Protein
D(2) dopamine receptor B
Function
This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. In Xenopus D2R is involved in the regulation of the melanotrope cells of the intermediate pituitary during background adaptation of the animal.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Sequence
EWRFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISVVWVLSFAISCPLLFGLNNTASTVCIIDNPAFVIYSSIVSFYVPFIVTLLVYVQIYIVLRKRRKRVNTKRNSHGVGVDAHKDKCTHPEDVKLCAVFVKSNGSFPAEKKKVEAGNHPEDMEMEMMSSTSPPEKTKHKSASPEHQLAVPATSNQCNNVNLPTPVNSPYKAENNGHSKDSTQPAKVFEIQSMPNGKTRTSIKTMSKRKISQHKEKKATQMLAIVLGVFIICWLPFFITHILNMHCNCNIPQALYSAFTWLGYVNSAVNPIIYTTFNVEFRKAFIKILHC