aglB2

Dolichyl-phosphooligosaccharide-protein glycotransferase 2

758 amino acids

Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcXyl(2)GlcAMan(2)GalNAc in Pyrococcus) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.

Belongs to the STT3 family.

86.787 kDa

MKRRYSILIILLVAIFYRMITFRFKYLLGYDPYFHLAYIEEVNKVGKWINFLTFAGGPWGYQVKLFHPLGLWMTPLYLYKLLKVFGVSLTTTFKITPVIFGVLTVIFLYLSLLKLYDEKRAFFGGFFLAISYGHVFRSMANYYRGDNYMLFWYSVALLGISLALGIKKGKWKYKRLIFYTLPVLASGFSAIFWQAYYPIFAFLLSNALLLAVGAFILKKDKYLLDSIILILSTAFGVLLANYLGGIFGYGMLGYAKWLGKSVAKKLGLEFGYLKDVYLILHLKYLVPISLSFVLVLILLGFLTKDIRIRSLFLGIASFIGIIILFKRFEALKELSTGFGIFKEAPILETQPTSFKDLWAAFSLSFFLTPLFFIRFKKPRVEDFLTLGLIIPSVYMLKTWTRFLFIGSMAIAIMSGIGIVELYEAIKPRLNGKKALATGIITLVILPGVIAGLSFKEVCSLHPEMNEAWERALKWLKNNSNENDVILAWWDWGHFITYYARRSPIAQGGPSVGVALYLLGKLNENWAINLGVDYVIVSYYDFLKFGAILSTANLSKRYNIRGYGLVVLPLRASTGALIFENRGYRAIVRHDKSWNAVIIYNGQMIYPRKLYVEHKEGVQEIKPPESNSNTYLYVNLNYGYAIFMNGNAFNTTLVRLFITPEKPYKLVYSDGGLIKIFKLEHPNVKVERRESNVILNFENGTSLGLYFFLDNGTMVLSKWYNVKGKNEFIVPKVNASVARYVLKRGKKVVDRGVFRLSYN

aglB2

Dolichyl-phosphooligosaccharide-protein glycotransferase 2

743 amino acids

Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcXyl(2)GlcAMan(2)GalNAc in P.furiosus) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.

Belongs to the STT3 family.

84.342 kDa

MKIDKRLMVIVAIATLFRMIPFRLKYLVGSDPYFHLAYIEEALKAGEWFNFFTYAGGPWGLQVRLFHPLGLWATPAYIYKLFSFLGISLYTAFRVTPVIFGVLTVVFFYLSLKKLYNRDVAFIVGLFLGVNYGHIFRSMANYYRGDNYMLFWYSVALLGIALGLKTRSKYRYLFYLLPGIATGFASAFWQAYYPIFVFVLAGGLLLGVYAYLKSPKLFLDSILIVLSTGLGVLIANILGDKVGYGMLGYTDWMGKKVAETFGLEFGFIKDAYLLIHVKYLLPLSLVFLGFLIITKKLNPKIKVGVLVGGSILAFIVMLVKFPALKDLSTGFGTFREVPISETLPPTLDDLWRAYNIAIFLAALYILRLRKIRSGDAILLGYVITSLWMLRYWTRFLFTAAPAVAFLSGIGVYELTRRIKENKIRITSLGVVILLSSAFSLGEVYSVKPFMNENWEKALIFIRENSNENDIVLTWWDWGHFVTYYARRSPVAQGSPNSGVAGYYLGLVDNGWAQSLGVDYVIVSLYDILKFEAIVDTAKLSRKWENISRADYGVDFLKLTESTGSILRFDSQYSTLIVKEGNIRVILSGKVVYPREAIIESNGRIKNLKYPARSGVYVYVNLDYGYAILANEKAWETNLLRLFTQRTGENYELVYSDGGFVKVFRFVHPNVVFRGNKFILTGNGTGLGLYGYLDNGTLVFKKWYSVKNMQEFELPNNLNGSVVVRYVYTQGKIVLDRGIVRVKN

aglB2

Dolichyl-phosphooligosaccharide-protein glycotransferase 2

593 amino acids

Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (a GalNAc-linked heptasaccharide composed of 4 Hex, 3 dHex and a sulfate for A.fulgidus AglB-S) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.

Belongs to the STT3 family.

68.172 kDa

MTPVGMDRKSLSLLILIVLLGLCIRLQNFGEIFDSRIYYYGYDPYYHMRLVEAIVLEGYRPSFDYYINYPYGLRIDWLPLFDYILAFPGLFLGFWASEIFAVVFPVIIGVLCIVLVYLISLEVLRNEKFALISAFIFSVCPVTVWKSLLGKADHHIWVVFLLLLSIWLVTKPGLLKLLSGIPMLLMALSWLGAPIYAALLAVSSLFQFNEKEVRIVGISNLIPVLSSIQNLFLGFSFLAIAVFLLVGSFVKRFERRFRYAIVYYLCICSVALLSAYLMPVGWLGFVKSGISYVLGTDIYLPTIREARSFQILGVISSAGYLFFVLAIPALFMLRNGFLKVFFVLSFLISILQLRFVEVLAFPVAILASYTICQILERVDYPVFRKEEEGESKRRGRKEKKKAVEIRKKDHATVIAFLLFLALPCFANSLAPVEMTMDWKEALNWMKENLEAQDYLKAYEKPDYAVLSWWDYGNWILYVAKKAVVCNNFQAGADDAAKFFTAQSEEEAMKIVEKRKVRYVVTVEELTVKPETNKTKFIPIMQIAGYSPEYMKNKEIIDFFNKTMLYKLHVENATNLTHFRLLKNFGTVKIFEVK