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aidA

Gene
AIDA
Protein
Axin interactor, dorsalization-associated protein
Organism
Homo sapiens
Length
306 amino acids
Function
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
Similarity
Belongs to the AIDA family.
Mass
35.023 kDa
Sequence
MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE

Gene
AIDA
Protein
Axin interactor, dorsalization-associated protein
Organism
Pongo abelii
Length
306 amino acids
Function
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
Similarity
Belongs to the AIDA family.
Mass
35.023 kDa
Sequence
MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE

Gene
Aida
Protein
Axin interactor, dorsalization-associated protein
Organism
Mus musculus
Length
305 amino acids
Function
Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
Similarity
Belongs to the AIDA family.
Mass
34.888 kDa
Sequence
MSEVTRSLLQRWGASLRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPIPLRRILAPGEEENLEFEEDEEGGAGAGPPDSFSARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVERLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQSLHKE

Gene
aidA
Protein
Quorum-quenching protein AidA
Organism
Acinetobacter baumannii (strain MDR-ZJ06)
Length
304 amino acids
Function
Involved in quorum quenching (QQ). Inhibits motility and biofilm formation. Could contribute in bacterial competition, as it is capable of hydrolyzing the signaling molecules that mediate interspecies communication.
Similarity
Belongs to the AB hydrolase superfamily.
Mass
33.365 kDa
Sequence
MGKSLNNVPQAPLDVQFDSNDVKCSAYLYRPTTEVATPMIVMAHGLGGTRRMRLTAFAERFVAEGYACLVFDYRYFGDSEGQPRQLLDIKSQLEDWKAAIAYARSLDKIDPNRVVIWGTSFGGGHVLATAANDNRLAAVISQCPFTDGFSSSMAMNPITTLKLMGLALKDKIGSILGAKPVMVPLAAPSGHTALMNAPDAYSGYLALMPSGSNIPNYVAARFVLDIIRYYPGRKTSRIQAPVLFCVCDTDSVAPSKTTLRHASHTPNHEIKHYADGHFEIYVGEAFERVVRDQIDFLKRIVPVK

Gene
aida
Protein
Axin interactor, dorsalization-associated protein
Organism
Danio rerio
Length
303 amino acids
Function
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by axin/JNK-signaling.
Similarity
Belongs to the AIDA family.
Mass
34.56 kDa
Sequence
MSDVNKTVQKWHASFKKGTDFDSWGQLVEAIDEYQILARQLQKEVQSSNSHDFTEEQKKTLGKFATCLEMRSAALQCTQSQEEFKLEDLKKLEPIIKNILTYNKDFPFDVQPVPLRKILAPGEEENLDVEEDLDAGTGAGSTPSFTSRLPGSLLPRLPSEPGMTLLTLTIEKIGLKDAGQCIDPYITVSVKDLNGIDLNPVQDTPVATRKEDTYIHFSVDVEIQRHLEKLPKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLNLLTKKPLYLHLNQTLHKD

Gene
AIDA
Protein
Axin interactor, dorsalization-associated protein
Organism
Macaca fascicularis
Length
275 amino acids
Function
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
Similarity
Belongs to the AIDA family.
Mass
31.494 kDa
Sequence
MFSSYRLARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE