Protein
Acetylcholine receptor subunit alpha-type acr-16
Organism
Caenorhabditis briggsae
Function
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. A subunit of the levamisole-insensitive nicotinic receptor (By similarity).
Similarity
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
Sequence
MSSVCALLLSCALFLVAHGSLQERRLYEDLMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWKDYNLVWDQAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNMIVYSSGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLDLQPATGGFDISEYLPNGEWALPLTTVERNEKFYDCCPEPYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPDAGEKITLQITVLLSICFFLSIVSEMSPPTSEAVPLLGIFFTCCMIVVTASTVFTVYVLNLHYRTPETHDMGPWTRNLLLYWIPWILRMKRPGHNLTYASLPSLFASKPNRHSESLIRNIKDNEHSLSRANSFDADCRLNQYIMTQSVSNGLTSMGSIPSTMISSTNGALTDVSQQATLLILHRIYHELKIVTKRMIEGDKEEQASNNWKFAAMVVDRLCLYVFTIFIIASTIGIFWSAPYLVA