Protein
Modification methylase BamHI
Organism
Bacillus amyloliquefaciens
Function
This methylase recognizes the double-stranded sequence GGATCC, causes specific methylation on C-5 on both strands, and protects the DNA from cleavage by the BamHI endonuclease.
Similarity
Belongs to the N(4)/N(6)-methyltransferase family.
Sequence
MRFFSVFDIVKNKANQLGYTETEMYAVLKNYNVNKKDLLAYKENGVIPTDKVLNGILSYLGMTKVELELKLGRIPAGLEDVFLNNTKEIAKILENKNSVKLNEFNSIQEIKPYFYTDLGKLYNGDCLELFKQVPDENVDTIFADPPFNLDKEYDEGVTDKNSFSGYLDWYYKWIDECIRVLKPGGSLFIYNIPKWNTYLSEYLNRKLNFRNWITVDMKFGLPIQNRLYPANYSLLYYVKGDKPKTFNVQRIPLQTCPHCGREIKDYGGYKNKMNPKGVTLSDVWSDIYPVRHSSSKNRKFNELSVKLLDRIITMSTNEGDVVLDPFGGSGTTFAVSEMLGRKWIGFELGNCEIIKERLKNKDKDKKLLGKVYEEKNKLFPNRVKELRKKNGLWIDDDFRQDHEGNSKGDKKNENNDQISLSLE