aglB1

Dolichyl-phosphooligosaccharide-protein glycotransferase 1

976 amino acids

Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcXyl(2)GlcAMan(2)GalNAc in Pyrococcus) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.

Belongs to the STT3 family.

109.97 kDa

MVKSKVKKVEKGKEGEEKRSTYVLLKKVLIPILVFGFAIYAFYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPRYYPMSDAPFGSLIGEPLGLYLLPAAFYKVVSLFGYNELQAFLLWPPFVGFLGVIAVYLLGRKVLNEWTGLWGAVVLTVSTANFSRTFSGNARGDGPFMALFIFASVAMLYYLKESNKTRKIIYGTLFVLLTVISLGAWNGSPFGLMVLLGFASLQTIILFIFGKLEELKKFVKEFYPAYLAILAFGYALTFPGIVKIGGFIRFAFEVFLGLIFLLVIMLYGGRYLNYSDKKHRFLVVTIIVLLGFGGAYAYVGPKLFRLMGGAYQSTQVYETVQELAKTTIGDVKAYYGVESGNGLIFFLSIPGLLILLTKYLYDLFKKAKSDNETLFALVFYTMSLYLLYLAVRFLFLASYAVALFFGIFIGFSMDVIEKMKENIGIKAALGIVLSLMILVIPFVHAPVLARSARALKNTEIEVTGWEQALKWLRSNTSKYATATSWWDYGYWIESSLLGNRRASADGGHARDRDHILALFLARDGNISEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRKEYNGDENGRGRVTTILLTQAAGNVYVNPYARIVIKVIQQNKTRRIAVNIGQLECSPILSVAFPGNIKIKGSGRCSDGSPFPYVVYLTPSLGVLAYYKVATSNFVKLAFGIPTSSYSEFAEKLFSNFIPVYQYGSVIVYEFRPFAIYKIEDFINGTWREVGKLSPGKHTLRLYISAFGRDIKNATLYVYALNGTKIIKRIKVGEIKYMNHLEEYPIIVNVTLPTAQKYRFILAQKGPVGVLTGPVRVNGKITNPAYIMREGESGRLELKVGVDKEYTADLYLRATFIYLVRKGGKSNEDYDASFEPHMDTFFITKLKEGIKLRPGENEIVVNAEMPKNAISSYKEKLEKEHGDKLIIRGIRVEPVFIVEKEYTMIEVSASAPHHSSE

aglB1

Dolichyl-phosphooligosaccharide-protein glycotransferase 1

967 amino acids

Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcXyl(2)GlcAMan(2)GalNAc in P.furiosus) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.

Belongs to the STT3 family.

108.585 kDa

MVKTQIKEKKKDEKVTIPLPGKIKTVLAFLVVLAFAAYGFYIRHLTAGKYFSDPDTFYHFEIYKLVLKEGLPRYYPMADAPFGSLIGEPLGLYILPAIFYKIISIFGYNELEAFLLWPPFVGFLSVIGVYLLGRKVLNEWAGMWGAIILSVLTANFSRTFSGNARGDGPFMMLFTFSAVLMLYYLTEENKNKKIIWGTLFVLLAGISTAAWNGSPFGLMVLLGFASFQTIILFIFGKINELREFIKEYYPAYLGILAISYLLTIPGIGKIGGFVRFAFEVFLGLVFLAIVMLYGGKYLNYSDKKHRFAVVAVIVIAGFAGAYIYVGPKLFTLMGGAYQSTQVYETVQELAKTDWGDVKVYYGVEKPNGIVFFLGLVGAMIVTARYLYKLFKDGRRPHEELFAITFYVMSIYLLWTAARFLFLASYAIALMSGVFAGYVLETVEKMKESIPIKAALGGVIAIMLLLIPLTHGPLLAQSAKSMRTTEIETSGWEDALKWLRENTPEYSTATSWWDYGYWIESSLLGQRRASADGGHARDRDHILALFLARDGNISEVDFESWELNYFLVYLNDWAKFNAISYLGGAITRREYNGDESGRGAVTTLLPLPRYGEKYVNLYAKVIVDVSNSSVKVTVGDRECDPLMVTFTPSGKTIKGTGTCSDGNAFPYVLHLTPTIGVLAYYKVATANFIKLAFGVPASTIPGFSDKLFSNFEPVYESGNVIVYRFTPFGIYKIEENINGTWKQVYNLTPGKHELKLYISAFGRDIENATLYIYAINNEKIIEKIKIAEISHMDYLNEYPIAVNVTLPNATSYRFVLVQKGPIGVLLDAPKVNGEIRSPTNILREGESGEIELKVGVDKDYTADLYLRATFIYLVRKSGKDNEDYDAAFEPQMDVFFITKIGENIQLKEGENTVKVRAELPEGVISSYKDELQRKYGDKLIIRGIRVEPVFIAEKEYLMLEVSASAPHH

aglB1

Dolichyl-phosphooligosaccharide-protein glycotransferase 1

591 amino acids

Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (a GalNAc-linked heptasaccharide composed of 4 Hex, 3 dHex and a sulfate for A.fulgidus AglB-S) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.

Belongs to the STT3 family.

67.539 kDa

MDRKVLMLAVILFALAVRFQNFGEIFDSGIYYTGYDSYYHMRLVEVMVKESFRPDYDYYINYPFGLKITWPPLFDYILAFPGMLFGFHSSEIFAVFLPVILGVLSVVLICLTALQIVNNQTFALISAFIYAAAPVAVWKTVLGQADHHALVIFLFLLSAYLLLKDGVWKILAGLPMLFMALAWLGSPIYGALLAFSALVHFDRKALRLVAASYLIPAISFVLYPPVGISFFGLAAFLFVGSVVKGYEDRFRNATIYYIALSLATVLIIYFIPLPHFEFVKGGINYIFGANIYLPTISEARSLQIFEIISASGYIYFIFALISVLFFRNRFVLSMFFLSFILALMQLRFTEVLVVPSALLSAYLVSLVLERLEYPVFEKADEEEKSRRRKRKDRKVKQKNAEVEWKDHAVVAAFLVILAIPCIVVAVVPFDLTEDWKEALEWMRTSLEEQNYLNPYEKPEYSVMSWWDYGNWILYVSKKAVVCNNFQAGAVDAAKFFTAKSEDEAIKIAKKRGVRYVVTADEITMKDANNTKFPAIMRIAGYNVDLMTEGEILNFFNHTVLYRLHMENAENLTHFRLVKEFGDVKIFEVVGS