cyaB

Cyclolysin secretion/processing ATP-binding protein CyaB

712 amino acids

Involved in the export of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

Belongs to the ABC transporter superfamily. Cyclolysin exporter (TC 3.A.1.109.2) family.

77.646 kDa

MTSPVAQCASVPDSGLLCLVMLARYHGLAADPEQLRHEFAEQAFCSETIQLAARRVGLKVRRHRPAPARLPRAPLPAIALDRQGGYFVLARFEPGADQAVLIQRPGQAPARLGQAEFEALWAGELLLCACAASPTQALARFDFSWFIPALVKHRHLIGEVLLISLVLQFIALLTPLFFQVVMDKVLVNNAMETLNVIAVGFLAAILFEALLTGIRTYLFAHTSSKLDVELGARLYAHLLRLPLAYFQARRVGDSVARVRELEHIRAFLTGNAVTVLLDVVFSVVFIAVMFFYSVKLTLVVLAALPCYFLLSLVLTPVLRRRLDVKFNRGAENQAFLVETVSGIDTVKSLAVEPQWQRNWDRQLAGYVAAGLSVANVAMLANTGVTLISRLVALGVLWVGATEVVAQRMTVGELVAFNMLSGHVTQPVIRLAQLWNDFQQTGVSMQRLGDILNCRTEVAGDKAQLPALRGSIELDRVSFRYRPDAADALRNVSLRIAPGEVVGVVGRSGSGKSTLTRLIQRMFVADRGRVLIDGHDIGIVDSASLRRQLGVVLQESTLFNRSVRDNIALTRPGASMHEVVAAARLAGAHEFICQLPEGYDTMLGENGVGLSGGQRQRIGIARALIHRPRVLILDEATSALDYESEHIIQRNMRDICDGRTVIIIAHRLSAVRCADRIVVMEGGEVAECGSHETLLAAGGLYARLQALQAGEAG

cyaB

Cyclolysin secretion/processing ATP-binding protein CyaB

712 amino acids

Involved in the export of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

Belongs to the ABC transporter superfamily. Cyclolysin exporter (TC 3.A.1.109.2) family.

77.662 kDa

MTSPVAQCASVPDSGLLCLVMLARYHGLAADPEQLRHEFAEQAFCSETIQLAARRVGLKVRRHRPAPARLPRAPLPAIALDRQGGYFVLARFEPGADQAVLIQRPGQAPARLGQAEFEALWAGELLLCACAASPTQALARFDFSWFIPALVKHRHLIGEVLLISLVLQFISLLTPLFFQVVMDKVLVNNAMETLNVIAVGFLAAILFEALLTGIRTYLFAHTSSKLDVELGARLYAHLLRLPLAYFQARRVGDSVARVRELEHIRAFLTGNAVTVLLDVVFSVVFIAVMFFYSVKLTLVVLAALPCYFLLSLVLTPVLRRRLDVKFNRGAENQAFLVETVSGIDTVKSLAVEPQWQRNWDRQLAGYVAAGLSVANVAMLANTGVTLISRLVALGVLWVGATEVVAQRMTVGELVAFNMLSGHVTQPVIRLAQLWNDFQQTGVSMQRLGDILNCRTEVAGDKAQLPALRGSIELDRVSFRYRPDAADALRNVSLRIAPGEVVGVVGRSGSGKSTLTRLIQRMFVADRGRVLIDGHDIGIVDSASLRRQLGVVLQESTLFNRSVRDNIALTRPGASMHEVVAAARLAGAHEFICQLPEGYDTMLGENGVGLSGGQRQRIGIARALIHRPRVLILDEATSALDYESEHIIQRNMRDICDGRTVIIIAHRLSAVRCADRIVVMEGGEVAECGSHETLLAAGGLYARLQALQAGEAG

cyaB

Adenylate cyclase 2

352 amino acids

In the C-terminal section; belongs to the adenylyl cyclase class-3 family.

38.238 kDa

MLQGHHRVMVVDDSPLACDFVKEGLEALGLGYEVMCFQDPYEALEQVGKVQPAIVLSDLDMPGIDGLELCWRLKESPSRQVPVIILTANDSEAERVKGLRAGADDYVNKSASMAELSARIESVMRRTSETERMRKLFARYTSDAVVEEILKSPDTVVLTGEKPEVTVLFADIRNFTGLAESLPPEQVVGVLNQVLGRLSDAVLTCGGTLDKFLGDGLMAVWGAPVHRTDDALRALQAAKMMMTAMVELRQAAQAEWAANERLGRPLVLELGIGINSGLAVAGNIGGSMRTEYTCIGDAVNVAARLCALAGPGEILAGERTRELVSHREMPFEDLPPVRLKGKQQPVPLYRVL

cyaB

Ubiquinol oxidase subunit 2

307 amino acids

Belongs to the cytochrome c oxidase subunit 2 family.

33.921 kDa

MKNKLLARVARLGGLSSALLLAGCELDVLDPKGPVGEGVKTLIATSTVAMLIVVIPTILETLLFAWQYRQSNTSAEYLPKWCHSNKIEVTIWGVPSLIILFLAVITYQTCHSLDPYKPLEAEANTKPLHVEVVALDWKWLFIYPEQGIATVNQLAIPVNTPIDFNITSDSVMNSFFIPRLGSMIYAMAGMQTQLHLLASEPGDYLGESANYSGRGFSDMKFHTLAVSGDEFNAWVEKVKSSSEQLDSQTYPKLAAPSENPVEYFAHVEPGMFNTIVAKYNNGMVMDKSTGKMIQVQQSAMSDMNMKE

cyaB

Adenylate cyclase CyaB

191 amino acids

In vitro, CyaB catalyzes the biosynthesis of cyclic AMP (cAMP) from ATP. It seems that under the physiological conditions CyaB has no function in cAMP processes. In vitro, it is also able to hydrolyze substrates such as thiamine triphosphate (ThTP) and inorganic triphosphate (PPPi) at a low rate. It has a slight preference for ThTP over ATP and PPPi in the presence of manganese ions. This PPPase activity is probably not of physiological importance.

Belongs to the adenylyl cyclase CyaB family.

21.509 kDa

MSSQHFQGRFEVEFKYRLSDVDAFTCALAALNPEVMLEDNQEQDSYFDTPEHSLAAEGKSLVIRTMQPSGIQLWIVKGPEADRCEAVNITDADKAASMLRTLGYRQVLAISKRRSIYFVGPFHVTRDHLEGIGDFAELAIMTDDEALLPDYRQQLQDLATRLGLSSAQLETRSYRTLCEQSLTLNSEKVPS