Protein
Modification methylase AccI
Organism
Acinetobacter calcoaceticus
Function
This methylase recognizes the double-stranded sequence GTMKAC, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the AccI endonuclease.
Similarity
Belongs to the N(4)/N(6)-methyltransferase family.
Sequence
MIKTTEHIVNNSIERDYSKSISLEHRKKFAQFFTPFPIAYAMAKWILGNKQLKTVLEPAFGLGVFSRAILSQQKEINIKAFEVDETIFENAKEYFDDFENVNILLQDYMYNDWKNKYDGIICNPPYFKFHDYDNKNILKEIETNLKCKLNGFTNLYTLFLLKSIHQLSQNGRCAYIIPSEFLNSDYGKLVKTYLIKSKTLRHIIVIDFEENVFDDALTTASIILCANDNITDKVQFNNIQSLQDLSKIDEIINKYPNFLETEQTYNFSDLNPEIKWKAYYQKQNSIKFKNLVPFSTYAKVVRGIATGSNEYFTFNLSKAKEFNIDEQYLLPCICSAKDAKTSFFTKQDFEELKKSDKSVFLFNAQNSTDKNISSYIQKGESEEINKRFLTASRTPWYSLENRKPAPIWVSVFNRSGLRFIRNEANISNLTSYHCIIQNKQVVSEIDIDLLFAYLLTDTAKQIFEDNSRQYGNGLQKFEPNDLNKGMMLDLGLLDKQTSDEILNLYKEYKYLILDNKNGDEIINKIDKILTDKYSEKKHWA