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aftC

Gene
aftC
Protein
Alpha-(1->3)-arabinofuranosyltransferase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
433 amino acids
Function
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG.
Mass
48.915 kDa
Sequence
MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVLHRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGGTLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPALILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDGRASRQWCGGLAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALPLVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTAITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFPFLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFNWMRWGRALEYLKITYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTPEREGQR

Gene
aftC
Protein
Alpha-(1->3)-arabinofuranosyltransferase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
433 amino acids
Function
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. It can also use (Z,Z)-farnesylphosphoryl D-arabinose (Z-FPA), and to a lesser extent (E,E,Z,Z,Z,Z)-heptaprenylphosphoryl D-arabinose (Z-HPA) and (Z)-nerylphosphoryl D-arabinose (Z-NPA) as sugar donors.
Mass
48.915 kDa
Sequence
MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVLHRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGGTLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPALILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDGRASRQWCGGLAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALPLVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTAITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFPFLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFNWMRWGRALEYLKITYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTPEREGQR

Gene
aftC
Protein
Alpha-(1->3)-arabinofuranosyltransferase
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length
430 amino acids
Function
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG.
Similarity
Belongs to the glycosyltransferase 87 family.
Mass
48.768 kDa
Sequence
MYCALVTATDSITTKLLNAFRPRTSAPSTATVLRSVLWPIAILSVIHRSYVLGTNGYITDDFGPVYRAVINFKLGLDIYNEQFDHVDPHYLYPPGGTLLLAPFGYLPVDASRYWYISFNVLAFLIAAYLMLRIFDYTLSSVAAPALVLAMFCTESVTNTLVFTNINGCMLLGAVLFFRWLLKGGRNAELLAGAAIGLTLVVKPSLAPLLLLPVLNRQFYTLITAFGVPLVFNIAAWPLVPDPMNFVRHTVPYIMSTRDYFNSSIVGNGIYYGLPMWLILLLRVVFLLLAVGSLWLLYRYYRERDPRFWLLTSSGVLLTASFLLLSLGQGYYSTMLFPFLMTVVLPNSVLRNWPAWLAIYGFMTMDRWLLGHWPTTGRFLEYMKITYGWSLMLVVVFCVLYFRYLDAKQDGRLDQGIDPPWMARERTPAPV

Gene
aftC
Protein
Alpha-(1->3)-arabinofuranosyltransferase
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Length
279 amino acids
Function
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG.
Similarity
Belongs to the glycosyltransferase 87 family.
Mass
29.952 kDa
Sequence
MLVQSRTLVTAILSCSLVFGTTVNGASVAIAQENVPMAALYEPDYESLETRLGSINNDAGLPNSVSQTVENFAELPEGTRFVLDSDTFAVAVSDGVVTSRLDSQTGVIRHTFGGAGTISYNPGEVTRSYIDRVTVRVVYPDSSIDIVTPHSVVEVSDSFYYSVQSIDSQRVRNGQSIKVPMTVIAGDGAIGGVPQGAKVVRDRYGSVEDAELMGATIVIDEKTGELTFTAPEDRTGQMWFAAELIYPDGTYSEVHYLFEVTDKSVQDDSVPFFGSSLSS