Protein
D-tagatose-1,6-bisphosphate aldolase subunit GatY
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Function
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol.
Similarity
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Sequence
MYIISSKNMLLKAQRQSYAVPAFNIHNLETMQVVVETAAELRSPLILAGTPGTYSYAGTGNVVAIARDLAKKWDLPLALHLDHHEDLADITRKVQAGIRSVMIDGSHSPFEENVALVKSVVELSHRYDASVEAELGRLGGVEDDLVVDAKDALYTNPEQAREFVARTGIDSLAVAIGTAHGLYTAEPKLDFERLAAIRDCVDVPLVLHGASGLPDSDIRRAISLGVCKVNVATELKIAFSDALKAYFLENPGANDPRHYMKPAKAAMKEVVRKVIHVCGCEGQL