLLGQTLKVLAQNWRQHG
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Length
429 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.976 kDa
Sequence
MREEELIQEEKAANRLDTADPGHRHLFHVPPADGGRYQQAAYLAGNSLGLQPRATRDELFADLEAWRRLGVEGHLAADRPWLPYHELLTAPTARLVGARPAEVVVMNSLTVNLHLLMVSFYRPTGVRTRIVIEDSAFPSDSYAVRSQARFHGLDPDSTVVRLAPRPGEDTLRTADVRDLLAAEGDTIALVLLGGVNYLTGELMEIPEITAAGRAAGAVVGWDLAHAAGNVPLALHDWDVDFAAWCSYKYLNSGPGGLSGVFVHERHLADPTLPRFEGWWSTEAATRFEMSPVARPPATAEAWQVSNPPILAMGPVRTSLEVFDSVGMTALRERSVRLTGYLEWLLDQVTPGRPLAVVTPRDPDRRGAQLSVRIGTGSAAELAKRLRLEHGVVADAREPDVVRFAPVPLYSTYHDCWRVADALAATVEVH
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.333 kDa
Sequence
MNSTALEPTLEFARKLDQEDPLRHFRDEFYLPPNSIYMDGNSLGLLSKRAEKTLFTILQDWKLLGIDGWTKGTYPWFDLSEKIGAMLAPLVGASPEEVIATGSTTVNLHQLVSTFYQPEGKRTKILADELTFPSDIYALQSQLRIHGYDPSTHLIRVKSRDGRFLEEEDIIAAMSEDVALVVLPTVLYRSGQILDIQLLTDEAHKRGILIGFDACHSIGAIPHSFSEWGVDFAFWCNYKYMNGGPGCVAGLYVHRKHFGSAPGLAGWFGSKKDKQFDMEHTFTPSLTAGAYQIGTPHLLSLAPLIGSLEIFQEAGIERIRQKSLQLTNYFMYLIEQELSHFGFIIGNPKDDVRRGGHISLEHEEAARICKSLKENGVIPDFRAPNIIRLAPIALYTSYEEVWNVVQIMKKIMQEKQYKKFSNEREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.542 kDa
Sequence
MYTEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIHAMTDDIALILLPSVLYRSGQVLDMKRLTAEAHKRGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHCNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKEAGIERLREKSLHITSYMLNLIAHELSDFEFTIGNPLEDEKRGGHIYLEHAEAARICKALKADGVIPDFRAPNGVRLAPVALYNTYEEVWKSVQILKKIMKDEEYKQFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.442 kDa
Sequence
MDQNPFEASYEYAIQSDKQDELAAFQNEFYKKADTIYLDGNSLGLLSKRAEKSLLTMLNSWKEHGIDGWTEGEYPWFFLSEQLSEHIAPLIGALSEEIIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPNEHLVRVKSRDGRTLDEEDIIAAMTDDIALILLPAVLYRSGQILDMKRLTAEAHKRGIHIGFDLCHSIGAIPHQFQEWGVDFAVWCNYKYLNAGPGSVGGLYVNKKHFARLPGLSGWFSSRKDKQFDMEHTLTAAEHAGAYQIGTPHIFSIAPLIGSLEIFKEAGIDRLRQKSLHITRYMLHLIDYELTDKGFTIGNPLEDEKRGGHIYLEHPEAARICKALKANGVIPDFRAPNGIRLAPVALYNTYEEVWKSVRILKKIMTNEEYKQFENKRGVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.754 kDa
Sequence
MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGKLTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPEEHLVRVKSRDGRTLSEEDIIHAMEDDIALILLPSVLYRSGQILDMKRLTTEAHKRGIHIGFDLCHSIGSIPHHFKDWDVDFAVWCNYKYLNAGPGSVAGLYVNSKHFNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKDAGIERLREKSLHITRYMLNLIGHELKDFEFTIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWKSVQILKKIMKNEEYKQFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus cereus (strain ZK / E33L)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.707 kDa
Sequence
MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIQAMTDDIALILLPSVLYRSGQILDMKRLTAEAHKRGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHFNRPPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKDAGIERLREKSLHITRYMLNLIDHELKDFGFTIGNPFEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWQSVMILKKIMKDEEYKQFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.659 kDa
Sequence
MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEESIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIQAMTDDIALILLPSVLYRSGQILDMKRLTAEAHERGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHFNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHILSTAPLIGSLEIFKDAGIERLREKSLHITRYMLNLIDHELKDFGFAIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWQSVMILKKIMKDEEYKQFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.7 kDa
Sequence
MYKEPFQPTYEYALECDKHDELKDFQSEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEFGIDGWTEGEHPWFFLSEKLGELTAPLIGSLPEETIVTSSTTANIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIHAMTDDIALILLPSVLYRSGQILDMKRLTAEAHKRGIHIGFDLCHSIGSIPHHFKEWDVDFAVWCNYKYLNAGPGGVAGLYVNNKHFNRLPGLSGWFSSRKDKQFDMEHSLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKEAGIEKLREKSLHITRYMLDLIEHELKGFEFTIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWNYVQILKKIMKNEEYKNFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus thuringiensis (strain Al Hakam)
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.636 kDa
Sequence
MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLFTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIHAMTDDVALILLPSVLYRSGQILDMKRLTAEAHKRGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHFNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKEAGIERLREKSLHITRFMLNLIAHELSDFGFTIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWHSVQILKKIMKDEEYKQFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus anthracis
Length
428 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.602 kDa
Sequence
MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIQAMTDDIALILLPSVLYRSGQILDMKRLTAEAHERGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHFNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKEAGIERLREKSLHITRFMLNLIAHELSDFGFTIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWQSVMILKKIMKDEEYKQFENKREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Bacillus clausii (strain KSM-K16)
Length
427 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.667 kDa
Sequence
MPCFDSVYTKEYAQQLDAVDPLARFRNEFYIDEDSIYLDGNSLGLLSTRAEQSLLDVLDSWKQYGIDGWTKGKHPWFYLSESLGEKMASLVGAKAEEVIVTGSTTTNLHQLVSSFFRPEGKKTKILADELNFPSDIYALKSQLHLQGFDPEEHLIQVKSDNGHLLNEEDIIAEMKEDIALIVLPSVLYRSGQILDMERLTTAAHQRNILIGFDLCHSIGAIPHQLRKWDVDFAFWCTYKHVNGGPGSVAALFVNEKHFGRRPGLAGWFSSNKQKQFDMEHTLTPAEHAGAFQIGTPHIFSIAPLIGSLAIFAEAGIEQIRKKSLKLTDYMMTLIEHELSDYQFTIQNPRDERRGAHLYIEHDEAARICKALKEENVIPDFRSPKGIRLAPVALYNTFKEVWNTIQVLKFIMKEERYKKFKNERDVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Myxococcus xanthus (strain DK 1622)
Length
426 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
47.76 kDa
Sequence
MTTPYLFEDSESFARKLDAEDALRGYRDAFHFPPGPDGKPVVYLAGNSLGLQPRNAARYIQEELEDWARLGVEGHHHGRHPWLHYHELVTEHAARLVGAKPLEVVVMNTLSVNLHLMMVSFYRPTKQRFKILVEAGAFPSDQYAVASQVRFHGYDAREAVLELKPREGEETLRTEDILETIERHGHEVALVMLGSVNYLTGQAFDLAAITKAAHAKGCFVGFDLAHGAGNLRLSLHDDGPDFAVWCSYKYLNAGPGALGGVFVHERHAHTKDLPRFEGWWGHDKQTRFQMGPTFSALPGAEGWQLSNPPIFQLAALRASLELFDQAGMAALRAKSERLTGYLEFLLDRLPEGFVRITTPRDVKQRGAQLSLRFRGEPQGLLKRLGDAGIICDFRKPDIIRAAPAPLYNSFTDVYRFVKTLEGHARE
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)
Length
425 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
47.194 kDa
Sequence
MTLTAPRKHAIEQDQQDALAPYRNEFYLQEGSIYMDGNSLGLLSKRAEATLLESLADWRELGIDGWMKGRHPWFDLSEKLAALNAPLVGGRADEVMVTGSTTVNLHQLVATFFAPSGRRTKILADSLTFPSDIYALQSQLRLRGLDPAEHLVQVESRDGRFLDEADIIAAMTDDIALIVLPTVLYRSGQILDMERLTREAHARGILIGFDGCHSVGAIPHAFHDWGVDFAYWCNYKHLNGGPGTVGGLFVHERHFGTLPGLTGWFGSRKDKQFDMNHTMTPAENAAAFQIGTPHVLSLAPQIGALELFAEVGIDAVRAKSLALTDYMMTLVDQELTAYGFVIGNPRDAKRRGAHLSLEHPEAARICKALKAHQVIPDFRAPNIVRLAPVALYNSFEDVYEVVSILKTIMDEKQYEQFKNEREVVA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101)
Length
425 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
48.72 kDa
Sequence
MTFQNTREFAKQLDAQDALNHYQEQFIFPKVNDKRVIYFTGNSLGLQPKRTKAYIDEVMNDWAELAVEGHFYAEKPWWDYQERFSEPLSKIVGALPSEVTVMNTLTVNLHLLMVSFYQPKGKRYKIICEEKAFPSDQYMFQSQVHFHGYKPEDAIVEIKRREGEHNIRLEDVLAKIEEVGDELALVLIGGVNYYTGQVFDIKTITAAGQKAGAKVGWDLAHAAGNIKLELHDWNVDFAAWCSYKYMNSGPGNASGVFVHERHHNDPDLPRFAGWWGHNKERRFKMEPNFDPVHGAGGWQISNLPVLSLAPYLASVEMFAEVGMDALIAKRDHITSYLEFILHEIDKEVESTFEIITPSNPEERASQLSVFLHGEGRSLFDYLMKNGVITDWREPNVIRLAPVPLYCSYEDMYDFGQILKKGILGK
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Length
425 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
49.035 kDa
Sequence
MIFQNTLEFAQQLDNQDELKEYKNEFIFPQHEGKNVIYFTGNSLGLQPKSARNYVDEVMNDWANLAVEGHFYADKPWWDYQERFANPLSKIVGAKPLEVTVMNTLTVNLHLLMVSFYRPTKKRYKIICEEKAFPSDQYMFQSQVNFHGYKPEDAIVEIKRREGEHNIRLEDILSKIEAVGDELALVLFGGVNYYTGQVFDMKTITEAGHKQGAKVGFDLAHAAGNIKLELHDWNVDFAAWCSYKYMNSGPGNASGCFVHEKHHSDSNLPRFAGWWGHNKERRFKMEPTFDPVHGADGWQISNLPILSLAPYLASVEMFAEVGIEKLIRKRNQITAYLEFILHEIDKEVKGHFEILTPTNQEERACQLSVFLHGEGRSLFDYLMKNGVVTDWREPNVIRLAPVPLYCSFEDMYNFGQILKKGILEN
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Gramella forsetii (strain KT0803)
Length
425 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
49.068 kDa
Sequence
MQFENTREFAKKLDNEDKISKYRDEFIFPKVNGKDVIYFVGNSLGLQPKTARKYVDEVMKDWAELAVEGHFYAEKSWWDYHERFSEKLARVVGANPSEVTVMNTLTVNLHLLMVSFYRPSGKRYKIICEEKAFPSDQYMISSQVRFHGYEPSDAIVEIMKREGENNFRTEDILKKIEEVGEECALVLIGGVNYYTGQVFDMETITKAGHDIGAFVGWDLAHGAGNIELKLSEWNVDFAAWCSYKYMNSGPGNASGCFINKKYHNKKDIPRFEGWWGHNKERRFLMEPEFQPEPTADAWQISNAPILALAPYLASLEMFDEVGMPALIEKRNKIVAYLEFVLHEIDEEVDSSFEIITPADQNERGTQLSVFLHGEGKELFRYLMDQGVITDWREPNVIRLAPAPFYCSFEDMYEFGQILKKGILSK
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Koribacter versatilis (strain Ellin345)
Length
424 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
47.776 kDa
Sequence
MAAAAFDTTENFAIEMDARDPMSRFRGRFHIPPAPDGSASVYLVGHSLGLQPKTVRAYLEQELKDWETLGVEGHFRGKHPWMPYHRLLTEQTARLVCAQPSEVVVMNSLTVNLHLMMVSFYRPTRERHNILIEGSAFPSDQYAVQSQIKFHGFDPASSLLELCPRVGEATMRDEDILELIEREGQSIALILLGGVNYATGQAFDMAEITKAGHAQGCVVAFDCAHAAGNLELKLHEWDVDWAAWCSYKYLNGGPGCIGGCFVHERYARDFELPRFAGWWGHDQETRFKMGPEFHPMAGAEGWQLSNPSILTMAALRASMEIFDEAGIGKLRQRSIALTGYLEFLLDQQKSARFEIITPREPERRGAQLSIRVAAGNRSVCDRLVEEGALCDWREPDILRVAPVPLYCSYRDCYRFVQRFVANLN
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Stenotrophomonas maltophilia (strain K279a)
Length
424 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.8 kDa
Sequence
MSDLLSRTHAIALDAADPLRPLRNEFLIPRHGGGEQTYFVGNSLGLQPRGAQAAVQEVMKQWGELAVEGHFTGPTQWLSYHRLVSAQLARVVGALPSEVVAMNTLSVNLHLMMVSFYRPTAQRPVILMEAGAFPTDRHAVEAQIRFHGFDPAECLVEVQPDEANGTISLTAIERAIAEHGPRLALVLWPGVQYRTGQAFDLDAITRAARLQGARIGFDLAHSVGNLPLRLHDVAPDFAVWCHYKYLNSGPGAVAGAFVHERHHRDTTLPRFAGWWGHEEATRFQMAPQFTPAIGAEGWQLSNPPILGLAPLRASLDLFERAGMEALRSKSLALTGMLEALVRARLSGVLDIITPAEPQRRGCQLSLRVIGGRERGRALFEHLRGIGVLGDWREPDVIRISPTPLYNRYLDVHHFVEEVEAWAGL
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
424 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.2 kDa
Sequence
MMTDPLSRSHAAALDAADPLRALRDAFVFPQHGGQDQTYFVGNSLGLQPRQARAMVSEVLDQWGALAVEGHFTGPTQWLTYHQLVRDGLARVVGAQPDEVVAMNTLTVNLHLMMASFYRPSAERAAILIEAGAFPSDRHAVESQLRLHGLDPDTHLIEVEPDAADGTLSMDAIAATIAQHGPRLALVLWPGIQYRTGQAFALGEIARLARAQGAAVGFDLAHAVGNIPLSLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHAHSNLPRMAGWWGHEQPTRFRMEPQFVPSPGAEGWQLSNPPVLALAPLRASLELFDQAGMPALRAKSEQLTGHLEQLIHTRVPQVLQIVTPADPAQRGCQLSLRVAGGRTQGRALFEYLQSVGVLGDWREPDVIRIAPVPLYNRFCDLHQLVEHVETWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas campestris pv. campestris (strain B100)
Length
424 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.17 kDa
Sequence
MMTDPLSRSHAAALDAADPLRALRDAFVFPQHGGQDQTYFVGNSLGLQPRQARAMVSEVLDQWGALAVEGHFTGPTQWLTYHQLVRDGLARVVGAQPDEVVAMNTLTVNLHLMMASFYRPSAERAAILIEAGAFPSDRHAVESQLRLHGLDPDTHLIEVEPDAADGTLSMDAIAAAIAQHGPRLALVLWPGIQYRTGQAFALGEIARLARAQGAAVGFDLAHAVGNIPLSLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHAHSNLPRMAGWWGHEQPTRFRMEPQFVPSPGAEGWQLSNPPVLALAPLRASLELFDQAGMPALRAKSEQLTGHLEQLIHTRVPQVLQIVTPADPAQRGCQLSLRVAGGRTQGRALFEYLQSVGVLGDWREPDVIRIAPVPLYNRFCDLHQLVEHVETWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
424 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.2 kDa
Sequence
MMTDPLSRSHAAALDAADPLRALRDAFVFPQHGGQDQTYFVGNSLGLQPRQARAMVSEVLDQWGALAVEGHFTGPTQWLTYHQLVRDGLARVVGAQPDEVVAMNTLTVNLHLMMASFYRPSAERAAILIEAGAFPSDRHAVESQLRLHGLDPDTHLIEVEPDAADGTLSMDAIAATIAQHGPRLALVLWPGIQYRTGQAFALGEIARLARAQGAAVGFDLAHAVGNIPLSLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHAHSNLPRMAGWWGHEQPTRFRMEPQFVPSPGAEGWQLSNPPVLALAPLRASLELFDQAGMPALRAKSEQLTGHLEQLIHTRVPQVLQIVTPADPAQRGCQLSLRVAGGRTQGRALFEYLQSVGVLGDWREPDVIRIAPVPLYNRFCDLHQLVEHVETWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
423 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.845 kDa
Sequence
MTDPLSRAHAAALDAADPLRNLRDAFVFPQHGDDDQTYFVGNSLGLQPRAARAMVDEVLDQWGALAVEGHFTGPTQWLTYHQLVGDALARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTAERGAILIEAGAFPSDRHAVESQLRLHGLDPATHLIEVEADEPNGTVSMSAIAEAIAQHGPHLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGLDLAHAVGNLPLTLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHATSDLPRMAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLALFDQAGMAALRAKSEQLTGHLEQMIHARVPQVLQIVTPVEPARRGCQLSLRVAGGRARGRALFEHLHAAGVLGDWREPDVIRIAPVPLYNRFSDLHTFVEQVEAWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Length
423 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.937 kDa
Sequence
MTDLLSRAHAVALDAADPLRGLRDAFVFPQHGDDDQTYFVGNSLGLQPRAARAMVDEVLDRWGALAVEGHFTGPTQWLTYHQLVRDGLARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTAERGAILIEAGAFPSDRHAVESQLRLHGLDPATHLIEVDADEPNGTVSMTAIAEAIAQHGPRLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGFDLAHAVGNLPLTLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHANSDLPRMAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLALFDQAGMAALRAKSEQLTGHLEQLIHARVPQALQIVTPAEPARRGCQLSLRVAGGRARGRALFEHLHAAGVLGDWREPDVIRIAPVPLYNRFSDLHTFVEQVEAWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Length
423 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.057 kDa
Sequence
MTDLLSRAHADALDAADPLRSLRDAFVFPQHGDRDQTYLVGNSLGLQPRAARAMVDEVLDQWGTLGVEGHFTGPTQWLTYHQLVRDALARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTHERGAILIEAGAFPSDRHAVESQLRLRGLDPATHLIEVEADEPNGTLSMAAIADAIAQHGPRLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGCDLAHAVGNIPLTLHDDGVDFAVWCNYKYLNAGPGAVGGCFVHERHANSDLPRIAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLALFDQTGMAALRAKSERLTGHLEQLIHARVPQVLQIVTPAEPMRRGCQLSLRVAGGRAQGCSLFEHLHAAGVLGDWREPDLIRIAPVPLYNRFSDLHTFVGQVEAWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas oryzae pv. oryzae (strain PXO99A)
Length
423 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.115 kDa
Sequence
MTDLLSRAHADALDAADPLRSLRDAFVFPQHGDRDQTYLVGNSLGLQPRAARAMVDEVLDQWGTLGVEGHFTGPTQWLTYHQLVRDALARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTHERGAILIEAGAFPSDRHAVESQLRLRGLDPATHLIEVEADEPNGTLSMAAIADAIAQHGPRLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGCDLAHAVGNIPLTLHDDGVDFAVWCNYKYLNAGPGAVGGCFVHERHANSDLPRIAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLTLFDQAGMAALRAKSERLTGHLEQLIRARVPQVLQIVTPAEPMRRGCQLSLRVAGGRAQGRSLFEHLHAAGVLGDWREPDVIRIAPVPLYNRFSDLHTFVGQVEAWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Length
423 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
46.096 kDa
Sequence
MTDLLSRAHADALDAADPLRSLRDAFVFPQHGDRDQTYLVGNSLGLQPRAARAMVDEVLDQWGTLGVEGHFTGPTQWLTYHQLVRDALARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTHERGAILIEAGAFPSDRHAVESQLRLRGLDPATHLIEVEADEPNGTLSMAAIADAIAQHGPRLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGCDLAHAVGNIPLTLHDDGVDFAVWCNYKYLNAGPGAVGGCFVHERHANSDLPRIAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLTLFDQAGMAALRAKSERLTGHLEQLIRARVPQVLQIVTPAEPMHRGCQLSLRVAGGRAQGRSLFEHLHAAGVLGDWREPDVIRIAPVPLYNRFSDLHTFVGQVEAWAAA
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia mallei (strain NCTC 10247)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.922 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADDEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia mallei (strain NCTC 10229)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.922 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADDEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia mallei (strain ATCC 23344)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.922 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADDEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia mallei (strain SAVP1)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.922 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADDEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia pseudomallei (strain 1106a)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.864 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADGEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia pseudomallei (strain 1710b)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.864 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADGEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia pseudomallei (strain 668)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.864 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADGEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Burkholderia pseudomallei (strain K96243)
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.898 kDa
Sequence
MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADGEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQFDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Pseudomonas fluorescens
Length
416 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
45.905 kDa
Sequence
MTTRNDCLALDAQDSLAPLRQQFALPEGVIYLDGNSLGARPVAALARAQAVIAEEWGNGLIRSWNSAGWRDLSERLGNRLATLIGARDGEVVVTDTTSINLFKVLSAALRVQATRSPERRVIVTETSNFPTDLYIAEGLADMLQQGYTLRLVDSPEELPQAIDQDTAVVMLTHVNYKTGYMHDMQALTALSHECGALAIWDLAHSAGAVPVDLHQAGADYAIGCTYKYLNGGPGSQAFVWVSPQLCDLVPQPLSGWFGHSRQFAMEPRYEPSNGIARYLCGTQPITSLAMVECGLDVFAQTDMASLRRKSLALTDLFIELVEQRCAAHELTLVTPREHAKRGSHVSFEHPEGYAVIQALIDRGVIGDYREPRIMRFGFTPLYTTFTEVWDAVQILGEILDRKTWAQAQFQVRHSVT
Protein
Kynureninase: kynU

Gene
kynU
Protein
Kynureninase
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Length
410 amino acids
Function
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Similarity
Belongs to the kynureninase family.
Mass
43.89 kDa
Sequence
MTTLLPALDLAQLDALDARDPLAHKRAEFDLPGDIIYLDGNSLGALPRRVPARLSQVATEEWGHHLIRSWTRNAEAAQDWMALPDRVAAKLAPLLGAGAHEVAVGDSTSVNTFKALAAALRLSGRRVILSDADNFPTDLYVAQGLARLLGDVEVRTAPGDEMTQHFTDDVGVVLLTEVDYRTGRRLDMRAITAAAHARGIVTVWDLAHSAGAFAVDLGGAGADFAIGCGYKFLNGGPGAPAFLYVAERHLDRAEVVLSGWMGHADPFEMARAYAPAPGARRFVVGTPQVLSLSALDAALDVFGDVDLGALREKSLSLTDTFIRLMEPLAEQYPLELVTPLAHAERGSQVSYRHPHAQQVMAQLIECGIVGDFRTPDILRFGFTPLYLSHGDVGRAVAGIAAVLDELEGPA
Protein
Kynureninase: kynU