Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Belongs to the kynureninase family.

425 amino acids

MTFQNTREFAKQLDAQDALNHYQEQFIFPKVNDKRVIYFTGNSLGLQPKRTKAYIDEVMNDWAELAVEGHFYAEKPWWDYQERFSEPLSKIVGALPSEVTVMNTLTVNLHLLMVSFYQPKGKRYKIICEEKAFPSDQYMFQSQVHFHGYKPEDAIVEIKRREGEHNIRLEDVLAKIEEVGDELALVLIGGVNYYTGQVFDIKTITAAGQKAGAKVGWDLAHAAGNIKLELHDWNVDFAAWCSYKYMNSGPGNASGVFVHERHHNDPDLPRFAGWWGHNKERRFKMEPNFDPVHGAGGWQISNLPVLSLAPYLASVEMFAEVGMDALIAKRDHITSYLEFILHEIDKEVESTFEIITPSNPEERASQLSVFLHGEGRSLFDYLMKNGVITDWREPNVIRLAPVPLYCSYEDMYDFGQILKKGILGK

48.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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