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aciA

Gene
aciA
Protein
Formate dehydrogenase
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
365 amino acids
Function
Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
Similarity
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
Mass
40.131 kDa
Sequence
MGKVLMVLYDGGSHAKDQPGLLGTTENELGIRKWIEEQGHTLVTTSDKDGENSTFDKELVDAEVIITTPFHPGYLTAERLAKAKNLKLAVTAGIGSDHVDLDAANKTNGGITVAEVTGSNVVSVAEHVVMTILLLVRNFVPAHDQIRNGDWNVAAVAKNEFDLENKVVGTVGVGRIGERVLRRLKPFDCKELLYYDYQPLRPEVEKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPKEHPLRYAEHPWGGGNATVPHMSGTSIDAQIRYANGTKAILDSYFSGRFDYQPQDLIVHGGDYATKAYGQREKK