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gspS2

Gene
gspS2
Protein
Pilotin AspS 2
Organism
Escherichia coli O78:H11 (strain H10407 / ETEC)
Length
136 amino acids
Function
Part of a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane (Probable). Required for correct assembly of the type II secretion system-beta (T2SS-beta), for localization of GspD-beta to the cell outer membrane and for export of a labile entertoxin by T2SS-beta (PubMed:22585966). Each AspS2 binds to 2 GspD2 subunits and may clamp the monomers together, stabilizing structure and accelerating its assembly (PubMed:29632366).
Similarity
Belongs to the GspS/AspS pilotin family.
Mass
14.67 kDa
Sequence
MSIKQMPGRVLISLLLSVTGLLSGCASHNENASLLAKKQAQNISQNLPIKSAGYTLVLAQSSGTTVKMTIISEAGTQTTQTPDAFLTSYQRQMCADPTVKLMLTEGINYSITINDTRTGNQYQRKLDRTTCGIVKA