Protein
Intron-encoded DNA endonuclease ai2a
Organism
Dictyostelium discoideum
Function
Mitochondrial DNA endonuclease involved in intron homing. Cleaves only one strand of intronless DNA sequence at the site which coincides with the I-SceII cleavage recognition site.
Similarity
Belongs to the LAGLIDADG endonuclease family.
Sequence
MKKEEKKENKKREQNQISSKKWNEWLAGLIDGAGKFTLSKSGYANLDILLELRDEKCHIELKQRFGGEIKRKETTLIRYRVHRLYGIRQLIACVNGHIRHPLRKIEFKEICMHYNVEYKEPETLTFANGWLSGYFDAVGLIEFSTEQDQLYLAFRHKKNTMLNELEIQKCLGVNLTCEQNGCSCESVTLYKINKKTVLSLYKYFKKYRLRSSIKTTQILLIPQFYEIQNETKEINDMQVKQKLWKQFFKKWYVDEMVKYESVKLANYYKSKTSPEKRVKKLIKLKFHRNERIRKRAERLELQKEKEKKA